Advanced search
Publication Cover
International Journal of Nanomedicine Volume 14, 2019 - Issue
Submit an article Journal homepage
493
Views
149
CrossRef citations to date
0
Altmetric
Review

Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy

Faezeh Vakhshiteh1 Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, [email protected]
,
Fatemeh Atyabi1 Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, [email protected];2 Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, [email protected]Correspondence[email protected]
&
Seyed Nasser Ostad3 Department of Toxicology & Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
Pages 2847-2859 | Published online: 23 Apr 2019

Citations (149)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Emina Karahmet Sher, Azra Kalić, Amina Džidić-Krivić, Merima Beća- Zećo, Emma Pinjić & Farooq Sher. (2023) Cellular therapeutic potential of genetically engineered stem cells in cancer treatment. Biotechnology and Genetic Engineering Reviews 0:0, pages 1-36.
Read now
Hong Lv, Jing Yu, Hao Zhang, Xingjia Qian, Qian Wang, Bing Lu & Yifeng Sun. (2022) MicroRNA-631 deriving from bone marrow mesenchymal stem cell exosomes facilitates the malignant behavior of non-small cell lung cancer via modulating the E2F family of transcription factor 2/phosphatidylinositol 3‐kinase/Akt signaling pathway. Bioengineered 13:4, pages 8382-8395.
Read now
He Huang, Peilin Zhong, Jianxing Zhang, Xinghe Chen, Jinwen Chen, Tian Lin & Qiang Wu. (2022) Human umbilical cord-mesenchymal stem cells-derived exosomes carrying microRNA-15a-5p possess therapeutic effects on Wilms tumor via regulating septin 2. Bioengineered 13:3, pages 6136-6148.
Read now
Mohd Mughees, Krishna Kumar & Saima Wajid. (2021) Exosome vesicle as a nano-therapeutic carrier for breast cancer. Journal of Drug Targeting 29:2, pages 121-130.
Read now
Rong Xu, Yingying Bai, Shudan Min, Xiaoxuan Xu, Tianyu Tang & Shenghong Ju. (2020) In vivo Monitoring and Assessment of Exogenous Mesenchymal Stem Cell-Derived Exosomes in Mice with Ischemic Stroke by Molecular Imaging. International Journal of Nanomedicine 15, pages 9011-9023.
Read now
Qingqing Yin, Xiaojuan Ji, Renjun Lv, Jin-Jing Pei, Yifeng Du, Chao Shen & Xunyao Hou. (2020) Targetting Exosomes as a New Biomarker and Therapeutic Approach for Alzheimer’s Disease. Clinical Interventions in Aging 15, pages 195-205.
Read now

Articles from other publishers (143)

Disha N. Moholkar, Raghuram Kandimalla, Ramesh C. Gupta & Farrukh Aqil. (2023) Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes. Cancer Letters 565, pages 216220.
Crossref
Dovydas Gečys, Rūta Skredėnienė, Emilija Gečytė, Arūnas Kazlauskas, Ingrida Balnytė & Aistė Jekabsone. (2023) Adipose Tissue-Derived Stem Cell Extracellular Vesicles Suppress Glioblastoma Proliferation, Invasiveness and Angiogenesis. Cells 12:9, pages 1247.
Crossref
David J. Rademacher. (2023) Potential for Therapeutic-Loaded Exosomes to Ameliorate the Pathogenic Effects of α-Synuclein in Parkinson’s Disease. Biomedicines 11:4, pages 1187.
Crossref
Huichao Fu, Yunjiao Wu, Jianbai Chen, Xing Hu, Xiaoyan Wang & Gongping Xu. (2023) Exosomes and osteosarcoma drug resistance. Frontiers in Oncology 13.
Crossref
Xinyun Su, Akshaya Upadhyay, Simon D. Tran & Zhengmei Lin. (2023) Cell-Free Therapies: The Use of Cell Extracts to Mitigate Irradiation-Injured Salivary Glands. Biology 12:2, pages 305.
Crossref
Elena De Falco, Antonella Bordin, Cecilia Menna, Xhulio Dhori, Vittorio Picchio, Claudia Cozzolino, Elisabetta De Marinis, Erica Floris, Noemi Maria Giorgiano, Paolo Rosa, Erino Angelo Rendina, Mohsen Ibrahim & Antonella Calogero. (2023) Remote Adipose Tissue-Derived Stromal Cells of Patients with Lung Adenocarcinoma Generate a Similar Malignant Microenvironment of the Lung Stromal Counterpart. Journal of Oncology 2023, pages 1-15.
Crossref
Elham Oveili, Somayeh Vafaei, Haniyeh Bazavar, Yeganeh Eslami, Ehsan Mamaghanizadeh, Saman Yasamineh & Omid Gholizadeh. (2023) The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases. Cell Communication and Signaling 21:1.
Crossref
Hao Cai & Haidong Guo. (2023) Mesenchymal Stem Cells and Their Exocytotic Vesicles. International Journal of Molecular Sciences 24:3, pages 2085.
Crossref
David Schweer, Namrata Anand, Abigail Anderson, J. Robert McCorkle, Khaga Neupane, Alexandra N. Nail, Brock Harvey, Kristen S. Hill, Frederick Ueland, Christopher Richards & Jill Kolesar. (2023) Human macrophage-engineered vesicles for utilization in ovarian cancer treatment. Frontiers in Oncology 12.
Crossref
Aria Salehpour, Saule Balmagambetova, Nadiar Mussin, Asset Kaliyev & Farhad Rahmanifar. (2023) Mesenchymal stromal/stem cell-derived exosomes and genitourinary cancers: A mini review. Frontiers in Cell and Developmental Biology 10.
Crossref
Mengyuan Hou, Jingwu Li, Zhiwu Wang & Yankun Liu. 2023. Exosomes - Recent Advances From Bench to Bedside [Working Title]. Exosomes - Recent Advances From Bench to Bedside [Working Title].
