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International Journal of Nanomedicine Volume 7, 2012 - Issue
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Original Research

Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity

Peihao Yin1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
,
Yan Wang1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
,
YanYan Qiu1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
,
LiLi Hou1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
,
Xuan Liu1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
,
Jianmin Qin1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
,
Yourong Duan2 Shanghai Cancer Institute, Jiaotong University, Shanghai, China
,
Peifeng Liu2 Shanghai Cancer Institute, Jiaotong University, Shanghai, China
,
Ming Qiu3 Department of General Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, ChinaCorrespondence[email protected]
&
Qi Li1 Department of Clinical Oncology, Putuo Hospital and Interventional Cancer Institute of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaCorrespondence[email protected]
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Pages 3961-3969 | Published online: 27 Jul 2012

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Zeting Yuan, Yuxia Yuan, Lin Han, Yanyan Qiu, Xiaqin Huang, Feng Gao, Guohua Fan, Yixi Zhang, Xueyao Tang, Xue He, Ke Xu & Peihao Yin. (2018) Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer. International Journal of Nanomedicine 13, pages 7533-7548.
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Meng Wu, Ying Wang, Yiru Wang, Mingbo Zhang, Yukun Luo, Jie Tang, Zhigang Wang, Dong Wang, Lan Hao & Zhibiao Wang. (2017) Paclitaxel-loaded and A10-3.2 aptamer-targeted poly(lactide-co-glycolic acid) nanobubbles for ultrasound imaging and therapy of prostate cancer. International Journal of Nanomedicine 12, pages 5313-5330.
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Xiangyu Zhang, Qi Wang, Liubing Qin, Hao Fu, Yiwei Fang, Baoshan Han & Yourong Duan. (2016) EGF-modified mPEG-PLGA-PLL nanoparticle for delivering doxorubicin combined with Bcl-2 siRNA as a potential treatment strategy for lung cancer. Drug Delivery 23:8, pages 2936-2945.
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Qiang Hu, Bo Liang, Ying Sun, Xiao-Ling Guo, Yi-Jie Bao, Dong-Hao Xie, Ming Zhou, You-Rong Duan, Pei-Hao Yin & Zhi-Hai Peng. (2014) Preparation of bufalin-loaded pluronic polyetherimide nanoparticles, cellular uptake, distribution, and effect on colorectal cancer. International Journal of Nanomedicine 9, pages 4035-4041.
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Haiyan Sun, Dong Liu, Yan Li, Xuwei Tang & Yanli Cong. (2014) Preparation and in vitro/in vivo characterization of enteric-coated nanoparticles loaded with the antihypertensive peptide VLPVPR. International Journal of Nanomedicine 9, pages 1709-1716.
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Ana Ferreira Ribeiro, Ricardo Leite de Oliveira Rezende, Lúcio Mendes Cabral & Valéria Pereira de Sousa. (2013) Poly ɛ-caprolactone nanoparticles loaded with Uncaria tomentosa extract: preparation, characterization, and optimization using the Box–Behnken design. International Journal of Nanomedicine 8, pages 431-442.
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Articles from other publishers (8)

Akmal M. Asrorov, Muzaffar Kayumov, Nurkhodja Mukhamedov, Ansor Yashinov, Ziyoda Mirakhmetova, Yongzhuo Huang, Abulimiti Yili, Haji Akber Aisa, Mugrajitdin Tashmukhamedov, Shavkat Salikhov & Sharafitdin Mirzaakhmedov. (2023) Toad venom bufadienolides and bufotoxins: An updated review. Drug Development Research 84:5, pages 815-838.
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Shivani DeshmukhBharati ChaudhariAtish VelhalVivekkumar Redasani. (2022) A Compendious Review on Biodegradable Polymeric Nanoparticles. Asian Journal of Pharmacy and Technology, pages 371-381.
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Yuchen Tian, Anggrek C. Nusantara, Thamir Hamoh, Aldona Mzyk, Xiaobo Tian, Felipe Perona Martinez, Runrun Li, Hjalmar P. Permentier & Romana Schirhagl. (2022) Functionalized Fluorescent Nanodiamonds for Simultaneous Drug Delivery and Quantum Sensing in HeLa Cells. ACS Applied Materials & Interfaces 14:34, pages 39265-39273.
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Xia Sheng, Pengfei Zhu, Yi Zhao, Jinwei Zhang, Haijia Li, Huan Zhao & Jianmin Qin. (2021) Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin. Recent Patents on Anti-Cancer Drug Discovery 16:1, pages 54-65.
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Aarti D. Rohira & David M. Lonard. (2017) Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers. Biochemical Pharmacology 140, pages 1-7.
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Ze-Ting Yuan, Xiao-Jing Shi, Yu-Xia Yuan, Yan-Yan Qiu, Yu Zou, Cheng Liu, Hui Yu, Xue He, Ke Xu & Pei-Hao Yin. (2017) Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer. Oncotarget 8:29, pages 48012-48026.
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Hongyan Zhao, Qinghua Li, Jie Pang, Huilin Jin, Hongwei Li & Xiaoying Yang. (2017) Blocking autophagy enhances the pro-apoptotic effect of bufalin on human gastric cancer cells through endoplasmic reticulum stress. Biology Open.
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Edel Sah & Hongkee Sah. (2015) Recent Trends in Preparation of Poly(lactide- co -glycolide) Nanoparticles by Mixing Polymeric Organic Solution with Antisolvent . Journal of Nanomaterials 2015, pages 1-22.
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