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Original Research

Biological evaluation of 5-fluorouracil nanoparticles for cancer chemotherapy and its dependence on the carrier, PLGA

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Pages 1685-1697 | Published online: 17 Aug 2011

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A. Hudita, I. C. Radu, B. Galateanu, O. Ginghina, H. Herman, C. Balta, M. Rosu, C. Zaharia, M. Costache, E. Tanasa, K. Velonia, A. Tsatsakis & A. Hermenean. (2021) Bioinspired silk fibroin nano-delivery systems protect against 5-FU induced gastrointestinal mucositis in a mouse model and display antitumor effects on HT-29 colorectal cancer cells in vitro. Nanotoxicology 15:7, pages 973-994.
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Abdelkader E Ashour, Mohammad Badran, Ashok Kumar, Tajamul Hussain, Ibrahim A Alsarra & Alaa Eldeen B Yassin. (2019) Physical PEGylation Enhances The Cytotoxicity Of 5-Fluorouracil-Loaded PLGA And PCL Nanoparticles. International Journal of Nanomedicine 14, pages 9259-9273.
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Articles from other publishers (11)

Aseel Kamil Mohammad Al-Mosawi, Ahmad Reza Bahrami, Sirous Nekooei, Amir Sh. Saljooghi & Maryam M. Matin. (2023) Using magnetic mesoporous silica nanoparticles armed with EpCAM aptamer as an efficient platform for specific delivery of 5-fluorouracil to colorectal cancer cells. Frontiers in Bioengineering and Biotechnology 10.
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Mohammed S. Saddik, Mahmoud M. A. Elsayed, Mohamed Salaheldin A. Abdelkader, Mohamed A. El-Mokhtar, Jelan A. Abdel-Aleem, Ahmed M. Abu-Dief, Mostafa F. Al-Hakkani, Hatem S. Farghaly & Heba A. Abou-Taleb. (2021) Novel Green Biosynthesis of 5-Fluorouracil Chromium Nanoparticles Using Harpullia pendula Extract for Treatment of Colorectal Cancer. Pharmaceutics 13:2, pages 226.
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Shivendu Ranjan, Nandita Dasgupta, Debasish Mishra & Chidambaram Ramalingam. (2020) Involvement of Bcl-2 Activation and G1 Cell Cycle Arrest in Colon Cancer Cells Induced by Titanium Dioxide Nanoparticles Synthesized by Microwave-Assisted Hybrid Approach. Frontiers in Bioengineering and Biotechnology 8.
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Debbie K. Ledezma, Preethi B. Balakrishnan, Juliana Cano-Mejia, Elizabeth E. Sweeney, Melissa Hadley, Catherine M. Bollard, Alejandro Villagra & Rohan Fernandes. (2020) Indocyanine Green-Nexturastat A-PLGA Nanoparticles Combine Photothermal and Epigenetic Therapy for Melanoma. Nanomaterials 10:1, pages 161.
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Po-Chung Chen, Doris Yii, Hsieh-Chih Tsai, Vijaya Rohini Parasuraman, Adhimoorthy Prasannan, Chen-Yu Kao & Juin-Yih Lai. (2019) Fabrication of branched polyethylenimin/alginic acid/poly(cyclohexane-1,4-diyl acetone dimethylene ketal as a nano size carrier for controlled release of 5-fluorouracil. Reactive and Functional Polymers 145, pages 104238.
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María del Carmen Sánchez-Navarro, Claudio Adrian Ruiz-Torres, Nereyda Niño-Martínez, Roberto Sánchez-Sánchez, Gabriel Alejandro Martínez-Castañón, I. DeAlba-Montero & Facundo Ruiz. (2018) Cytotoxic and Bactericidal Effect of Silver Nanoparticles Obtained by Green Synthesis Method Using Annona muricata Aqueous Extract and Functionalized with 5-Fluorouracil . Bioinorganic Chemistry and Applications 2018, pages 1-8.
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Chiranjib Chakraborty, Ashish Ranjan Sharma, Garima Sharma, Bimal Kumar Sarkar & Sang-Soo Lee. (2018) The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer. Oncotarget 9:11, pages 10164-10174.
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Jiaying Liu, Pallab Pradhan & Krishnendu Roy. 2016. Nanomaterials in Pharmacology. Nanomaterials in Pharmacology 413 438 .
Yu Ling Fan, Bing Yu Fan, Qiang Li, Shuang Leng & Li Hua Ma. (2013) A Novel 5-Fluorouracil-Loaded Polyelectrolyte Nanoparticle Formulation. Advanced Materials Research 690-693, pages 518-522.
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Tianzhi Yang, Divine Nyiawung, Alexandra Silber, Jiukuan Hao, Leanne Lai & Shuhua Bai. (2012) Comparative Studies on Chitosan and Polylactic-co-glycolic Acid Incorporated Nanoparticles of Low Molecular Weight Heparin. AAPS PharmSciTech 13:4, pages 1309-1318.
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Da Dong Guo, Hong Sheng Bi & Xiao Feng Xie. (2012) Fabrication and Characterization of Degradable Biomaterial Block Polymer PLGA Nanoparticles Modified by MePEG. Advanced Materials Research 548, pages 128-132.
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