Pouria Hajmomeni, Sajjad Sisakhtnezhad & Ali Bidmeshkipour. (2023) Thymoquinone-treated mouse mesenchymal stem cells-derived conditioned medium inhibits human breast cancer cells in vitro. Chemico-Biological Interactions 369, pages 110283.
Crossref
Manaswini Gattupalli, Parry Dey, Shanmugam Poovizhi, Riya Ben Patel, Debasish Mishra & Satarupa Banerjee. 2023. Regenerative Medicine. Regenerative Medicine 331 390 .
Prabhat Ranjan, Karen Colin, Roshan Kumar Dutta & Suresh Kumar Verma. (2022) Challenges and future scope of exosomes in the treatment of cardiovascular diseases. The Journal of Physiology.
Crossref
Ghader Babaei, Mehdi Asghari Vostakolaei, Masoumeh Rajabi Bazl, Shiva Gholizadeh-Ghaleh Aziz, Elham Gholipour & Kazem Nejati-Koshki. (2022) The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells. Life Sciences 310, pages 121103.
Crossref
Jenna Ollodart, Kelly F. Contino, Gagan Deep & Yusuke Shiozawa. (2022) The impacts of exosomes on bone metastatic progression and their potential clinical utility. Bone Reports 17, pages 101606.
Crossref
Houman Parsaei, Mir Javad Moosavifar, Mina Eftekharzadeh, Reihaneh Ramezani, Mahmood Barati, Soheil Mirzaei & Maliheh Nobakht. (2022) Exosomes to control glioblastoma multiforme: Investigating the effects of mesenchymal stem cell‐derived exosomes on C6 cells in vitro. Cell Biology International 46:12, pages 2028-2040.
Crossref
Safir Ullah Khan, Munir Ullah Khan, Yanyan Gao, Muhammad Imran Khan, Sabah Mushtaq Puswal, Muhammad Zubair, Muhammad Ammar Khan, Rahat Farwa, Shuang Gao, Rizwan Ali & Nazim Hussain. (2022) Unique therapeutic potentialities of exosomes based nanodrug carriers to target tumor microenvironment in cancer therapy. OpenNano 8, pages 100091.
Crossref
Babak Jahangiri, Mohammad Khalaj-Kondori, Elahe Asadollahi, Leyli Purrafee Dizaj & Majid Sadeghizadeh. (2022) MSC-Derived exosomes suppress colorectal cancer cell proliferation and metastasis via miR-100/mTOR/miR-143 pathway. International Journal of Pharmaceutics 627, pages 122214.
Crossref
Xiaowen Zhang, Xuejia Hou, Liu Te, Zhou Zhongsheng, Jinlan Jiang & Xiaodong Wu. (2022) Mesenchymal stem cells and exosomes improve cognitive function in the aging brain by promoting neurogenesis. Frontiers in Aging Neuroscience 14.
Crossref
Anna Słysz, Katarzyna Siennicka, Ewa Kijeńska-Gawrońska, Tomasz Dębski, Aleksandra Zołocińska, Wojciech Święszkowski & Zygmunt Pojda. (2022) The impact of electroconductive multifunctional composite nanofibrous scaffold on adipose-derived mesenchymal stem cells. Tissue and Cell 78, pages 101899.
Crossref
Ganesan Jothimani, Surajit Pathak, Suman Dutta, Asim K. Duttaroy & Antara Banerjee. (2022) A Comprehensive Cancer-Associated MicroRNA Expression Profiling and Proteomic Analysis of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes. Tissue Engineering and Regenerative Medicine 19:5, pages 1013-1031.
Crossref
Szeliski K, Drewa T & Pokrywczyńska M. (2022) Small extracellular vesicles as a multicomponent biomarker platform in urinary tract carcinomas. Frontiers in Molecular Biosciences 9.
Crossref
Jafar Rezaie, Maryam Feghhi & Tahereh Etemadi. (2022) A review on exosomes application in clinical trials: perspective, questions, and challenges. Cell Communication and Signaling 20:1.
Crossref
Amir Hossein Mansourabadi, Azin Aghamajidi, Fatemeh Faraji, Shirin Taghizadeh, Leila Mohamed Khosroshahi, Mona Bahramkiya & Maryam Azimi. (2022) Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line. BMC Molecular and Cell Biology 23:1.
Crossref
Xia Wang, Lu Tian, Jingyi Lu & Irene Oi-Lin Ng. (2022) Exosomes and cancer - Diagnostic and prognostic biomarkers and therapeutic vehicle. Oncogenesis 11:1.
Crossref
Zhengjun Lin, Yanlin Wu, Yiting Xu, Guoqing Li, Zhihong Li & Tang Liu. (2022) Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential. Molecular Cancer 21:1.
Crossref
Leila Moeinzadeh, Iman Razeghian-Jahromi, Zeinab Zarei-Behjani, Zohreh Bagheri & Mahboobeh Razmkhah. (2022) Composition, Biogenesis, and Role of Exosomes in Tumor Development. Stem Cells International 2022, pages 1-12.
Crossref
Jingqi Qi, Bingbing Wu, Xiuying Chen, Wei Wei & Xudong Yao. (2022) Diagnostic biomolecules and combination therapy for pre-eclampsia. Reproductive Biology and Endocrinology 20:1.
Crossref
Mohsen Karami fath, Mehran Anjomrooz, Seyed Reza Taha, Mahdieh Shariat Zadeh, Mahya Sahraei, Raihaneh Atbaei, Andarz Fazlollahpour naghibi, Zahra Payandeh, Zobeir Rahmani & Ghasem Barati. (2022) The therapeutic effect of exosomes from mesenchymal stem cells on colorectal cancer: Toward cell-free therapy. Pathology - Research and Practice 237, pages 154024.
