International Journal of Nanomedicine, Volume 9, Issue (2014)

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International Journal of Nanomedicine, Volume 9, Issue (2014)

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Review

Review Article
Nanotechnology-based drug delivery systems and herbal medicines: a review
Bruna Vidal Bonifácio, Patricia Bento da Silva, Matheus Aparecido dos Santos Ramos, Kamila Maria Silveira Negri, Taís Maria Bauab & Marlus Chorilli
Pages: 1-15
Published online: 09 Dec 2013
AbstractforNanotechnology-based drug delivery systems and herbal medicines: a review | Full Text | References | PDF (280 KB)
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Original Research

Article
Cyclosporine A-nanoparticles enhance the therapeutic benefit of adipose tissue-derived stem cell transplantation in a swine myocardial infarction model
Qiaoxiang Yin, Zhiyong Pei, Heng Wang & Yusheng Zhao
Pages: 17-26
Published online: 11 Dec 2013
AbstractforCyclosporine A-nanoparticles enhance the therapeutic benefit of adipose tissue-derived stem cell transplantation in a swine myocardial infarction model | Full Text | References | PDF (5 MB)
  • 64 Views
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Review

Review Article
Clinical implications of calcifying nanoparticles in dental diseases: a critical review
Mohammed S Alenazy & Hezekiah A Mosadomi
Pages: 27-31
Published online: 11 Dec 2013
AbstractforClinical implications of calcifying nanoparticles in dental diseases: a critical review | Full Text | References | PDF (227 KB)
  • 49 Views
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Original Research

Article
In vivo tomographic imaging with fluorescence and MRI using tumor-targeted dual-labeled nanoparticles
Yue Zhang, Bin Zhang, Fei Liu, Jianwen Luo & Jing Bai
Pages: 33-41
Published online: 16 Dec 2013
AbstractforIn vivo tomographic imaging with fluorescence and MRI using tumor-targeted dual-labeled nanoparticles | Full Text | References | PDF (1.9 MB)
  • 81 Views
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Open Access
Article
Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy
Srijayaprakash B Uppada, Terrianne Erickson, Luke Wojdyla, David N Moravec, Ziyuan Song, Jianjun Cheng & Neelu Puri
Pages: 43-53
Published online: 17 Dec 2013
AbstractforNovel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy | Full Text | References | PDF (2.3 MB)
  • 67 Views
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Open Access
Article
Development of high drug-loading nanomicelles targeting steroids to the brain
Sijia Zheng, Yanqi Xie, Yuan Li, Ling Li, Ning Tian, Wenbo Zhu, Guangmei Yan, Chuanbin Wu & Haiyan Hu
Pages: 55-66
Published online: 18 Dec 2013
AbstractforDevelopment of high drug-loading nanomicelles targeting steroids to the brain | Full Text | References | PDF (1.3 MB)
  • 65 Views
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Open Access
Article
Tumor-specific hyperthermia with aptamer-tagged superparamagnetic nanoparticles
Katarzyna Pala, Anna Serwotka, Filip Jeleń, Piotr Jakimowicz & Jacek Otlewski
Pages: 67-76
Published online: 18 Dec 2013
AbstractforTumor-specific hyperthermia with aptamer-tagged superparamagnetic nanoparticles | Full Text | References | PDF (3 MB)
  • 99 Views
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Review

Review Article
Fullerene–biomolecule conjugates and their biomedicinal applications
Xinlin Yang, Ali Ebrahimi, Jie Li & Quanjun Cui
Pages: 77-92
Published online: 18 Dec 2013
AbstractforFullerene–biomolecule conjugates and their biomedicinal applications | Full Text | References | PDF (1.8 MB)
  • 156 Views
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Original Research

Article
Photoprotective effects of apple peel nanoparticles
Devasier Bennet, Se Chan Kang, Jongback Gang & Sanghyo Kim
Pages: 93-108
Published online: 18 Dec 2013
AbstractforPhotoprotective effects of apple peel nanoparticles | Full Text | References | PDF (3.5 MB)
  • 138 Views
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Open Access
Article
Triterpene-loaded microemulsion using Coix lacryma-jobi seed extract as oil phase for enhanced antitumor efficacy: preparation and in vivo evaluation
Ding Qu, Junjie He, Congyan Liu, Jing Zhou & Yan Chen
Pages: 109-119
Published online: 19 Dec 2013
AbstractforTriterpene-loaded microemulsion using Coix lacryma-jobi seed extract as oil phase for enhanced antitumor efficacy: preparation and in vivo evaluation | Full Text | References | PDF (914.2 KB)
  • 113 Views
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Open Access
Article
Synthesis of silver nanoparticles with antibacterial activity using the lichen Parmotrema praesorediosum
Ropisah Mie, Mohd Wahid Samsudin, Laily B Din, Azizan Ahmad, Nazlina Ibrahim & Siti Noor Adnalizawati Adnan
Pages: 121-127
Published online: 19 Dec 2013
AbstractforSynthesis of silver nanoparticles with antibacterial activity using the lichen Parmotrema praesorediosum | Full Text | References | PDF (945.6 KB)
  • 311 Views
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Article
Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability
Waheed M Ibrahim, Abdullah H AlOmrani & Alaa Eldeen B Yassin
Pages: 129-144
Published online: 19 Dec 2013
AbstractforNovel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability | Full Text | References | PDF (1.5 MB)
  • 223 Views
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Article
Magnetic fluid hyperthermia enhances cytotoxicity of bortezomib in sensitive and resistant cancer cell lines
Merlis P Alvarez-Berríos, Amalchi Castillo, Carlos Rinaldi & Madeline Torres-Lugo
Pages: 145-153
Published online: 20 Dec 2013
AbstractforMagnetic fluid hyperthermia enhances cytotoxicity of bortezomib in sensitive and resistant cancer cell lines | Full Text | References | PDF (795 KB)
  • 56 Views
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Open Access
Article
Nitric oxide-loaded echogenic liposomes for treatment of vasospasm following subarachnoid hemorrhage
Hyunggun Kim, George L Britton, Tao Peng, Christy K Holland, David D McPherson & Shao-Ling Huang
Pages: 155-165
Published online: 21 Dec 2013
AbstractforNitric oxide-loaded echogenic liposomes for treatment of vasospasm following subarachnoid hemorrhage | Full Text | References | PDF (1.9 MB)
  • 83 Views
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Open Access
Article
3D conductive nanocomposite scaffold for bone tissue engineering
Aref Shahini, Mostafa Yazdimamaghani, Kenneth J Walker, Margaret A Eastman, Hamed Hatami-Marbini, Brenda J Smith, John L Ricci, Sundar V Madihally, Daryoosh Vashaee & Lobat Tayebi
Pages: 167-181
Published online: 24 Dec 2013
Abstractfor3D conductive nanocomposite scaffold for bone tissue engineering | Full Text | References | PDF (2.4 MB)
  • 304 Views
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Open Access
Article
Polycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering
Manjunath Srinivas Kamath, Shiek SSJ Ahmed, M Dhanasekaran & S Winkins Santosh
Pages: 183-195
Published online: 23 Dec 2013
AbstractforPolycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering | Full Text | References | PDF (4.1 MB)
  • 158 Views
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Article
Novel tumor-targeting, self-assembling peptide nanofiber as a carrier for effective curcumin delivery
Jianfeng Liu, Jinjian Liu, Hongyan Xu, Yumin Zhang, Liping Chu, Qingfen Liu, Naling Song & Cuihong Yang
Pages: 197-207
Published online: 24 Dec 2013
AbstractforNovel tumor-targeting, self-assembling peptide nanofiber as a carrier for effective curcumin delivery | Full Text | References | PDF (3.6 MB)
  • 166 Views
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Review

Review Article
First line treatment of advanced non-small-cell lung cancer – specific focus on albumin bound paclitaxel
Neha Gupta, Hassan Hatoum & Grace K Dy
Pages: 209-221
Published online: 24 Dec 2013
AbstractforFirst line treatment of advanced non-small-cell lung cancer – specific focus on albumin bound paclitaxel | Full Text | References | PDF (1.1 MB)
  • 165 Views
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Original Research

Article
Interaction between nanoparticles generated by zinc chloride treatment and oxidative responses in rat liver
Inès Azzouz, Hamdi Trabelsi, Amel Hanini, Soumaya Ferchichi, Olfa Tebourbi, Mohsen Sakly & Hafedh Abdelmelek
Pages: 223-229
Published online: 27 Dec 2013
AbstractforInteraction between nanoparticles generated by zinc chloride treatment and oxidative responses in rat liver | Full Text | References | PDF (1 MB)
  • 49 Views
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Open Access
Article
An efficient Trojan delivery of tetrandrine by poly(N-vinylpyrrolidone)-block-poly(ε-caprolactone) (PVP-b-PCL) nanoparticles shows enhanced apoptotic induction of lung cancer cells and inhibition of its migration and invasion
Huae Xu, Zhibo Hou, Hao Zhang, Hui Kong, Xiaolin Li, Hong Wang & Weiping Xie
Pages: 231-242
Published online: 27 Dec 2013
AbstractforAn efficient Trojan delivery of tetrandrine by poly(N-vinylpyrrolidone)-block-poly(ε-caprolactone) (PVP-b-PCL) nanoparticles shows enhanced apoptotic induction of lung cancer cells and inhibition of its migration and invasion | Full Text | References | PDF (3.2 MB)
  • 82 Views
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Article
Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles
Lulu Cai, Neng Qiu, Mingli Xiang, Rongsheng Tong, Junfeng Yan, Lin He, Jianyou Shi, Tao Chen, Jiaolin Wen, Wenwen Wang & Lijuan Chen
Pages: 243-255
Published online: 27 Dec 2013
AbstractforImproving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles | Full Text | References | PDF (2.4 MB)
  • 82 Views
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Open Access
Article
Greater fibroblast proliferation on an ultrasonicated ZnO/PVC nanocomposite material
Paul M Maschhoff, Benjamin M Geilich & Thomas J Webster
Pages: 257-263
Published online: 28 Dec 2013
AbstractforGreater fibroblast proliferation on an ultrasonicated ZnO/PVC nanocomposite material | Full Text | References | PDF (821.4 KB)
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Article
Cytotoxicity and apoptosis induced by nanobacteria in human breast cancer cells
Ming-jun Zhang, Sheng-nan Liu, Ge Xu, Ya-nan Guo, Jian-nan Fu & De-chun Zhang
Pages: 265-271
Published online: 30 Dec 2013
AbstractforCytotoxicity and apoptosis induced by nanobacteria in human breast cancer cells | Full Text | References | PDF (2.7 MB)
  • 77 Views
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Article
Superparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors
Maxim A Shevtsov, Boris P Nikolaev, Ludmila Y Yakovleva, Yaroslav Y Marchenko, Anatolii V Dobrodumov, Anastasiya L Mikhrina, Marina G Martynova, Olga A Bystrova, Igor V Yakovenko & Alexander M Ischenko
Pages: 273-287
Published online: 03 Jan 2014
AbstractforSuperparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors | Full Text | References | PDF (3.8 MB)
  • 130 Views
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Open Access
Article
Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule
Sang Gon Lee, Jae Han Jeong, Kyung Min Lee, Kyu Ho Jeong, Huisuk Yang, Miroo Kim, Hyungil Jung, Sangkil Lee & Young Wook Choi
Pages: 289-299
Published online: 31 Dec 2013
AbstractforNanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule | Full Text | References | PDF (2.2 MB)
  • 226 Views
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Open Access
Article
Anti-obesity efficacy of nanoemulsion oleoresin capsicum in obese rats fed a high-fat diet
Joo-Yeon Kim, Mak-Soon Lee, Sunyoon Jung, Hyunjin Joo, Chong-Tai Kim, In-Hwan Kim, Sangjin Seo, Soojung Oh & Yangha Kim
Pages: 301-310
Published online: 03 Jan 2014
AbstractforAnti-obesity efficacy of nanoemulsion oleoresin capsicum in obese rats fed a high-fat diet | Full Text | References | PDF (947.9 KB)
  • 116 Views
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Open Access
Article
Local sustained delivery of acetylsalicylic acid via hybrid stent with biodegradable nanofibers reduces adhesion of blood cells and promotes reendothelialization of the denuded artery
Cheng-Hung Lee, Yu-Huang Lin, Shang-Hung Chang, Chun-Der Tai, Shih-Jung Liu, Yen Chu, Chao-Jan Wang, Ming-Yi Hsu, Hung Chang, Gwo-Jyh Chang, Kuo-Chun Hung, Ming-Jer Hsieh, Fen-Chiung Lin, I-Chang Hsieh, Ming-Shien Wen & Yenlin Huang
Pages: 311-326
Published online: 06 Jan 2014
AbstractforLocal sustained delivery of acetylsalicylic acid via hybrid stent with biodegradable nanofibers reduces adhesion of blood cells and promotes reendothelialization of the denuded artery | Full Text | References | PDF (4.6 MB)
  • 61 Views
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Open Access
Article
Evaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection
Zhiwen Yang, Meiwan Chen, Muhua Yang, Jian Chen, Weijun Fang & Ping Xu
Pages: 327-336
Published online: 06 Jan 2014
AbstractforEvaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection | Full Text | References | PDF (798.9 KB)
  • 165 Views
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Open Access
Article
Umbilical cord mesenchymal stem cells labeled with multimodal iron oxide nanoparticles with fluorescent and magnetic properties: application for in vivo cell tracking
Tatiana T Sibov, Lorena F Pavon, Liza A Miyaki, Javier B Mamani, Leopoldo P Nucci, Larissa T Alvarim, Paulo H Silveira, Luciana C Marti & LF Gamarra
Pages: 337-350
Published online: 08 Jan 2014
AbstractforUmbilical cord mesenchymal stem cells labeled with multimodal iron oxide nanoparticles with fluorescent and magnetic properties: application for in vivo cell tracking | Full Text | References | PDF (5.3 MB)
  • 53 Views
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Open Access
Article
Novel kojic acid-polymer-based magnetic nanocomposites for medical applications
Samer Hasan Hussein-Al-Ali, Mohamed Ezzat El Zowalaty, Mohd Zobir Hussein, Maznah Ismail, Dena Dorniani & Thomas J Webster
Pages: 351-362
Published online: 07 Jan 2014
AbstractforNovel kojic acid-polymer-based magnetic nanocomposites for medical applications | Full Text | References | PDF (2.5 MB)
  • 133 Views
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Open Access
Article
Ginkgo biloba: a natural reducing agent for the synthesis of cytocompatible graphene
Sangiliyandi Gurunathan, Jae Woong Han, Jung Hyun Park, Vasuki Eppakayala & Jin-Hoi Kim
Pages: 363-377
Published online: 07 Jan 2014
AbstractforGinkgo biloba: a natural reducing agent for the synthesis of cytocompatible graphene | Full Text | References | PDF (2.3 MB)
  • 113 Views
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Article
Rapid green synthesis of silver nanoparticles from Chrysanthemum indicum L and its antibacterial and cytotoxic effects: an in vitro study
Selvaraj Arokiyaraj, Mariadhas Valan Arasu, Savariar Vincent, Nyayirukannaian Udaya Prakash, Seong Ho Choi, Young-Kyoon Oh, Ki Choon Choi & Kyoung Hoon Kim
Pages: 379-388
Published online: 07 Jan 2014
AbstractforRapid green synthesis of silver nanoparticles from Chrysanthemum indicum L and its antibacterial and cytotoxic effects: an in vitro study | Full Text | References | PDF (1.9 MB)
  • 423 Views
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Article
Preparation and efficacy of Newcastle disease virus DNA vaccine encapsulated in chitosan nanoparticles
Kai Zhao, Yang Zhang, Xiaoyan Zhang, Wei Li, Ci Shi, Chen Guo, Chunxiao Dai, Qian Chen, Zheng Jin, Yan Zhao, Hongyu Cui & Yunfeng Wang
Pages: 389-402
Published online: 07 Jan 2014
AbstractforPreparation and efficacy of Newcastle disease virus DNA vaccine encapsulated in chitosan nanoparticles | Full Text | References | PDF (3 MB)
  • 152 Views
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Article
Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells
Maryam Tahmasebi Mirgani, Benedetta Isacchi, Majid Sadeghizadeh, Fabio Marra, Anna Rita Bilia, Seyed Javad Mowla, Farhood Najafi & Esmael Babaei
Pages: 403-417
Published online: 13 Jan 2014
AbstractforDendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells | Full Text | References | PDF (1.9 MB)
  • 143 Views
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Open Access
Article
An efficient nonviral gene-delivery vector based on hyperbranched cationic glycogen derivatives
Xuan Liang, Xianyue Ren, Zhenzhen Liu, Yingliang Liu, Jue Wang, Jingnan Wang, Li-Ming Zhang, David YB Deng, Daping Quan & Liqun Yang
Pages: 419-435
Published online: 31 Jan 2014
AbstractforAn efficient nonviral gene-delivery vector based on hyperbranched cationic glycogen derivatives | Full Text | References | PDF (4.4 MB)
  • 62 Views
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Open Access
Article
Curcumin and 5-Fluorouracil-loaded, folate- and transferrin-decorated polymeric magnetic nanoformulation: a synergistic cancer therapeutic approach, accelerated by magnetic hyperthermia
Sivakumar Balasubramanian, Aswathy Ravindran Girija, Yutaka Nagaoka, Seiki Iwai, Masashi Suzuki, Venugopal Kizhikkilot, Yasuhiko Yoshida, Toru Maekawa & Sakthikumar Dasappan Nair
Pages: 437-459
Published online: 09 Jan 2014
AbstractforCurcumin and 5-Fluorouracil-loaded, folate- and transferrin-decorated polymeric magnetic nanoformulation: a synergistic cancer therapeutic approach, accelerated by magnetic hyperthermia | Full Text | References | PDF (7.9 MB)
  • 122 Views
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Article
Short communication: selective cytotoxicity of curcumin on osteosarcoma cells compared to healthy osteoblasts
Run Chang, Linlin Sun & Thomas J Webster
Pages: 461-465
Published online: 10 Jan 2014
AbstractforShort communication: selective cytotoxicity of curcumin on osteosarcoma cells compared to healthy osteoblasts | Full Text | References | PDF (223 KB)
  • 96 Views
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Review

Review Article
Targeted therapy using nanotechnology: focus on cancer
Vanna Sanna, Nicolino Pala & Mario Sechi
Pages: 467-483
Published online: 15 Jan 2014
AbstractforTargeted therapy using nanotechnology: focus on cancer | Full Text | References | PDF (2.7 MB)
  • 1007 Views
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Original Research

