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International Journal of Nanomedicine Volume 7, 2012 - Issue
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Original Research

A silica-based pH-sensitive nanomatrix system improves the oral absorption and efficacy of incretin hormone glucagon-like peptide-1

Wei Qu1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China;2 Department of Nutrition and Food Hygiene, Peking University Health Science Center, Beijing 100191, PR China
,
Yong Li2 Department of Nutrition and Food Hygiene, Peking University Health Science Center, Beijing 100191, PR ChinaCorrespondence[email protected] [email protected]
,
Lars Hovgaard3 Oral Formulation Development, Novo Nordisk A/S, Maalov, Denmark
,
Song Li1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
,
Wenbin Dai1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
,
Jiancheng Wang1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
,
Xuan Zhang1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
&
Qiang Zhang1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR ChinaCorrespondence[email protected] [email protected]
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Pages 4983-4994 | Published online: 14 Sep 2012

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Ali Kermanizadeh, Leagh G Powell, Vicki Stone & Peter Møller. (2018) Nanodelivery systems and stabilized solid-drug nanoparticles for orally administered medicine: current landscape. International Journal of Nanomedicine 13, pages 7575-7605.
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Lin Liu, WenDong Yao, YueFeng Rao, XiaoYang Lu & JianQing Gao. (2017) pH-Responsive carriers for oral drug delivery: challenges and opportunities of current platforms. Drug Delivery 24:1, pages 569-581.
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Francisca Araújo, Neha Shrestha, Pedro L Granja, Jouni Hirvonen, Hélder A Santos & Bruno Sarmento. (2015) Safety and toxicity concerns of orally delivered nanoparticles as drug carriers. Expert Opinion on Drug Metabolism & Toxicology 11:3, pages 381-393.
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Dustin L Cooper, Christopher M Conder & Sam Harirforoosh. (2014) Nanoparticles in drug delivery: mechanism of action, formulation and clinical application towards reduction in drug-associated nephrotoxicity. Expert Opinion on Drug Delivery 11:10, pages 1661-1680.
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Articles from other publishers (2)

Nabilah Ibnat, Rahela Zaman, Mohammad Borhan Uddin, Ezharul Chowdhury & Chooi Yeng Lee. (2022) Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats. World Journal of Diabetes 13:8, pages 613-621.
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Faruk H. Moonschi, Corey B. Hughes, George M. Mussman, John L. Fowlkes, Chris I. Richards & Iuliana Popescu. (2017) Advances in micro- and nanotechnologies for the GLP-1-based therapy and imaging of pancreatic beta-cells. Acta Diabetologica 55:5, pages 405-418.
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