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International Journal of Nanomedicine Volume 7, 2012 - Issue
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Original Research

RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating αvβ3 expression

Wencai Xu1 Department of Radiation Oncology, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai
,
Teng Luo2 School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai
,
Ping Li1 Department of Radiation Oncology, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai
,
Chuanqing Zhou2 School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai
,
Daxiang Cui3 National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai
,
Bo Pang4 Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, People’s Republic of China
,
Qiushi Ren4 Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Shen Fu1 Department of Radiation Oncology, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, ShanghaiCorrespondence[email protected] [email protected]
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Pages 915-924 | Published online: 27 Feb 2012

Citations (16)

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Zongjunlin Liu, Fang Xie, Jun Xie, Jianhao Chen, Yang Li, Qin Lin, Fanghong Luo & Jianghua Yan. (2021) New-generation photosensitizer-anchored gold nanorods for a single near-infrared light-triggered targeted photodynamic–photothermal therapy. Drug Delivery 28:1, pages 1769-1784.
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Yupeng Liu, Suhuan Dai, Lijuan Wen, Yun Zhu, Yanan Tan, Guoxi Qiu, Tingting Meng, Fangying Yu, Hong Yuan & Fuqiang Hu. (2020) Enhancing Drug Delivery for Overcoming Angiogenesis and Improving the Phototherapy Efficacy of Glioblastoma by ICG-Loaded Glycolipid-Like Micelles. International Journal of Nanomedicine 15, pages 2717-2732.
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Xiaodong Han, Xiaojia Jiang, Lanjie Guo, Yongxin Wang, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Zhigang Wang & Dandan Cao. (2019) Anticarcinogenic potential of gold nanoparticles synthesized from Trichosanthes kirilowii in colon cancer cells through the induction of apoptotic pathway. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 3577-3584.
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Ning Zhao, Zhangru Yang, Bingxin Li, Jin Meng, Zeliang Shi, Ping Li & Shen Fu. (2016) RGD-conjugated mesoporous silica-encapsulated gold nanorods enhance the sensitization of triple-negative breast cancer to megavoltage radiation therapy. International Journal of Nanomedicine 11, pages 5595-5610.
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Jae Yeon Joo, Gil Yong Park & Seong Soo A An. (2015) Biocompatible and biodegradable fibrinogen microspheres for tumor-targeted doxorubicin delivery. International Journal of Nanomedicine 10:sup1, pages 101-111.
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Articles from other publishers (11)

V. F. Mikhailov & L. V. Shulenina. (2023) Regulation of Gene Activity Is One of the Mechanisms for Changing Radiosensitivity. Biology Bulletin 49:11, pages 2032-2042.
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Syed Nasir Abbas Bukhari. (2022) Emerging Nanotherapeutic Approaches to Overcome Drug Resistance in Cancers with Update on Clinical Trials. Pharmaceutics 14:4, pages 866.
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Mei-Hsiu Chen, Ming-Hong Chen, Chia-Ying Li, Fu-I Tung, San-Yuan Chen & Tse-Ying Liu. (2021) Using Gold-Nanorod-Filled Mesoporous Silica Nanobeads for Enhanced Radiotherapy of Oral Squamous Carcinoma. Nanomaterials 11:9, pages 2235.
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Ioanna Tremi, Ellas Spyratou, Maria Souli, Efstathios P. Efstathopoulos, Mersini Makropoulou, Alexandros G. Georgakilas & Lembit Sihver. (2021) Requirements for Designing an Effective Metallic Nanoparticle (NP)-Boosted Radiation Therapy (RT). Cancers 13:13, pages 3185.
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Soumya Menon & Venkat Kumar Shanmugam. (2020) Chemopreventive mechanism of action by oxidative stress and toxicity induced surface decorated selenium nanoparticles. Journal of Trace Elements in Medicine and Biology 62, pages 126549.
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Matthew I. Confeld, Babak Mamnoon, Li Feng, Heather Jensen-Smith, Priyanka Ray, James Froberg, Jiha Kim, Michael A. Hollingsworth, Mohiuddin Quadir, Yongki Choi & Sanku Mallik. (2020) Targeting the Tumor Core: Hypoxia-Responsive Nanoparticles for the Delivery of Chemotherapy to Pancreatic Tumors. Molecular Pharmaceutics 17:8, pages 2849-2863.
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Hainan Sun, Xiaoling Wang & Shumei Zhai. (2020) The Rational Design and Biological Mechanisms of Nanoradiosensitizers. Nanomaterials 10:3, pages 504.
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Nthabeleng Hlapisi, Tshwafo E. Motaung, Linda Z. Linganiso, Oluwatobi S. Oluwafemi & Sandile P. Songca. (2019) Encapsulation of Gold Nanorods with Porphyrins for the Potential Treatment of Cancer and Bacterial Diseases: A Critical Review. Bioinorganic Chemistry and Applications 2019, pages 1-27.
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Marius Mioc, Ioana Zinuca Pavel, Roxana Ghiulai, Dorina E. Coricovac, Claudia Farcaş, Ciprian-Valentin Mihali, Camelia Oprean, Vlad Serafim, Ramona A. Popovici, Cristina A. Dehelean, Michael I. Shtilman, Aristidis M. Tsatsakis & Codruţa Şoica. (2018) The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells. Frontiers in Pharmacology 9.
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Seamkwan Komenek, Urarika Luesakul, Sanong Ekgasit, Tirayut Vilaivan, Narong Praphairaksit, Songchan Puthong & Nongnuj Muangsin. (2016) Nanogold-Gallate Chitosan-Targeted Pulmonary Delivery for Treatment of Lung Cancer. AAPS PharmSciTech 18:4, pages 1104-1115.
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Daniel R. Cooper, Devesh Bekah & Jay L. Nadeau. (2014) Gold nanoparticles and their alternatives for radiation therapy enhancement. Frontiers in Chemistry 2.
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