Article
Analyzing the behavior of a porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite for healing of bone defects
Yan Xiong, Cheng Ren, Bin Zhang, Hongsheng Yang, Yun Lang, Li Min, Wenli Zhang, Fuxing Pei, Yonggang Yan, Hong Li, Anchun Mo, Chongqi Tu & Hong Duan
Pages: 485-494
Published online: 13 Jan 2014
AbstractforAnalyzing the behavior of a porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite for healing of bone defects | Full Text | References | PDF (1.9 MB)
  • 122 Views
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Open Access
Article
Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake
Hyun-Jong Cho, Jin Woo Park, In-Soo Yoon & Dae-Duk Kim
Pages: 495-504
Published online: 13 Jan 2014
AbstractforSurface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake | Full Text | References | PDF (1.3 MB)
  • 257 Views
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Open Access
Article
Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration
Qingyuan Lv, Xianyi Li, Baode Shen, He Xu, Chengying Shen, Ling Dai, Jinxia Bai, Hailong Yuan & Jin Han
Pages: 505-515
Published online: 15 Jan 2014
AbstractforApplication of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration | Full Text | References | PDF (1.4 MB)
  • 65 Views
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Open Access
Article
Photothermal therapy of cancer cells using novel hollow gold nanoflowers
Jing Han, Jinru Li, Wenfeng Jia, Liangming Yao, Xiaoqin Li, Long Jiang & Yong Tian
Pages: 517-526
Published online: 16 Jan 2014
AbstractforPhotothermal therapy of cancer cells using novel hollow gold nanoflowers | Full Text | References | PDF (3 MB)
  • 100 Views
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Open Access
Article
Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
Heshu Sulaiman Rahman, Abdullah Rasedee, Ahmad Bustamam Abdul, Nazariah Allaudin Zeenathul, Hemn Hassan Othman, Swee Keong Yeap, Chee Wun How & Wan Abd Ghani Wan Nor Hafiza
Pages: 527-538
Published online: 16 Jan 2014
AbstractforZerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line | Full Text | References | PDF (4.8 MB)
  • 83 Views
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Article
Formulation development and optimization of palm kernel oil esters-based nanoemulsions containing sodium diclofenac
Malahat Rezaee, Mahiran Basri, Raja Noor Zaliha Raja Abdul Rahman, Abu Bakar Salleh, Naz Chaibakhsh & Roghayeh Abedi Karjiban
Pages: 539-548
Published online: 17 Jan 2014
AbstractforFormulation development and optimization of palm kernel oil esters-based nanoemulsions containing sodium diclofenac | Full Text | References | PDF (2 MB)
  • 109 Views
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Article
Synthesis, characterization, controlled release, and antibacterial studies of a novel streptomycin chitosan magnetic nanoantibiotic
Samer Hasan Hussein-Al-Ali, Mohamed Ezzat El Zowalaty, Mohd Zobir Hussein, Maznah Ismail & Thomas J Webster
Pages: 549-557
Published online: 16 Jan 2014
AbstractforSynthesis, characterization, controlled release, and antibacterial studies of a novel streptomycin chitosan magnetic nanoantibiotic | Full Text | References | PDF (1.1 MB)
  • 188 Views
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Corrigendum

Correction
Biodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent [Corrigendum]
Page: 559
Published online: 20 Jan 2014
CitationforBiodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent [Corrigendum] | Full Text | PDF (91.4 KB)
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Original Research

Article
Steric environment around acetylcholine head groups of bolaamphiphilic nanovesicles influences the release rate of encapsulated compounds
Avital Stern, Matteo Guidotti, Eleonora Shaubi, Mary Popov, Charles Linder, Eliahu Heldman & Sarina Grinberg
Pages: 561-574
Published online: 20 Jan 2014
AbstractforSteric environment around acetylcholine head groups of bolaamphiphilic nanovesicles influences the release rate of encapsulated compounds | Full Text | References | PDF (890.2 KB)
  • 55 Views
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Open Access
Article
Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier
Mayank Chaturvedi, Yves Molino, Bojja Sreedhar, Michel Khrestchatisky & Leszek Kaczmarek
Pages: 575-588
Published online: 20 Jan 2014
AbstractforTissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier | Full Text | References | PDF (2.3 MB)
  • 101 Views
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Review

Review Article
Overview of the role of nanotechnological innovations in the detection and treatment of solid tumors
Derusha Frank, Charu Tyagi, Lomas Tomar, Yahya E Choonara, Lisa C du Toit, Pradeep Kumar, Clement Penny & Viness Pillay
Pages: 589-613
Published online: 22 Jan 2014
AbstractforOverview of the role of nanotechnological innovations in the detection and treatment of solid tumors | Full Text | References | PDF (2.2 MB)
  • 69 Views
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Original Research

Article
Injectable thermosensitive hydrogel composite with surface-functionalized calcium phosphate as raw materials
RangRang Fan, XiaoHui Deng, LiangXue Zhou, Xiang Gao, Min Fan, YueLong Wang & Gang Guo
Pages: 615-626
Published online: 21 Jan 2014
AbstractforInjectable thermosensitive hydrogel composite with surface-functionalized calcium phosphate as raw materials | Full Text | References | PDF (2.2 MB)
  • 54 Views
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Open Access
Article
Enhancement of immunogenicity and efficacy of a plasmid DNA rabies vaccine by nanoformulation with a fourth-generation amine-terminated poly(ether imine) dendrimer
Padinjaremattathil Thankappan Ullas, Shampur Narayan Madhusudana, Anita Desai, Bhadravathi Kenchappa Chandrasekhar Sagar, Govindasamy Jayamurugan, Yamajala Bhaskara Rama Durga Rajesh & Narayanaswami Jayaraman
Pages: 627-634
Published online: 28 Jan 2014
AbstractforEnhancement of immunogenicity and efficacy of a plasmid DNA rabies vaccine by nanoformulation with a fourth-generation amine-terminated poly(ether imine) dendrimer | Full Text | References | PDF (615.3 KB)
  • 73 Views
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Open Access
Article
RETRACTED ARTICLE: Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models
Carlotta Marianecci, Federica Rinaldi, Luisa Di Marzio, Marica Mastriota, Stefano Pieretti, Christian Celia, Donatella Paolino, Michelangelo Iannone, Massimo Fresta & Maria Carafa
Pages: 635-651
Published online: 24 Jan 2014
AbstractforRETRACTED ARTICLE: Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models | PDF (2.4 MB)
  • 43 Views
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Article
Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies
Mateusz Legut, Dominik Lipka, Nina Filipczak, Adriana Piwoni, Arkadiusz Kozubek & Jerzy Gubernator
Pages: 653-668
Published online: 23 Jan 2014
AbstractforAnacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies | Full Text | References | PDF (533.1 KB)
  • 94 Views
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Article
Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis
Yong-Tai Zhang, Li-Na Shen, Ji-Hui Zhao & Nian-Ping Feng
Pages: 669-678
Published online: 23 Jan 2014
AbstractforEvaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis | Full Text | References | PDF (1.1 MB)
  • 120 Views
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Open Access
Article
Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs
Basavaraj Binjawadagi, Varun Dwivedi, Cordelia Manickam, Kang Ouyang, Yun Wu, Ly James Lee, Jordi B Torrelles & Gourapura J Renukaradhya
Pages: 679-694
Published online: 24 Jan 2014
AbstractforAdjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs | Full Text | References | PDF (1 MB)
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Article
Optimized synthesis of glycyrrhetinic acid-modified chitosan 5-fluorouracil nanoparticles and their characteristics
Mingrong Cheng, Houxiang Chen, Yong Wang, Hongzhi Xu, Bing He, Jiang Han & Zhiping Zhang
Pages: 695-710
Published online: 24 Jan 2014
AbstractforOptimized synthesis of glycyrrhetinic acid-modified chitosan 5-fluorouracil nanoparticles and their characteristics | Full Text | References | PDF (3.9 MB)
  • 80 Views
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Review

Review Article
Nanoparticles for multimodal in vivo imaging in nanomedicine
Jaehong Key & James F Leary
Pages: 711-726
Published online: 29 Jan 2014
AbstractforNanoparticles for multimodal in vivo imaging in nanomedicine | Full Text | References | PDF (4.2 MB)
  • 287 Views
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Original Research

Article
Biodegradable and thermosensitive micelles inhibit ischemia-induced postoperative peritoneal adhesion
Qinjie Wu, Ling Li, Ning Wang, Xiang Gao, Bilan Wang, Xinyu Liu, Zhiyong Qian, Yuquan Wei & Changyang Gong
Pages: 727-734
Published online: 05 Feb 2014
AbstractforBiodegradable and thermosensitive micelles inhibit ischemia-induced postoperative peritoneal adhesion | Full Text | References | PDF (3.6 MB)
  • 55 Views
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Article
Comparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery
Susan Hua
Pages: 735-744
Published online: 30 Jan 2014
AbstractforComparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery | Full Text | References | PDF (488.9 KB)
  • 292 Views
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Article
Enhanced antitumor activity of realgar mediated by milling it to nanosize
Ye Tian, Xiaobo Wang, Ronggang Xi, Weisan Pan, Shuang Jiang, Zhao Li, Yu Zhao, Guanghui Gao & Dan Liu
Pages: 745-757
Published online: 31 Jan 2014
AbstractforEnhanced antitumor activity of realgar mediated by milling it to nanosize | Full Text | References | PDF (2 MB)
  • 64 Views
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Article
Single-walled carbon nanohorn (SWNH) aggregates inhibited proliferation of human liver cell lines and promoted apoptosis, especially for hepatoma cell lines
Jinqian Zhang, Qiang Sun, Jian Bo, Rui Huang, Mengran Zhang, Zhenglin Xia, Lili Ju & Guoan Xiang
Pages: 759-773
Published online: 04 Feb 2014
AbstractforSingle-walled carbon nanohorn (SWNH) aggregates inhibited proliferation of human liver cell lines and promoted apoptosis, especially for hepatoma cell lines | Full Text | References | PDF (5.4 MB)
  • 58 Views
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Article
Role of nanostructured gold surfaces on monocyte activation and Staphylococcus epidermidis biofilm formation
Sara Svensson, Magnus Forsberg, Mats Hulander, Forugh Vazirisani, Anders Palmquist, Jukka Lausmaa, Peter Thomsen & Margarita Trobos
Pages: 775-794
Published online: 07 Feb 2014
AbstractforRole of nanostructured gold surfaces on monocyte activation and Staphylococcus epidermidis biofilm formation | Full Text | References | PDF (7.7 MB)
  • 58 Views
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Review

Review Article
Nanoscale drug delivery systems and the blood–brain barrier
Renad Alyautdin, Igor Khalin, Mohd Ismail Nafeeza, Muhammad Huzaimi Haron & Dmitry Kuznetsov
Pages: 795-811
Published online: 07 Feb 2014
AbstractforNanoscale drug delivery systems and the blood–brain barrier | Full Text | References | PDF (325.6 KB)
  • 303 Views
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Original Research

Article
Development of Yersinia pestis F1 antigen-loaded microspheres vaccine against plague
Shih-shiung Huang, I-Hsun Li, Po-da Hong & Ming-kung Yeh
Pages: 813-822
Published online: 07 Feb 2014
AbstractforDevelopment of Yersinia pestis F1 antigen-loaded microspheres vaccine against plague | Full Text | References | PDF (674.6 KB)
  • 119 Views
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Article
Cognitive deficits and decreased locomotor activity induced by single-walled carbon nanotubes and neuroprotective effects of ascorbic acid
Xudong Liu, Yuchao Zhang, Jinquan Li, Dong Wang, Yang Wu, Yan Li, Zhisong Lu, Samuel CT Yu, Rui Li & Xu Yang
Pages: 823-839
Published online: 11 Feb 2014
AbstractforCognitive deficits and decreased locomotor activity induced by single-walled carbon nanotubes and neuroprotective effects of ascorbic acid | Full Text | References | PDF (5.1 MB)
  • 87 Views
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Article
Structure–property relationships in hybrid dental nanocomposite resins containing monofunctional and multifunctional polyhedral oligomeric silsesquioxanes
Weiguo Wang, Xiang Sun, Li Huang, Yu Gao, Jinghao Ban, Lijuan Shen & Jihua Chen
Pages: 841-852
Published online: 10 Feb 2014
AbstractforStructure–property relationships in hybrid dental nanocomposite resins containing monofunctional and multifunctional polyhedral oligomeric silsesquioxanes | Full Text | References | PDF (3 MB)
  • 73 Views
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Article
Flower-shaped ZnO nanoparticles synthesized by a novel approach at near-room temperatures with antibacterial and antifungal properties
Mohd Farhan Khan, M Hameedullah, Akhter H Ansari, Ejaz Ahmad, MB Lohani, Rizwan Hasan Khan, M Mezbaul Alam, Wasi Khan, Fohad Mabood Husain & Iqbal Ahmad
Pages: 853-864
Published online: 10 Feb 2014
AbstractforFlower-shaped ZnO nanoparticles synthesized by a novel approach at near-room temperatures with antibacterial and antifungal properties | Full Text | References | PDF (3.4 MB)
  • 201 Views
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Letter

Letter
MRI-based identification of undifferentiated cells: looking at the two faces of Janus
Ciprian Tomuleasa, Ioan Stefan Florian, Cristian Berce, Alexandru Irimie, Ioana Berindan-Neagoe & Andrei Cucuianu
Pages: 865-866
Published online: 11 Feb 2014
CitationforMRI-based identification of undifferentiated cells: looking at the two faces of Janus | Full Text | References | PDF (128 KB)
  • 39 Views
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Original Research

Article
Development and characterization of biocompatible isotropic and anisotropic oil-in-water colloidal dispersions as a new delivery system for methyl dihydrojasmonate antitumor drug
Gisela Bevilacqua Rolfsen Ferreira da Silva, Maria Virginia Scarpa, Gustavo Rossanezi, Eryvaldo Socrates Tabosa do Egito & Anselmo Gomes de Oliveira
Pages: 867-876
Published online: 11 Feb 2014
AbstractforDevelopment and characterization of biocompatible isotropic and anisotropic oil-in-water colloidal dispersions as a new delivery system for methyl dihydrojasmonate antitumor drug | Full Text | References | PDF (1.8 MB)
  • 49 Views
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Article
Novel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug-delivery system
Tatiana G Ribeiro, Miguel A Chávez-Fumagalli, Diogo G Valadares, Juçara R França, Lívia B Rodrigues, Mariana C Duarte, Paula S Lage, Pedro H R Andrade, Daniela P Lage, Leonardo V Arruda, Daniel R Abánades, Lourena E Costa, Vivian T Martins, Carlos AP Tavares, Rachel O Castilho, Eduardo AF Coelho & André AG Faraco
Pages: 877-890
Published online: 14 Feb 2014
AbstractforNovel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug-delivery system | Full Text | References | PDF (2.1 MB)
  • 168 Views
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Article
Virgin olive oil blended polyurethane micro/nanofibers ornamented with copper oxide nanocrystals for biomedical applications
Touseef Amna, M Shamshi Hassan, Jieun Yang, Myung-Seob Khil, Ki-Duk Song, Jae-Don Oh & Inho Hwang
Pages: 891-898
Published online: 13 Feb 2014
AbstractforVirgin olive oil blended polyurethane micro/nanofibers ornamented with copper oxide nanocrystals for biomedical applications | Full Text | References | PDF (2.2 MB)
  • 127 Views
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Review

Review Article
Nanoparticles in relation to peptide and protein aggregation
Masihuz Zaman, Ejaz Ahmad, Atiyatul Qadeer, Gulam Rabbani & Rizwan Hasan Khan
Pages: 899-912
Published online: 12 Feb 2014
AbstractforNanoparticles in relation to peptide and protein aggregation | Full Text | References | PDF (804.1 KB)
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Original Research

Article
Self-microemulsifying drug-delivery system for improved oral bioavailability of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol: preparation and evaluation
Shuang Cai, Cai-Hong Shi, Xiangrong Zhang, Xiaojiao Tang, Hao Suo, Li Yang & Yuqing Zhao
Pages: 913-920
Published online: 12 Feb 2014
AbstractforSelf-microemulsifying drug-delivery system for improved oral bioavailability of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol: preparation and evaluation | Full Text | References | PDF (979 KB)
  • 38 Views
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Article
GE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation
Liang Cheng, Fa-Zhen Huang, Li-Fang Cheng, Ya-Qin Zhu, Qing Hu, Ling Li, Lin Wei & Da-Wei Chen
Pages: 921-935
Published online: 12 Feb 2014
AbstractforGE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation | Full Text | References | PDF (2.2 MB)
  • 172 Views
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Article
Fabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity
Chandravilas Keshvan Prashant, Madhusudan Bhat, Sandeep Kumar Srivastava, Ankit Saxena, Manoj Kumar, Amar Singh, Mohammed Samim, Farhan Jalees Ahmad & Amit Kumar Dinda
Pages: 937-950
Published online: 12 Feb 2014
AbstractforFabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity | Full Text | References | PDF (3.4 MB)
  • 65 Views
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Article
The use of nanoencapsulation to decrease human skin irritation caused by capsaicinoids
Renata V Contri, Luiza A Frank, Moacir Kaiser, Adriana R Pohlmann & Silvia S Guterres
Pages: 951-962
Published online: 12 Feb 2014
AbstractforThe use of nanoencapsulation to decrease human skin irritation caused by capsaicinoids | Full Text | References | PDF (777.5 KB)
  • 99 Views
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Article
In vitro transfection of bone marrow-derived dendritic cells with TATp-liposomes
Juan Sebastián Pappalardo, Cecilia A Langellotti, Sebastián Di Giacomo, Valeria Olivera, Valeria Quattrocchi, Patricia I Zamorano, William C Hartner, Tatyana S Levchenko & Vladimir P Torchilin
Pages: 963-973
Published online: 13 Feb 2014
AbstractforIn vitro transfection of bone marrow-derived dendritic cells with TATp-liposomes | Full Text | References | PDF (1.8 MB)
  • 51 Views
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Article
In vivo and in vitro investigations of a nanostructured coating material – a preclinical study
Martin Adam, Cornelia Ganz, Weiguo Xu, Hamid-Reza Sarajian, Werner Götz & Thomas Gerber
Pages: 975-984
Published online: 14 Feb 2014
AbstractforIn vivo and in vitro investigations of a nanostructured coating material – a preclinical study | Full Text | References | PDF (4.5 MB)
  • 48 Views
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Article
The therapeutic effect of monocyte chemoattractant protein-1 delivered by an electrospun scaffold for hyperglycemia and nephrotic disorders
Cai Yong, Zhengxin Wang, Xing Zhang, Xiaomin Shi, Zhijia Ni, Hong Fu, Guoshan Ding, Zhiren Fu & Hao Yin
Pages: 985-993
Published online: 17 Feb 2014
AbstractforThe therapeutic effect of monocyte chemoattractant protein-1 delivered by an electrospun scaffold for hyperglycemia and nephrotic disorders | Full Text | References | PDF (1.1 MB)
  • 41 Views
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Article
Enrichment of breast cancer stem-like cells by growth on electrospun polycaprolactone-chitosan nanofiber scaffolds
Jennifer Sims-Mourtada, Rohina A Niamat, Shani Samuel, Chris Eskridge & Eric B Kmiec
Pages: 995-1003
Published online: 19 Feb 2014
AbstractforEnrichment of breast cancer stem-like cells by growth on electrospun polycaprolactone-chitosan nanofiber scaffolds | Full Text | References | PDF (2.4 MB)
  • 205 Views
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Review

Review Article
Nanotherapeutics in the EU: an overview on current state and future directions
Anita Hafner, Jasmina Lovrić, Gorana Perina Lakoš & Ivan Pepić
Pages: 1005-1023
Published online: 19 Feb 2014
AbstractforNanotherapeutics in the EU: an overview on current state and future directions | Full Text | References | PDF (1.1 MB)
  • 572 Views
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Review Article
Nanodrugs: pharmacokinetics and safety
Satomi Onoue, Shizuo Yamada & Hak-Kim Chan
Pages: 1025-1037
Published online: 20 Feb 2014
AbstractforNanodrugs: pharmacokinetics and safety | Full Text | References | PDF (402.4 KB)
  • 539 Views
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Original Research

Article
Subtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications
Chuang Chen, Jing-Ping Yuan, Wen Wei, Yi Tu, Feng Yao, Xue-Qin Yang, Jin-Zhong Sun, Sheng-Rong Sun & Yan Li
Pages: 1039-1048
Published online: 21 Feb 2014
AbstractforSubtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications | Full Text | References | PDF (1.3 MB)
  • 55 Views
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Article
Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats
Cong Zhang, Fan Peng, Wei Liu, Jiangling Wan, Chunxi Wan, Huibi Xu, Christopher Waikei Lam & Xiangliang Yang
Pages: 1049-1063
Published online: 20 Feb 2014
AbstractforNanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats | Full Text | References | PDF (2.5 MB)
  • 112 Views
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Article
In vivo enhancement of anticancer therapy using bare or chemotherapeutic drug-bearing nanodiamond particles
Yingqi Li, Yaoli Tong, Ruixia Cao, Zhimei Tian, Binsheng Yang & Pin Yang
Pages: 1065-1082
Published online: 21 Feb 2014
AbstractforIn vivo enhancement of anticancer therapy using bare or chemotherapeutic drug-bearing nanodiamond particles | Full Text | References | PDF (6.2 MB)
  • 58 Views
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Article
Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells
Lei Li, Dongxi Xiang, Sarah Shigdar, Wenrong Yang, Qiong Li, Jia Lin, Kexin Liu & Wei Duan
Pages: 1083-1096
Published online: 21 Feb 2014
AbstractforEpithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells | Full Text | References | PDF (1.5 MB)
  • 266 Views
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Article
A reusable localized surface plasmon resonance biosensor for quantitative detection of serum squamous cell carcinoma antigen in cervical cancer patients based on silver nanoparticles array
Qianying Zhao, Ruiqi Duan, Jialing Yuan, Yi Quan, Huan Yang & Mingrong Xi
Pages: 1097-1104
Published online: 22 Feb 2014
AbstractforA reusable localized surface plasmon resonance biosensor for quantitative detection of serum squamous cell carcinoma antigen in cervical cancer patients based on silver nanoparticles array | Full Text | References | PDF (800.7 KB)
  • 150 Views
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Letter