Crossref
Tomoya Oishi, Masahiko Ito, Shinichiro Koizumi, Makoto Horikawa, Taisuke Yamamoto, Satoru Yamagishi, Tomohiro Yamasaki, Tetsuro Sameshima, Tetsuro Suzuki, Haruhiko Sugimura, Hiroki Namba & Kazuhiko Kurozumi. (2022) Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases. Molecular Therapy - Methods & Clinical Development 26, pages 253-265.
Crossref
Abhimanyu Thakur, Xiaoshan Ke, Ya-Wen Chen, Pedram Motallebnejad, Kui Zhang, Qizhou Lian & Huanhuan Joyce Chen. (2022) The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics. Protein & Cell 13:9, pages 631-654.
Crossref
Neha N Parayath, Srujan K Gandham & Mansoor M Amiji. (2022) Tumor-targeted miRNA nanomedicine for overcoming challenges in immunity and therapeutic resistance. Nanomedicine 17:19, pages 1355-1373.
Crossref
Ayaz M. Belkozhayev, Minnatallah Al-Yozbaki, Alex George, Raigul Ye Niyazova, Kamalidin O. Sharipov, Lee J. Byrne & Cornelia M. Wilson. (2022) Extracellular Vesicles, Stem Cells and the Role of miRNAs in Neurodegeneration. Current Neuropharmacology 20:8, pages 1450-1478.
Crossref
Yukang Lu, Lanfeng Wang, Mengting Zhang & Zhiping Chen. (2022) Mesenchymal Stem Cell-Derived Small Extracellular Vesicles: A Novel Approach for Kidney Disease Treatment. International Journal of Nanomedicine Volume 17, pages 3603-3618.
Crossref
Qiudan Zhang, Chenming Zhong, Jinze Shen, Sang Chen, Yunhua Jia & Shiwei Duan. (2022) Emerging role of LINC00461 in cancer. Biomedicine & Pharmacotherapy 152, pages 113239.
Crossref
Shiting Weng, Qi-Lun Lai, Junjun Wang, Liying Zhuang, Lin Cheng, Yejia Mo, Lu Liu, Zexian Zhao, Ying Zhang & Song Qiao. (2022) The Role of Exosomes as Mediators of Neuroinflammation in the Pathogenesis and Treatment of Alzheimer’s Disease. Frontiers in Aging Neuroscience 14.
Crossref
Jiacheng Lv, Shude Yang, Mengzhu Lv, Jiarui Lv, Yanan Sui & Shu Guo. (2022) Protective roles of mesenchymal stem cells on skin photoaging: A narrative review. Tissue and Cell 76, pages 101746.
Crossref
Shan Lu, Ruihan Wang, Weiguo Fu & Yi Si. (2022) Applications of Extracellular Vesicles in Abdominal Aortic Aneurysm. Frontiers in Cardiovascular Medicine 9.
Crossref
Shenyuan Chen, Fengtian Sun, Hui Qian, Wenrong Xu & Jiajia Jiang. (2022) Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell-Derived Exosomes in Cell-Free Therapy. Stem Cells International 2022, pages 1-18.
Crossref
Hanbo Ma, Fengyun Weng, Lang Wang, Xiaowen Tong, Yinan Yao & Huaifang Li. (2022) Extracellular vesicle-mediated delivery of miR-127-3p inhibits the proliferation and invasion of choriocarcinoma cells by targeting ITGA6. Experimental Cell Research 414:2, pages 113098.
Crossref
Tingwei Lu, Zhen Zhang, Jianjun Zhang, Xinhua Pan, Xueqin Zhu, Xu Wang, Zhihui Li, Min Ruan, Huasheng Li, Wantao Chen & Ming Yan. (2022) CD73 in small extracellular vesicles derived from HNSCC defines tumour‐associated immunosuppression mediated by macrophages in the microenvironment. Journal of Extracellular Vesicles 11:5.
Crossref
Chen Hu, Qiang Huang & Qing Sun. (2022) The Regulation of Lymph Node Pre-Metastatic Niche Formation in Head and Neck Squamous Cell Carcinoma. Frontiers in Oncology 12.
Crossref
Min Heui Yoo, A-Ram Lee & Kyoung-Sik Moon. (2022) Characteristics of Extracellular Vesicles and Preclinical Testing Considerations Prior to Clinical Applications. Biomedicines 10:4, pages 869.
Crossref
Yiling Guo, Yujia Zhai, Longyuan Wu, Yazhuo Wang, Puzhen Wu & Lixia Xiong. (2022) Mesenchymal Stem Cell-Derived Extracellular Vesicles: Pleiotropic Impacts on Breast Cancer Occurrence, Development, and Therapy. International Journal of Molecular Sciences 23:6, pages 2927.
Crossref
Panpan Liu, Qun Zhang, Jun Mi, Shuangshuang Wang, Qiuping Xu, Dexuan Zhuang, Wenqian Chen, Chang Liu, Liwei Zhang, Jing Guo & Xunwei Wu. (2022) Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246. Stem Cell Research & Therapy 13:1.
Crossref
Tomasz Adamus, Chia-Yang Hung, Chunsong Yu, Elaine Kang, Mohamed Hammad, Linda Flores, Sergey Nechaev, Qifang Zhang, Joanna Marie Gonzaga, Kokilah Muthaiyah, Piotr Swiderski, Karen S. Aboody & Marcin Kortylewski. (2022) Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells. Molecular Therapy - Nucleic Acids 27, pages 611-620.
Crossref
Maryam Yousefi Dehbidi, Nima Goodarzi, Mohammad H. Azhdari & Mohammad Doroudian. (2021) Mesenchymal stem cells and their derived exosomes to combat Covid–19. Reviews in Medical Virology 32:2.
Crossref
Julika HuberMichelle F. GriffinMichael T. LongakerNatalina Quarto. (2022) Exosomes: A Tool for Bone Tissue Engineering. Tissue Engineering Part B: Reviews 28:1, pages 101-113.
