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International Journal of Nanomedicine Volume 8, 2013 - Issue
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Original Research

High-efficiency liposomal encapsulation of a tyrosine kinase inhibitor leads to improved in vivo toxicity and tumor response profile

Rajesh Mukthavaram1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Pengfei Jiang1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Rohit Saklecha1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Dmitri Simberg3 Solid Tumor Therapeutics Program, Moores Cancer Center, UC San Diego, La Jolla, CA, USA;4 Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Denver, CO, USA
,
Ila Sri Bharati1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Natsuko Nomura1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Ying Chao1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Sandra Pastorino1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Sandeep C Pingle1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Valentina Fogal1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Wolf Wrasidlo1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA;2 Department of Neurosciences, Moores Cancer Center, UC San Diego, La Jolla, CA, USA
,
Milan Makale1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA;2 Department of Neurosciences, Moores Cancer Center, UC San Diego, La Jolla, CA, USACorrespondence[email protected]
&
Santosh Kesari1 Translational Neuro-Oncology Laboratories, Moores Cancer Center, UC San Diego, La Jolla, CA, USA;2 Department of Neurosciences, Moores Cancer Center, UC San Diego, La Jolla, CA, USACorrespondence[email protected]
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Pages 3991-4006 | Published online: 21 Oct 2013

Citations (7)

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Qingxia Fu, Jiancheng Wang & Hong Liu. (2020) Chemo-immune synergetic therapy of esophageal carcinoma: trastuzumab modified, cisplatin and fluorouracil co-delivered lipid–polymer hybrid nanoparticles. Drug Delivery 27:1, pages 1535-1543.
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Kai Sun, Yong Chang, Binbin Zhou, Xiaojin Wang & Lin Liu. (2017) Gold nanoparticles-based electrochemical method for the detection of protein kinase with a peptide-like inhibitor as the bioreceptor. International Journal of Nanomedicine 12, pages 1905-1915.
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Articles from other publishers (5)

Robin Lorenz, Jian Wu, Friedrich W. Herberg, Susan S. Taylor & Richard A. Engh. (2021) Drugging the Undruggable: How Isoquinolines and PKA Initiated the Era of Designed Protein Kinase Inhibitor Therapeutics. Biochemistry 60:46, pages 3470-3484.
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Max London & Eugenio Gallo. (2020) Critical role of EphA3 in cancer and current state of EphA3 drug therapeutics. Molecular Biology Reports 47:7, pages 5523-5533.
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Griffin Pauli, Wei-Lun Tang & Shyh-Dar Li. (2019) Development and Characterization of the Solvent-Assisted Active Loading Technology (SALT) for Liposomal Loading of Poorly Water-Soluble Compounds. Pharmaceutics 11:9, pages 465.
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Narendran Annadurai, Khushboo Agrawal, Petr Džubák, Marián Hajdúch & Viswanath Das. (2017) Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer’s disease. Cellular and Molecular Life Sciences 74:22, pages 4159-4169.
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Tuva R. Hope, Nathan S. White, Joshua Kuperman, Ying Chao, Ghiam Yamin, Hauke Bartch, Natalie M. Schenker-Ahmed, Rebecca Rakow-Penner, Robert Bussell, Natsuko Nomura, Santosh Kesari, Atle Bjørnerud & Anders M. Dale. (2016) Demonstration of Non-Gaussian Restricted Diffusion in Tumor Cells Using Diffusion Time-Dependent Diffusion-Weighted Magnetic Resonance Imaging Contrast. Frontiers in Oncology 6.
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