Advanced search
Publication Cover
International Journal of Nanomedicine Volume 8, 2013 - Issue
Submit an article Journal homepage
189
Views
20
CrossRef citations to date
0
Altmetric
Original Research

Design, physicochemical characterization, and optimization of organic solution advanced spray-dried inhalable dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylethanolamine poly(ethylene glycol) (DPPE-PEG) microparticles and nanoparticles for targeted respiratory nanomedicine delivery as dry powder inhalation aerosols

Samantha A Meenach1 Department of Pharmaceutical Sciences-Drug Development Division, University of Kentucky College of Pharmacy, Lexington, KY;;2 Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY, USA;
,
Frederick G Vogt3 Analytical Sciences, Product Development, GlaxoSmithKline, King of Prussia, PA;
,
Kimberly W Anderson2 Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY, USA;;4 Center of Membrane Sciences, University of Kentucky, Lexington, KY
,
J Zach Hilt2 Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY, USA;;4 Center of Membrane Sciences, University of Kentucky, Lexington, KY
,
Ronald C McGarry5 Department of Radiation Medicine, University of Kentucky College of Medicine, Lexington, KY, USA
&
Heidi M Mansour1 Department of Pharmaceutical Sciences-Drug Development Division, University of Kentucky College of Pharmacy, Lexington, KY;;4 Center of Membrane Sciences, University of Kentucky, Lexington, KYCorrespondence[email protected]
Pages 275-293 | Published online: 14 Jan 2013

Citations (20)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (12)

Mohamed Fawzi Kabil, Osama A. Badary, Frank Bier, Shaker A. Mousa & Ibrahim M. El-Sherbiny. (2023) A comprehensive review on lipid nanocarrier systems for cancer treatment: fabrication, future prospects and clinical trials. Journal of Liposome Research 0:0, pages 1-43.
Read now
Ji-Hyun Kang, Min-Seok Yang, Dong-Wook Kim & Chun-Woong Park. (2022) In vivo pharmacokinetic and pharmacodynamic study of co-spray-dried inhalable pirfenidone microparticles in rats. Drug Delivery 29:1, pages 3384-3396.
Read now
Shilpa Kakkar, Mandeep Singh, Sankunny Mohan Karuppayil, Jayant S. Raut, Fabrizio Giansanti, Laura Papucci, Nicola Schiavone, T. C. Nag, Nan Gao, Fu-Shin X. Yu, Mohhammad Ramzan & Indu Pal Kaur. (2021) Lipo-PEG nano-ocular formulation successfully encapsulates hydrophilic fluconazole and traverses corneal and non-corneal path to reach posterior eye segment. Journal of Drug Targeting 29:6, pages 631-650.
Read now
Nazafarin Satari, Somayeh Taymouri, Jaleh Varshosaz, Mahboubeh Rostami & Mina Mirian. (2020) Preparation and evaluation of inhalable dry powder containing glucosamine-conjugated gefitinib SLNs for lung cancer therapy. Drug Development and Industrial Pharmacy 46:8, pages 1265-1277.
Read now
Nishan K. Shah, Zimeng Wang, Sweta K. Gupta, Andrew Le Campion & Samantha A. Meenach. (2019) Sustained release of a model water-soluble compound via dry powder aerosolizable acetalated dextran microparticles. Pharmaceutical Development and Technology 24:9, pages 1133-1143.
Read now
Zara Sheikh, Hui Xin Ong, Michele Pozzoli, Paul M Young & Daniela Traini. (2018) Is there a role for inhaled anti-inflammatory drugs in cystic fibrosis treatment?. Expert Opinion on Orphan Drugs 6:1, pages 69-84.
Read now
Priya Muralidharan, Don Hayes$suffix/text()$suffix/text() & Heidi M Mansour. (2015) Dry powder inhalers in COPD, lung inflammation and pulmonary infections. Expert Opinion on Drug Delivery 12:6, pages 947-962.
Read now
Yung-Chih Kuo & Che-Yu Lin. (2015) Targeting delivery of liposomes with conjugated p-aminophenyl-α-d-manno-pyranoside and apolipoprotein E for inhibiting neuronal degeneration insulted with β-amyloid peptide. Journal of Drug Targeting 23:2, pages 147-158.
Read now
Jinghua Duan, Frederick G Vogt, Xiaojian Li, Don Hayes$suffix/text()$suffix/text() & Heidi M Mansour. (2013) Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery. International Journal of Nanomedicine 8, pages 3489-3505.
Read now
Jingjing Dong, Geng Cui, Long Bi, Jie Li & Wei Lei. (2013) The mechanical and biological studies of calcium phosphate cement-fibrin glue for bone reconstruction of rabbit femoral defects. International Journal of Nanomedicine 8, pages 1317-1324.
Read now
Xiao Wu, Weifen Zhang, Don Hayes$suffix/text()$suffix/text() & Heidi M Mansour. (2013) Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried cyclosporine A multifunctional particles for dry powder inhalation aerosol delivery. International Journal of Nanomedicine 8, pages 1269-1283.
Read now
Xiao Wu, Don Hayes$suffix/text()$suffix/text(), Joseph B Zwischenberger, Robert J Kuhn & Heidi M Mansour. (2013) Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation. Drug Design, Development and Therapy 7, pages 59-72.
Read now

Articles from other publishers (8)

Wafaa Alabsi, Maria F. Acosta, Fahad A. Al-Obeidi, Meredith Hay, Robin Polt & Heidi M. Mansour. (2021) Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1—7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers. Pharmaceutics 13:8, pages 1278.
Crossref
Priya Muralidharan, Maria F. Acosta, Alexan I. Gomez, Carissa Grijalva, Haiyang Tang, Jason X.-J. Yuan & Heidi M. Mansour. (2021) Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy. Antioxidants 10:3, pages 427.
Crossref
Maria F. Acosta, Michael D. Abrahamson, David Encinas-Basurto, Jeffrey R. Fineman, Stephen M. Black & Heidi M. Mansour. (2020) Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder Inhalers. The AAPS Journal 23:1.
Crossref
Wafaa Alabsi, Fahad A. Al-Obeidi, Robin Polt & Heidi M. Mansour. (2020) Organic Solution Advanced Spray-Dried Microparticulate/Nanoparticulate Dry Powders of Lactomorphin for Respiratory Delivery: Physicochemical Characterization, In Vitro Aerosol Dispersion, and Cellular Studies. Pharmaceutics 13:1, pages 26.
Crossref
Priya Muralidharan, Brielle Jones, Graham Allaway, Shyam S. Biswal & Heidi M. Mansour. (2020) Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist. Scientific Reports 10:1.
Crossref
Yi Zhu, Guonan Zhang, Meiying Li, Lang Ma, Jianming Huang & Li Qiu. (2020) Ultrasound-Augmented Phase Transition Nanobubbles for Targeted Treatment of Paclitaxel-Resistant Cancer. Bioconjugate Chemistry 31:8, pages 2008-2020.
Crossref
Stefano Nobile & Lucio Nobile. (2020) Nanotechnology and Early Human Development. Applied Sciences 10:12, pages 4323.
Crossref
Elisa A. Torrico Guzmán, Qihua Sun & Samantha A. Meenach. (2019) Development and Evaluation of Paclitaxel-Loaded Aerosol Nanocomposite Microparticles and Their Efficacy Against Air-Grown Lung Cancer Tumor Spheroids. ACS Biomaterials Science & Engineering 5:12, pages 6570-6580.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.