Crossref
Sirine Yassine & Nada Alaaeddine. (2021) Mesenchymal Stem Cell Exosomes and Cancer: Controversies and Prospects. Advanced Biology 6:2.
Crossref
Jitrada Phetfong, Tulyapruek Tawonsawatruk, Witchayapon Kamprom, Pawared Ontong, Dalina Tanyong, Suparerk Borwornpinyo & Aungkura Supokawej. (2021) Bone marrow‐mesenchymal stem cell‐derived extracellular vesicles affect proliferation and apoptosis of leukemia cells in vitro . FEBS Open Bio 12:2, pages 470-479.
Crossref
Shuang Li & Limin Chen. (2022) Exosomes in Pathogenesis, Diagnosis, and Treatment of Hepatocellular Carcinoma. Frontiers in Oncology 12.
Crossref
Benshuai You, Can Jin, Jiaxin Zhang, Min Xu, Wenrong Xu, Zixuan Sun & Hui Qian. (2022) MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation. Stem Cells International 2022, pages 1-12.
Crossref
Jie Yang & Liman Zhang. (2022) The roles and therapeutic approaches of MSC-derived exosomes in colorectal cancer. Clinical and Translational Oncology 24:6, pages 959-967.
Crossref
Mehdi Najar, Rahma Melki, Ferial Khalife, Laurence Lagneaux, Fatima Bouhtit, Douaa Moussa Agha, Hassan Fahmi, Philippe Lewalle, Mohammad Fayyad-Kazan & Makram Merimi. (2022) Therapeutic Mesenchymal Stem/Stromal Cells: Value, Challenges and Optimization. Frontiers in Cell and Developmental Biology 9.
Crossref
Hojun Choi, Hwayoung Yim, Cheolhyoung Park, So-Hee Ahn, Yura Ahn, Areum Lee, Heekyoung Yang & Chulhee Choi. (2022) Targeted Delivery of Exosomes Armed with Anti-Cancer Therapeutics. Membranes 12:1, pages 85.
Crossref
Jacopo Meldolesi. (2022) Cancer Stem Cells and Their Vesicles, Together with Other Stem and Non-Stem Cells, Govern Critical Cancer Processes: Perspectives for Medical Development. International Journal of Molecular Sciences 23:2, pages 625.
Crossref
Xiaolan Wu, Shanshan Jin, Chengye Ding, Yu Wang, Danqing He & Yan Liu. (2022) Mesenchymal Stem Cell-Derived Exosome Therapy of Microbial Diseases: From Bench to Bed. Frontiers in Microbiology 12.
Crossref
Hongmei Liu, Shichen Deng, Lu Han, Yan Ren, Jian Gu, Lili He, Tianqing Liu & Zhi-xiang Yuan. (2022) Mesenchymal stem cells, exosomes and exosome-mimics as smart drug carriers for targeted cancer therapy. Colloids and Surfaces B: Biointerfaces 209, pages 112163.
Crossref
Jonathan M. Carnino & Heedoo Lee. 2022. 105 127 .
Dinesh Kumar, Maria Ishaque & Pawan Kumar Raghav. 2022. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 2063 2077 .
Dinesh Kumar, Maria Ishaque & Pawan Kumar Raghav. 2021. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 1 15 .
Marcella Liciani Franco, Stephany Beyerstedt & Érika Bevilaqua Rangel. (2021) Klotho and Mesenchymal Stem Cells: A Review on Cell and Gene Therapy for Chronic Kidney Disease and Acute Kidney Disease. Pharmaceutics 14:1, pages 11.
Crossref
Leila Taghizadeh Momen, Arash Abdolmaleki, Asadollah Asadi & Muhammad Akram. (2021) Regeneration and Diagnosis of Kidney Disease Using Exosomes. Jentashapir Journal of Cellular and Molecular Biology 12:4.
Crossref
Hao Zhou, Xiaoyun He, Yuxiang He, Chunlin Ou & Pengfei Cao. (2021) Exosomal circRNAs: Emerging Players in Tumor Metastasis. Frontiers in Cell and Developmental Biology 9.
Crossref
Tianxin Lyu, Yinuo Wang, Ding Li, Hui Yang, Bin Qin, Wenli Zhang, Zhiyue Li, Cheng Cheng, Binglei Zhang, Rongqun Guo & Yongping Song. (2021) Exosomes from BM-MSCs promote acute myeloid leukemia cell proliferation, invasion and chemoresistance via upregulation of S100A4. Experimental Hematology & Oncology 10:1.
Crossref
Jana Janockova, Lucia Slovinska, Denisa Harvanova, Timea Spakova & Jan Rosocha. (2021) New therapeutic approaches of mesenchymal stem cells-derived exosomes. Journal of Biomedical Science 28:1.
Crossref
Yixuan Ding, Wentong Mei, Zhi Zheng, Feng Cao, Kuo Liang, Yuchen Jia, Yuting Wang, Dachuan Liu, Jia Li & Fei Li. (2021) Exosomes secreted from human umbilical cord mesenchymal stem cells promote pancreatic ductal adenocarcinoma growth by transferring miR-100-5p. Tissue and Cell 73, pages 101623.
Crossref
Nadia Sadanandan, Alex Shear, Beverly Brooks, Madeline Saft, Dorothy Anne Galang Cabantan, Chase Kingsbury, Henry Zhang, Stefan Anthony, Zhen-Jie Wang, Felipe Esparza Salazar, Alma R. Lezama Toledo, Germán Rivera Monroy, Joaquin Vega Gonzales-Portillo, Alexa Moscatello, Jea-Young Lee & Cesario V. Borlongan. (2021) Treating Metastatic Brain Cancers With Stem Cells. Frontiers in Molecular Neuroscience 14.
Crossref
Michela Saviana, Giulia Romano, Patricia Le, Mario Acunzo & Patrick Nana-Sinkam. (2021) Extracellular Vesicles in Lung Cancer Metastasis and Their Clinical Applications. Cancers 13:22, pages 5633.
