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Original Research

Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs

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Pages 2473-2481 | Published online: 05 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Snigdha Tiash & Ezharul Hoque Chowdhury. (2019) siRNAs targeting multidrug transporter genes sensitise breast tumour to doxorubicin in a syngeneic mouse model. Journal of Drug Targeting 27:3, pages 325-337.
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Aayushi Jain, Devashree Jahagirdar, Pritish Nilendu & Nilesh Kumar Sharma. (2017) Molecular approaches to potentiate cisplatin responsiveness in carcinoma therapeutics. Expert Review of Anticancer Therapy 17:9, pages 815-825.
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Weipeng Zhang, Xiaowei Zheng, Ti Meng, Haisheng You, Yalin Dong, Jianfeng Xing & Siying Chen. (2017) SET protein overexpression contributes to paclitaxel resistance in MCF-7/S cells through PI3K/Akt pathway. Journal of Drug Targeting 25:3, pages 255-263.
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Mehri Niazi, Parvin Zakeri-Milani, Saeedeh Najafi Hajivar, Mehdi Soleymani Goloujeh, Nasrin Ghobakhlou, Javid Shahbazi Mojarrad & Hadi Valizadeh. (2016) Nano-based strategies to overcome p-glycoprotein-mediated drug resistance. Expert Opinion on Drug Metabolism & Toxicology 12:9, pages 1021-1033.
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Wei Fan, Xiang Wang, Baoyue Ding, Haimin Cai, Xudong Wang, Yueqi Fan, Yong Li, Shenghui Liu, Suifeng Nie & Qiping Lu. (2016) Thioaptamer-conjugated CD44-targeted delivery system for the treatment of breast cancer in vitro and in vivo. Journal of Drug Targeting 24:4, pages 359-371.
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Wen Jen Lin & Li Ting Kao. (2014) Cytotoxic enhancement of hexapeptide-conjugated micelles in EGFR high-expressed cancer cells. Expert Opinion on Drug Delivery 11:10, pages 1537-1550.
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Alice Panariti, Giuseppe Miserocchi & Ilaria Rivolta. (2012) The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions?. Nanotechnology, Science and Applications 5, pages 87-100.
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Articles from other publishers (8)

He-Hua Zhang, Jian Xiang, Bin-Cheng Yin & Bang-Ce Ye. (2023) Overcoming Multidrug Resistance by Base-Editing-Induced Codon Mutation. ACS Pharmacology & Translational Science 6:5, pages 812-819.
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Daoyuan Chen, Xuecun Liu, Xiaoyan Lu & Jingwei Tian. (2023) Nanoparticle drug delivery systems for synergistic delivery of tumor therapy. Frontiers in Pharmacology 14.
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Göknur KARA. (2022) siRNA targeting ABCB1 potentiates the efficacy of chemotherapy in human triple-negative breast cancer cells. Hacettepe Journal of Biology and Chemistry 50:4, pages 349-358.
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Rouba D. Al Bostami, Waad H. Abuwatfa & Ghaleb A. Husseini. (2022) Recent Advances in Nanoparticle-Based Co-Delivery Systems for Cancer Therapy. Nanomaterials 12:15, pages 2672.
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Xue Zeng, Zhe Cao, Wenhao Luo, Lianfang Zheng & Taiping Zhang. (2020) MicroRNA-381—A Key Transcriptional Regulator: Its Biological Function and Clinical Application Prospects in Cancer. Frontiers in Oncology 10.
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David Gomez-Zepeda, Méryam Taghi, Jean-Michel Scherrmann, Xavier Decleves & Marie-Claude Menet. (2019) ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas. Pharmaceutics 12:1, pages 20.
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Qiong Wu, Soni Sharma, Hang Cui, Scott E. LeBlanc, Hong Zhang, Rohini Muthuswami, Jeffrey A. Nickerson & Anthony N. Imbalzano. (2016) Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells. Oncotarget 7:19, pages 27158-27175.
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Thalagalage Shalika Harshani Perera, Yingchao Han, Xiaofei Lu, Xinyu Wang, Honglian Dai & Shipu Li. (2015) Rare Earth Doped Apatite Nanomaterials for Biological Application. Journal of Nanomaterials 2015, pages 1-6.
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