Letter
Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles
Denis Girard
Pages: 1105-1109
Published online: 24 Feb 2014
First Page PreviewforUsing the air pouch model for assessing in vivo inflammatory activity of nanoparticles | Full Text | References | PDF (183.2 KB)
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Research Article

Article
Direct electrochemical oxidation of S-captopril using gold electrodes modified with graphene-AuAg nanocomposites
Florina Pogacean, Alexandru R Biris, Maria Coros, Mihaela Diana Lazar, Fumiya Watanabe, Ganesh K Kannarpady, Said A Farha Al Said, Alexandru S Biris & Stela Pruneanu
Pages: 1111-1125
Published online: 25 Feb 2014
AbstractforDirect electrochemical oxidation of S-captopril using gold electrodes modified with graphene-AuAg nanocomposites | Full Text | References | PDF (3.7 MB)
  • 52 Views
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Article
RETRACTED ARTICLE: Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite
Li-Xia Hu, Hong Wang, Meng Rao, Xiao-Ling Zhao, Jing Yang, Shi-Fu Hu, Jing He, Wei Xia, Hefang Liu, Bo Zhen, Haihong Di, Changsheng Xie, Xianping Xia & Changhong Zhu
Pages: 1127-1138
Published online: 25 Feb 2014
AbstractforRETRACTED ARTICLE: Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite | PDF (7.2 MB)
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Original Research

Article
Chemotherapeutic potential of curcumin-bearing microcells against hepatocellular carcinoma in model animals
Mohammad Farazuddin, Bhavyata Dua, Qamar Zia, Aijaz Ahmad Khan, Beenu Joshi & Mohammad Owais
Pages: 1139-1152
Published online: 03 Mar 2014
AbstractforChemotherapeutic potential of curcumin-bearing microcells against hepatocellular carcinoma in model animals | Full Text | References | PDF (1.9 MB)
  • 63 Views
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Article
Intracellular delivery of cell-penetrating peptide-transcriptional factor fusion protein and its role in selective osteogenesis
Jin Sook Suh, Jue Yeon Lee, Yoon Jung Choi, Hyung Keun You, Seong-Doo Hong, Chong Pyoung Chung & Yoon Jeong Park
Pages: 1153-1166
Published online: 10 Mar 2014
AbstractforIntracellular delivery of cell-penetrating peptide-transcriptional factor fusion protein and its role in selective osteogenesis | Full Text | References | PDF (3 MB)
  • 65 Views
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Research Article

Article
Facile method for the synthesis of silver nanoparticles using 3-hydrazino-isatin derivatives in aqueous methanol and their antibacterial activity
Ayman El-Faham, Ahmed A Elzatahry, Zeid A Al-Othman & Elsayed Ahmed Elsayed
Pages: 1167-1174
Published online: 05 Mar 2014
AbstractforFacile method for the synthesis of silver nanoparticles using 3-hydrazino-isatin derivatives in aqueous methanol and their antibacterial activity | Full Text | References | PDF (2 MB)
  • 133 Views
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Article
Biological activity of lactoferrin-functionalized biomimetic hydroxyapatite nanocrystals
Nunzia Nocerino, Andrea Fulgione, Marco Iannaccone, Laura Tomasetta, Flora Ianniello, Francesca Martora, Marco Lelli, Norberto Roveri, Federico Capuano & Rosanna Capparelli
Pages: 1175-1184
Published online: 05 Mar 2014
AbstractforBiological activity of lactoferrin-functionalized biomimetic hydroxyapatite nanocrystals | Full Text | References | PDF (1.3 MB)
  • 74 Views
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Article
Effects of titania nanotubes with or without bovine serum albumin loaded on human gingival fibroblasts
Xiangning Liu, Xiaosong Zhou, Shaobing Li, Renfa Lai, Zhiying Zhou, Ye Zhang & Lei Zhou
Pages: 1185-1198
Published online: 06 Mar 2014
AbstractforEffects of titania nanotubes with or without bovine serum albumin loaded on human gingival fibroblasts | Full Text | References | PDF (2.5 MB)
  • 61 Views
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Original Research

Article
Aluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy
Luis Alexandre Muehlmann, Beatriz Chiyin Ma, João Paulo Figueiró Longo, Maria de Fátima Menezes Almeida Santos & Ricardo Bentes Azevedo
Pages: 1199-1213
Published online: 07 Mar 2014
AbstractforAluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy | Full Text | References | PDF (1.7 MB)
  • 129 Views
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Article
Inhibited bacterial biofilm formation and improved osteogenic activity on gentamicin-loaded titania nanotubes with various diameters
Wen-tao Lin, Hong-lue Tan, Zhao-ling Duan, Bing Yue, Rui Ma, Guo He & Ting-ting Tang
Pages: 1215-1230
Published online: 07 Mar 2014
AbstractforInhibited bacterial biofilm formation and improved osteogenic activity on gentamicin-loaded titania nanotubes with various diameters | Full Text | References | PDF (9.1 MB)
  • 84 Views
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Article
Lipid nanoparticles for topical and transdermal application for alopecia treatment: development, physicochemical characterization, and in vitro release and penetration studies
Maria João Gomes, Susana Martins, Domingos Ferreira, Marcela A Segundo & Salette Reis
Pages: 1231-1242
Published online: 07 Mar 2014
AbstractforLipid nanoparticles for topical and transdermal application for alopecia treatment: development, physicochemical characterization, and in vitro release and penetration studies | Full Text | References | PDF (587.8 KB)
  • 408 Views
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Article
Direct role of interrod spacing in mediating cell adhesion on Sr-HA nanorod-patterned coatings
Jianhong Zhou, Yong Han & Shemin Lu
Pages: 1243-1260
Published online: 08 Mar 2014
AbstractforDirect role of interrod spacing in mediating cell adhesion on Sr-HA nanorod-patterned coatings | Full Text | References | PDF (4.2 MB)
  • 62 Views
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Article
Potential proinflammatory effects of hydroxyapatite nanoparticles on endothelial cells in a monocyte–endothelial cell coculture model
Xin Liu & Jiao Sun
Pages: 1261-1273
Published online: 11 Mar 2014
AbstractforPotential proinflammatory effects of hydroxyapatite nanoparticles on endothelial cells in a monocyte–endothelial cell coculture model | Full Text | References | PDF (3.1 MB)
  • 58 Views
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Article
Carbon nanotubes as VEGF carriers to improve the early vascularization of porcine small intestinal submucosa in abdominal wall defect repair
Zhengni Liu, Xueyi Feng, Huichun Wang, Jun Ma, Wei Liu, Daxiang Cui, Yan Gu & Rui Tang
Pages: 1275-1286
Published online: 10 Mar 2014
AbstractforCarbon nanotubes as VEGF carriers to improve the early vascularization of porcine small intestinal submucosa in abdominal wall defect repair | Full Text | References | PDF (3.2 MB)
  • 63 Views
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Article
Colloidal graphite/graphene nanostructures using collagen showing enhanced thermal conductivity
Soumya Bhattacharya, Purbarun Dhar, Sarit K Das, Ranjan Ganguly, Thomas J Webster & Suprabha Nayar
Pages: 1287-1298
Published online: 10 Mar 2014
AbstractforColloidal graphite/graphene nanostructures using collagen showing enhanced thermal conductivity | Full Text | References | PDF (3.8 MB)
  • 74 Views
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Article
The development, fabrication, and material characterization of polypropylene composites reinforced with carbon nanofiber and hydroxyapatite nanorod hybrid fillers
Cheng Zhu Liao, Hoi Man Wong, Kelvin Wai Kwok Yeung & Sie Chin Tjong
Pages: 1299-1310
Published online: 11 Mar 2014
AbstractforThe development, fabrication, and material characterization of polypropylene composites reinforced with carbon nanofiber and hydroxyapatite nanorod hybrid fillers | Full Text | References | PDF (4.8 MB)
  • 72 Views
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Article
Coupling of a bifunctional peptide R13 to OTMCS-PEI copolymer as a gene vector increases transfection efficiency and tumor targeting
Hui Lv, Qing Zhu, Kewu Liu, Manman Zhu, Wenfang Zhao, Yuan Mao & Kehai Liu
Pages: 1311-1322
Published online: 11 Mar 2014
AbstractforCoupling of a bifunctional peptide R13 to OTMCS-PEI copolymer as a gene vector increases transfection efficiency and tumor targeting | Full Text | References | PDF (2.6 MB)
  • 40 Views
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Article
Near-infrared quantum dots for HER2 localization and imaging of cancer cells
Sarwat B Rizvi, Sepideh Rouhi, Shohei Taniguchi, Shi Yu Yang, Mark Green, Mo Keshtgar & Alexander M Seifalian
Pages: 1323-1337
Published online: 11 Mar 2014
AbstractforNear-infrared quantum dots for HER2 localization and imaging of cancer cells | Full Text | References | PDF (5 MB)
  • 99 Views
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Article
Quantum dot-based immunofluorescent imaging of Ki67 and identification of prognostic value in HER2-positive (non-luminal) breast cancer
Jin-Zhong Sun, Chuang Chen, Guan Jiang, Wei-Qun Tian, Yan Li & Sheng-Rong Sun
Pages: 1339-1346
Published online: 11 Mar 2014
AbstractforQuantum dot-based immunofluorescent imaging of Ki67 and identification of prognostic value in HER2-positive (non-luminal) breast cancer | Full Text | References | PDF (2 MB)
  • 102 Views
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Review

Review Article
Near-infrared fluorescent probes in cancer imaging and therapy: an emerging field
Xiaomin Yi, Fuli Wang, Weijun Qin, Xiaojian Yang & Jianlin Yuan
Pages: 1347-1365
Published online: 05 Mar 2014
AbstractforNear-infrared fluorescent probes in cancer imaging and therapy: an emerging field | Full Text | References | PDF (2 MB)
  • 355 Views
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Original Research

Article
Cryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes
Christopher B Fox, Sean K Mulligan, Joyce Sung, Quinton M Dowling, H W Millie Fung, Thomas S Vedvick & Rhea N Coler
Pages: 1367-1377
Published online: 11 Mar 2014
AbstractforCryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes | Full Text | References | PDF (3.1 MB)
  • 87 Views
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Article
Cytotoxicity and genotoxicity caused by yttrium oxide nanoparticles in HEK293 cells
Vellaisamy Selvaraj, Sravanthi Bodapati, Elizabeth Murray, Kevin M Rice, Nicole Winston, Tolou Shokuhfar, Yu Zhao & Eric Blough
Pages: 1379-1391
Published online: 12 Mar 2014
AbstractforCytotoxicity and genotoxicity caused by yttrium oxide nanoparticles in HEK293 cells | Full Text | References | PDF (3.4 MB)
  • 225 Views
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Article
Acute toxicity of nickel nanoparticles in rats after intravenous injection
Ruth R Magaye, Xia Yue, Baobo Zou, Hongbo Shi, Hongsheng Yu, Kui Liu, Xialu Lin, Jin Xu, Cui Yang, Aiguo Wu & Jinshun Zhao
Pages: 1393-1402
Published online: 12 Mar 2014
AbstractforAcute toxicity of nickel nanoparticles in rats after intravenous injection | Full Text | References | PDF (4 MB)
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Article
Detection of haplotype mutations of the MD-2 gene promoter associated with Der p2-induced allergy using a nanostructured biosensor
Yu-Ting Chin, En-Chih Liao, Chia-Che Wu, Gou-Jen Wang & Jaw-Ji Tsai
Pages: 1403-1412
Published online: 12 Mar 2014
AbstractforDetection of haplotype mutations of the MD-2 gene promoter associated with Der p2-induced allergy using a nanostructured biosensor | Full Text | References | PDF (1.7 MB)
  • 45 Views
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Article
Cytotoxicity of graphene oxide and graphene oxide loaded with doxorubicin on human multiple myeloma cells
Shaoling Wu, Xindong Zhao, Zhongguang Cui, Chunting Zhao, Yuzhen Wang, Li Du & Yanhui Li
Pages: 1413-1421
Published online: 14 Mar 2014
AbstractforCytotoxicity of graphene oxide and graphene oxide loaded with doxorubicin on human multiple myeloma cells | Full Text | References | PDF (1.4 MB)
  • 111 Views
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Article
Bone plate composed of a ternary nano-hydroxyapatite/polyamide 66/glass fiber composite: biomechanical properties and biocompatibility
Bo Qiao, Jidong Li, Qingmao Zhu, Shuquan Guo, Xiaotong Qi, Weichao Li, Jun Wu, Yang Liu & Dianming Jiang
Pages: 1423-1432
Published online: 17 Mar 2014
AbstractforBone plate composed of a ternary nano-hydroxyapatite/polyamide 66/glass fiber composite: biomechanical properties and biocompatibility | Full Text | References | PDF (5.1 MB)
  • 80 Views
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Article
Chlorotoxin-conjugated graphene oxide for targeted delivery of an anticancer drug
Hao Wang, Wei Gu, Ning Xiao, Ling Ye & Qunyuan Xu
Pages: 1433-1442
Published online: 18 Mar 2014
AbstractforChlorotoxin-conjugated graphene oxide for targeted delivery of an anticancer drug | Full Text | References | PDF (2.7 MB)
  • 97 Views
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Article
Cisplatin improves antitumor activity of weekly nab-paclitaxel in patients with metastatic breast cancer
Si Sun, Lichen Tang, Jian Zhang, Fangfang Lv, Zhonghua Wang, Leiping Wang, Qunling Zhang, Chunlei Zheng, Lixin Qiu, Zhen Jia, Yunhua Lu, Guangyu Liu, Zhimin Shao, Biyun Wang & Xichun Hu
Pages: 1443-1452
Published online: 19 Mar 2014
AbstractforCisplatin improves antitumor activity of weekly nab-paclitaxel in patients with metastatic breast cancer | Full Text | References | PDF (368.6 KB)
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Article
Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus
Lucian Mocan, Ioana Ilie, Cristian Matea, Flaviu Tabaran, Ersjebet Kalman, Cornel Iancu & Teodora Mocan
Pages: 1453-1461
Published online: 22 Mar 2014
AbstractforSurface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus | Full Text | References | PDF (1.6 MB)
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Article
Synthesis of ciprofloxacin-conjugated poly (L-lactic acid) polymer for nanofiber fabrication and antibacterial evaluation
Sharad P Parwe, Priti N Chaudhari, Kavita K Mohite, Balaji S Selukar, Smita S Nande & Baijayantimala Garnaik
Pages: 1463-1477
Published online: 26 Mar 2014
AbstractforSynthesis of ciprofloxacin-conjugated poly (L-lactic acid) polymer for nanofiber fabrication and antibacterial evaluation | Full Text | References | PDF (4.4 MB)
  • 180 Views
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Article
Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide
Khaled Messaoudi, Patrick Saulnier, Kim Boesen, Jean-Pierre Benoit & Frederic Lagarce
Pages: 1479-1490
Published online: 24 Mar 2014
AbstractforAnti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide | Full Text | References | PDF (442.5 KB)
  • 79 Views
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Article
MR imaging and targeting of a specific alveolar macrophage subpopulation in LPS-induced COPD animal model using antibody-conjugated magnetic nanoparticles
Achraf Al Faraj, Asma Sultana Shaik, Sibtain Afzal, Baraa Al Sayed & Rabih Halwani
Pages: 1491-1503
Published online: 24 Mar 2014
AbstractforMR imaging and targeting of a specific alveolar macrophage subpopulation in LPS-induced COPD animal model using antibody-conjugated magnetic nanoparticles | Full Text | References | PDF (1.8 MB)
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Article
Effects of intraperitoneally injected silver nanoparticles on histological structures and blood parameters in the albino rat
Osama Mohamed M Sarhan & Rehab M Hussein
Pages: 1505-1517
Published online: 24 Mar 2014
AbstractforEffects of intraperitoneally injected silver nanoparticles on histological structures and blood parameters in the albino rat | Full Text | References | PDF (9.1 MB)
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Article
An innovative approach to induce cross-protective immunity against porcine reproductive and respiratory syndrome virus in the lungs of pigs through adjuvanted nanotechnology-based vaccination
Basavaraj Binjawadagi, Varun Dwivedi, Cordelia Manickam, Kang Ouyang, Jordi B Torrelles & Gourapura J Renukaradhya
Pages: 1519-1535
Published online: 24 Mar 2014
AbstractforAn innovative approach to induce cross-protective immunity against porcine reproductive and respiratory syndrome virus in the lungs of pigs through adjuvanted nanotechnology-based vaccination | Full Text | References | PDF (2.4 MB)
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Review

Review Article
Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs
Antonella Accardo, Luigi Aloj, Michela Aurilio, Giancarlo Morelli & Diego Tesauro
Pages: 1537-1557
Published online: 27 Mar 2014
AbstractforReceptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs | Full Text | References | PDF (2.4 MB)
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Original Research

Article
Effects of magnetic cobalt ferrite nanoparticles on biological and artificial lipid membranes
Barbara Drašler, Damjana Drobne, Sara Novak, Janez Valant, Sabina Boljte, Lado Otrin, Michael Rappolt, Barbara Sartori, Aleš Iglič, Veronika Kralj-Iglič, Vid Šuštar, Darko Makovec, Sašo Gyergyek, Matej Hočevar, Matjaž Godec & Jernej Zupanc
Pages: 1559-1581
Published online: 27 Mar 2014
AbstractforEffects of magnetic cobalt ferrite nanoparticles on biological and artificial lipid membranes | Full Text | References | PDF (6 MB)
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Article
Methotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased antineoplastic effects in resistant breast cancer cell line
Virginia C Yurgel, Catiuscia P Oliveira, Karine R Begnini, Eduarda Schultze, Helena S Thurow, Priscila MM Leon, Odir A Dellagostin, Vinicius F Campos, Ruy CR Beck, Silvia S Guterres, Tiago Collares, Adriana R Pohlmann & Fabiana K Seixas
Pages: 1583-1591
Published online: 25 Mar 2014
AbstractforMethotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased antineoplastic effects in resistant breast cancer cell line | Full Text | References | PDF (780.2 KB)
  • 79 Views
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Article
Biosynthesis and characterization of silver nanoparticles using panchakavya, an Indian traditional farming formulating agent
Muthusamy Govarthanan, Thangasamy Selvankumar, Koildhasan Manoharan, Rajiniganth Rathika, Kuppusamy Shanthi, Kui-Jae Lee, Min Cho, Seralathan Kamala-Kannan & Byung-Taek Oh
Pages: 1593-1599
Published online: 31 Mar 2014
AbstractforBiosynthesis and characterization of silver nanoparticles using panchakavya, an Indian traditional farming formulating agent | Full Text | References | PDF (597.2 KB)
  • 157 Views
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Article
Surface engineered antifouling optomagnetic SPIONs for bimodal targeted imaging of pancreatic cancer cells
Xiaohui Wang, Xiaohong Xing, Bingbo Zhang, Fengjun Liu, Yingsheng Cheng & Donglu Shi
Pages: 1601-1615
Published online: 27 Mar 2014
AbstractforSurface engineered antifouling optomagnetic SPIONs for bimodal targeted imaging of pancreatic cancer cells | Full Text | References | PDF (3.3 MB)
  • 92 Views
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Review

