Design, physicochemical characterization, and optimization of organic solution advanced spray-dried inhalable dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylethanolamine poly(ethylene glycol) (DPPE-PEG) microparticles and nanoparticles for targeted respiratory nanomedicine delivery as dry powder inhalation aerosols

References

• CarvalhoTCCarbalhoSRMcConvilleJTFormulations for pulmonary administration of anticancer agents to treat lung malignanciesJ Aerosol Med Pulm Drug Deliv201124618021410326
   PubMed Web of Science ®Google Scholar
• MansourHMRheeYSWuXNanomedicine in pulmonary deliveryInt J Nanomedicine2009429931920054434
   PubMed Web of Science ®Google Scholar
• VaughnJMMcConvilleJTBurgessDSing dose and multiple dose studies of itraconazole nanoparticlesEur J Pharm Biopharm2006639510216516450
   PubMed Web of Science ®Google Scholar
• GillSLöbenbergRKuTAzarmiSRoaWHPrennerEJNanoparticles: characteristics, mechanisms of action, and toxicity in pulmonary drug delivery – a reviewJ Biomed Nanotechnol20073107119
   Web of Science ®Google Scholar
• YangYBajajNXuPOhnKTsifanskyMDYeoYDevelopment of highly porous large PLGA microparticles for pulmonary drug deliveryBiomaterials2009301947195319135245
   PubMed Web of Science ®Google Scholar
• SharmaSWhiteDImondiAPlackeMEVailDMKrisMGDevelopment of inhalation agents for oncologic useJ Clin Oncol2001191839184711251016
   PubMed Web of Science ®Google Scholar
• HickeyAJMansourHMDelivery of drugs by the pulmonary routeFlorenceATSiepmannJModern Pharmaceutics5th edNew YorkTaylor and Francis20092191219
   Google Scholar
• HickeyAJMansourHMFormulation challenges of powders for the delivery of small molecular weight molecules as aerosolsRathboneMJHadgraftJRobertsMSLaneMEModified-Release Drug Delivery Technology2nd edNew YorkInforma Healthcare20082573602
   Google Scholar
• ArnoldMMGonnanEMSchieberLJMunsonEJBerklandCNanoCipro encapsulation in monodisperse large porous PLGA microparticlesJ Control Release200712110010917604870
   PubMed Web of Science ®Google Scholar
• CartieraMSFerreiraECCaputoCEganMECaplanMJSaltzmanWMPartial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcuminMol Pharm20107869319886674
   PubMed Web of Science ®Google Scholar
• MeenachSAKimYJKauffmanKJKanthamneniNBachelderEMAinslieKMSynthesis, optimization, and characterization of camptothecin-loaded acetalated dextran porous microparticles for pulmonary deliveryMol Pharm2012929029822149217
   PubMed Web of Science ®Google Scholar
• OhYJLeeJSeoJYPreparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma modelJ Control Release2011150566221070826
   PubMed Web of Science ®Google Scholar
• WuXALiXJMansourHMSurface analytical techniques in solidstate particle characterization for predicting performance in dry powder inhalersKona Powder Part J201028319
   Google Scholar
• MansourHMRheeYSParkCWDeLucaPPLipid nanoparticulate drug delivery and nanomedicineMoghisALipids in Nano-technologyUrbana (IL)American Oil Chemists Society (AOCS) Press2011221268
   Google Scholar
• WattsABMcConvilleJTWilliamsROAdvancements in dry powder delivery to the lungDrug Dev Ind Pharm20083494895918800256
   PubMed Web of Science ®Google Scholar
• PattonJSByronPRInhaling medicines: delivering drugs to the body through the lungsNat Rev Drug Discov20076677417195033
   PubMed Web of Science ®Google Scholar
• SungJCPulliamBLEdwardsDANanoparticles for drug delivery to the lungsTrends Biotechnol20072556357017997181
   PubMed Web of Science ®Google Scholar
• LaubeBLJanssensHMde JonghFHCWhat the pulmonary specialist should know about inhalation therapiesEur Respir J2011371308133121310878
   PubMed Web of Science ®Google Scholar
