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Original Research

An efficient and long-acting local anesthetic: ropivacaine-loaded lipid-polymer hybrid nanoparticles for the control of pain

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Pages 913-920 | Published online: 31 Jan 2019

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Read on this site (9)

Shuo Zhang, Yishu Wang, Shuai Zhang, Chengqi Huang, Qiyang Ding, Ji Xia, Daocheng Wu & Wei Gao. (2023) Emerging Anesthetic Nanomedicines: Current State and Challenges. International Journal of Nanomedicine 18, pages 3913-3935.
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Wen-Shang Liu, Yu Liu, Jie Gao, Hao Zheng, Zheng-Mao Lu & Meng Li. (2023) Biomembrane-Based Nanostructure- and Microstructure-Loaded Hydrogels for Promoting Chronic Wound Healing. International Journal of Nanomedicine 18, pages 385-411.
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He Ma, Zhenxiang Pan, Bingjie Lai, Chunfang Zan & He Liu. (2023) Recent Research Advances in Nano-Based Drug Delivery Systems for Local Anesthetics. Drug Design, Development and Therapy 17, pages 2639-2655.
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Fengming Tan, Lulu Xu, Yanling Liu, Huan Li, Dahan Zhang, Cuiying Qin, Yang Han & Jing Han. (2022) Design of hydroxy-α-sanshool loaded nanostructured lipid carriers as a potential local anesthetic. Drug Delivery 29:1, pages 743-753.
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Tao Jiang, Shuangshuang Ma, Yangyang Shen, Yuwen Li, Ruirui Pan & Huaixin Xing. (2021) Topical anesthetic and pain relief using penetration enhancer and transcriptional transactivator peptide multi-decorated nanostructured lipid carriers. Drug Delivery 28:1, pages 478-486.
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Articles from other publishers (14)

Ye Tian, Yong Zhan, Ke Liu, Shaojin Bu, Yalin Tian, Chunyan Xiong & Jintao Shen. (2022) Analgesic effects of different concentrations of ropivacaine in transversalis fascia plane block during laparotomy. BMC Anesthesiology 22:1.
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Fei Peng, Jing Liu, Yujun Zhang, Jing Fan, Deying Gong, Liu He, Wensheng Zhang & Feng Qiu. (2022) Designer self-assembling peptide nanofibers induce biomineralization of lidocaine for slow-release and prolonged analgesia. Acta Biomaterialia 146, pages 66-79.
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Yang Yang, Jiaxiao Sun, Fei Peng, Haibei Liu, Guoyan Zhao, Junjie Chen, Wensheng Zhang & Feng Qiu. (2022) Enhanced Antitumor Activity of Lidocaine Nanoparticles Encapsulated by a Self-Assembling Peptide. Frontiers in Pharmacology 13.
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Shih-Jyun Shen, Ying-Chao Chou, Shih-Chieh Hsu, Yu-Ting Lin, Chia-Jung Lu & Shih-Jung Liu. (2022) Fabrication of Ropivacaine/Dexamethasone-Eluting Poly(D, L-lactide-co-glycolide) Microparticles via Electrospraying Technique for Postoperational Pain Control. Polymers 14:4, pages 702.
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Saurabh Shah, Paras Famta, Rajeev Singh Raghuvanshi, Shashi Bala Singh & Saurabh Srivastava. (2022) Lipid polymer hybrid nanocarriers: Insights into synthesis aspects, characterization, release mechanisms, surface functionalization and potential implications. Colloid and Interface Science Communications 46, pages 100570.
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Siddhi Lokhande, Ujwala A. Shinde, Agnivesh Shrivastava & Kavita H. Singh. 2022. Nanocarriers for Drug-Targeting Brain Tumors. Nanocarriers for Drug-Targeting Brain Tumors 587 622 .
Haiyan Wang, Yu Zhang, Xiaotao Xu & Aizhong Wang. (2021) An injectable mesoporous silica-based analgesic delivery system prolongs the duration of sciatic nerve block in mice with minimal toxicity. Acta Biomaterialia 135, pages 638-649.
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Natasha C. Brigham, Ru-Rong Ji & Matthew L. Becker. (2021) Degradable polymeric vehicles for postoperative pain management. Nature Communications 12:1.
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Yumiao He, Linan Qin, Yuguang Huang & Chao Ma. (2020) Advances of Nano-Structured Extended-Release Local Anesthetics. Nanoscale Research Letters 15:1.
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Lisa Rahnfeld & Paola Luciani. (2020) Injectable Lipid-Based Depot Formulations: Where Do We Stand?. Pharmaceutics 12:6, pages 567.
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Subashini Raman, Syed Mahmood & Azizur Rahman. (2020) A Review on Lipid- Polymer Hybrid Nanoparticles and Preparation with Recent Update. Materials Science Forum 981, pages 322-327.
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Mohamed Hamdi, Hend Mohamed Abdel-Bar, Enas Elmowafy, Khuloud T. Al-Jamal & Gehanne A. S. Awad. (2020) An integrated vitamin E-coated polymer hybrid nanoplatform: A lucrative option for an enhanced in vitro macrophage retention for an anti-hepatitis B therapeutic prospect. PLOS ONE 15:1, pages e0227231.
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Xiaoli Liu & Qianqian Zhao. (2019) Long-term anesthetic analgesic effects: Comparison of tetracaine loaded polymeric nanoparticles, solid lipid nanoparticles, and nanostructured lipid carriers in vitro and in vivo. Biomedicine & Pharmacotherapy 117, pages 109057.
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Sylwia Łukasiewicz, Antoni Mikołajczyk, Marta Szczęch, Krzysztof Szczepanowicz, Piotr Warszyński & Marta Dziedzicka-Wasylewska. (2019) Encapsulation of clozapine into polycaprolactone nanoparticles as a promising strategy of the novel nanoformulation of the active compound. Journal of Nanoparticle Research 21:7.
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