Review Article
Genetically engineered nanocarriers for drug delivery
Pu Shi, Joshua A Gustafson & J Andrew MacKay
Pages: 1617-1626
Published online: 26 Mar 2014
AbstractforGenetically engineered nanocarriers for drug delivery | Full Text | References | PDF (2 MB)
  • 153 Views
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Editorial

Editorial
Targeted nanotherapeutics in cancer
Farooq A Shiekh
Pages: 1627-1628
Published online: 26 Mar 2014
CitationforTargeted nanotherapeutics in cancer | Full Text | References | PDF (118 KB)
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Original Research

Article
Heat-transfer-based detection of SNPs in the PAH gene of PKU patients
Natalie Vanden Bon, Bart van Grinsven, Mohammed Sharif Murib, Weng Siang Yeap, Ken Haenen, Ward De Ceuninck, Patrick Wagner, Marcel Ameloot, Veronique Vermeeren & Luc Michiels
Pages: 1629-1640
Published online: 27 Mar 2014
AbstractforHeat-transfer-based detection of SNPs in the PAH gene of PKU patients | Full Text | References | PDF (1.2 MB)
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Review

Review Article
Stem cell tracking using iron oxide nanoparticles
Elizabeth Bull, Seyed Yazdan Madani, Roosey Sheth, Amelia Seifalian, Mark Green & Alexander M Seifalian
Pages: 1641-1653
Published online: 31 Mar 2014
AbstractforStem cell tracking using iron oxide nanoparticles | Full Text | References | PDF (1.6 MB)
  • 251 Views
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Original Research

Article
Adenosine diphosphate-decorated chitosan nanoparticles shorten blood clotting times, influencing the structures and varying the mechanical properties of the clots
Tze-Wen Chung, Pei-Yi Lin, Shoei-Shen Wang & Yen-Fung Chen
Pages: 1655-1664
Published online: 31 Mar 2014
AbstractforAdenosine diphosphate-decorated chitosan nanoparticles shorten blood clotting times, influencing the structures and varying the mechanical properties of the clots | Full Text | References | PDF (2.5 MB)
  • 71 Views
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Article
Preparation of redispersible liposomal dry powder using an ultrasonic spray freeze-drying technique for transdermal delivery of human epithelial growth factor
Fei Yin, Shiyan Guo, Yong Gan & Xinxin Zhang
Pages: 1665-1676
Published online: 31 Mar 2014
AbstractforPreparation of redispersible liposomal dry powder using an ultrasonic spray freeze-drying technique for transdermal delivery of human epithelial growth factor | Full Text | References | PDF (3.6 MB)
  • 85 Views
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Article
Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride
Iwona Inkielewicz-Stepniak, Maria Jose Santos-Martinez, Carlos Medina & Marek W Radomski
Pages: 1677-1687
Published online: 02 Apr 2014
AbstractforPharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride | Full Text | References | PDF (2.6 MB)
  • 118 Views
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Article
Fracture toughness of titanium–cement interfaces: effects of fibers and loading angles
Morshed Khandaker, Khatri Chhetri Utsaha & Tracy Morris
Pages: 1689-1697
Published online: 01 Apr 2014
AbstractforFracture toughness of titanium–cement interfaces: effects of fibers and loading angles | Full Text | References | PDF (1.9 MB)
  • 49 Views
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Article
Lateral flow test strip based on colloidal selenium immunoassay for rapid detection of melamine in milk, milk powder, and animal feed
Zhizeng Wang, Dejuan Zhi, Yang Zhao, Hailong Zhang, Xin Wang, Yi Ru & Hongyu Li
Pages: 1699-1707
Published online: 03 Apr 2014
AbstractforLateral flow test strip based on colloidal selenium immunoassay for rapid detection of melamine in milk, milk powder, and animal feed | Full Text | References | PDF (3.5 MB)
  • 103 Views
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Article
Preparation and in vitro/in vivo characterization of enteric-coated nanoparticles loaded with the antihypertensive peptide VLPVPR
Haiyan Sun, Dong Liu, Yan Li, Xuwei Tang & Yanli Cong
Pages: 1709-1716
Published online: 03 Apr 2014
AbstractforPreparation and in vitro/in vivo characterization of enteric-coated nanoparticles loaded with the antihypertensive peptide VLPVPR | Full Text | References | PDF (1.2 MB)
  • 78 Views
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Article
Synthesis, characterization, and evaluation of antibacterial effect of Ag nanoparticles against Escherichia coli O157:H7 and methicillin-resistant Staphylococcus aureus (MRSA)
Daissy Paredes, Claudia Ortiz & Rodrigo Torres
Pages: 1717-1729
Published online: 03 Apr 2014
AbstractforSynthesis, characterization, and evaluation of antibacterial effect of Ag nanoparticles against Escherichia coli O157:H7 and methicillin-resistant Staphylococcus aureus (MRSA) | Full Text | References | PDF (2.8 MB)
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Article
In vivo MR detection of fluorine-labeled human MSC using the bSSFP sequence
Emeline J Ribot, Jeffrey M Gaudet, Yuhua Chen, Kyle M Gilbert & Paula J Foster
Pages: 1731-1739
Published online: 08 Apr 2014
AbstractforIn vivo MR detection of fluorine-labeled human MSC using the bSSFP sequence | Full Text | References | PDF (1.8 MB)
  • 68 Views
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Article
RETRACTED ARTICLE: Osteogenic activity of titanium surfaces with nanonetwork structures
Helin Xing, Satoshi Komasa, Yoichiro Taguchi, Tohru Sekino & Joji Okazaki
Pages: 1741-1755
Published online: 05 Apr 2014
AbstractforRETRACTED ARTICLE: Osteogenic activity of titanium surfaces with nanonetwork structures | PDF (4.2 MB)
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Review

Review Article
Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system
Maria João Gomes, José das Neves & Bruno Sarmento
Pages: 1757-1769
Published online: 07 Apr 2014
AbstractforNanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system | Full Text | References | PDF (1.4 MB)
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Letter

Letter
Multifunctional nanosystems: growing sanguinity in siRNA therapy
Khan Farheen Badrealam & Mohammad Owais
Pages: 1771-1773
Published online: 10 Apr 2014
First Page PreviewforMultifunctional nanosystems: growing sanguinity in siRNA therapy | Full Text | References | PDF (125 KB)
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Original Research

Article
Decreased Staphylococcus aureus and increased osteoblast density on nanostructured electrophoretic-deposited hydroxyapatite on titanium without the use of pharmaceuticals
Dennis Mathew, Garima Bhardwaj, Qi Wang, Linlin Sun, Batur Ercan, Manisavagam Geetha & Thomas J Webster
Pages: 1775-1781
Published online: 08 Apr 2014
AbstractforDecreased Staphylococcus aureus and increased osteoblast density on nanostructured electrophoretic-deposited hydroxyapatite on titanium without the use of pharmaceuticals | Full Text | References | PDF (3 MB)
  • 58 Views
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Article
An in vitro evaluation of graphene oxide reduced by Ganoderma spp. in human breast cancer cells (MDA-MB-231)
Sangiliyandi Gurunathan, JaeWoong Han, Jung Hyun Park & Jin Hoi Kim
Pages: 1783-1797
Published online: 08 Apr 2014
AbstractforAn in vitro evaluation of graphene oxide reduced by Ganoderma spp. in human breast cancer cells (MDA-MB-231) | Full Text | References | PDF (1.7 MB)
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Article
A nanotechnological, molecular-modeling, and immunological approach to study the interaction of the anti-tumorigenic peptide p28 with the p53 family of proteins
Emilia Coppari, Tohru Yamada, Anna Rita Bizzarri, Craig W Beattie & Salvatore Cannistraro
Pages: 1799-1813
Published online: 10 Apr 2014
AbstractforA nanotechnological, molecular-modeling, and immunological approach to study the interaction of the anti-tumorigenic peptide p28 with the p53 family of proteins | Full Text | References | PDF (2.6 MB)
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Article
R2* and R2 mapping for quantifying recruitment of superparamagnetic iron oxide-tagged endothelial progenitor cells to injured liver: tracking in vitro and in vivo
Qingguo Wang, Kangan Li, Qimeng Quan & Guixiang Zhang
Pages: 1815-1822
Published online: 11 Apr 2014
AbstractforR2* and R2 mapping for quantifying recruitment of superparamagnetic iron oxide-tagged endothelial progenitor cells to injured liver: tracking in vitro and in vivo | Full Text | References | PDF (2 MB)
  • 54 Views
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Article
Development of a liposome-based formulation for vitamin K1 nebulization on the skin
Virginia Campani, Dario Marchese, Maria Teresa Pitaro, Michele Pitaro, Paolo Grieco & Giuseppe De Rosa
Pages: 1823-1832
Published online: 10 Apr 2014
AbstractforDevelopment of a liposome-based formulation for vitamin K1 nebulization on the skin | Full Text | References | PDF (835.4 KB)
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Review

Review Article
Development of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles
Alicia Rodríguez-Gascón, Ana del Pozo-Rodríguez & María Ángeles Solinís
Pages: 1833-1843
Published online: 10 Apr 2014
AbstractforDevelopment of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles | Full Text | References | PDF (553.5 KB)
  • 296 Views
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Original Research

Article
Novel nano-rough polymers for cartilage tissue engineering
Ganesan Balasundaram, Daniel M Storey & Thomas J Webster
Pages: 1845-1853
Published online: 15 Apr 2014
AbstractforNovel nano-rough polymers for cartilage tissue engineering | Full Text | References | PDF (1.4 MB)
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Article
Shikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian cancer
Efthymia-Iliana Matthaiou, Jaleh Barar, Raphael Sandaltzopoulos, Chunsheng Li, George Coukos & Yadollah Omidi
Pages: 1855-1870
Published online: 15 Apr 2014
AbstractforShikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian cancer | Full Text | References | PDF (3.7 MB)
  • 121 Views
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Article
Synthesis and in vitro antineoplastic evaluation of silver nanoparticles mediated by Agrimoniae herba extract
Ding Qu, Wenjie Sun, Yan Chen, Jing Zhou & Congyan Liu
Pages: 1871-1882
Published online: 15 Apr 2014
AbstractforSynthesis and in vitro antineoplastic evaluation of silver nanoparticles mediated by Agrimoniae herba extract | Full Text | References | PDF (1.7 MB)
  • 111 Views
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Article
Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles
Galina F Prozorova, Alexsandr S Pozdnyakov, Nadezhda P Kuznetsova, Svetlana A Korzhova, Artem I Emel’yanov, Tamara G Ermakova, Tat’yana V Fadeeva & Larisa M Sosedova
Pages: 1883-1889
Published online: 16 Apr 2014
AbstractforGreen synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles | Full Text | References | PDF (1.6 MB)
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Article
Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation
Sandeep S Hedgire, Mari Mino-Kenudson, Azadeh Elmi, Sarah Thayer, Carlos Fernandez-del Castillo & Mukesh G Harisinghani
Pages: 1891-1896
Published online: 17 Apr 2014
AbstractforEnhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation | Full Text | References | PDF (827.6 KB)
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Article
Sequential release of salidroside and paeonol from a nanosphere-hydrogel system inhibits ultraviolet B-induced melanogenesis in guinea pig skin
Li-Hua Peng, Shen-Yao Xu, Ying-Hui Shan, Wei Wei, Shuai Liu, Chen-Zhen Zhang, Jia-He Wu, Wen-Quan Liang & Jian-Qing Gao
Pages: 1897-1908
Published online: 16 Apr 2014
AbstractforSequential release of salidroside and paeonol from a nanosphere-hydrogel system inhibits ultraviolet B-induced melanogenesis in guinea pig skin | Full Text | References | PDF (2.2 MB)
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Article
Preparation and properties of poly(vinyl alcohol)/chitosan blend bionanocomposites reinforced with cellulose nanocrystals/ZnO-Ag multifunctional nanosized filler
Susan Azizi, Mansor Bin Ahmad, Mohd Zobir Hussein, Nor Azowa Ibrahim & Farideh Namvar
Pages: 1909-1917
Published online: 23 Apr 2014
AbstractforPreparation and properties of poly(vinyl alcohol)/chitosan blend bionanocomposites reinforced with cellulose nanocrystals/ZnO-Ag multifunctional nanosized filler | Full Text | References | PDF (2.2 MB)
  • 232 Views
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Article
Biodistribution and acute toxicity of a nanofluid containing manganese iron oxide nanoparticles produced by a mechanochemical process
Mariangela Bellusci, Aurelio La Barbera, Franco Padella, Mariateresa Mancuso, Alessandra Pasquo, Maria Giuseppa Grollino, Giorgio Leter, Elisa Nardi, Carlo Cremisini, Paola Giardullo & Francesca Pacchierotti
Pages: 1919-1929
Published online: 17 Apr 2014
AbstractforBiodistribution and acute toxicity of a nanofluid containing manganese iron oxide nanoparticles produced by a mechanochemical process | Full Text | References | PDF (2.6 MB)
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Article
Photothermolysis mediated by gold nanorods modified with EGFR monoclonal antibody induces Hep-2 cells apoptosis in vitro and in vivo
Shiwen Zhang, Yunlong Li, Xiaoguang He, Shouan Dong, Yunchao Huang, Xiaojiang Li, Yuxiao Li, Congguo Jin, Yingying Zhang & Yuanling Wang
Pages: 1931-1946
Published online: 17 Apr 2014
AbstractforPhotothermolysis mediated by gold nanorods modified with EGFR monoclonal antibody induces Hep-2 cells apoptosis in vitro and in vivo | Full Text | References | PDF (4.9 MB)
  • 55 Views
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Article
Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish
Joseph B Pryor, Bryan J Harper & Stacey L Harper
Pages: 1947-1956
Published online: 17 Apr 2014
AbstractforComparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish | Full Text | References | PDF (495.9 KB)
  • 93 Views
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Article
Preparation and properties of BSA-loaded microspheres based on multi-(amino acid) copolymer for protein delivery
Xingtao Chen, Guoyu Lv, Jue Zhang, Songchao Tang, Yonggang Yan, Zhaoying Wu, Jiacan Su & Jie Wei
Pages: 1957-1965
Published online: 07 May 2014
AbstractforPreparation and properties of BSA-loaded microspheres based on multi-(amino acid) copolymer for protein delivery | Full Text | References | PDF (2.1 MB)
  • 56 Views
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Article
Electrosprayed core–shell solid dispersions of acyclovir fabricated using an epoxy-coated concentric spray head
Zhe-Peng Liu, Lei Cui, Deng-Guang Yu, Zhuan-Xia Zhao & Lan Chen
Pages: 1967-1977
Published online: 16 Apr 2014
AbstractforElectrosprayed core–shell solid dispersions of acyclovir fabricated using an epoxy-coated concentric spray head | Full Text | References | PDF (2.6 MB)
  • 73 Views
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Article
Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells
Hisao Haniu, Naoto Saito, Yoshikazu Matsuda, Tamotsu Tsukahara, Yuki Usui, Kayo Maruyama, Seiji Takanashi, Kaoru Aoki, Shinsuke Kobayashi, Hiroki Nomura, Manabu Tanaka, Masanori Okamoto & Hiroyuki Kato
Pages: 1979-1990
Published online: 17 Apr 2014
AbstractforBiological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells | Full Text | References | PDF (4 MB)
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Article
Preparation and characterization of polylactide/poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) hybrid fibers for potential application in bone tissue engineering
YueLong Wang, Gang Guo, HaiFeng Chen, Xiang Gao, RangRang Fan, DongMei Zhang & LiangXue Zhou
Pages: 1991-2003
Published online: 17 Apr 2014
AbstractforPreparation and characterization of polylactide/poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) hybrid fibers for potential application in bone tissue engineering | Full Text | References | PDF (2.6 MB)
  • 76 Views
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Article
Role of the charge, carbon chain length, and content of surfactant on the skin penetration of meloxicam-loaded liposomes
Sureewan Duangjit, Boonnada Pamornpathomkul, Praneet Opanasopit, Theerasak Rojanarata, Yasuko Obata, Kozo Takayama & Tanasait Ngawhirunpat
Pages: 2005-2017
Published online: 29 Apr 2014
AbstractforRole of the charge, carbon chain length, and content of surfactant on the skin penetration of meloxicam-loaded liposomes | Full Text | References | PDF (2 MB)
  • 178 Views
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Article
Folate-targeted paclitaxel-conjugated polymeric micelles inhibits pulmonary metastatic hepatoma in experimental murine H22 metastasis models
Yan Zhang, Hui Zhang, Wenbin Wu, Fuhong Zhang, Shi Liu, Rui Wang, Yingchun Sun, Ti Tong & Xiabin Jing
Pages: 2019-2030
Published online: 23 Apr 2014
AbstractforFolate-targeted paclitaxel-conjugated polymeric micelles inhibits pulmonary metastatic hepatoma in experimental murine H22 metastasis models | Full Text | References | PDF (2.4 MB)
  • 67 Views
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Article
Tissue-specific direct microtransfer of nanomaterials into Drosophila embryos as a versatile in vivo test bed for nanomaterial toxicity assessment
Sasha Vega-Alvarez, Adriana Herrera, Carlos Rinaldi & Franklin A Carrero-Martínez
Pages: 2031-2041
Published online: 22 Apr 2014
AbstractforTissue-specific direct microtransfer of nanomaterials into Drosophila embryos as a versatile in vivo test bed for nanomaterial toxicity assessment | Full Text | References | PDF (1.1 MB)
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Article
Apoptosis selectively induced in BEL-7402 cells by folic acid-modified magnetic nanoparticles combined with 100 Hz magnetic field
Jian Wen, Shulian Jiang, Zhiqiang Chen, Wei Zhao, Yongxiang Yi, Ruili Yang & Baoan Chen
Pages: 2043-2050
Published online: 23 Apr 2014
AbstractforApoptosis selectively induced in BEL-7402 cells by folic acid-modified magnetic nanoparticles combined with 100 Hz magnetic field | Full Text | References | PDF (700.7 KB)
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Review

Review Article
Nanomedicines in the treatment of hepatitis C virus infection in Asian patients: optimizing use of peginterferon alfa
Chen-Hua Liu & Jia-Horng Kao
Pages: 2051-2067
Published online: 25 Apr 2014
AbstractforNanomedicines in the treatment of hepatitis C virus infection in Asian patients: optimizing use of peginterferon alfa | Full Text | References | PDF (450.4 KB)
  • 53 Views
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Letter

Letter
Passing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications
Xiao-Dong Zhang, Jiang Yang, Sha-Sha Song, Wei Long, Jie Chen, Xiu Shen, Hao Wang, Yuan-Ming Sun, Pei-Xun Liu & Saijun Fan
Pages: 2069-2072
Published online: 25 Apr 2014
AbstractforPassing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications | Full Text | References | PDF (410.6 KB)
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Original Research

