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International Journal of Nanomedicine Volume 17, 2023 - Issue
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Original Research

Chitosan-Coated-PLGA Nanoparticles Enhance the Antitumor and Antimigration Activity of Stattic – A STAT3 Dimerization Blocker

Stephanie Sally Fong1 Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Yiing Yee Foo1 Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Wen Shang Saw2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, 50603, MalaysiaORCID Iconhttps://orcid.org/0000-0003-2120-8399
ORCID Icon,
Bey Fen Leo3 Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Yin Yin Teo4 Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Ivy Chung1 Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Boon Tong Goh5 Low Dimensional Materials Research Center, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Misni Misran4 Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, 50603, Malaysia
,
Toyoko Imae6 Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, 10607, Taiwan
,
Chia-Ching Chang7 Department of Biological Science and Technology, College of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 30068, Taiwan;8 Center for Intelligent Drug Systems and Smart Bio-Devices (IDSB), National Yang Ming Chiao Tung University, Hsinchu, 30050, Taiwan;9 Department of Electrophysics, National Yang Ming Chiao Tung University, Hsinchu, 30010, Taiwan;10 Institute of Physics, Academia Sinica, Nankang, Taipei, Taiwan;11 Taiwan-Malaysia Semiconductor and Biomedical Oversea Science and Technology Innovation Center, National Yang Ming Chiao Tung University, Hsinchu, 30010, TaiwanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3444-0894
ORCID Icon,
Lip Yong Chung2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Malaya, Kuala Lumpur, 50603, MalaysiaORCID Iconhttps://orcid.org/0000-0002-3596-768X
ORCID Icon &
Lik Voon Kiew1 Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia;7 Department of Biological Science and Technology, College of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 30068, TaiwanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-6855-9631
ORCID Icon show all
Pages 137-150 | Published online: 11 Jan 2022

Citations (9)

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Laura Deruyver, Clément Rigaut, Alejandro Gomez-Perez, Pierre Lambert, Benoit Haut & Jonathan Goole. (2023) In vitro Evaluation of Paliperidone Palmitate Loaded Cubosomes Effective for Nasal-to-Brain Delivery. International Journal of Nanomedicine 18, pages 1085-1106.
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Articles from other publishers (8)

Shamim Ashkezari, Maryam Sadat Abtahi, Zahra Sattari, Mohammad Tavakkoli Yaraki, Fatemeh Hosseini, Raheleh Inanloo Salehi, Elham Afzali, Saeedeh Hajihosseini & Neda Mousavi-Niri. (2023) Antibiotic and inorganic nanoparticles co-loaded into carboxymethyl chitosan-functionalized niosome: Synergistic enhanced antibacterial and anti-biofilm activities. Journal of Drug Delivery Science and Technology 83, pages 104386.
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Yedi Herdiana, Nasrul Wathoni, Dolih Gozali, Shaharum Shamsuddin & Muchtaridi Muchtaridi. (2023) Chitosan-Based Nano-Smart Drug Delivery System in Breast Cancer Therapy. Pharmaceutics 15:3, pages 879.
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Nika Kučuk, Mateja Primožič, Željko Knez & Maja Leitgeb. (2023) Sustainable Biodegradable Biopolymer-Based Nanoparticles for Healthcare Applications. International Journal of Molecular Sciences 24:4, pages 3188.
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Fatma Betül Arslan, Kıvılcım Öztürk, Ece Tavukçuoğlu, Süleyman Can Öztürk, Güneş Esendağlı & Sema Çalış. (2023) A novel combination for the treatment of small cell lung cancer: Active targeted irinotecan and stattic co-loaded PLGA nanoparticles. International Journal of Pharmaceutics 632, pages 122573.
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Sedat Ünal, Osman Doğan & Yeşim Aktaş. (2022) Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics. Beilstein Journal of Nanotechnology 13, pages 1393-1407.
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Matthias W. Laschke, Yuan Gu & Michael D. Menger. (2022) Replacement in angiogenesis research: Studying mechanisms of blood vessel development by animal-free in vitro, in vivo and in silico approaches. Frontiers in Physiology 13.
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Sara Karimifard, Niloufar Rezaei, Elham Jamshidifar, Shahryar Moradi Falah Langeroodi, Mohammadreza Abdihaji, Afsoun Mansouri, Mahshid Hosseini, Nima Ahmadkhani, Ziba Rahmati, Maryam Heydari, Massoud Vosough, Iman Akbarzadeh & Ebrahim Mostafavi. (2022) pH-Responsive Chitosan-Adorned Niosome Nanocarriers for Co-Delivery of Drugs for Breast Cancer Therapy. ACS Applied Nano Materials 5:7, pages 8811-8825.
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Kai Guo, Yixuan Liu, Min Ding, Qi Sun & Quazi T.H. Shubhra. (2022) Enhanced drug release from a pH-responsive nanocarrier can augment colon cancer treatment by blocking PD-L1 checkpoint and consuming tumor glucose. Materials & Design 219, pages 110824.
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