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International Journal of Nanomedicine Volume 8, 2013 - Issue
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Original Research

Nanoemulsions coated with alginate/chitosan as oral insulin delivery systems: preparation, characterization, and hypoglycemic effect in rats

Xiaoyang LiKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, China
,
Jianping QiKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, ChinaCorrespondence[email protected] [email protected]
,
Yunchang XieKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, China
,
Xi ZhangKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, China
,
Shunwen HuKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, China
,
Ying XuKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, China
,
Yi LuKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, China
&
Wei WuKey Laboratory of Smart Drug Delivery of Ministry of Education and People’s Liberation Army (PLA), School of Pharmacy, Fudan University, Shanghai, ChinaCorrespondence[email protected] [email protected]
 show all
Pages 23-32 | Published online: 28 Dec 2012

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Dinesh Kumar Sharma, Gurudutta Pattnaik & Amulyaratna Behera. (2023) Recent developments in nanoparticles for the treatment of diabetes. Journal of Drug Targeting 31:9, pages 908-919.
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Naima Faghmous, Djallel Bouzid, Marwa Boumaza, Asma Touati & Olivier Boyron. (2021) Optimization of chitosan-coated W/O/W multiple emulsion stabilized with Span 80 and Tween 80 using Box–Behnken design. Journal of Dispersion Science and Technology 42:10, pages 1566-1578.
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Zuxian Chen, Shangcong Han, Xiaotang Yang, Lisa Xu, Hong Qi, Guizhou Hao, Jie Cao, Yan Liang, Qingming Ma, Guimin Zhang & Yong Sun. (2020) Overcoming Multiple Absorption Barrier for Insulin Oral Delivery Using Multifunctional Nanoparticles Based on Chitosan Derivatives and Hyaluronic Acid. International Journal of Nanomedicine 15, pages 4877-4898.
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Shiming He, Zhongcheng Liu & Donggang Xu. (2019) Advance in oral delivery systems for therapeutic protein. Journal of Drug Targeting 27:3, pages 283-291.
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Marlene Lopes, Barbara Abrahim, Francisco Veiga, Raquel Seiça, Lucio Mendes Cabral, Philippe Arnaud, José Carlos Andrade & Antonio J. Ribeiro. (2017) Preparation methods and applications behind alginate-based particles. Expert Opinion on Drug Delivery 14:6, pages 769-782.
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Liyao Liu, Cuiping Zhou, Xuejun Xia & Yuling Liu. (2016) Self-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation. International Journal of Nanomedicine 11, pages 761-769.
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Khalid Al Rubeaan, Mohamed Rafiullah & Sanjay Jayavanth. (2016) Oral insulin delivery systems using chitosan-based formulation: a review. Expert Opinion on Drug Delivery 13:2, pages 223-237.
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Marlene A Lopes, Bárbara Abrahim-Vieira, Claudia Oliveira, Pedro Fonte, Alessandra M T Souza, Tammy Lira, Joana A D Sequeira, Carlos R Rodrigues, Lúcio M Cabral, Bruno Sarmento, Raquel Seiça, Francisco Veiga & António J Ribeiro. (2015) Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation. International Journal of Nanomedicine 10, pages 5865-5880.
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Articles from other publishers (10)

Mengna Zhang, Qiaoling Zhao, Yanan Lin, Haifeng Wang, Ruofan Shui, Shitong Wang, Lijun Ge, Yunyan Li, Gongshuai Song, Jinyan Gong, Haixing Wang, Xi Chen & Qing Shen. (2022) Fabrication and characterization of tea polyphenol W/O microemulsion‐based bioactive edible film for sustained release in fish floss preservation. Food Science & Nutrition 10:7, pages 2370-2380.
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Felipe Andrés Silva Jerez & Patricio Alejandro Oyarzún Cayo. (2021) Una visión actualizada sobre la síntesis, escalado y aplicaciones de las nanoemulsiones dobles. Entre ciencia e ingeniería 15:30, pages 30-40.
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Huifang Xie, Xin Ma, Wenbin Lin, Shiting Dong, Qiang Liu, Yi Chen & Qunyu Gao. (2021) Linear Dextrin as Potential Insulin Delivery System: Effect of Degree of Polymerization on the Physicochemical Properties of Linear Dextrin–Insulin Inclusion Complexes. Polymers 13:23, pages 4187.
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Mohammad Amin Raeisi Estabragh, Marzieh Sajadi Bami, Mandana Ohadi, Ibrahim M. Banat & Gholamreza Dehghannoudeh. (2021) Carrier‐Based Systems as Strategies for Oral Delivery of Therapeutic Peptides and Proteins: A Mini‐Review. International Journal of Peptide Research and Therapeutics 27:2, pages 1589-1596.
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Eliana B. Souto, Selma B. Souto, Joana R. Campos, Patricia Severino, Tatiana N. Pashirova, Lucia Y. Zakharova, Amélia M. Silva, Alessandra Durazzo, Massimo Lucarini, Angelo A. Izzo & Antonello Santini. (2019) Nanoparticle Delivery Systems in the Treatment of Diabetes Complications. Molecules 24:23, pages 4209.
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Lili Zhao, Mariusz Skwarczynski & Istvan Toth. (2019) Polyelectrolyte-Based Platforms for the Delivery of Peptides and Proteins. ACS Biomaterials Science & Engineering 5:10, pages 4937-4950.
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Shazia Mansoor, Pierre P. D. Kondiah, Yahya E. Choonara & Viness Pillay. (2019) Polymer-Based Nanoparticle Strategies for Insulin Delivery. Polymers 11:9, pages 1380.
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Taskeen Niaz, Saima Shabbir, Tayyaba Noor, Rashda Abbasi, Zulfiqar A. Raza & Muhammad Imran. (2018) Polyelectrolyte Multicomponent Colloidosomes Loaded with Nisin Z for Enhanced Antimicrobial Activity against Foodborne Resistant Pathogens. Frontiers in Microbiology 8.
Crossref
Ashish Kumar Agrawal, Kuldeep Kumar, Nitin Kumar Swarnakar, Varun Kushwah & Sanyog Jain. (2017) “Liquid Crystalline Nanoparticles”: Rationally Designed Vehicle To Improve Stability and Therapeutic Efficacy of Insulin Following Oral Administration. Molecular Pharmaceutics 14:6, pages 1874-1882.
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M.J. Ansari. (2015) Oral Delivery of Insulin for Treatment of Diabetes: Classical Challenges and Current Opportunities. Journal of Medical Sciences 15:5, pages 209-220.
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