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International Journal of Nanomedicine Volume 9, 2014 - Issue
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Original Research

Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats

Cong Zhang1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan
,
Fan Peng1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan
,
Wei Liu1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan
,
Jiangling Wan1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan
,
Chunxi Wan1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan
,
Huibi Xu1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan;2 State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, People’s Republic of China
,
Christopher Waikei Lam2 State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, People’s Republic of ChinaCorrespondence[email protected]
&
Xiangliang Yang1 National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan;2 State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1049-1063 | Published online: 20 Feb 2014

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Tao Jiang, Shuangshuang Ma, Yangyang Shen, Yuwen Li, Ruirui Pan & Huaixin Xing. (2021) Topical anesthetic and pain relief using penetration enhancer and transcriptional transactivator peptide multi-decorated nanostructured lipid carriers. Drug Delivery 28:1, pages 478-486.
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Parisa Ghasemiyeh, Amir Azadi, Saeid Daneshamouz, Reza Heidari, Negar Azarpira & Soliman Mohammadi-Samani. (2019) Cyproterone acetate-loaded nanostructured lipid carriers: effect of particle size on skin penetration and follicular targeting. Pharmaceutical Development and Technology 24:7, pages 812-823.
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Ali Kermanizadeh, Leagh G Powell, Vicki Stone & Peter Møller. (2018) Nanodelivery systems and stabilized solid-drug nanoparticles for orally administered medicine: current landscape. International Journal of Nanomedicine 13, pages 7575-7605.
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Jia Liu, Hao Cheng, Le Han, Zhun Qiang, Xinwei Zhang, Wei Gao, Kun Zhao & Yangrong Song. (2018) Synergistic combination therapy of lung cancer using paclitaxel- and triptolide-coloaded lipid–polymer hybrid nanoparticles. Drug Design, Development and Therapy 12, pages 3199-3209.
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Yan Liang, Baocheng Tian, Jing Zhang, Keke Li, Lele Wang, Jingtian Han & Zimei Wu. (2017) Tumor-targeted polymeric nanostructured lipid carriers with precise ratiometric control over dual-drug loading for combination therapy in non-small-cell lung cancer. International Journal of Nanomedicine 12, pages 1699-1715.
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Jiying Yang, Zengjuan Ju & Shufang Dong. (2017) Cisplatin and paclitaxel co-delivered by folate-decorated lipid carriers for the treatment of head and neck cancer. Drug Delivery 24:1, pages 792-799.
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Peng Ji, Tong Yu, Ying Liu, Jie Jiang, Jie Xu, Ying Zhao, Yanna Hao, Yang Qiu, Wenming Zhao & Chao Wu. (2016) Naringenin-loaded solid lipid nanoparticles: preparation, controlled delivery, cellular uptake, and pulmonary pharmacokinetics. Drug Design, Development and Therapy 10, pages 911-925.
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Xiaojing Zhao, Qi Chen, Wei Liu, Yusang Li, Hebin Tang, Xuhan Liu & Xiangliang Yang. (2015) Codelivery of doxorubicin and curcumin with lipid nanoparticles results in improved efficacy of chemotherapy in liver cancer. International Journal of Nanomedicine 10, pages 257-270.
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Articles from other publishers (4)

Alok Kumar Mahor, Prem Prakash Singh, Rishikesh Gupta, Peeyush Bhardwaj, Priyanka Rathore, Ankita Kishore, Rohit Goyal, Neeraj Sharma, Jyoti Verma, Jessica M. Rosenholm & Kuldeep K. Bansal. (2023) Nanostructured Lipid Carriers for Improved Delivery of Therapeutics via the Oral Route. Journal of Nanotechnology 2023, pages 1-35.
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Alicia Fernandez-Fernandez, Romila Manchanda & Manisha Kumari. (2023) Lipid-engineered nanotherapeutics for cancer management. Frontiers in Pharmacology 14.
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Lin Wang, Zheyi Wang, Zhihua Yang, Kang Yang & Hongtao Yang. (2021) Study of the Active Components and Molecular Mechanism of Tripterygium wilfordii in the Treatment of Diabetic Nephropathy. Frontiers in Molecular Biosciences 8.
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Heba A. Ghanem, Ali M. Nasr, Tamer H. Hassan, Mahmoud M. Elkhoudary, Reem Alshaman, Abdullah Alattar & Shadeed Gad. (2021) Comprehensive Study of Atorvastatin Nanostructured Lipid Carriers through Multivariate Conceptualization and Optimization. Pharmaceutics 13:2, pages 178.
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