Article
Polyhydroxylated fullerene attenuates oxidative stress-induced apoptosis via a fortifying Nrf2-regulated cellular antioxidant defence system
Shefang Ye, Min Chen, Yuanqin Jiang, Mingliang Chen, Tong Zhou, Yange Wang, Zhenqing Hou & Lei Ren
Pages: 2073-2087
Published online: 29 Apr 2014
AbstractforPolyhydroxylated fullerene attenuates oxidative stress-induced apoptosis via a fortifying Nrf2-regulated cellular antioxidant defence system | Full Text | References | PDF (3.4 MB)
  • 72 Views
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Article
Novel designed polyoxyethylene nonionic surfactant with improved safety and efficiency for anticancer drug delivery
Chang Li, Chunmeng Sun, Shasha Li, Peng Han, Huimin Sun, Ammar Ouahab, Yan Shen, Yourui Xu, Yerong Xiong & Jiasheng Tu
Pages: 2089-2100
Published online: 28 Apr 2014
AbstractforNovel designed polyoxyethylene nonionic surfactant with improved safety and efficiency for anticancer drug delivery | Full Text | References | PDF (1.8 MB)
  • 60 Views
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Article
Evaluation of renal quantitative T2* changes on MRI following administration of ferumoxytol as a T2* contrast agent
Sandeep S Hedgire, Shaunagh McDermott, Gregory R Wojtkiewicz, Seyed Mahdi Abtahi, Mukesh Harisinghani & Jason L Gaglia
Pages: 2101-2107
Published online: 28 Apr 2014
AbstractforEvaluation of renal quantitative T2* changes on MRI following administration of ferumoxytol as a T2* contrast agent | Full Text | References | PDF (1.2 MB)
  • 39 Views
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Article
Low-temperature growth of well-aligned zinc oxide nanorod arrays on silicon substrate and their photocatalytic application
Ameer Azam & Saeed Salem Babkair
Pages: 2109-2115
Published online: 28 Apr 2014
AbstractforLow-temperature growth of well-aligned zinc oxide nanorod arrays on silicon substrate and their photocatalytic application | Full Text | References | PDF (1.3 MB)
  • 63 Views
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Article
Formulation and delivery of itraconazole to the brain using a nanolipid carrier system
Wei Meng Lim, Paruvathanahalli Siddalingam Rajinikanth, Chitneni Mallikarjun & Yew Beng Kang
Pages: 2117-2126
Published online: 02 May 2014
AbstractforFormulation and delivery of itraconazole to the brain using a nanolipid carrier system | Full Text | References | PDF (1.3 MB)
  • 175 Views
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Article
Nanolayer encapsulation of insulin-chitosan complexes improves efficiency of oral insulin delivery
Lei Song, Zheng-liang Zhi & John C Pickup
Pages: 2127-2136
Published online: 02 May 2014
AbstractforNanolayer encapsulation of insulin-chitosan complexes improves efficiency of oral insulin delivery | Full Text | References | PDF (1.3 MB)
  • 93 Views
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Article
Self-assembled or mixed peptide amphiphile micelles from Herpes simplex virus glycoproteins as potential immunomodulatory treatment
Antonella Accardo, Mariateresa Vitiello, Diego Tesauro, Marilena Galdiero, Emiliana Finamore, Francesca Martora, Rosalba Mansi, Paola Ringhieri & Giancarlo Morelli
Pages: 2137-2148
Published online: 07 May 2014
AbstractforSelf-assembled or mixed peptide amphiphile micelles from Herpes simplex virus glycoproteins as potential immunomodulatory treatment | Full Text | References | PDF (623.3 KB)
  • 58 Views
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Article
Preparation of biocompatible heat-labile enterotoxin subunit B-bovine serum albumin nanoparticles for improving tumor-targeted drug delivery via heat-labile enterotoxin subunit B mediation
Liang Zhao, Rongjian Su, Wenyu Cui, Yijie Shi, Liwei Liu & Chang Su
Pages: 2149-2156
Published online: 06 May 2014
AbstractforPreparation of biocompatible heat-labile enterotoxin subunit B-bovine serum albumin nanoparticles for improving tumor-targeted drug delivery via heat-labile enterotoxin subunit B mediation | Full Text | References | PDF (1.5 MB)
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Article
Enhanced uptake and transport of (+)-catechin and (−)-epigallocatechin gallate in niosomal formulation by human intestinal Caco-2 cells
Qinxin Song, Danhui Li, Yongzhi Zhou, Jie Yang, Wanqi Yang, Guohua Zhou & Jingyuan Wen
Pages: 2157-2165
Published online: 08 May 2014
AbstractforEnhanced uptake and transport of (+)-catechin and (−)-epigallocatechin gallate in niosomal formulation by human intestinal Caco-2 cells | Full Text | References | PDF (1.1 MB)
  • 167 Views
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Article
Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting
Peng Ye, Wendian Zhang, Tan Yang, Yao Lu, Miao Lu, Yongkang Gai, Xiang Ma & Guangya Xiang
Pages: 2167-2178
Published online: 07 May 2014
AbstractforFolate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting | Full Text | References | PDF (1.7 MB)
  • 89 Views
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Article
Efficiently engineered cell sheet using a complex of polyethylenimine–alginate nanocomposites plus bone morphogenetic protein 2 gene to promote new bone formation
Han Jin, Kai Zhang, Chunyan Qiao, Anliang Yuan, Daowei Li, Liang Zhao, Ce Shi, Xiaowei Xu, Shilei Ni, Changyu Zheng, Xiaohua Liu, Bai Yang & Hongchen Sun
Pages: 2179-2190
Published online: 07 May 2014
AbstractforEfficiently engineered cell sheet using a complex of polyethylenimine–alginate nanocomposites plus bone morphogenetic protein 2 gene to promote new bone formation | Full Text | References | PDF (3.9 MB)
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Article
Aneuploidogenic effects and DNA oxidation induced in vitro by differently sized gold nanoparticles
Sebastiano Di Bucchianico, Maria Rita Fabbrizi, Silvia Cirillo, Chiara Uboldi, Douglas Gilliland, Eugenia Valsami-Jones & Lucia Migliore
Pages: 2191-2204
Published online: 08 May 2014
AbstractforAneuploidogenic effects and DNA oxidation induced in vitro by differently sized gold nanoparticles | Full Text | References | PDF (2 MB)
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Article
Interaction between immobilized polyelectrolyte complex nanoparticles and human mesenchymal stromal cells
Beatrice Woltmann, Bernhard Torger, Martin Müller & Ute Hempel
Pages: 2205-2215
Published online: 08 May 2014
AbstractforInteraction between immobilized polyelectrolyte complex nanoparticles and human mesenchymal stromal cells | Full Text | References | PDF (3.8 MB)
  • 65 Views
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Article
Gold-functionalized magnetic nanoparticles restrict growth of Pseudomonas aeruginosa
Katarzyna Niemirowicz, Izabela Swiecicka, Agnieszka Z Wilczewska, Iwona Misztalewska, Beata Kalska-Szostko, Kamil Bienias, Robert Bucki & Halina Car
Pages: 2217-2224
Published online: 08 May 2014
AbstractforGold-functionalized magnetic nanoparticles restrict growth of Pseudomonas aeruginosa | Full Text | References | PDF (2 MB)
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Article
An ensemble method approach to investigate kinase-specific phosphorylation sites
Sutapa Datta & Subhasis Mukhopadhyay
Pages: 2225-2239
Published online: 10 May 2014
AbstractforAn ensemble method approach to investigate kinase-specific phosphorylation sites | Full Text | References | PDF (1.6 MB)
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Review

Review Article
Current approaches to enhance CNS delivery of drugs across the brain barriers
Cui-Tao Lu, Ying-Zheng Zhao, Ho Lun Wong, Jun Cai, Lei Peng & Xin-Qiao Tian
Pages: 2241-2257
Published online: 10 May 2014
AbstractforCurrent approaches to enhance CNS delivery of drugs across the brain barriers | Full Text | References | PDF (3 MB)
  • 234 Views
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Corrigendum

Correction
Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs [Corrigendum]
Page: 2259
Published online: 12 May 2014
CitationforAdjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs [Corrigendum] | Full Text | PDF (118.5 KB)
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Original Research

Article
Characterization of rice bran wax policosanol and its nanoemulsion formulation
Aminu Ishaka, Mustapha Umar Imam, Rozi Mahamud, Abu Bakar Zakaria Zuki & Ismail Maznah
Pages: 2261-2269
Published online: 09 May 2014
AbstractforCharacterization of rice bran wax policosanol and its nanoemulsion formulation | Full Text | References | PDF (2.6 MB)
  • 276 Views
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Article
Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity
Yeliz Utku Konca, Kent Kirshenbaum & Ronald N Zuckermann
Pages: 2271-2285
Published online: 10 May 2014
AbstractforNanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity | Full Text | References | PDF (2.2 MB)
  • 67 Views
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Article
Polymersomes containing quantum dots for cellular imaging
Marine Camblin, Pascal Detampel, Helene Kettiger, Dalin Wu, Vimalkumar Balasubramanian & Jörg Huwyler
Pages: 2287-2298
Published online: 12 May 2014
AbstractforPolymersomes containing quantum dots for cellular imaging | Full Text | References | PDF (2.8 MB)
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Article
Effective mucoadhesive liposomal delivery system for risedronate: preparation and in vitro/in vivo characterization
Il-Woo Jung & Hyo-Kyung Han
Pages: 2299-2306
Published online: 12 May 2014
AbstractforEffective mucoadhesive liposomal delivery system for risedronate: preparation and in vitro/in vivo characterization | Full Text | References | PDF (467.9 KB)
  • 78 Views
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Article
Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system
Yanzhi Song, Qingjing Tian, Zhenjun Huang, Di Fan, Zhennan She, Xinrong Liu, Xiaobo Cheng, Bin Yu & Yihui Deng
Pages: 2307-2317
Published online: 12 May 2014
AbstractforSelf-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system | Full Text | References | PDF (1.7 MB)
  • 147 Views
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Article
Oxidative nanopatterning of titanium generates mesoporous surfaces with antimicrobial properties
Fabio Variola, Sylvia Francis Zalzal, Annie Leduc, Jean Barbeau & Antonio Nanci
Pages: 2319-2325
Published online: 13 May 2014
AbstractforOxidative nanopatterning of titanium generates mesoporous surfaces with antimicrobial properties | Full Text | References | PDF (2.8 MB)
  • 65 Views
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Article
Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion
Shu-min Ding, Zhen-hai Zhang, Jie Song, Xu-dong Cheng, Jun Jiang & Xiao-bin Jia
Pages: 2327-2333
Published online: 13 May 2014
AbstractforEnhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion | Full Text | References | PDF (1.5 MB)
  • 146 Views
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Article
Electrospun gelatin/PCL and collagen/PLCL scaffolds for vascular tissue engineering
Wei Fu, Zhenling Liu, Bei Feng, Renjie Hu, Xiaomin He, Hao Wang, Meng Yin, Huimin Huang, Haibo Zhang & Wei Wang
Pages: 2335-2344
Published online: 13 May 2014
AbstractforElectrospun gelatin/PCL and collagen/PLCL scaffolds for vascular tissue engineering | Full Text | References | PDF (3.7 MB)
  • 507 Views
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Article
Enhancement of radiotherapy efficacy by miR-200c-loaded gelatinase-stimuli PEG-Pep-PCL nanoparticles in gastric cancer cells
Fang-bo Cui, Qin Liu, Ru-Tian Li, Jie Shen, Pu-yuan Wu, Li-Xia Yu, Wen-jing Hu, Feng-lei Wu, Chun-Ping Jiang, Guo-feng Yue, Xiao-Ping Qian, Xi-Qun Jiang & Bao-Rui Liu
Pages: 2345-2358
Published online: 13 May 2014
AbstractforEnhancement of radiotherapy efficacy by miR-200c-loaded gelatinase-stimuli PEG-Pep-PCL nanoparticles in gastric cancer cells | Full Text | References | PDF (2.3 MB)
  • 46 Views
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Article
Physicochemical features and transfection properties of chitosan/poloxamer 188/poly(D,L-lactide-co-glycolide) nanoplexes
Donato Cosco, Cinzia Federico, Jessica Maiuolo, Stefania Bulotta, Roberto Molinaro, Donatella Paolino, Pierfrancesco Tassone & Massimo Fresta
Pages: 2359-2372
Published online: 15 May 2014
AbstractforPhysicochemical features and transfection properties of chitosan/poloxamer 188/poly(D,L-lactide-co-glycolide) nanoplexes | Full Text | References | PDF (5.6 MB)
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Article
Biological augmentation of rotator cuff repair using bFGF-loaded electrospun poly(lactide-co-glycolide) fibrous membranes
Song Zhao, Jingwen Zhao, Shikui Dong, Xiaoqiao Huangfu, Bin Li, Huilin Yang, Jinzhong Zhao & Wenguo Cui
Pages: 2373-2385
Published online: 14 May 2014
AbstractforBiological augmentation of rotator cuff repair using bFGF-loaded electrospun poly(lactide-co-glycolide) fibrous membranes | Full Text | References | PDF (3.1 MB)
  • 95 Views
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Article
Magnesium ion implantation on a micro/nanostructured titanium surface promotes its bioactivity and osteogenic differentiation function
Guifang Wang, Jinhua Li, Wenjie Zhang, Lianyi Xu, Hongya Pan, Jin Wen, Qianju Wu, Wenjun She, Ting Jiao, Xuanyong Liu & Xinquan Jiang
Pages: 2387-2398
Published online: 21 May 2014
AbstractforMagnesium ion implantation on a micro/nanostructured titanium surface promotes its bioactivity and osteogenic differentiation function | Full Text | References | PDF (3.6 MB)
  • 137 Views
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Review

Review Article
Nanosilver particles in medical applications: synthesis, performance, and toxicity
Liangpeng Ge, Qingtao Li, Meng Wang, Jun Ouyang, Xiaojian Li & Malcolm MQ Xing
Pages: 2399-2407
Published online: 16 May 2014
AbstractforNanosilver particles in medical applications: synthesis, performance, and toxicity | Full Text | References | PDF (1.1 MB)
  • 863 Views
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Original Research

Article
Nanoparticles containing allotropes of carbon have genotoxic effects on glioblastoma multiforme cells
Mateusz Hinzmann, Sławomir Jaworski, Marta Kutwin, Joanna Jagiełło, Rafał Koziński, Mateusz Wierzbicki, Marta Grodzik, Ludwika Lipińska, Ewa Sawosz & Andrè Chwalibog
Pages: 2409-2417
Published online: 15 May 2014
AbstractforNanoparticles containing allotropes of carbon have genotoxic effects on glioblastoma multiforme cells | Full Text | References | PDF (2.5 MB)
  • 80 Views
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Article
Antioxidative nanofullerol prevents intervertebral disk degeneration
Xinlin Yang, Li Jin, Lu Yao, Francis H Shen, Adam L Shimer & Xudong Li
Pages: 2419-2430
Published online: 15 May 2014
AbstractforAntioxidative nanofullerol prevents intervertebral disk degeneration | Full Text | References | PDF (1.6 MB)
  • 57 Views
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Article
Biosynthesis of silver nanoparticles using Acacia leucophloea extract and their antibacterial activity
Kasi Murugan, Balakrishnan Senthilkumar, Duraisamy Senbagam & Saleh Al-Sohaibani
Pages: 2431-2438
Published online: 15 May 2014
AbstractforBiosynthesis of silver nanoparticles using Acacia leucophloea extract and their antibacterial activity | Full Text | References | PDF (2.5 MB)
  • 455 Views
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Article
Interaction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber mats
Rajamani Lakshminarayanan, Radhakrishnan Sridhar, Xian Jun Loh, Muruganantham Nandhakumar, Veluchamy Amutha Barathi, Madhaiyan Kalaipriya, Jia Lin Kwan, Shou Ping Liu, Roger Wilmer Beuerman & Seeram Ramakrishna
Pages: 2439-2458
Published online: 23 May 2014
AbstractforInteraction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber mats | Full Text | References | PDF (7.5 MB)
  • 111 Views
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Article
Optimal energy for cell radiosensitivity enhancement by gold nanoparticles using synchrotron-based monoenergetic photon beams
Wan Nordiana Rahman, Stéphanie Corde, Naoto Yagi, Siti Aishah Abdul Aziz, Nathan Annabell & Moshi Geso
Pages: 2459-2467
Published online: 19 May 2014
AbstractforOptimal energy for cell radiosensitivity enhancement by gold nanoparticles using synchrotron-based monoenergetic photon beams | Full Text | References | PDF (1.4 MB)
  • 130 Views
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Article
Silver nanoparticles promote osteogenic differentiation of human urine-derived stem cells at noncytotoxic concentrations
Hui Qin, Chen Zhu, Zhiquan An, Yao Jiang, Yaochao Zhao, Jiaxin Wang, Xin Liu, Bing Hui, Xianlong Zhang & Yang Wang
Pages: 2469-2478
Published online: 20 May 2014
AbstractforSilver nanoparticles promote osteogenic differentiation of human urine-derived stem cells at noncytotoxic concentrations | Full Text | References | PDF (2.4 MB)
  • 135 Views
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Article
Cytotoxic effect of magnetic iron oxide nanoparticles synthesized via seaweed aqueous extract
Farideh Namvar, Heshu Sulaiman Rahman, Rosfarizan Mohamad, Javad Baharara, Mahnaz Mahdavi, Elaheh Amini, Max Stanley Chartrand & Swee Keong Yeap
Pages: 2479-2488
Published online: 19 May 2014
AbstractforCytotoxic effect of magnetic iron oxide nanoparticles synthesized via seaweed aqueous extract | Full Text | References | PDF (3.3 MB)
  • 336 Views
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Article
One-pot synthesis of magnetic nanoclusters enabling atherosclerosis-targeted magnetic resonance imaging
Aastha Kukreja, Eun-Kyung Lim, Byunghoon Kang, Yuna Choi, Taeksu Lee, Jin-Suck Suh, Yong-Min Huh & Seungjoo Haam
Pages: 2489-2498
Published online: 21 May 2014
AbstractforOne-pot synthesis of magnetic nanoclusters enabling atherosclerosis-targeted magnetic resonance imaging | Full Text | References | PDF (2.9 MB)
  • 45 Views
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Article
Osteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in vitro
Giuseppe Maria de Peppo, Hossein Agheli, Camilla Karlsson, Karin Ekström, Helena Brisby, Maria Lennerås, Stefan Gustafsson, Peter Sjövall, Anna Johansson, Eva Olsson, Jukka Lausmaa, Peter Thomsen & Sarunas Petronis
Pages: 2499-2515
Published online: 22 May 2014
AbstractforOsteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in vitro | Full Text | References | PDF (3.7 MB)
  • 68 Views
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Article
Optimization and evaluation of a thermoresponsive ophthalmic in situ gel containing curcumin-loaded albumin nanoparticles
Jie Lou, Wenjing Hu, Rui Tian, Hua Zhang, Yuntao Jia, Jingqing Zhang & Liangke Zhang
Pages: 2517-2525
Published online: 21 May 2014
AbstractforOptimization and evaluation of a thermoresponsive ophthalmic in situ gel containing curcumin-loaded albumin nanoparticles | Full Text | References | PDF (1.2 MB)
  • 356 Views
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Article
Iodinated oil-loaded, fluorescent mesoporous silica-coated iron oxide nanoparticles for magnetic resonance imaging/computed tomography/fluorescence trimodal imaging
Sihan Xue, Yao Wang, Mengxing Wang, Lu Zhang, Xiaoxia Du, Hongchen Gu & Chunfu Zhang
Pages: 2527-2538
Published online: 21 May 2014
AbstractforIodinated oil-loaded, fluorescent mesoporous silica-coated iron oxide nanoparticles for magnetic resonance imaging/computed tomography/fluorescence trimodal imaging | Full Text | References | PDF (2.8 MB)
  • 113 Views
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Review

Review Article
Nanomedicine for drug targeting: strategies beyond the enhanced permeability and retention effect
Hayley Nehoff, Neha N Parayath, Laura Domanovitch, Sebastien Taurin & Khaled Greish
Pages: 2539-2555
Published online: 22 May 2014
AbstractforNanomedicine for drug targeting: strategies beyond the enhanced permeability and retention effect | Full Text | References | PDF (2.7 MB)
  • 297 Views
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Original Research

Article
Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium
Gábor Raffai, Byungkuk Kim, Sanga Park, Gilson Khang, Dongwon Lee & Paul M Vanhoutte
Pages: 2557-2566
Published online: 21 May 2014
AbstractforCinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium | Full Text | References | PDF (1,015.4 KB)
  • 76 Views
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Corrigendum

Correction
Probing the mechanical properties of TNF-α stimulated endothelial cell with atomic force microscopy [Corrigendum]
Page: 2567
Published online: 23 May 2014
CitationforProbing the mechanical properties of TNF-α stimulated endothelial cell with atomic force microscopy [Corrigendum] | Full Text | References | PDF (104.9 KB)
  • 38 Views
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Original Research

