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Original Research

Development and Optimization of Terpene-Enriched Vesicles (Terpesomes) for Effective Ocular Delivery of Fenticonazole Nitrate: In vitro Characterization and in vivo Assessment

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Pages 609-621 | Published online: 26 Jan 2021

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Oyku Simsekli, Irfan Bilinmis, Sumeyye Celik, Gizem Arık, Abdullah Yucel Baba & Alptug Karakucuk. (2023) Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes. Journal of Drug Targeting 31:9, pages 931-949.
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Sadek Ahmed, Maha M. Amin, Sarah Mohamed El-Korany & Sinar Sayed. (2022) Pronounced capping effect of olaminosomes as nanostructured platforms in ocular candidiasis management. Drug Delivery 29:1, pages 2945-2958.
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Rofida Albash, Rania Moataz El-Dahmy, Mohammed I. A. Hamed, Khaled M. Darwish, Abdulrahman M. Alahdal, Amira B. Kassem & Abdurrahman M. Fahmy. (2022) Repurposing levocetirizine hydrochloride loaded into cationic ceramide/phospholipid composite (CCPCs) for management of alopecia: central composite design optimization, in- silico and in-vivo studies. Drug Delivery 29:1, pages 2784-2795.
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Mahmoud H. Teaima, Moaz A. Eltabeeb, Mohamed A. El-Nabarawi & Menna M. Abdellatif. (2022) Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation. Drug Delivery 29:1, pages 2549-2560.
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Rofida Albash, Maha H. Ragaie, Mahmoud A. El Hassab, Radwan El-Haggar, Wagdy M. Eldehna, Sara T. Al-Rashood & Shaimaa Mosallam. (2022) Fenticonazole nitrate loaded trans-novasomes for effective management of tinea corporis: design characterization, in silico study, and exploratory clinical appraisal. Drug Delivery 29:1, pages 1100-1111.
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Rofida Albash, Menna M Abdellatif, Mariam Hassan & Noha M Badawi. (2021) Tailoring Terpesomes and Leciplex for the Effective Ocular Conveyance of Moxifloxacin Hydrochloride (Comparative Assessment): In-vitro, Ex-vivo, and In-vivo Evaluation. International Journal of Nanomedicine 16, pages 5247-5263.
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Mona G. Sakr, Sally A. El-Zahaby, Abdulaziz M. Al-Mahallawi & Dalia M. Ghorab. (2023) Fabrication of betaxolol hydrochloride-loaded highly permeable ocular bilosomes (HPOBs) to combat glaucoma: In vitro, ex vivo & in vivo characterizations. Journal of Drug Delivery Science and Technology 82, pages 104363.
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Moaz M. El-Naggar, Mohamed A. El-Nabarawi, Mahmoud H. Teaima, Mariam Hassan, Mohammed I.A. Hamed, Ahmed A. Elrashedy & Rofida Albash. (2023) Integration of terpesomes loaded Levocetrizine dihydrochloride gel as a repurposed cure for Methicillin-Resistant Staphylococcus aureus (MRSA)-Induced skin infection; D-optimal optimization, ex-vivo, in-silico, and in-vivo studies. International Journal of Pharmaceutics 633, pages 122621.
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Sara M. Soliman, Mahmoud Hassan Teaima, Kareem Omar Rashwan, Bassam Mohamed Ali, Bhaskara R. Jasti, Mohamed A El-Nabarawi & Shady M. Abd El-Halim. (2023) The deleterious effect of xylene-induced ear edema in rats: Protective role of dexketoprofen trometamol transdermal invasomes via inhibiting the oxidative stress/NF-κB/COX-2 pathway. International Journal of Pharmaceutics 631, pages 122525.
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Diana Aziz, Sally A. Mohamed, Saadia Tayel & Amal Makhlouf. (2022) Enhanced Ocular Anti-Aspergillus Activity of Tolnaftate Employing Novel Cosolvent-Modified Spanlastics: Formulation, Statistical Optimization, Kill Kinetics, Ex Vivo Trans-Corneal Permeation, In Vivo Histopathological and Susceptibility Study. Pharmaceutics 14:8, pages 1746.
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Shaimaa Mosallam, Rofida Albash & Manar Adel Abdelbari. (2022) Advanced Vesicular Systems for Antifungal Drug Delivery. AAPS PharmSciTech 23:6.
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Caroline Lamie, Enas Elmowafy, Dalia A. Attia, Mohamed M. Elmazar & Nahed D. Mortada. (2022) Diversifying the skin cancer-fighting worthwhile frontiers: How relevant are the itraconazole/ascorbyl palmitate nanovectors?. Nanomedicine: Nanotechnology, Biology and Medicine 43, pages 102561.
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Tingting Zhang, Xin Jin, Nan Zhang, Xinyi Jiao, Yuanyuan Ma, Rui Liu, Boshi Liu & Zheng Li. (2022) Targeted drug delivery vehicles mediated by nanocarriers and aptamers for posterior eye disease therapeutics: barriers, recent advances and potential opportunities. Nanotechnology 33:16, pages 162001.
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Leonna Dsouza, Pinal Chaudhari, Bheemisetty Brahmam & Shaila A. Lewis. (2021) Derma roller mediated transdermal delivery of tizanidine invasomes for the management of skeletal muscle spasms. European Journal of Pharmaceutical Sciences 165, pages 105920.
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Noha Ibrahim Elsherif, Abdulaziz Mohsen Al-Mahallawi, Abdelfattah Ahmed Abdelkhalek & Rehab Nabil Shamma. (2021) Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment. Pharmaceutics 13:5, pages 700.
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Abdulaziz M. Al-mahallawi, Aly A. Abdelbary & Sally A. El-Zahaby. (2021) Norfloxacin loaded nano-cubosomes for enhanced management of otitis externa: In vitro and in vivo evaluation. International Journal of Pharmaceutics 600, pages 120490.
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