Crossref
Komal Abhange, Amy Makler, Yi Wen, Natasha Ramnauth, Wenjun Mao, Waseem Asghar & Yuan Wan. (2021) Small extracellular vesicles in cancer. Bioactive Materials 6:11, pages 3705-3743.
Crossref
Hao Gu, Chao Yan, Haijun Wan, Lin Wu, Junjie Liu, Zhiqiang Zhu & Dazhi Gao. (2021) Mesenchymal stem cell-derived exosomes block malignant behaviors of hepatocellular carcinoma stem cells through a lncRNA C5orf66-AS1/microRNA-127-3p/DUSP1/ERK axis. Human Cell 34:6, pages 1812-1829.
Crossref
Anh Duy Do, Ida Kurniawati, Chia-Ling Hsieh, Tai-Tong Wong, Yu-Ling Lin & Shian-Ying Sung. (2021) Application of Mesenchymal Stem Cells in Targeted Delivery to the Brain: Potential and Challenges of the Extracellular Vesicle-Based Approach for Brain Tumor Treatment. International Journal of Molecular Sciences 22:20, pages 11187.
Crossref
Jessica Dörnen & Thomas Dittmar. (2021) The Role of MSCs and Cell Fusion in Tissue Regeneration. International Journal of Molecular Sciences 22:20, pages 10980.
Crossref
Linxian Zhao, Kai Zhang, Hongyu He, Yongping Yang, Wei Li, Tongjun Liu & Jiannan Li. (2021) The Relationship Between Mesenchymal Stem Cells and Tumor Dormancy. Frontiers in Cell and Developmental Biology 9.
Crossref
Min Shen & Tong Chen. (2021) Mesenchymal Stem Cell-Derived Exosomes and Their Potential Agents in Hematological Diseases. Oxidative Medicine and Cellular Longevity 2021, pages 1-13.
Crossref
Faezeh Vakhshiteh, Shokoufeh Hassani, Navid Momenifar & Fatemeh Pakdaman. (2021) Exosomal circRNAs: new players in colorectal cancer. Cancer Cell International 21:1.
Crossref
Akira Yokoi & Takahiro Ochiya. (2021) Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology. Seminars in Cancer Biology 74, pages 79-91.
Crossref
Yi-Hsuan Ou, Jeremy Liang, Bertrand Czarny, Matthias G. Wacker, Victor Yu, Jiong-Wei Wang & Giorgia Pastorin. (2021) Extracellular Vesicle (EV) biohybrid systems for cancer therapy: Recent advances and future perspectives. Seminars in Cancer Biology 74, pages 45-61.
Crossref
Shabirul Haque, Pooja Swami & Azhar Khan. (2021) S. Typhi derived vaccines and a proposal for outer membrane vesicles (OMVs) as potential vaccine for typhoid fever. Microbial Pathogenesis 158, pages 105082.
Crossref
Wen‐Jie Gu, Yi‐Wen Shen, Li‐Jun Zhang, Hong Zhang, Dale G. Nagle, Xin Luan & San‐Hong Liu. (2021) The multifaceted involvement of exosomes in tumor progression: Induction and inhibition. MedComm 2:3, pages 297-314.
Crossref
Yu-Shui Ma, Ji-Bin Liu, Lan Lin, Hui Zhang, Jian-Jun Wu, Yi Shi, Cheng-You Jia, Dan-Dan Zhang, Fei Yu, Hui-Min Wang, Yu-Zhen Yin, Xiao-Hui Jiang, Pei-Yao Wang, Lin-Lin Tian, Ping-Sheng Cao, Xu-Ming Wu, Hai-Min Lu, Li-Peng Gu, Jia-Jia Zhang, Gu-Jun Cong, Pei Luo, Xiao-Ming Zhong, Bo Cai, Min-Xin Shi, Su-Qing Zhang, Liu Li, Wen-Jie Zhang, Yu Liu, Zhi-Zhen Li, Ting-Miao Wu, Zhi-Jun Wu, Gao-Ren Wang, Zhong-Wei Lv, Chang-Chun Ling, Kai-Jian Chu & Da Fu. (2021) Exosomal microRNA-15a from mesenchymal stem cells impedes hepatocellular carcinoma progression via downregulation of SALL4. Cell Death Discovery 7:1.
Crossref
Can Jin, Peipei Wu, Linli Li, Wenrong Xu & Hui Qian. (2021) Exosomes: Emerging Therapy Delivery Tools and Biomarkers for Kidney Diseases. Stem Cells International 2021, pages 1-18.
Crossref
Zhengyi Ruan, Lili Lu, Li Zhang & Min Dong. (2020) Bone marrow stromal cells-derived microRNA-181-containing extracellular vesicles inhibit ovarian cancer cell chemoresistance by downregulating MEST via the Wnt/β-catenin signaling pathway. Cancer Gene Therapy 28:7-8, pages 785-798.
Crossref
Hojun Choi, Yoorim Choi, Hwa Young Yim, Amin Mirzaaghasi, Jae-Kwang Yoo & Chulhee Choi. (2021) Biodistribution of Exosomes and Engineering Strategies for Targeted Delivery of Therapeutic Exosomes. Tissue Engineering and Regenerative Medicine 18:4, pages 499-511.
Crossref
Lacy E. Lowry, Maryanne C. Herzig, Barbara A. Christy, Richard Schäfer, Shibani Pati, Andrew P. Cap & James A. Bynum. (2021) Neglected No More: Emerging Cellular Therapies in Traumatic Injury. Stem Cell Reviews and Reports 17:4, pages 1194-1214.
Crossref
Mengdong Liu, Yunshu Yang, Bin Zhao, Yuefan Yang, Jing Wang, Kuo Shen, Xuekang Yang, Dahai Hu, Guoxu Zheng & Juntao Han. (2021) Exosomes Derived From Adipose-Derived Mesenchymal Stem Cells Ameliorate Radiation-Induced Brain Injury by Activating the SIRT1 Pathway. Frontiers in Cell and Developmental Biology 9.
