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Diabetes, Metabolic Syndrome and Obesity Volume 12, 2019 - Issue
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Original Research

2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione isolated from Averrhoa carambola L. root ameliorates diabetic nephropathy by inhibiting the TLR4/MyD88/NF-κB pathway

Shunyu Lu1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Hongliang Zhang1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Xiaojie Wei1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Xiang Huang1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Lixiu Chen1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Luhui Jiang1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Xingchun Wu1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Xing Zhou1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Luhui Qin1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Yuchun Li1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
,
Xing Lin1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China
&
Renbin Huang1 Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Pages 1355-1363 | Published online: 07 Aug 2019

Citations (11)

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Luhui Qin, Xiaolin Zhang, Xing Zhou, Xingchun Wu, Xiang Huang, Ming Chen, Yani Wu, Shunyu Lu, Hongliang Zhang, Xiaohui Xu, Xiaojie Wei, Shijun Zhang & Renbin Huang. (2020) Protective Effect of Benzoquinone Isolated from the Roots of Averrhoa carambola L. on Streptozotocin-Induced Diabetic Mice by Inhibiting the TLR4/NF-κB Signaling Pathway. Diabetes, Metabolic Syndrome and Obesity 13, pages 2129-2138.
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Articles from other publishers (10)

Xin Zhang, Anran Wang, Enhui Chang, Bei Han, Jie Xu, Yu Fu, Xiaojing Dong & Shuyan Miao. (2023) Effects of dietary tryptophan on the antioxidant capacity and immune response associated with TOR and TLRs/MyD88/NF-κB signaling pathways in northern snakehead, Channa argus (Cantor, 1842). Frontiers in Immunology 14.
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Miao-miao Chen, Jin-hao Jia, Yu-jun Tan, Yu-shan Ren, Jun-lin Lv, Ting Chu, Xin-yue Cao, Ru Ma, De-fang Li, Qiu-sheng Zheng, Zhong Liu & Jie Li. (2023) Shen-Qi-Jiang-Tang granule ameliorates diabetic nephropathy via modulating tumor necrosis factor signaling pathway. Journal of Ethnopharmacology 303, pages 116031.
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Tao Jiang, Sile Shen, Liang Wang, Mingzhi Zhao, Yangyan Li & Shuting Huang. (2022) Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway. Applied Biochemistry and Biotechnology 194:9, pages 4093-4104.
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Chongbin Liu, Ming Yang, Li Li, Shilu Luo, Jinfei Yang, Chenrui Li, Huafeng Liu & Lin Sun. (2022) A Glimpse of Inflammation and Anti-Inflammation Therapy in Diabetic Kidney Disease. Frontiers in Physiology 13.
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Lihui Wang, Jinjin Cao, Qianqian Xu, Xiaomei Lu, Xin Yang, Qiong Song, Shuai Chen, Kechen Du, Renbin Huang & Chunlin Zou. (2021) 2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione Ameliorates Diabetic Cognitive Impairment Through Inhibiting Hif3α and Apoptosis. Frontiers in Pharmacology 12.
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Fei Luan, Lixia Peng, Ziqin Lei, Xiyu Jia, Junbo Zou, Yan Yang, Xirui He & Nan Zeng. (2021) Traditional Uses, Phytochemical Constituents and Pharmacological Properties of Averrhoa carambola L.: A Review. Frontiers in Pharmacology 12.
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Kasun Lakmal, Pamodh Yasawardene, Umesh Jayarajah & Suranjith L Seneviratne. (2021) Nutritional and medicinal properties of Star fruit ( Averrhoa carambola ): A review . Food Science & Nutrition 9:3, pages 1810-1823.
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Lihui Wang, Xin Yang, Qiong Song, Jiejun Fu, Wenchu Wang, Kechen Du, Shuai Chen, Jinjin Cao, Renbin Huang & Chunlin Zou. (2021) Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evaluation. Frontiers in Pharmacology 12.
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Laura Cornara, Jianbo Xiao, Antonella Smeriglio, Domenico Trombetta & Bruno Burlando. (2020) Emerging Exotic Fruits: New Functional Foods in the European Market. eFood 1:2, pages 126-139.
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Saleem Aladaileh, Sultan Saghir, Kisantini Murugesu, Amirin Sadikun, Ashfaq Ahmad, Gurjeet Kaur, Ayman Mahmoud & Vikneswaran Murugaiyah. (2019) Antihyperlipidemic and Antioxidant Effects of Averrhoa Carambola Extract in High-Fat Diet-Fed Rats. Biomedicines 7:3, pages 72.
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