Article
Transparent, biocompatible nanostructured surfaces for cancer cell capture and culture
Boran Cheng, Zhaobo He, Libo Zhao, Yuan Fang, Yuanyuan Chen, Rongxiang He, Fangfang Chen, Haibin Song, Yuliang Deng, Xingzhong Zhao & Bin Xiong
Pages: 2569-2580
Published online: 22 May 2014
AbstractforTransparent, biocompatible nanostructured surfaces for cancer cell capture and culture | Full Text | References | PDF (3.6 MB)
  • 54 Views
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Article
Manganese-containing Prussian blue nanoparticles for imaging of pediatric brain tumors
Matthieu F Dumont, Sridevi Yadavilli, Raymond W Sze, Javad Nazarian & Rohan Fernandes
Pages: 2581-2595
Published online: 23 May 2014
AbstractforManganese-containing Prussian blue nanoparticles for imaging of pediatric brain tumors | Full Text | References | PDF (5.7 MB)
  • 91 Views
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Article
Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles
Núria Mas, Irene Galiana, Silvia Hurtado, Laura Mondragón, Andrea Bernardos, Félix Sancenón, María D Marcos, Pedro Amorós, Nuria Abril-Utrillas, Ramón Martínez-Máñez & José Ramón Murguía
Pages: 2597-2606
Published online: 23 May 2014
AbstractforEnhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles | Full Text | References | PDF (2.1 MB)
  • 69 Views
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Article
In situ precipitation: a novel approach for preparation of iron-oxide magnetoliposomes
Shudong Xia, Peng Li, Qiang Chen, Malik Armah, Xiaoying Ying, Jian Wu & Jiangtao Lai
Pages: 2607-2617
Published online: 23 May 2014
AbstractforIn situ precipitation: a novel approach for preparation of iron-oxide magnetoliposomes | Full Text | References | PDF (1 MB)
  • 39 Views
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Article
Amplified voltammetric detection of glycoproteins using 4-mercaptophenylboronic acid/biotin-modified multifunctional gold nanoparticles as labels
Lin Liu, Yun Xing, Hui Zhang, Ruili Liu, Huijing Liu & Ning Xia
Pages: 2619-2626
Published online: 27 May 2014
AbstractforAmplified voltammetric detection of glycoproteins using 4-mercaptophenylboronic acid/biotin-modified multifunctional gold nanoparticles as labels | Full Text | References | PDF (996.5 KB)
  • 88 Views
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Article
Liposomes versus metallic nanostructures: differences in the process of knowledge translation in cancer
David Fajardo-Ortiz, Luis Duran, Laura Moreno, Héctor Ochoa & Víctor M Castaño
Pages: 2627-2634
Published online: 26 May 2014
AbstractforLiposomes versus metallic nanostructures: differences in the process of knowledge translation in cancer | Full Text | References | PDF (1.9 MB)
  • 1662 Views
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Article
Rapid efficient synthesis and characterization of silver, gold, and bimetallic nanoparticles from the medicinal plant Plumbago zeylanica and their application in biofilm control
Gayatri R Salunke, Sougata Ghosh, RJ Santosh Kumar, Samiksha Khade, Priya Vashisth, Trupti Kale, Snehal Chopade, Vikas Pruthi, Gopal Kundu, Jayesh R Bellare & Balu A Chopade
Pages: 2635-2653
Published online: 27 May 2014
AbstractforRapid efficient synthesis and characterization of silver, gold, and bimetallic nanoparticles from the medicinal plant Plumbago zeylanica and their application in biofilm control | Full Text | References | PDF (6.3 MB)
  • 602 Views
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Article
Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes
Xiaojin Chen, Ting Wang, Mengmeng Lu, Luyan Zhu, Yan Wang & WenZhong Zhou
Pages: 2655-2664
Published online: 27 May 2014
AbstractforPreparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes | Full Text | References | PDF (1.2 MB)
  • 66 Views
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Article
Mesoporous magnesium silicate-incorporated poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) bioactive composite beneficial to osteoblast behaviors
Yunfei Niu, Wei Dong, Han Guo, Yuhu Deng, Lieping Guo, Xiaofei An, Dawei He, Jie Wei & Ming Li
Pages: 2665-2675
Published online: 27 May 2014
AbstractforMesoporous magnesium silicate-incorporated poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) bioactive composite beneficial to osteoblast behaviors | Full Text | References | PDF (4.7 MB)
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Article
Increased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson’s disease
Enara Herrán, Catalina Requejo, Jose Angel Ruiz-Ortega, Asier Aristieta, Manoli Igartua, Harkaitz Bengoetxea, Luisa Ugedo, Jose Luis Pedraz, Jose Vicente Lafuente & Rosa Maria Hernández
Pages: 2677-2687
Published online: 27 May 2014
AbstractforIncreased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson’s disease | Full Text | References | PDF (3.2 MB)
  • 76 Views
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Article
Calcifying nanoparticles promote mineralization in vascular smooth muscle cells: implications for atherosclerosis
Larry W Hunter, Jon E Charlesworth, Sam Yu, John C Lieske & Virginia M Miller
Pages: 2689-2698
Published online: 27 May 2014
AbstractforCalcifying nanoparticles promote mineralization in vascular smooth muscle cells: implications for atherosclerosis | Full Text | References | PDF (3.1 MB)
  • 70 Views
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Article
Effect of additive particles on mechanical, thermal, and cell functioning properties of poly(methyl methacrylate) cement
Morshed Khandaker, Melville B Vaughan, Tracy L Morris, Jeremiah J White & Zhaotong Meng
Pages: 2699-2712
Published online: 27 May 2014
AbstractforEffect of additive particles on mechanical, thermal, and cell functioning properties of poly(methyl methacrylate) cement | Full Text | References | PDF (7.3 MB)
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Review

Review Article
Multifunctional materials for bone cancer treatment
Catarina Marques, José MF Ferreira, Ecaterina Andronescu, Denisa Ficai, Maria Sonmez & Anton Ficai
Pages: 2713-2725
Published online: 28 May 2014
AbstractforMultifunctional materials for bone cancer treatment | Full Text | References | PDF (1.3 MB)
  • 307 Views
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Methodology

Article
Synthesis and characterization of different immunogenic viral nanoconstructs from rotavirus VP6 inner capsid protein
Francesca Bugli, Valeria Caprettini, Margherita Cacaci, Cecilia Martini, Francesco Paroni Sterbini, Riccardo Torelli, Stefano Della Longa, Massimiliano Papi, Valentina Palmieri, Bruno Giardina, Brunella Posteraro, Maurizio Sanguinetti & Alessandro Arcovito
Pages: 2727-2739
Published online: 30 May 2014
AbstractforSynthesis and characterization of different immunogenic viral nanoconstructs from rotavirus VP6 inner capsid protein | Full Text | References | PDF (2.9 MB)
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Original Research

Article
Preclinical studies of N3-O-toluyl-fluorouracil-loaded lipid-based nanosuspensions in H22-bearing mice
Juan Zhang, Min Li, Zhihong Liu, Lili Wang, Yongjun Liu & Na Zhang
Pages: 2741-2751
Published online: 29 May 2014
AbstractforPreclinical studies of N3-O-toluyl-fluorouracil-loaded lipid-based nanosuspensions in H22-bearing mice | Full Text | References | PDF (959.1 KB)
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Article
Mussel-inspired human gelatin nanocoating for creating biologically adhesive surfaces
Xi Yang, Liping Zhu, Seiichi Tada, Di Zhou, Takashi Kitajima, Takashi Isoshima, Yasuhiro Yoshida, Mariko Nakamura, Weiqun Yan & Yoshihiro Ito
Pages: 2753-2765
Published online: 29 May 2014
AbstractforMussel-inspired human gelatin nanocoating for creating biologically adhesive surfaces | Full Text | References | PDF (1.6 MB)
  • 73 Views
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Article
Liver cancer cells: targeting and prolonged-release drug carriers consisting of mesoporous silica nanoparticles and alginate microspheres
Yu-Te Liao, Chia-Hung Liu, Jiashing Yu & Kevin C-W Wu
Pages: 2767-2778
Published online: 05 Jun 2014
AbstractforLiver cancer cells: targeting and prolonged-release drug carriers consisting of mesoporous silica nanoparticles and alginate microspheres | Full Text | References | PDF (1.9 MB)
  • 125 Views
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Article
Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation
Abderrahim Nemmar, Sulayma Albarwani, Sumaya Beegam, Priya Yuvaraju, Javed Yasin, Samir Attoub & Badreldin H Ali
Pages: 2779-2789
Published online: 02 Jun 2014
AbstractforAmorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation | Full Text | References | PDF (642.4 KB)
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Methodology

Article
Detection of PLGA-based nanoparticles at a single-cell level by synchrotron radiation FTIR spectromicroscopy and correlation with X-ray fluorescence microscopy
Lorella Pascolo, Barbara Bortot, Nuria Benseny-Cases, Alessandra Gianoncelli, Giovanni Tosi, Barbara Ruozi, Clara Rizzardi, Eleonora De Martino, Maria Angela Vandelli & Giovanni Maria Severini
Pages: 2791-2801
Published online: 07 Jun 2014
AbstractforDetection of PLGA-based nanoparticles at a single-cell level by synchrotron radiation FTIR spectromicroscopy and correlation with X-ray fluorescence microscopy | Full Text | References | PDF (2.6 MB)
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Original Research

Article
Poly(styrene)-b-poly(DL-lactide) copolymer-based nanoparticles for anticancer drug delivery
Jae-Young Lee, Jung Sun Kim, Hyun-Jong Cho & Dae-Duk Kim
Pages: 2803-2813
Published online: 03 Jun 2014
AbstractforPoly(styrene)-b-poly(DL-lactide) copolymer-based nanoparticles for anticancer drug delivery | Full Text | References | PDF (2.4 MB)
  • 52 Views
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Article
Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties
Viviana Marzaioli, Juan Antonio Aguilar-Pimentel, Ingrid Weichenmeier, Georg Luxenhofer, Martin Wiemann, Robert Landsiedel, Wendel Wohlleben, Stefanie Eiden, Martin Mempel, Heidrun Behrendt, Carsten Schmidt-Weber, Jan Gutermuth & Francesca Alessandrini
Pages: 2815-2832
Published online: 05 Jun 2014
AbstractforSurface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties | Full Text | References | PDF (3.9 MB)
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Article
Sequential optimization of methotrexate encapsulation in micellar nano-networks of polyethyleneimine ionomer containing redox-sensitive cross-links
Samira Sadat Abolmaali, Ali Tamaddon, Gholamhossein Yousefi, Katayoun Javidnia & Rasoul Dinarvand
Pages: 2833-2848
Published online: 06 Jun 2014
AbstractforSequential optimization of methotrexate encapsulation in micellar nano-networks of polyethyleneimine ionomer containing redox-sensitive cross-links | Full Text | References | PDF (877.3 KB)
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Article
Enhanced cellular uptake of maleimide-modified liposomes via thiol-mediated transport
Tianshu Li & Shinji Takeoka
Pages: 2849-2861
Published online: 05 Jun 2014
AbstractforEnhanced cellular uptake of maleimide-modified liposomes via thiol-mediated transport | Full Text | References | PDF (2.1 MB)
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Review

Review Article
Nanoparticles for hyperthermic therapy: synthesis strategies and applications in glioblastoma
Jyoti Verma, Sumit Lal & Cornelis JF Van Noorden
Pages: 2863-2877
Published online: 10 Jun 2014
AbstractforNanoparticles for hyperthermic therapy: synthesis strategies and applications in glioblastoma | Full Text | References | PDF (2 MB)
  • 228 Views
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Original Research

Article
TAT-LHRH conjugated low molecular weight chitosan as a gene carrier specific for hepatocellular carcinoma cells
Lanxia Liu, Xia Dong, Dunwan Zhu, Liping Song, Hailing Zhang & Xigang G Leng
Pages: 2879-2889
Published online: 10 Jun 2014
AbstractforTAT-LHRH conjugated low molecular weight chitosan as a gene carrier specific for hepatocellular carcinoma cells | Full Text | References | PDF (2.9 MB)
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Article
SiO2 nanoparticle-induced impairment of mitochondrial energy metabolism in hepatocytes directly and through a Kupffer cell-mediated pathway in vitro
Yang Xue, Qingqing Chen, Tingting Ding & Jiao Sun
Pages: 2891-2903
Published online: 12 Jun 2014
AbstractforSiO2 nanoparticle-induced impairment of mitochondrial energy metabolism in hepatocytes directly and through a Kupffer cell-mediated pathway in vitro | Full Text | References | PDF (2.4 MB)
  • 75 Views
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Article
Enhanced and selective delivery of enzyme therapy to 9L-glioma tumor via magnetic targeting of PEG-modified, β-glucosidase-conjugated iron oxide nanoparticles
Jie Zhou, Jian Zhang & Wenxi Gao
Pages: 2905-2917
Published online: 10 Jun 2014
AbstractforEnhanced and selective delivery of enzyme therapy to 9L-glioma tumor via magnetic targeting of PEG-modified, β-glucosidase-conjugated iron oxide nanoparticles | Full Text | References | PDF (2.7 MB)
  • 65 Views
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Article
N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors
Chun-ge Zhang, Qiao-ling Zhu, Yi Zhou, Yang Liu, Wei-liang Chen, Zhi-Qiang Yuan, Shu-di Yang, Xiao-feng Zhou, Ai-jun Zhu, Xue-nong Zhang & Yong Jin
Pages: 2919-2932
Published online: 13 Jun 2014
AbstractforN-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors | Full Text | References | PDF (4.3 MB)
  • 57 Views
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Article
Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy
Sumit Arora, Suresh K Swaminathan, Ameya Kirtane, Sanjeev K Srivastava, Arun Bhardwaj, Seema Singh, Jayanth Panyam & Ajay P Singh
Pages: 2933-2942
Published online: 18 Jun 2014
AbstractforSynthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy | Full Text | References | PDF (2.7 MB)
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Article
Nanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers
Ibrahim Elsayed, Aly Ahmed Abdelbary & Ahmed Hassen Elshafeey
Pages: 2943-2953
Published online: 17 Jun 2014
AbstractforNanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers | Full Text | References | PDF (2.1 MB)
  • 142 Views
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Article
Accurate sequential detection of primary tumor and metastatic lymphatics using a temperature-induced phase transition nanoparticulate system
Keun Sang Oh, Ji Young Yhee, Dong-Eun Lee, Kwangmeyung Kim, Ick Chan Kwon, Jae Hong Seo, Sang Yoon Kim & Soon Hong Yuk
Pages: 2955-2965
Published online: 18 Jun 2014
AbstractforAccurate sequential detection of primary tumor and metastatic lymphatics using a temperature-induced phase transition nanoparticulate system | Full Text | References | PDF (5.3 MB)
  • 45 Views
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Article
Delivery of multipurpose prevention drug combinations from electrospun nanofibers using composite microarchitectures
Anna K Blakney, Emily A Krogstad, Yonghou H Jiang & Kim A Woodrow
Pages: 2967-2978
Published online: 17 Jun 2014
AbstractforDelivery of multipurpose prevention drug combinations from electrospun nanofibers using composite microarchitectures | Full Text | References | PDF (6.9 MB)
  • 95 Views
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Article
Controlled release of raloxifene by nanoencapsulation: effect on in vitro antiproliferative activity of human breast cancer cells
Márcia Camponogara Fontana, Aline Beckenkamp, Andréia Buffon & Ruy Carlos Ruver Beck
Pages: 2979-2991
Published online: 17 Jun 2014
AbstractforControlled release of raloxifene by nanoencapsulation: effect on in vitro antiproliferative activity of human breast cancer cells | Full Text | References | PDF (979.9 KB)
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Article
Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles
Jing-Jing Yao, Yong-Zhong Du, Hong Yuan, Jian You & Fu-Qiang Hu
Pages: 2993-3003
Published online: 18 Jun 2014
AbstractforEfficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles | Full Text | References | PDF (4.4 MB)
  • 51 Views
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Article
Assessment of antitumor activity and acute peripheral neuropathy of 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016)
Takayoshi Ueno, Kazuhira Endo, Kiyomi Hori, Noriyuki Ozaki, Akira Tsuji, Satoru Kondo, Naohiro Wakisaka, Shigeyuki Murono, Kazunori Kataoka, Yasuki Kato & Tomokazu Yoshizaki
Pages: 3005-3012
Published online: 19 Jun 2014
AbstractforAssessment of antitumor activity and acute peripheral neuropathy of 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) | Full Text | References | PDF (431.4 KB)
  • 88 Views
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Article
Magnetic field enhanced convective diffusion of iron oxide nanoparticles in an osmotically disrupted cell culture model of the blood–brain barrier
Zhizhi Sun, Matthew Worden, Yaroslav Wroczynskyj, Vinith Yathindranath, Johan van Lierop, Torsten Hegmann & Donald W Miller
Pages: 3013-3026
Published online: 20 Jun 2014
AbstractforMagnetic field enhanced convective diffusion of iron oxide nanoparticles in an osmotically disrupted cell culture model of the blood–brain barrier | Full Text | References | PDF (4.3 MB)
  • 117 Views
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Article
Electrospun vancomycin-loaded coating on titanium implants for the prevention of implant-associated infections
Li Zhang, Junwei Yan, Zhaowei Yin, Cheng Tang, Yang Guo, Dong Li, Bo Wei, Yan Xu, Qiangrong Gu & Liming Wang
Pages: 3027-3036
Published online: 23 Jun 2014
AbstractforElectrospun vancomycin-loaded coating on titanium implants for the prevention of implant-associated infections | Full Text | References | PDF (9.5 MB)
  • 134 Views
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Article
In vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles
Giovanni Baldi, Costanza Ravagli, Filippo Mazzantini, George Loudos, Jaume Adan, Marc Masa, Dimitrios Psimadas, Eirini A Fragogeorgi, Erica Locatelli, Claudia Innocenti, Claudio Sangregorio & Mauro Comes Franchini
Pages: 3037-3056
Published online: 24 Jun 2014
AbstractforIn vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles | Full Text | References | PDF (5.2 MB)
  • 60 Views
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Article
Safety evaluation of poly(lactic-co-glycolic acid)/poly(lactic-acid) microspheres through intravitreal injection in rabbits
Xianfang Rong, Weien Yuan, Yi Lu & Xiaofen Mo
Pages: 3057-3068
Published online: 24 Jun 2014
AbstractforSafety evaluation of poly(lactic-co-glycolic acid)/poly(lactic-acid) microspheres through intravitreal injection in rabbits | Full Text | References | PDF (10.1 MB)
  • 58 Views
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Article
A new approach for noninvasive transdermal determination of blood uric acid levels
Congo Tak-Shing Ching, Kok-Khun Yong, Yan-Dong Yao, Huan-Ting Shen, Shiu-Man Hsieh, Deng-Yun Jheng, Tai-Ping Sun & Hsiu-Li Shieh
Pages: 3069-3076
Published online: 28 Jun 2014
AbstractforA new approach for noninvasive transdermal determination of blood uric acid levels | Full Text | References | PDF (1,009.2 KB)
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Article
Sinoporphyrin sodium, a novel sensitizer, triggers mitochondrial-dependent apoptosis in ECA-109 cells via production of reactive oxygen species
Haiping Wang, Xiaobing Wang, Shaoliang Zhang, Pan Wang, Kun Zhang & Quanhong Liu
Pages: 3077-3090
Published online: 25 Jun 2014
AbstractforSinoporphyrin sodium, a novel sensitizer, triggers mitochondrial-dependent apoptosis in ECA-109 cells via production of reactive oxygen species | Full Text | References | PDF (3.6 MB)
  • 72 Views
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Article
Antitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX) on B16-F10 melanoma
Ruo Du, Ting Zhong, Wei-Qiang Zhang, Ping Song, Wen-Ding Song, Yang Zhao, Chao Wang, Yi-Qun Tang, Xuan Zhang & Qiang Zhang
Pages: 3091-3105
Published online: 24 Jun 2014
AbstractforAntitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX) on B16-F10 melanoma | Full Text | References | PDF (6.4 MB)
  • 148 Views
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Article
Preparation and characterization of Tamoxifen citrate loaded nanoparticles for breast cancer therapy
Ruma Maji, Niladri Shekhar Dey, Bhabani Sankar Satapathy, Biswajit Mukherjee & Subhasish Mondal
Pages: 3107-3118
Published online: 25 Jun 2014
AbstractforPreparation and characterization of Tamoxifen citrate loaded nanoparticles for breast cancer therapy | Full Text | References | PDF (5.3 MB)
  • 509 Views
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Article
Entrapment of curcumin into monoolein-based liquid crystalline nanoparticle dispersion for enhancement of stability and anticancer activity
Rengarajan Baskaran, Thiagarajan Madheswaran, Pasupathi Sundaramoorthy, Hwan Mook Kim & Bong Kyu Yoo
Pages: 3119-3130
Published online: 26 Jun 2014
AbstractforEntrapment of curcumin into monoolein-based liquid crystalline nanoparticle dispersion for enhancement of stability and anticancer activity | Full Text | References | PDF (3.2 MB)
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Short Report