Crossref
Bryan Falcones, Héctor Sanz-Fraile, Esther Marhuenda, Irene Mendizábal, Ignacio Cabrera-Aguilera, Nanthilde Malandain, Juan J. Uriarte, Isaac Almendros, Daniel Navajas, Daniel J. Weiss, Ramon Farré & Jorge Otero. (2021) Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells. Polymers 13:14, pages 2350.
Crossref
Dima Hattab, Amirah Mohd Gazzali & Athirah Bakhtiar. (2021) Clinical Advances of siRNA-Based Nanotherapeutics for Cancer Treatment. Pharmaceutics 13:7, pages 1009.
Crossref
Pawan Kumar Raghav & Zoya Mann. (2021) Cancer stem cells targets and combined therapies to prevent cancer recurrence. Life Sciences 277, pages 119465.
Crossref
Feng Hu, Jixuan Liu, Huibo Liu, Fan Li, Minjie Wan, Manli Zhang, Yanfang Jiang & Min Rao. (2021) Role of Exosomal Non-coding RNAs in Gastric Cancer: Biological Functions and Potential Clinical Applications. Frontiers in Oncology 11.
Crossref
Yichao Wang, Pan Wang, Lei Zhao, Xiaoying Chen, Zhu Lin, Ling Zhang & Zhaoyun Li. (2021) miR-224-5p Carried by Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes Regulates Autophagy in Breast Cancer Cells via HOXA5. Frontiers in Cell and Developmental Biology 9.
Crossref
Ali Hassanzadeh, Heshu Sulaiman Rahman, Alexander Markov, Judi Januadi Endjun, Angelina Olegovna Zekiy, Max Stanley Chartrand, Nasrin Beheshtkhoo, Mohammad Amin Jadidi Kouhbanani, Faroogh Marofi, Marzieh Nikoo & Mostafa Jarahian. (2021) Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities. Stem Cell Research & Therapy 12:1.
Crossref
Xu Zhang, Hongbo Zhang, Jianmei Gu, Jiayin Zhang, Hui Shi, Hui Qian, Dongqing Wang, Wenrong Xu, Jianming Pan & Hélder A. Santos. (2021) Engineered Extracellular Vesicles for Cancer Therapy. Advanced Materials 33:14.
Crossref
Natalia Georgantzoglou, Alexandros Pergaris, Christos Masaoutis & Stamatios Theocharis. (2021) Extracellular Vesicles as Biomarkers Carriers in Bladder Cancer: Diagnosis, Surveillance, and Treatment. International Journal of Molecular Sciences 22:5, pages 2744.
Crossref
Byung-Chul Lee, Insung Kang & Kyung-Rok Yu. (2021) Therapeutic Features and Updated Clinical Trials of Mesenchymal Stem Cell (MSC)-Derived Exosomes. Journal of Clinical Medicine 10:4, pages 711.
Crossref
Chia-Chu Hsieh, Szu-Chun Hsu, Ming Yao & Dong-Ming Huang. (2021) CD9 Upregulation-Decreased CCL21 Secretion in Mesenchymal Stem Cells Reduces Cancer Cell Migration. International Journal of Molecular Sciences 22:4, pages 1738.
Crossref
Weizong Wang, Yixin Zhao, Huilin Li, Yujiao Zhang, Xiaomeng Jia, Cong Wang, Pengju Zhu, Jiangrong Wang & Yinglong Hou. (2021) Exosomes secreted from mesenchymal stem cells mediate the regeneration of endothelial cells treated with rapamycin by delivering pro-angiogenic microRNAs. Experimental Cell Research 399:1, pages 112449.
Crossref
Faezeh Vakhshiteh, Soheila Rahmani, Seyed Nasser Ostad, Zahra Madjd, Rassoul Dinarvand & Fatemeh Atyabi. (2021) Exosomes derived from miR-34a-overexpressing mesenchymal stem cells inhibit in vitro tumor growth: A new approach for drug delivery. Life Sciences 266, pages 118871.
Crossref
Tianjiao Geng, Patrick Pan, Euphemia Leung, Qi Chen, Larry Chamley & Zimei Wu. (2021) Recent Advancement and Technical Challenges in Developing Small Extracellular Vesicles for Cancer Drug Delivery. Pharmaceutical Research 38:2, pages 179-197.
Crossref
Hoda ElkhenanyShilpi GuptaMostafa F. Abdelhai. (2021) Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review. International Journal of Coronaviruses 2:3, pages 23-37.
Crossref
Yaya Tang, Yan Zhou & Hong-Jun Li. (2021) Advances in mesenchymal stem cell exosomes: a review. Stem Cell Research & Therapy 12:1.
Crossref
Pei-Chin Chen, Yung-Che Kuo, Cheng-Ming Chuong & Yen-Hua Huang. (2021) Niche Modulation of IGF-1R Signaling: Its Role in Stem Cell Pluripotency, Cancer Reprogramming, and Therapeutic Applications. Frontiers in Cell and Developmental Biology 8.
Crossref
Leila Gholami, Vajihe Taghdiri Nooshabadi, Shiva Shahabi, Marzieh Jazayeri, Rana Tarzemany, Zohreh Afsartala & Khatereh Khorsandi. (2021) Extracellular vesicles in bone and periodontal regeneration: current and potential therapeutic applications. Cell & Bioscience 11:1.
Crossref
Dejene Tolossa Debela, Seke GY Muzazu, Kidist Digamo Heraro, Maureen Tayamika Ndalama, Betelhiem Woldemedhin Mesele, Dagimawi Chilot Haile, Sophia Khalayi Kitui & Tsegahun Manyazewal. (2021) New approaches and procedures for cancer treatment: Current perspectives. SAGE Open Medicine 9, pages 205031212110343.
