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Original Research

Use of Streptococcus salivarius K12 in the prevention of streptococcal and viral pharyngotonsillitis in children

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Pages 15-20 | Published online: 13 Feb 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Ismail Erol, Seyfullah Enes Kotil, Fatih Ortakci & Serdar Durdagi. (2023) Exploring the binding capacity of lactic acid bacteria derived bacteriocins against RBD of SARS-CoV-2 Omicron variant by molecular simulations. Journal of Biomolecular Structure and Dynamics 41:20, pages 10774-10784.
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Munirah Mokhtar, Nurul Alia Risma Rismayuddin, Aini Syahida Mat Yassim, Hasna Ahmad, Ridhwan Abdul Wahab, Stuart Dashper & Mohd Hafiz Arzmi. (2021) Streptococcus salivarius K12 inhibits Candida albicans aggregation, biofilm formation and dimorphism. Biofouling 37:7, pages 767-776.
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Giulia Marini, Emanuela Sitzia, Maria Laura Panatta & Giovanni Carlo De Vincentiis. (2019) Pilot study to explore the prophylactic efficacy of oral probiotic Streptococcus salivarius K12 in preventing recurrent pharyngo-tonsillar episodes in pediatric patients. International Journal of General Medicine 12, pages 213-217.
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Jean-François Stalder, Joachim W. Fluhr, Tim Foster, Martin Glatz & Ehrhardt Proksch. (2019) The emerging role of skin microbiome in atopic dermatitis and its clinical implication. Journal of Dermatological Treatment 30:4, pages 357-364.
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Seraj Zohurul Haque & Mainul Haque. (2017) The ecological community of commensal, symbiotic, and pathogenic gastrointestinal microorganisms – an appraisal. Clinical and Experimental Gastroenterology 10, pages 91-103.
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Francesco Di Pierro, Maria Colombo, Alberto Zanvit & Amilcare S Rottoli. (2016) Positive clinical outcomes derived from using Streptococcus salivarius K12 to prevent streptococcal pharyngotonsillitis in children: a pilot investigation. Drug, Healthcare and Patient Safety 8, pages 77-81.
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Francesco Di Pierro, Daniele Di Pasquale & Maurizio Di Cicco. (2015) Oral use of Streptococcus salivarius K12 in children with secretory otitis media: preliminary results of a pilot, uncontrolled study. International Journal of General Medicine 8, pages 303-308.
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Francesco Di Pierro, Alberto Zanvit, Piero Nobili, Paolo Risso & Carlo Fornaini. (2015) Cariogram outcome after 90 days of oral treatment with Streptococcus salivarius M18 in children at high risk for dental caries: results of a randomized, controlled study. Clinical, Cosmetic and Investigational Dentistry 7, pages 107-113.
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Daniel Penela‐Sánchez, Muntsa Rocafort, Desiree Henares, Iolanda Jordan, Pedro Brotons, María Cabrerizo, Cristian Launes & Carmen Muñoz‐Almagro. (2023) Impact of the bacterial nasopharyngeal microbiota on the severity of genus enterovirus lower respiratory tract infection in children: A case–control study. Pediatric Pulmonology 58:6, pages 1728-1737.
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John R. Tagg, Liam K. Harold, Rohit Jain & John D. F. Hale. (2023) Beneficial modulation of human health in the oral cavity and beyond using bacteriocin-like inhibitory substance-producing streptococcal probiotics. Frontiers in Microbiology 14.
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Alexander Bertuccioli, Marco Gervasi, Giosuè Annibalini, Beatrice Binato, Fabrizio Perroni, Marco B. L. Rocchi, Davide Sisti & Stefano Amatori. (2023) Use of Streptococcus salivarius K12 in supporting the mucosal immune function of active young subjects: A randomised double-blind study. Frontiers in Immunology 14.
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Sharbari Dutta & Abinash Mohapatra. (2023) Early childhood caries- Etiology, prevention and management: A Review. Archives of Dental Research 12:2, pages 81-88.
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Francesco La Torre, Jurgen Sota, Antonella Insalaco, Giovanni Conti, Emanuela Del Giudice, Riccardo Lubrano, Luciana Breda, Maria Cristina Maggio, Adele Civino, Violetta Mastrorilli, Roberta Loconte, Marco Francesco Natale, Camilla Celani, Mery Romeo, Serena Patroniti, Cristina Gentile, Antonio Vitale, Valeria Caggiano, Carla Gaggiano, Federico Diomeda, Marco Cattalini, Giuseppe Lopalco, Giacomo Emmi, Paola Parronchi, Stefano Gentileschi, Fabio Cardinale, Emma Aragona, Farhad Shahram, Achille Marino, Patrizia Barone, Carla Moscheo, Burcugul Ozkiziltas, Francesco Carubbi, Ohoud Alahmed, Ludovica Iezzi, Benson Ogunjimi, Angela Mauro, Maria Tarsia, Ayman Abdel-Monem Ahmed Mahmoud, Henrique Ayres Mayrink Giardini, Petros P. Sfikakis, Katerina Laskari, Ewa Więsik-Szewczyk, José Hernández-Rodríguez, Bruno Frediani, Verónica Gómez-Caverzaschi, Abdurrahman Tufan, Ibrahim A. Almaghlouth, Alberto Balistreri, Gaafar Ragab, Claudia Fabiani, Luca Cantarini & Donato Rigante. (2023) Preliminary data revealing efficacy of Streptococcus salivarius K12 (SSK12) in Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome: A multicenter study from the AIDA Network PFAPA syndrome registry. Frontiers in Medicine 10.
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Yuxing Wang, Zhuangzhuang Liang, Fang Shen, Wenting Zhou, Tabusi Manaer, Didaier Jiaerken & Xinhua Nabi. (2023) Exploring the immunomodulatory effects and mechanisms of Xinjiang fermented camel milk-derived bioactive peptides based on network pharmacology and molecular docking. Frontiers in Pharmacology 13.
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Francesco Di Pierro, Somia Iqtadar, Sami Ullah Mumtaz, Alexander Bertuccioli, Martino Recchia, Nicola Zerbinati & Amjad Khan. (2022) Clinical Effects of Streptococcus salivarius K12 in Hospitalized COVID-19 Patients: Results of a Preliminary Study. Microorganisms 10:10, pages 1926.
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Yunli Zhao, Bi Rong Dong & Qiukui Hao. (2022) Probiotics for preventing acute upper respiratory tract infections. Cochrane Database of Systematic Reviews 2022:8.
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J.D.F. HaleR. JainP.A. WescombeJ.P. BurtonR.R. SimonJ.R. Tagg. (2022) Safety assessment of Streptococcus salivarius M18 a probiotic for oral health . Beneficial Microbes 13:1, pages 47-60.
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Rebecca E. Moore, Harrison C. Thomas, Shannon D. Manning, Jennifer A. Gaddy & Steven D. Townsend. (2021) Galacto‐Oligosaccharide Supplementation Modulates Pathogen‐Commensal Competition between Streptococcus agalactiae and Streptococcus salivarius . ChemBioChem 23:3.
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Guochao Jia, Xiaofeng Liu, Aimin Zhi, Jingjing Li, Yuanfeng Wu & Yao Zhang. (2021) Characterization and Selection of Lactobacillus plantarum and Lactobacillus paracasei for prevention of oral bacterial infections from Chinese pickle. AMB Express 11:1.
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