Brief Report
Lubricin as a novel nanostructured protein coating to reduce fibroblast density
George Ejiofor Aninwene II, Zifan Yang, Vishnu Ravi, Gregory D Jay & Thomas J Webster
Pages: 3131-3135
Published online: 25 Jun 2014
AbstractforLubricin as a novel nanostructured protein coating to reduce fibroblast density | Full Text | References | PDF (1.2 MB)
  • 42 Views
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Original Research

Article
Anticancer nanodelivery system with controlled release property based on protocatechuate–zinc layered hydroxide nanohybrid
Farahnaz Barahuie, Mohd Zobir Hussein, Shafinaz Abd Gani, Sharida Fakurazi & Zulkarnain Zainal
Pages: 3137-3149
Published online: 26 Jun 2014
AbstractforAnticancer nanodelivery system with controlled release property based on protocatechuate–zinc layered hydroxide nanohybrid | Full Text | References | PDF (3.6 MB)
  • 68 Views
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Article
Chitosan gel containing polymeric nanocapsules: a new formulation for vaginal drug delivery
Luiza A Frank, Giuseppina Sandri, Francesca D’Autilia, Renata V Contri, Maria Cristina Bonferoni, Carla Caramella, Alejandro G Frank, Adriana R Pohlmann & Silvia S Guterres
Pages: 3151-3161
Published online: 28 Jun 2014
AbstractforChitosan gel containing polymeric nanocapsules: a new formulation for vaginal drug delivery | Full Text | References | PDF (1.8 MB)
  • 245 Views
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Article
Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier
Yu-Shiang Peng, Po-Liang Lai, Sydney Peng, His-Chin Wu, Siang Yu, Tsan-Yun Tseng, Li-Fang Wang & I-Ming Chu
Pages: 3163-3174
Published online: 28 Jun 2014
AbstractforGlial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier | Full Text | References | PDF (3.6 MB)
  • 68 Views
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Article
Stepwise encapsulation and controlled two-stage release system for cis-Diamminediiodoplatinum
Yun Chen, Qian Li & Qingsheng Wu
Pages: 3175-3182
Published online: 28 Jun 2014
AbstractforStepwise encapsulation and controlled two-stage release system for cis-Diamminediiodoplatinum | Full Text | References | PDF (1.9 MB)
  • 37 Views
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Article
Novel gramicidin formulations in cationic lipid as broad-spectrum microbicidal agents
Danielle AMT Ragioto, Letícia DM Carrasco & Ana M Carmona-Ribeiro
Pages: 3183-3192
Published online: 30 Jun 2014
AbstractforNovel gramicidin formulations in cationic lipid as broad-spectrum microbicidal agents | Full Text | References | PDF (1.5 MB)
  • 78 Views
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Article
Novel flower-shaped albumin particles as controlled-release carriers for drugs to penetrate the round-window membrane
Zhan Yu, Min Yu, Zhimin Zhou, Zhibao Zhang, Bo Du & Qingqing Xiong
Pages: 3193-3201
Published online: 01 Jul 2014
AbstractforNovel flower-shaped albumin particles as controlled-release carriers for drugs to penetrate the round-window membrane | Full Text | References | PDF (4.4 MB)
  • 50 Views
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Article
MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer
Marta Passadouro, Maria C Pedroso de Lima & Henrique Faneca
Pages: 3203-3217
Published online: 03 Jul 2014
AbstractforMicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer | Full Text | References | PDF (1.5 MB)
  • 75 Views
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Article
Effect of nanostructured TiO2 crystal phase on photoinduced apoptosis of breast cancer epithelial cells
Nefeli Lagopati, Effie-Photini Tsilibary, Polycarpos Falaras, Panagiota Papazafiri, Evangelia A Pavlatou, Eleni Kotsopoulou & Paraskevi Kitsiou
Pages: 3219-3230
Published online: 03 Jul 2014
AbstractforEffect of nanostructured TiO2 crystal phase on photoinduced apoptosis of breast cancer epithelial cells | Full Text | References | PDF (2 MB)
  • 122 Views
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Article
Elucidating the role of free polycationic chains in polycation gene carriers by free chains of polyethylenimine or N,N,N-trimethyl chitosan plus a certain polyplex
Tao Xu, Wei Liu, Suhang Wang & Zhengzhong Shao
Pages: 3231-3245
Published online: 03 Jul 2014
AbstractforElucidating the role of free polycationic chains in polycation gene carriers by free chains of polyethylenimine or N,N,N-trimethyl chitosan plus a certain polyplex | Full Text | References | PDF (6.4 MB)
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Letter

Letter
Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
Seiji Kojima, Andrei Cucuianu, Yoshiyuki Takahashi, Ioana Berindan-Neagoe, Ioan-Stefan Florian, Delia Dima & Ciprian Tomuleasa
Pages: 3247-3248
Published online: 04 Jul 2014
CitationforDose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies | Full Text | References | PDF (119.2 KB)
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Original Research

Article
Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries
Pritesh P Jain, Regina Leber, Chandran Nagaraj, Gerd Leitinger, Bernhard Lehofer, Horst Olschewski, Andrea Olschewski, Ruth Prassl & Leigh M Marsh
Pages: 3249-3261
Published online: 07 Jul 2014
AbstractforLiposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries | Full Text | References | PDF (3.2 MB)
  • 82 Views
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Article
Abdominal closure reinforcement by using polypropylene mesh functionalized with poly-ε-caprolactone nanofibers and growth factors for prevention of incisional hernia formation
Martin Plencner, Barbora East, Zbyněk Tonar, Martin Otáhal, Eva Prosecká, Michala Rampichová, Tomáš Krejčí, Andrej Litvinec, Matej Buzgo, Andrea Míčková, Alois Nečas, Jiří Hoch & Evžen Amler
Pages: 3263-3277
Published online: 09 Jul 2014
AbstractforAbdominal closure reinforcement by using polypropylene mesh functionalized with poly-ε-caprolactone nanofibers and growth factors for prevention of incisional hernia formation | Full Text | References | PDF (11.9 MB)
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Article
Nanoformulated cell-penetrating survivin mutant and its dual actions
Bhasker Sriramoju, Rupinder K Kanwar & Jagat R Kanwar
Pages: 3279-3298
Published online: 10 Jul 2014
AbstractforNanoformulated cell-penetrating survivin mutant and its dual actions | Full Text | References | PDF (9.5 MB)
  • 38 Views
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Article
Manganese ferrite-based nanoparticles induce ex vivo, but not in vivo, cardiovascular effects
Allancer DC Nunes, Laylla S Ramalho, Álvaro PS Souza, Elizabeth P Mendes, Diego B Colugnati, Nícholas Zufelato, Marcelo H Sousa, Andris F Bakuzis & Carlos H Castro
Pages: 3299-3312
Published online: 08 Jul 2014
AbstractforManganese ferrite-based nanoparticles induce ex vivo, but not in vivo, cardiovascular effects | Full Text | References | PDF (2.7 MB)
  • 69 Views
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Article
Nanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid
Jing Yao, Yuanke Li, Xiaojing Sun, Fatima Zohra Dahmani, Hongpan Liu & Jianping Zhou
Pages: 3313-3324
Published online: 10 Jul 2014
AbstractforNanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid | Full Text | References | PDF (5.3 MB)
  • 69 Views
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Article
Understanding improved osteoblast behavior on select nanoporous anodic alumina
Siyu Ni, Changyan Li, Shirong Ni, Ting Chen & Thomas J Webster
Pages: 3325-3334
Published online: 10 Jul 2014
AbstractforUnderstanding improved osteoblast behavior on select nanoporous anodic alumina | Full Text | References | PDF (3.6 MB)
  • 51 Views
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Article
Enhanced photodynamic leishmanicidal activity of hydrophobic zinc phthalocyanine within archaeolipids containing liposomes
Ana Paula Perez, Agustina Casasco, Priscila Schilrreff, Maria Victoria Defain Tesoriero, Luc Duempelmann, Maria Julia Altube, Leticia Higa, Maria Jose Morilla, Patricia Petray & Eder L Romero
Pages: 3335-3345
Published online: 10 Jul 2014
AbstractforEnhanced photodynamic leishmanicidal activity of hydrophobic zinc phthalocyanine within archaeolipids containing liposomes | Full Text | References | PDF (971.5 KB)
  • 70 Views
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Article
Theranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging
Dan Li, Xin Tang, Benjamin Pulli, Chao Lin, Peng Zhao, Jian Cheng, Zhongwei Lv, Xueyu Yuan, Qiong Luo, Haidong Cai & Meng Ye
Pages: 3347-3361
Published online: 10 Jul 2014
AbstractforTheranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging | Full Text | References | PDF (4.5 MB)
  • 89 Views
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Article
Comparative study of bioactivity of collagen scaffolds coated with graphene oxide and reduced graphene oxide
Izumi Kanayama, Hirofumi Miyaji, Hiroko Takita, Erika Nishida, Maiko Tsuji, Bunshi Fugetsu, Ling Sun, Kana Inoue, Asako Ibara, Tsukasa Akasaka, Tsutomu Sugaya & Masamitsu Kawanami
Pages: 3363-3373
Published online: 11 Jul 2014
AbstractforComparative study of bioactivity of collagen scaffolds coated with graphene oxide and reduced graphene oxide | Full Text | References | PDF (4.7 MB)
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Letter

Letter
Challenging nanoparticles: a target of personalized adhesion prevention strategy
Ospan A Mynbaev, Marina Yu Eliseeva, Antonio Malvasi & Andrea Tinelli
Pages: 3375-3376
Published online: 15 Jul 2014
CitationforChallenging nanoparticles: a target of personalized adhesion prevention strategy | Full Text | References | PDF (118.5 KB)
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Original Research

Article
Cationic star-shaped polymer as an siRNA carrier for reducing MMP-9 expression in skin fibroblast cells and promoting wound healing in diabetic rats
Na Li, Heng-Cong Luo, Chuan Yang, Jun-Jie Deng, Meng Ren, Xiao-Ying Xie, Diao-Zhu Lin, Li Yan & Li-Ming Zhang
Pages: 3377-3387
Published online: 15 Jul 2014
AbstractforCationic star-shaped polymer as an siRNA carrier for reducing MMP-9 expression in skin fibroblast cells and promoting wound healing in diabetic rats | Full Text | References | PDF (4.1 MB)
  • 115 Views
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Article
Existence, release, and antibacterial actions of silver nanoparticles on Ag–PIII TiO2 films with different nanotopographies
Jinhua Li, Yuqin Qiao, Hongqin Zhu, Fanhao Meng & Xuanyong Liu
Pages: 3389-3402
Published online: 16 Jul 2014
AbstractforExistence, release, and antibacterial actions of silver nanoparticles on Ag–PIII TiO2 films with different nanotopographies | Full Text | References | PDF (11.6 MB)
  • 55 Views
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Article
Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways
Jiezhong Chen, Renfu Shao, Li Li, Zhi Ping Xu & Wenyi Gu
Pages: 3403-3411
Published online: 16 Jul 2014
AbstractforEffective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways | Full Text | References | PDF (1.8 MB)
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Article
Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions
Deqing Sun, Xinbing Wei, Xia Xue, Zengjun Fang, Manru Ren, Haiyan Lou & Xiumei Zhang
Pages: 3413-3423
Published online: 18 Jul 2014
AbstractforEnhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions | Full Text | References | PDF (4.8 MB)
  • 116 Views
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Article
The co-delivery of a low-dose P-glycoprotein inhibitor with doxorubicin sterically stabilized liposomes against breast cancer with low P-glycoprotein expression
Wei Gao, Zhiqiang Lin, Meiwan Chen, Xiucong Yang, Zheng Cui, Xiaofei Zhang, Lan Yuan & Qiang Zhang
Pages: 3425-3437
Published online: 27 Feb 2023
AbstractforThe co-delivery of a low-dose P-glycoprotein inhibitor with doxorubicin sterically stabilized liposomes against breast cancer with low P-glycoprotein expression | Full Text | References | PDF (2.1 MB)
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Article
Pluronic® L64-mediated stable HIF-1α expression in muscle for therapeutic angiogenesis in mouse hindlimb ischemia
Hongmei Song, Sijia Liu, Caixia Li, Yanyan Geng, Gang Wang & Zhongwei Gu
Pages: 3439-3452
Published online: 21 Jul 2014
AbstractforPluronic® L64-mediated stable HIF-1α expression in muscle for therapeutic angiogenesis in mouse hindlimb ischemia | Full Text | References | PDF (3.3 MB)
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Article
Preparation and evaluation of microemulsion-based transdermal delivery of total flavone of rhizoma arisaematis
Li-Na Shen, Yong-Tai Zhang, Qin Wang, Ling Xu & Nian-Ping Feng
Pages: 3453-3464
Published online: 22 Jul 2014
AbstractforPreparation and evaluation of microemulsion-based transdermal delivery of total flavone of rhizoma arisaematis | Full Text | References | PDF (4.6 MB)
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Review

Review Article
Nanopharmacology in translational hematology and oncology
Ciprian Tomuleasa, Cornelia Braicu, Alexandra Irimie, Lucian Craciun & Ioana Berindan-Neagoe
Pages: 3465-3479
Published online: 22 Jul 2014
AbstractforNanopharmacology in translational hematology and oncology | Full Text | References | PDF (2.5 MB)
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Original Research

Article
Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles
Catherine A Schütz, Davide Staedler, Kieran Crosbie-Staunton, Dania Movia, Catherine Chapuis Bernasconi, Blanka Halamoda Kenzaoui, Adriele Prina-Mello & Lucienne Juillerat-Jeanneret
Pages: 3481-3498
Published online: 23 Jul 2014
AbstractforDifferential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles | Full Text | References | PDF (6 MB)
  • 72 Views
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Article
Ultrastructural localization of intravenously injected carbon nanohorns in tumor
Sachiko Matsumura, Ryota Yuge, Shigeo Sato, Akihiro Tomida, Toshinari Ichihashi, Hiroshi Irie, Sumio Iijima, Kiyotaka Shiba & Masako Yudasaka
Pages: 3499-3508
Published online: 23 Jul 2014
AbstractforUltrastructural localization of intravenously injected carbon nanohorns in tumor | Full Text | References | PDF (5.6 MB)
  • 46 Views
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Article
Self-assembled nanoparticles based on the c(RGDfk) peptide for the delivery of siRNA targeting the VEGFR2 gene for tumor therapy
Li Liu, Xiaoxia Liu, Qian Xu, Ping Wu, Xialin Zuo, Jingjing Zhang, Houliang Deng, Zhuomin Wu & Aimin Ji
Pages: 3509-3526
Published online: 29 Jul 2014
AbstractforSelf-assembled nanoparticles based on the c(RGDfk) peptide for the delivery of siRNA targeting the VEGFR2 gene for tumor therapy | Full Text | References | PDF (7.1 MB)
  • 69 Views
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Review

Review Article
Developments in human growth hormone preparations: sustained-release, prolonged half-life, novel injection devices, and alternative delivery routes
Yunpeng Cai, Mingxin Xu, Minglu Yuan, Zhenguo Liu & Weien Yuan
Pages: 3527-3538
Published online: 25 Jul 2014
AbstractforDevelopments in human growth hormone preparations: sustained-release, prolonged half-life, novel injection devices, and alternative delivery routes | Full Text | References | PDF (1.4 MB)
  • 213 Views
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Original Research

Article
Investigation of the mechanism of enhanced skin penetration by ultradeformable liposomes
Thirapit Subongkot, Boonnada Pamornpathomkul, Theerasak Rojanarata, Praneet Opanasopit & Tanasait Ngawhirunpat
Pages: 3539-3550
Published online: 25 Jul 2014
AbstractforInvestigation of the mechanism of enhanced skin penetration by ultradeformable liposomes | Full Text | References | PDF (11.8 MB)
  • 112 Views
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Article
Antibacterial properties of silver nanoparticles synthesized using Pulicaria glutinosa plant extract as a green bioreductant
Mujeeb Khan, Shams Tabrez Khan, Merajuddin Khan, Syed Farooq Adil, Javed Musarrat, Abdulaziz A Al-Khedhairy, Abdulrahman Al-Warthan, Mohammed Rafiq H Siddiqui & Hamad Z Alkhathlan
Pages: 3551-3565
Published online: 28 Jul 2014
AbstractforAntibacterial properties of silver nanoparticles synthesized using Pulicaria glutinosa plant extract as a green bioreductant | Full Text | References | PDF (9 MB)
  • 130 Views
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Article
High gene delivery efficiency of alkylated low-molecular-weight polyethylenimine through gemini surfactant-like effect
Shan Liu, Wei Huang, Ming-Ji Jin, Qi-Ming Wang, Gan-Lin Zhang, Xiao-Min Wang, Shuai Shao & Zhong-Gao Gao
Pages: 3567-3581
Published online: 28 Jul 2014
AbstractforHigh gene delivery efficiency of alkylated low-molecular-weight polyethylenimine through gemini surfactant-like effect | Full Text | References | PDF (4.9 MB)
  • 40 Views
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Article
Hemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy
Tanja Schaffran, Nan Jiang, Markus Bergmann, Ekkehard Küstermann, Regine Süss, Rolf Schubert, Franz M Wagner, Doaa Awad & Detlef Gabel
Pages: 3583-3590
Published online: 29 Jul 2014
AbstractforHemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy | Full Text | References | PDF (2.8 MB)
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Article
Enhanced activity of carbosilane dendrimers against HIV when combined with reverse transcriptase inhibitor drugs: searching for more potent microbicides
Enrique Vacas-Córdoba, Marta Galán, Francisco J de la Mata, Rafael Gómez, Marjorie Pion & M Ángeles Muñoz-Fernández
Pages: 3591-3600
Published online: 29 Jul 2014
AbstractforEnhanced activity of carbosilane dendrimers against HIV when combined with reverse transcriptase inhibitor drugs: searching for more potent microbicides | Full Text | References | PDF (2.8 MB)
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Article
2′-(2-bromohexadecanoyl)-paclitaxel conjugate nanoparticles for the treatment of non-small cell lung cancer in an orthotopic xenograft mouse model
Lei Peng, Allison N Schorzman, Ping Ma, Andrew J Madden, William C Zamboni, Soumya Rahima Benhabbour & Russell J Mumper
Pages: 3601-3610
Published online: 30 Jul 2014
Abstractfor2′-(2-bromohexadecanoyl)-paclitaxel conjugate nanoparticles for the treatment of non-small cell lung cancer in an orthotopic xenograft mouse model | Full Text | References | PDF (1.8 MB)
  • 69 Views
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Article
The application of EDTA in drug delivery systems: doxorubicin liposomes loaded via NH4EDTA gradient
Yanzhi Song, Zhenjun Huang, Yang Song, Qingjing Tian, Xinrong Liu, Zhennan She, Jiao Jiao, Eliza Lu & Yihui Deng
Pages: 3611-3621
Published online: 01 Aug 2014
AbstractforThe application of EDTA in drug delivery systems: doxorubicin liposomes loaded via NH4EDTA gradient | Full Text | References | PDF (2.7 MB)
  • 119 Views
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Article
Preparation, pharmacokinetics and biodistribution of baicalin-loaded liposomes
Yumeng Wei, Jianmin Guo, Xiaoli Zheng, Jun Wu, Yang Zhou, Yu Yu, Yun Ye, Liangke Zhang & Ling Zhao
Pages: 3623-3630
Published online: 01 Aug 2014
AbstractforPreparation, pharmacokinetics and biodistribution of baicalin-loaded liposomes | Full Text | References | PDF (537.3 KB)
  • 179 Views
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Article
Effects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses
Chih-Hong Pan, Wen-Te Liu, Mauo-Ying Bien, I-Chan Lin, Ta-Chih Hsiao, Chih-Ming Ma, Ching-Huang Lai, Mei-Chieh Chen, Kai-Jen Chuang, Hsiao-Chi Chuang & On behalf of the Taiwan CardioPulmonary Research (T-CPR) Group
Pages: 3631-3643
Published online: 02 Aug 2014
AbstractforEffects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses | Full Text | References | PDF (3.5 MB)
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Article
Tolerance-like innate immunity and spleen injury: a novel discovery via the weekly administrations and consecutive injections of PEGylated emulsions
Long Wang, Chunling Wang, Jiao Jiao, Yuqing Su, Xiaobo Cheng, Zhenjun Huang, Xinrong Liu & Yihui Deng
Pages: 3645-3657
Published online: 04 Aug 2014
AbstractforTolerance-like innate immunity and spleen injury: a novel discovery via the weekly administrations and consecutive injections of PEGylated emulsions | Full Text | References | PDF (4.9 MB)
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Article
Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery
Harald Unterweger, Rainer Tietze, Christina Janko, Jan Zaloga, Stefan Lyer, Stephan Dürr, Nicola Taccardi, Ourania-Menti Goudouri, Alexander Hoppe, Dietmar Eberbeck, Dirk W Schubert, Aldo R Boccaccini & Christoph Alexiou
Pages: 3659-3676
Published online: 05 Aug 2014
AbstractforDevelopment and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery | Full Text | References | PDF (10.7 MB)
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Article
Cellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles
Porntip Pan-In, Supason Wanichwecharungruang, Justin Hanes & Anthony J Kim
Pages: 3677-3686
Published online: 06 Aug 2014
AbstractforCellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles | Full Text | References | PDF (1.7 MB)
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Article
Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites
Elena Filová, Tomáš Suchý, Zbyněk Sucharda, Monika Šupová, Margit Žaloudková, Karel Balík, Věra Lisá, Miroslav Šlouf & Lucie Bačáková
Pages: 3687-3706
Published online: 06 Aug 2014
AbstractforSupport for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites | Full Text | References | PDF (10.3 MB)
  • 86 Views
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Article
Role of surface modification in zinc oxide nanoparticles and its toxicity assessment toward human dermal fibroblast cells
Mohankandhasamy Ramasamy, Minakshi Das, Seong Soo A An & Dong Kee Yi
Pages: 3707-3718
Published online: 07 Aug 2014
AbstractforRole of surface modification in zinc oxide nanoparticles and its toxicity assessment toward human dermal fibroblast cells | Full Text | References | PDF (7 MB)
  • 209 Views
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Review