Crossref
Aida Rezaei Nejad, Amir Ali Hamidieh, Mohammad Amir Amirkhani & Mahsa Mollapour Sisakht. (2021) Update review on five top clinical applications of human amniotic membrane in regenerative medicine. Placenta 103, pages 104-119.
Crossref
Adegbenro Omotuyi John Fakoya, Iziegbe Fenemigho, Chisom Valentine Asuzu, Ewaenosa Esohe Ukponmwan, Kingsley Chinonyerem Nnawuba & Khawaja Husnain Haider. 2021. Stem Cells. Stem Cells 93 118 .
Mrinal K. Das, Taral R. Lunavat, Hrvoje Miletic & Jubayer A. Hossain. 2021. Cell Biology and Translational Medicine, Volume 12. Cell Biology and Translational Medicine, Volume 12 139 157 .
Dana Lengel, Cruz Sevilla, Zoe L. Romm, Jimmy W. Huh & Ramesh Raghupathi. (2020) Stem Cell Therapy for Pediatric Traumatic Brain Injury. Frontiers in Neurology 11.
Crossref
Natalia L. Klyachko, Camryn J. Arzt, Samuel M. Li, Olesia A. Gololobova & Elena V. Batrakova. (2020) Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations. Pharmaceutics 12:12, pages 1171.
Crossref
Yuan Liang, Dalin Zhang, Linlin Li, Tian Xin, Yuwei Zhao, Rui Ma & Jiang Du. (2020) Exosomal microRNA-144 from bone marrow-derived mesenchymal stem cells inhibits the progression of non-small cell lung cancer by targeting CCNE1 and CCNE2. Stem Cell Research & Therapy 11:1.
Crossref
Mahdi Ahmadi & Jafar Rezaie. (2020) Tumor cells derived-exosomes as angiogenenic agents: possible therapeutic implications. Journal of Translational Medicine 18:1.
Crossref
Haizhou Xing, Chunyan Liang, Xintong Xu, Hui Sun, Xiaojun Ma & Zhongxing Jiang. (2020) Mesenchymal stroma/stem‐like cells of GARP knockdown inhibits cell proliferation and invasion of mouse colon cancer cells (MC38) through exosomes. Journal of Cellular and Molecular Medicine 24:23, pages 13984-13990.
Crossref
Hongtao Xu, Chien-Wei Lee, Yu-Fan Wang, Shuting Huang, Lih-Ying Shin, Yu-Hsuan Wang, Zihao Wan, Xiaobo Zhu, Patrick Shu Hang Yung & Oscar Kuang-Sheng Lee. (2020) The Role of Paracrine Regulation of Mesenchymal Stem Cells in the Crosstalk With Macrophages in Musculoskeletal Diseases: A Systematic Review. Frontiers in Bioengineering and Biotechnology 8.
Crossref
June Seok Heo, Ja-Yun Lim, Dae Wui Yoon, Sangshin Pyo & Jinkwan Kim. (2020) Exosome and Melatonin Additively Attenuates Inflammation by Transferring miR-34a, miR-124, and miR-135b. BioMed Research International 2020, pages 1-9.
Crossref
Vuong Cat KhanhMizuho FukushigeKana MoriguchiToshiharu YamashitaMotoo OsakaYuji HiramatsuOsamu Ohneda. (2020) Type 2 Diabetes Mellitus Induced Paracrine Effects on Breast Cancer Metastasis Through Extracellular Vesicles Derived from Human Mesenchymal Stem Cells. Stem Cells and Development 29:21, pages 1382-1394.
Crossref
Adriana Bajetto, Stefano Thellung, Irene Dellacasagrande, Aldo Pagano, Federica Barbieri & Tullio Florio. (2020) Cross talk between mesenchymal and glioblastoma stem cells: Communication beyond controversies. Stem Cells Translational Medicine 9:11, pages 1310-1330.
Crossref
Catharina Melzer, Juliane von der Ohe & Ralf Hass. (2020) Anti-Tumor Effects of Exosomes Derived from Drug-Incubated Permanently Growing Human MSC. International Journal of Molecular Sciences 21:19, pages 7311.
Crossref
Dima Hattab & Athirah Bakhtiar. (2020) Bioengineered siRNA-Based Nanoplatforms Targeting Molecular Signaling Pathways for the Treatment of Triple Negative Breast Cancer: Preclinical and Clinical Advancements. Pharmaceutics 12:10, pages 929.
Crossref
Giulia Golinelli, Ilenia Mastrolia, Beatrice Aramini, Valentina Masciale, Massimo Pinelli, Lucrezia Pacchioni, Giulia Casari, Massimiliano Dall’Ora, Milena Botelho Pereira Soares, Patrícia Kauanna Fonseca Damasceno, Daniela Nascimento Silva, Massimo Dominici & Giulia Grisendi. (2020) Arming Mesenchymal Stromal/Stem Cells Against Cancer: Has the Time Come?. Frontiers in Pharmacology 11.
Crossref
Alessia Brossa, Valentina Fonsato, Cristina Grange, Stefania Tritta, Marta Tapparo, Ruggero Calvetti, Massimo Cedrino, Sofia Fallo, Paolo Gontero, Giovanni Camussi & Benedetta Bussolati. (2020) Extracellular vesicles from human liver stem cells inhibit renal cancer stem cell‐derived tumor growth in vitro and in vivo . International Journal of Cancer 147:6, pages 1694-1706.
Crossref
Hosanna Brave & Ronan MacLoughlin. (2020) State of the Art Review of Cell Therapy in the Treatment of Lung Disease, and the Potential for Aerosol Delivery. International Journal of Molecular Sciences 21:17, pages 6435.
Crossref
Hameeda Sultana & Girish Neelakanta. (2020) Arthropod exosomes as bubbles with message(s) to transmit vector-borne diseases. Current Opinion in Insect Science 40, pages 39-47.
