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Diabetes, Metabolic Syndrome and Obesity Volume 14, 2021 - Issue
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Original Research

Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake as a Mechanism

Xiaozhuo Chen1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USA;5 Heritage College of Osteopathic Medicine, Athens, OH, 45701, USA;6 Interdisciplinary Graduate Program in Molecular and Cellular Biology, Athens, OH, 45701, USA;7 Department of Chemistry and Biochemistry, Athens, OH, 45701, USAView further author information
,
Nigel A Daniels1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USA;5 Heritage College of Osteopathic Medicine, Athens, OH, 45701, USA;8 Department of Specialty Medicine, Athens, OH, 45701, USAView further author information
,
David Cottrill2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
,
Yanyang Cao2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
,
Xuan Wang2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
,
Yunsheng Li2 The Edison Biotechnology Institute, Athens, OH, 45701, USAView further author information
,
Pratik Shriwas2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
,
Yanrong Qian2 The Edison Biotechnology Institute, Athens, OH, 45701, USAView further author information
,
Michael W Archer1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USAView further author information
,
Nicholas B Whitticar4 Department of Biomedical Sciences, Athens, OH, 45701, USA;9 Translational Biomedical Sciences Program, Ohio University, Athens, OH, 45701, USAView further author information
,
Ishrat Jahan1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USAView further author information
,
Craig S Nunemaker1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USA;5 Heritage College of Osteopathic Medicine, Athens, OH, 45701, USACorrespondence[email protected]
View further author information
&
Aili Guo10 Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of California at Davis (UC Davis) School of Medicine, UC Davis Health Science, Sacramento, CA, 95817, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1061-5135View further author information
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Pages 759-772 | Published online: 24 Feb 2021

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