• XuZMansourHMHickeyAJParticle interations in dry powder inhaler unit processesJ Adhes Sci Technol201125451482
   Web of Science ®Google Scholar
• RheeYSMansourHMNanopharmaceuticals I: nanocarrier systems in drug delivery. Invited paperInt J Nanotechnology2011884114
   Web of Science ®Google Scholar
• WuXMansourHMNanopharmaceuticals II: application of nano-particles and nanocarrier systems in pharmaceutics and nanomedicine. Invited paperInt J Nanotechnology20118115145
   Web of Science ®Google Scholar
• WillisLHayesDJMansourHMTherapeutic liposomal dry powder inhalation aerosols for targeted lung deliveryLung201219025126222274758
   PubMed Web of Science ®Google Scholar
• GangulySMoolchandaniVRocheJAPhospholipid-induced in vivo particle migration to enhance pulmonary depositionJ Aerosol Med Pulm Drug Deliv200823181187
   Google Scholar
• MansourHMZografiGThe relationship between water vapor absorption and desorption by phospholipids and bilayer phase transitionsJ Pharm Sci20079637739617080427
   PubMed Web of Science ®Google Scholar
• MansourHWangDSChenCSZografiGComparison of bilayer and monolayer properties of phospholipid systems containing dipalmitoylphosphatidylglycerol and dipalmitoylphosphatidylinositolLangmuir20011766226632
   Web of Science ®Google Scholar
• MansourHMZografiGRelationships between equilibrium spreading pressure and phase equilibria of phospholipid bilayers and monolayers at the air-water interfaceLangmuir2007233809381917323986
   PubMed Web of Science ®Google Scholar
• MansourHMDamodaranSZografiGCharacterization of the in situ structural and interfacial properties of the cationic hydrophobic heteropolypeptide, KL4, in lung surfactant bilayer and monolayer models at the air-water interface: implications for pulmonary surfactant deliveryMol Pharm2008568169518630875
   PubMed Web of Science ®Google Scholar
• MabreySSturtevantJMInvestigation of phase transitions of lipids and lipid mixtures by high sensitivity differential scanning calorimetryProc Natl Acad Sci U S A197673386238661069270
   PubMed Web of Science ®Google Scholar
• LabirisNRDolovichMBPulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medicationsBr J Clin Pharmacol20035658859914616418
   PubMed Web of Science ®Google Scholar
• LabirisNRDolovichMBPulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulation in therapeutic effectiveness of aerosolized medicationsBr J Clin Pharmacol20035660061214616419
   PubMed Web of Science ®Google Scholar
• IshiharaKNomuraHMiharaTKuritaKIwasakiYNakabayashiNWhy do phospholipid polymers reduce protein adsorption?J Biomed Mater Res1998393233309457564
   PubMed Web of Science ®Google Scholar
• MansourHMSohnMAl-GhananeemADelucaPPMaterials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspectsInt J Mol Sci2010113298332220957095
   PubMed Web of Science ®Google Scholar
• LaiSKO’HanlonDEHarroldSRapid transport of large polymeric nanoparticles in fresh undiluted human mucusProc Natl Acad Sci U S A20071041482148717244708
   PubMed Web of Science ®Google Scholar
• SadikotRTRubinsteinILong-acting, multi-targeted nanomedicine: addressing unmet medical need in acute lung injuryJ Biomed Nanotechnol2009561461920201223
   PubMed Web of Science ®Google Scholar
• LimSBRubinsteinISadikotRTArtwohlJEÖnyükselHA novel peptide nanomedicine against acute lung injury: GLP-1 in phospholipid micellesPharm Res20112866267221108040
   PubMed Web of Science ®Google Scholar
• KikuchiHYamauchiHHirotaSA spray-drying method for mass production of liposomesChem Pharm Bull19913615221527
   Google Scholar
• AlvesGPSantanaMHAPhospholipid dry powders produced by spray drying processing: structural, thermodynamic and physical propertiesPowder Technol2004145139148
   Web of Science ®Google Scholar