Crossref
Chengyan Chu, Yue Gao, Xiaoyan Lan, Jianwen Lin, Aline M. Thomas & Shen Li. (2020) Stem-Cell Therapy as a Potential Strategy for Radiation-Induced Brain Injury. Stem Cell Reviews and Reports 16:4, pages 639-649.
Crossref
Maria Raffaella Zocchi, Francesca Tosetti, Roberto Benelli & Alessandro Poggi. (2020) Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy. Cancers 12:7, pages 1886.
Crossref
Xiaohong Gu, Yuechun Li, Kaixin Chen, Xingang Wang, Zhongyu Wang, Hao Lian, Yuanzheng Lin, Xing Rong, Maoping Chu, Jiafeng Lin & Xiaoling Guo. (2020) Exosomes derived from umbilical cord mesenchymal stem cells alleviate viral myocarditis through activating AMPK/mTOR‐mediated autophagy flux pathway. Journal of Cellular and Molecular Medicine 24:13, pages 7515-7530.
Crossref
Kiran Kuruvinashetti, S. Pakkiriswami & M. Packirisamy. (2020) Algal Extracellular Vesicles for Therapeutic Applications. Algal Extracellular Vesicles for Therapeutic Applications.
Joshua Holtzman & Heedoo Lee. (2020) Emerging role of extracellular vesicles in the respiratory system. Experimental & Molecular Medicine 52:6, pages 887-895.
Crossref
Faezeh Vakhshiteh, Ehsan Khabazian, Fatemeh Atyabi, Seyed Nasser Ostad, Zahra Madjd & Rassoul Dinarvand. (2020) Peptide-conjugated liposomes for targeted miR-34a delivery to suppress breast cancer and cancer stem-like population. Journal of Drug Delivery Science and Technology 57, pages 101687.
Crossref
Vadims Parfejevs, Krizia Sagini, Arturs Buss, Kristine Sobolevska, Alicia Llorente, Una Riekstina & Arturs Abols. (2020) Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges. Cells 9:5, pages 1171.
Crossref
Dae Hyun Ha, Hyun-keun Kim, Joon Lee, Hyuck Hoon Kwon, Gyeong-Hun Park, Steve Hoseong Yang, Jae Yoon Jung, Hosung Choi, Jun Ho Lee, Sumi Sung, Yong Weon Yi & Byong Seung Cho. (2020) Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration. Cells 9:5, pages 1157.
Crossref
S. Suvakov, C. Richards, V. Nikolic, T. Simic, K. McGrath, A. Krasnodembskaya & L. McClements. (2020) Emerging Therapeutic Potential of Mesenchymal Stem/Stromal Cells in Preeclampsia. Current Hypertension Reports 22:5.
Crossref
Masoumeh Einabadi, Jafar Ai, Mohammad Kargar, Farshid Kafilzadeh, Vajihe Taghdiri Nooshabadi & Houshang Jamali. (2020) Mesenchymal Cell-Derived Exosomes as Novel Useful Candidates for Drug Delivery. Archives of Neuroscience 7:2.
Crossref
Austin Gowen, Farah Shahjin, Subhash Chand, Katherine E. Odegaard & Sowmya V. Yelamanchili. (2020) Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications. Frontiers in Cell and Developmental Biology 8.
Crossref
Dinh-Toi Chu, Tiep Tien Nguyen, Nguyen Le Bao Tien, Dang-Khoa Tran, Jee-Heon Jeong, Pham Gia Anh, Vo Van Thanh, Dang Tien Truong & Thien Chu Dinh. (2020) Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications. Cells 9:3, pages 563.
Crossref
Paz de la Torre, María Jesús Pérez-Lorenzo, Álvaro Alcázar-Garrido & Ana I. Flores. (2020) Cell-Based Nanoparticles Delivery Systems for Targeted Cancer Therapy: Lessons from Anti-Angiogenesis Treatments. Molecules 25:3, pages 715.
Crossref
Hossein Abbaszadeh, Farzaneh Ghorbani, Mehdi Derakhshani, Aliakbar Movassaghpour & Mehdi Yousefi. (2019) Human umbilical cord mesenchymal stem cell‐derived extracellular vesicles: A novel therapeutic paradigm. Journal of Cellular Physiology 235:2, pages 706-717.
Crossref
Joanna Lelek & Ewa K. Zuba-Surma. (2020) Perspectives for Future Use of Extracellular Vesicles from Umbilical Cord- and Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells in Regenerative Therapies—Synthetic Review. International Journal of Molecular Sciences 21:3, pages 799.
Crossref
Ammar Ebrahimi, Pejman Abbasi & Magali Cucchiarini. (2020) Exploring the Role of Stem Cells in Cancer Development and Progression. Annals of Cancer Research and Therapy 28:1, pages 3-8.
Crossref
Sorina Dinescu, Alexandra Dobranici, Ramona Tecucianu, Aida Selaru, Roxana Balahura, Simona Ignat & Marieta Costache. 2021. Cell Biology and Translational Medicine, Volume 11. Cell Biology and Translational Medicine, Volume 11 139 163 .
Mercedes Herrera, Cristina Galindo-Pumariño, Vanesa García-Barberán & Cristina Peña. (2019) A Snapshot of The Tumor Microenvironment in Colorectal Cancer: The Liquid Biopsy. International Journal of Molecular Sciences 20:23, pages 6016.
Crossref
Wei Zhao, Pan Qin, Da Zhang, Xichun Cui, Jing Gao, Zhenzhu Yu, Yuting Chai, Jiaxiang Wang & Juan Li. (2019) Long non-coding RNA PVT1 encapsulated in bone marrow mesenchymal stem cell-derived exosomes promotes osteosarcoma growth and metastasis by stabilizing ERG and sponging miR-183-5p. Aging 11:21, pages 9581-9596.
Crossref
N. V. Bogatcheva & M. E. Coleman. (2019) Conditioned Medium of Mesenchymal Stromal Cells: A New Class of Therapeutics. Biochemistry (Moscow) 84:11, pages 1375-1389.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.