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Original Research
A silica-based pH-sensitive nanomatrix system improves the oral absorption and efficacy of incretin hormone glucagon-like peptide-1
Wei Qu1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China;2 Department of Nutrition and Food Hygiene, Peking University Health Science Center, Beijing 100191, PR China
, Yong Li2 Department of Nutrition and Food Hygiene, Peking University Health Science Center, Beijing 100191, PR ChinaCorrespondence[email protected] [email protected]
, Lars Hovgaard3 Oral Formulation Development, Novo Nordisk A/S, Maalov, Denmark
, Song Li1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
, Wenbin Dai1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
, Jiancheng Wang1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
, Xuan Zhang1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China
& Qiang Zhang1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR ChinaCorrespondence[email protected] [email protected]
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Pages 4983-4994
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Published online: 14 Sep 2012
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