• CruzLFattalETassoLFormulation and in vivo evaluation of sodium alendronate spray-dried microparticles intended for lung deliveryJ Control Release201115237037521396412
   PubMed Web of Science ®Google Scholar
• BosquillonCLombryCPreatVVanbeverRInfuence of formulation excipients and physical characterisitcs of inhalation dry powders on their aerosolization performanceJ Control Release20017032933911182203
   PubMed Web of Science ®Google Scholar
• BiRShaoWWangQZhangNSpray-freeze-dried dry powder inhalation of insulin-loaded liposomes for enhanced pulmonary deliveryJ Drug Target20081663964818982512
   PubMed Web of Science ®Google Scholar
• MastersKSpray Drying Handbook5th edHarlow, UKLongman1991
   Google Scholar
• LiXMansourHMPhysicochemical characterization and water vapor absorption of organic solution advanced spray dried trehalose microparticles and nanoparticles for targeted dry powder pulmonary inhalation deliveryAAPS Pharm Sci Tech20111214201430
   PubMed Web of Science ®Google Scholar
• ParkCWRheeYSVogtFAdvances in microscopy and complementary imaging techniques to assess the fate of drugs ex-vivo in respiratory drug delivery: an invited paperAdv Drug Deliv Rev20126434435621920394
   PubMed Web of Science ®Google Scholar
• Chapter 601. Aerosols, nasal sprays, metered-dose inhalers, and dry powder inhalers monographUSP 29-NF 24: United States Pharmacopoeia and the National Formulary: The Official Compendia of StandardsVol 29/24Rockville, MDUnited States Pharmacopeial Convention200626172636
   Google Scholar
• EdwardsDABen-JebriaALangerRRecent advances in pulmonary drug delivery using large, porous inhaled particlesJ Appl Physiol1998853793859688708
   PubMed Web of Science ®Google Scholar
• KangERobinsonJParkKChengJXPaclitaxel distribution in poly(ethylene glycol)/poly(lactide-co-glycolic acid) blends and its release visualized by coherent anti-Stokes Raman scattering microscopyJ Control Release200712226126817574291
   PubMed Web of Science ®Google Scholar
• JonesBGDickinsonPAGumbletonMKellawayIWThe inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophagesInt J Pharm2002236657911891071
   PubMed Web of Science ®Google Scholar
• WuYPZuoFZhengZHDingXBPengYXA novel approach to molecular recognition surface of magnetic nanoparticles based on host-guest effectNanoscale Res Lett2009473874720596347
   PubMed Web of Science ®Google Scholar
• Li X, Hayes D, Mansour HMTargeted lung delivery by inhalable multifunctional microparticulate/nanoparticulate aerosols for cystic fibrosis combination drug/mucolytic treatmentPediatric Pulmonology201134Suppl346
   Google Scholar
• AzarmiSRoaWHLobenbergRTargeted delivery of nanoparticles for the treatment of lung diseasesAdv Drug Deliv Rev20086086387518308418
   PubMed Web of Science ®Google Scholar
• GautamATargeted delivery of therapeutics by aerosol for cancer of the lungCurr Cancer Drug Targets200335712570661
   PubMed Web of Science ®Google Scholar
• EdwardsDAThe macrotransport of aerosol particles in the lung: aerosol deposition phenomenaJ Aerosol Sci199526293317
   Web of Science ®Google Scholar
• HickeyAJMansourHMTelkoMTPhysical characterization of component particles included in dry powder inhalers. I. Strategy review and static characteristicsJ Pharm Sci2007961282130117455324
   PubMed Web of Science ®Google Scholar
• VanbeverRBen-JebriaAMintzesJLangerCEdwardsDASustained release of insulin from insoluble inhaled particlesDrug Dev Res199948178185
   Web of Science ®Google Scholar
• UngaroFDe RosaGMiroAQuagliaFLa RotondaMICyclodextrins in the production of large porous particles: development of dry powders for the sustained release of insulin to the lungsEur J Pharm Sci20062842343216806857
   PubMed Web of Science ®Google Scholar