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International Journal of Nanomedicine Volume 6, 2011 - Issue
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Original Research

Long-circulating delivery of bioactive polysaccharide from radix ophiopogonis by PEGylation

Xiao Lin1 Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China;2 College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China
,
Zhuo-Jun Wang2 College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China
,
Fang Huang3 Department of Nephrology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China
,
Shuang Liang1 Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China
,
Lan Shen2 College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China
,
Yi Feng1 Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
&
Ke-Feng Ruan1 Engineering Research Center of Modern Preparation Technology of TCM of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China
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Pages 2865-2872 | Published online: 11 Nov 2011

Citations (11)

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Read on this site (4)

Zhe Li, LiNa Wang, Xiao Lin, Lan Shen & Yi Feng. (2017) Drug delivery for bioactive polysaccharides to improve their drug-like properties and curative efficacy. Drug Delivery 24:2, pages 70-80.
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ChunXia Yao, XiaoLi Shi, Xiao Lin, Lan Shen, DeSheng Xu & Yi Feng. (2015) Increased cardiac distribution of mono-PEGylated Radix Ophiopogonis polysaccharide in both myocardial infarction and ischemia/reperfusion rats. International Journal of Nanomedicine 10, pages 409-418.
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XiaoLi Shi, Xiao Lin, XiangWei Zheng, Yi Feng & Lan Shen. (2014) Injectable long-acting systems for Radix Ophiopogonis polysaccharide based on mono-PEGylation and in situ formation of a PLGA depot. International Journal of Nanomedicine 9, pages 5555-5563.
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Hongjun Gao, Jinjian Liu, Cuihong Yang, Tangjian Cheng, Liping Chu, Hongyan Xu, Aimin Meng, Saijun Fan, Linqi Shi & Jianfeng Liu. (2013) The impact of PEGylation patterns on the in vivo biodistribution of mixed shell micelles. International Journal of Nanomedicine 8, pages 4229-4246.
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Articles from other publishers (7)

Samuel Eshorame Sanni, Adeyanju Adedayo Adedamola, Favour Ifi, Emeka Emmanuel Okoro, Babalola Aisosa Oni, Sarah Bitire & Rotimi Emmanuel Sadiku. 2023. Plant Polysaccharides as Pharmaceutical Excipients. Plant Polysaccharides as Pharmaceutical Excipients 429 452 .
Yi Sui, Wenjuan Liu, Wen Tian, Xiao-Qiang Li & Wei Cao. (2019) A branched arabinoglucan from Angelica sinensis ameliorates diabetic renal damage in rats . Phytotherapy Research 33:3, pages 818-831.
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Jiacheng Fang, Xiaoxiao Wang, Mengxin Lu, Xirui He & Xinhua Yang. (2018) Recent advances in polysaccharides from Ophiopogon japonicus and Liriope spicata var. prolifera. International Journal of Biological Macromolecules 114, pages 1257-1266.
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Ting Min, Jie Sun, Yang Yi, Hong-Xun Wang, Fei Hang, You-Wei Ai & Li-Mei Wang. (2015) Microanalysis, Pharmacokinetics and Tissue Distribution of Polysaccharide-Protein Complexes from Longan Pulp in Mice. International Journal of Molecular Sciences 16:10, pages 24403-24416.
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T. K. LimT. K. Lim. 2015. Edible Medicinal and Non Medicinal Plants. Edible Medicinal and Non Medicinal Plants 633 654 .
Xiaojiao Shang & Raja Ghosh. (2014) Membrane reactor for continuous and selective protein mono-PEGylation. Journal of Membrane Science 451, pages 177-184.
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GuiLan Sun, Xiao Lin, Lan Shen, Fei Wu, DeSheng Xu, KeFeng Ruan & Yi Feng. (2013) Mono-PEGylated radix ophiopogonis polysaccharide for the treatment of myocardial ischemia. European Journal of Pharmaceutical Sciences 49:4, pages 629-636.
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