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Original Research
Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake as a Mechanism
Xiaozhuo Chen1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USA;5 Heritage College of Osteopathic Medicine, Athens, OH, 45701, USA;6 Interdisciplinary Graduate Program in Molecular and Cellular Biology, Athens, OH, 45701, USA;7 Department of Chemistry and Biochemistry, Athens, OH, 45701, USAView further author information
, Nigel A Daniels1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USA;5 Heritage College of Osteopathic Medicine, Athens, OH, 45701, USA;8 Department of Specialty Medicine, Athens, OH, 45701, USAView further author information
, David Cottrill2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
, Yanyang Cao2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
, Xuan Wang2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
, Yunsheng Li2 The Edison Biotechnology Institute, Athens, OH, 45701, USAView further author information
, Pratik Shriwas2 The Edison Biotechnology Institute, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USAView further author information
, Yanrong Qian2 The Edison Biotechnology Institute, Athens, OH, 45701, USAView further author information
, Michael W Archer1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USAView further author information
, Nicholas B Whitticar4 Department of Biomedical Sciences, Athens, OH, 45701, USA;9 Translational Biomedical Sciences Program, Ohio University, Athens, OH, 45701, USAView further author information
, Ishrat Jahan1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USAView further author information
, Craig S Nunemaker1 The Diabetes Institute at Ohio University, Athens, OH, 45701, USA;3 Department of Biological Sciences, Athens, OH, 45701, USA;4 Department of Biomedical Sciences, Athens, OH, 45701, USA;5 Heritage College of Osteopathic Medicine, Athens, OH, 45701, USACorrespondence[email protected]
View further author information
& View further author information
Aili Guo10 Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of California at Davis (UC Davis) School of Medicine, UC Davis Health Science, Sacramento, CA, 95817, USACorrespondence[email protected]
https://orcid.org/0000-0002-1061-5135View further author information
Pages 759-772
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Published online: 24 Feb 2021
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