Review Article
Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
Giovana Calixto, Jéssica Bernegossi, Bruno Fonseca-Santos & Marlus Chorilli
Pages: 3719-3735
Published online: 08 Aug 2014
AbstractforNanotechnology-based drug delivery systems for treatment of oral cancer: a review | Full Text | References | PDF (924.2 KB)
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Original Research

Article
Biophysical evaluation of cells on nanotubular surfaces: the effects of atomic ordering and chemistry
Tolou Shokuhfar, Azhang Hamlekhan, Jen-Yung Chang, Chang Kyoung Choi, Cortino Sukotjo & Craig Friedrich
Pages: 3737-3748
Published online: 12 Aug 2014
AbstractforBiophysical evaluation of cells on nanotubular surfaces: the effects of atomic ordering and chemistry | Full Text | References | PDF (10.4 MB)
  • 55 Views
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Review

Review Article
Therapeutics with SPION-labeled stem cells for the main diseases related to brain aging: a systematic review
Larissa T Alvarim, Leopoldo P Nucci, Javier B Mamani, Luciana C Marti, Marina F Aguiar, Helio R Silva, Gisele S Silva, Mariana P Nucci-da-Silva, Elaine A DelBel & Lionel F Gamarra
Pages: 3749-3770
Published online: 11 Aug 2014
AbstractforTherapeutics with SPION-labeled stem cells for the main diseases related to brain aging: a systematic review | Full Text | References | PDF (2.8 MB)
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Original Research

Article
Extraction of human genomic DNA from whole blood using a magnetic microsphere method
Rui Gong & Shengying Li
Pages: 3781-3789
Published online: 08 Aug 2014
AbstractforExtraction of human genomic DNA from whole blood using a magnetic microsphere method | Full Text | References | PDF (1.5 MB)
  • 259 Views
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Article
Supercritical fluid-mediated liposomes containing cyclosporin A for the treatment of dry eye syndrome in a rabbit model: comparative study with the conventional cyclosporin A emulsion
Pankaj Ranjan Karn, Hyun Do Kim, Han Kang, Bo Kyung Sun, Su-Eon Jin & Sung-Joo Hwang
Pages: 3791-3800
Published online: 08 Aug 2014
AbstractforSupercritical fluid-mediated liposomes containing cyclosporin A for the treatment of dry eye syndrome in a rabbit model: comparative study with the conventional cyclosporin A emulsion | Full Text | References | PDF (1.5 MB)
  • 143 Views
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Article
Synthesis, characterization, and antimicrobial activity of an ampicillin-conjugated magnetic nanoantibiotic for medical applications
Samer Hasan Hussein-Al-Ali, Mohamed Ezzat El Zowalaty, Mohd Zobir Hussein, Benjamin M Geilich & Thomas J Webster
Pages: 3801-3814
Published online: 08 Aug 2014
AbstractforSynthesis, characterization, and antimicrobial activity of an ampicillin-conjugated magnetic nanoantibiotic for medical applications | Full Text | References | PDF (2.9 MB)
  • 361 Views
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Article
The influence of bile salt on the chemotherapeutic response of docetaxel-loaded thermosensitive nanomicelles
Dong Wuk Kim, Thiruganesh Ramasamy, Ju Yeon Choi, Jeong Hwan Kim, Chul Soon Yong, Jong Oh Kim & Han-Gon Choi
Pages: 3815-3824
Published online: 08 Aug 2014
AbstractforThe influence of bile salt on the chemotherapeutic response of docetaxel-loaded thermosensitive nanomicelles | Full Text | References | PDF (1.8 MB)
  • 63 Views
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Article
EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage
Shinji Kuroda, Justina Tam, Jack A Roth, Konstantin Sokolov & Rajagopal Ramesh
Pages: 3825-3839
Published online: 08 Aug 2014
AbstractforEGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage | Full Text | References | PDF (4.3 MB)
  • 60 Views
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Article
The therapeutic effects of MSc1 nanocomplex, synthesized by nanochelating technology, on experimental autoimmune encephalomyelitic C57/BL6 mice
Saideh Fakharzadeh, Mohammad Ali Sahraian, Maryam Hafizi, Somayeh Kalanaky, Zahra Masoumi, Mehdi Mahdavi, Nasser Kamalian, Alireza Minagar & Mohammad Hassan Nazaran
Pages: 3841-3853
Published online: 11 Aug 2014
AbstractforThe therapeutic effects of MSc1 nanocomplex, synthesized by nanochelating technology, on experimental autoimmune encephalomyelitic C57/BL6 mice | Full Text | References | PDF (5.5 MB)
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Article
Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration
Deise Michele Tichota, Ana Catarina Silva, José Manuel Sousa Lobo & Maria Helena Amaral
Pages: 3855-3864
Published online: 11 Aug 2014
AbstractforDesign, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration | Full Text | References | PDF (1.7 MB)
  • 442 Views
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Article
Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles
Wesley Nyaigoti Omwoyo, Bernhards Ogutu, Florence Oloo, Hulda Swai, Lonji Kalombo, Paula Melariri, Geoffrey Maroa Mahanga & Jeremiah Waweru Gathirwa
Pages: 3865-3874
Published online: 11 Aug 2014
AbstractforPreparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles | Full Text | References | PDF (1.2 MB)
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Article
Development of nanofluorapatite polymer-based composite for bioactive orthopedic implants and prostheses
Gangfeng Hu, Hui Wang, Xiaocong Yao, Dawei Bi, Gang Zhu, Songchao Tang, Jie Wei, Lili Yang, Peijian Tong & Luwei Xiao
Pages: 3875-3884
Published online: 11 Aug 2014
AbstractforDevelopment of nanofluorapatite polymer-based composite for bioactive orthopedic implants and prostheses | Full Text | References | PDF (5.9 MB)
  • 60 Views
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Article
Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation
Emilie Seydoux, Barbara Rothen-Rutishauser, Izabela M Nita, Sandor Balog, Amiq Gazdhar, Philip A Stumbles, Alke Petri-Fink, Fabian Blank & Christophe von Garnier
Pages: 3885-3902
Published online: 13 Aug 2014
AbstractforSize-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation | Full Text | References | PDF (5.6 MB)
  • 66 Views
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Article
Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
Pär Johansson, Ryo Jimbo, Per Kjellin, Fredrik Currie, Bruno Ramos Chrcanovic & Ann Wennerberg
Pages: 3903-3911
Published online: 14 Aug 2014
AbstractforBiomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia | Full Text | References | PDF (3.7 MB)
  • 186 Views
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Article
Toxicity of pristine graphene in experiments in a chicken embryo model
Ewa Sawosz, Slawomir Jaworski, Marta Kutwin, Anna Hotowy, Mateusz Wierzbicki, Marta Grodzik, Natalia Kurantowicz, Barbara Strojny, Ludwika Lipińska & André Chwalibog
Pages: 3913-3922
Published online: 14 Aug 2014
AbstractforToxicity of pristine graphene in experiments in a chicken embryo model | Full Text | References | PDF (6.5 MB)
  • 192 Views
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Article
Enhanced brain delivery of lamotrigine with Pluronic® P123-based nanocarrier
Jian-Sheng Liu, Jian-Hong Wang, Jie Zhou, Xing-Hua Tang, Lan Xu, Teng Shen, Xun-Yi Wu & Zhen Hong
Pages: 3923-3935
Published online: 16 Aug 2014
AbstractforEnhanced brain delivery of lamotrigine with Pluronic® P123-based nanocarrier | Full Text | References | PDF (4.6 MB)
  • 125 Views
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Article
Facile and green fabrication of electrospun poly(vinyl alcohol) nanofibrous mats doped with narrowly dispersed silver nanoparticles
Song Lin, Run-Ze Wang, Ying Yi, Zheng Wang, Li-Mei Hao, Jin-Hui Wu, Guo-Han Hu & Hua He
Pages: 3937-3947
Published online: 18 Aug 2014
AbstractforFacile and green fabrication of electrospun poly(vinyl alcohol) nanofibrous mats doped with narrowly dispersed silver nanoparticles | Full Text | References | PDF (4.1 MB)
  • 80 Views
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Article
Preparation, characterization, and in vitro osteoblast functions of a nano-hydroxyapatite/polyetheretherketone biocomposite as orthopedic implant material
Rui Ma, Songchao Tang, Honglue Tan, Wentao Lin, Yugang Wang, Jie Wei, Liming Zhao & Tingting Tang
Pages: 3949-3961
Published online: 18 Aug 2014
AbstractforPreparation, characterization, and in vitro osteoblast functions of a nano-hydroxyapatite/polyetheretherketone biocomposite as orthopedic implant material | Full Text | References | PDF (5.1 MB)
  • 100 Views
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Article
Local delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs
Wenxin Yao, Peicheng Xu, Zhiqing Pang, Jingjing Zhao, Zhilan Chai, Xiaoxia Li, Huan Li, Menglin Jiang, Hongbo Cheng, Bo Zhang & Nengneng Cheng
Pages: 3963-3970
Published online: 18 Aug 2014
AbstractforLocal delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs | Full Text | References | PDF (2 MB)
  • 172 Views
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Article
Sulfatide-containing lipid perfluorooctylbromide nanoparticles as paclitaxel vehicles targeting breast carcinoma
Xiao Li, Fei Qin, Li Yang, Liqian Mo, Lei Li & Lianbing Hou
Pages: 3971-3985
Published online: 18 Aug 2014
AbstractforSulfatide-containing lipid perfluorooctylbromide nanoparticles as paclitaxel vehicles targeting breast carcinoma | Full Text | References | PDF (7.7 MB)
  • 63 Views
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Article
Intracellular uptake of etoposide-loaded solid lipid nanoparticles induces an enhancing inhibitory effect on gastric cancer through mitochondria-mediated apoptosis pathway
Jiao Wang, Rongrong Zhu, Xiaoyu Sun, Yanjing Zhu, Hui Liu & Shi-Long Wang
Pages: 3987-3998
Published online: 20 Aug 2014
AbstractforIntracellular uptake of etoposide-loaded solid lipid nanoparticles induces an enhancing inhibitory effect on gastric cancer through mitochondria-mediated apoptosis pathway | Full Text | References | PDF (5.3 MB)
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Review

Review Article
Toxicology of antimicrobial nanoparticles for prosthetic devices
Rosa Elvira Nuñez-Anita, Laura Susana Acosta-Torres, Jorge Vilar-Pineda, Juan Carlos Martínez-Espinosa, Javier de la Fuente-Hernández & Víctor Manuel Castaño
Pages: 3999-4006
Published online: 20 Aug 2014
AbstractforToxicology of antimicrobial nanoparticles for prosthetic devices | Full Text | References | PDF (266 KB)
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Original Research

Article
Green synthesis of gold nanoparticles using plant extracts as reducing agents
Paz Elia, Raya Zach, Sharon Hazan, Sofiya Kolusheva, Ze’ev Porat & Yehuda Zeiri
Pages: 4007-4021
Published online: 20 Aug 2014
AbstractforGreen synthesis of gold nanoparticles using plant extracts as reducing agents | Full Text | References | PDF (4.9 MB)
  • 2146 Views
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Article
Antioxidative fullerol promotes osteogenesis of human adipose-derived stem cells
Xinlin Yang, Ching-Ju Li, Yueping Wan, Pinar Smith, Guowei Shang & Quanjun Cui
Pages: 4023-4031
Published online: 20 Aug 2014
AbstractforAntioxidative fullerol promotes osteogenesis of human adipose-derived stem cells | Full Text | References | PDF (1.5 MB)
  • 56 Views
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Corrigendum

Correction
Fabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity [Corrigendum]
Page: 4033
Published online: 21 Aug 2014
CitationforFabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity [Corrigendum] | Full Text | PDF (98.7 KB)
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Original Research

Article
Preparation of bufalin-loaded pluronic polyetherimide nanoparticles, cellular uptake, distribution, and effect on colorectal cancer
Qiang Hu, Bo Liang, Ying Sun, Xiao-Ling Guo, Yi-Jie Bao, Dong-Hao Xie, Ming Zhou, You-Rong Duan, Pei-Hao Yin & Zhi-Hai Peng
Pages: 4035-4041
Published online: 21 Aug 2014
AbstractforPreparation of bufalin-loaded pluronic polyetherimide nanoparticles, cellular uptake, distribution, and effect on colorectal cancer | Full Text | References | PDF (3.2 MB)
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Article
Toxicity evaluation of Gd2O3@SiO2 nanoparticles prepared by laser ablation in liquid as MRI contrast agents in vivo
Xiumei Tian, Fanwen Yang, Chuan Yang, Ye Peng, Dihu Chen, Jixiang Zhu, Fupo He, Li Li & Xiaoming Chen
Pages: 4043-4053
Published online: 21 Aug 2014
AbstractforToxicity evaluation of Gd2O3@SiO2 nanoparticles prepared by laser ablation in liquid as MRI contrast agents in vivo | Full Text | References | PDF (4.2 MB)
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Article
Design of multifunctional magnetic iron oxide nanoparticles/mitoxantrone-loaded liposomes for both magnetic resonance imaging and targeted cancer therapy
Yingna He, Linhua Zhang, Dunwan Zhu & Cunxian Song
Pages: 4055-4066
Published online: 22 Aug 2014
AbstractforDesign of multifunctional magnetic iron oxide nanoparticles/mitoxantrone-loaded liposomes for both magnetic resonance imaging and targeted cancer therapy | Full Text | References | PDF (2.6 MB)
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Article
PLGA nanofiber membranes loaded with epigallocatechin-3-O-gallate are beneficial to prevention of postsurgical adhesions
Yong Cheol Shin, Won Jun Yang, Jong Ho Lee, Jin-Woo Oh, Tai Wan Kim, Jong-Chul Park, Suong-Hyu Hyon & Dong-Wook Han
Pages: 4067-4078
Published online: 22 Aug 2014
AbstractforPLGA nanofiber membranes loaded with epigallocatechin-3-O-gallate are beneficial to prevention of postsurgical adhesions | Full Text | References | PDF (4.7 MB)
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Article
Preparation and characterization of antiadhesion barrier film from hyaluronic acid-grafted electrospun poly(caprolactone) nanofibrous membranes for prevention of flexor tendon postoperative peritendinous adhesion
Shih-Hsien Chen, Chih-Hao Chen, K T Shalumon & Jyh-Ping Chen
Pages: 4079-4092
Published online: 22 Aug 2014
AbstractforPreparation and characterization of antiadhesion barrier film from hyaluronic acid-grafted electrospun poly(caprolactone) nanofibrous membranes for prevention of flexor tendon postoperative peritendinous adhesion | Full Text | References | PDF (5.4 MB)
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Article
Multiwalled carbon nanotubes induce altered morphology and loss of barrier function in human bronchial epithelium at noncytotoxic doses
Ryan J Snyder, Salik Hussain, Annette B Rice & Stavros Garantziotis
Pages: 4093-4105
Published online: 25 Aug 2014
AbstractforMultiwalled carbon nanotubes induce altered morphology and loss of barrier function in human bronchial epithelium at noncytotoxic doses | Full Text | References | PDF (9.1 MB)
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Article
Transferrin-modified nanostructured lipid carriers as multifunctional nanomedicine for codelivery of DNA and doxorubicin
Yiqun Han, Ying Zhang, Danni Li, Yuanyuan Chen, Jiping Sun & Fansheng Kong
Pages: 4107-4116
Published online: 25 Aug 2014
AbstractforTransferrin-modified nanostructured lipid carriers as multifunctional nanomedicine for codelivery of DNA and doxorubicin | Full Text | References | PDF (1.5 MB)
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Article
Promoting endothelial recovery and reducing neointimal hyperplasia using sequential-like release of acetylsalicylic acid and paclitaxel-loaded biodegradable stents
Cheng-Hung Lee, Chia-Ying Yu, Shang-Hung Chang, Kuo-Chun Hung, Shih-Jung Liu, Chao-Jan Wang, Ming-Yi Hsu, I-Chang Hsieh, Wei-Jan Chen, Yu-Shien Ko & Ming-Shien Wen
Pages: 4117-4133
Published online: 27 Aug 2014
AbstractforPromoting endothelial recovery and reducing neointimal hyperplasia using sequential-like release of acetylsalicylic acid and paclitaxel-loaded biodegradable stents | Full Text | References | PDF (6.5 MB)
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Article
Electrospun fibrous scaffolds combined with nanoscale hydroxyapatite induce osteogenic differentiation of human periodontal ligament cells
Xiaonan Wu, Leiying Miao, Yingfang Yao, Wenlei Wu, Yu Liu, Xiaofeng Chen & Weibin Sun
Pages: 4135-4143
Published online: 27 Aug 2014
AbstractforElectrospun fibrous scaffolds combined with nanoscale hydroxyapatite induce osteogenic differentiation of human periodontal ligament cells | Full Text | References | PDF (4 MB)
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Article
Functionalization of ethylene vinyl acetate with antimicrobial chlorhexidine hexametaphosphate nanoparticles
Natalie J Wood, Sarah E Maddocks, Helena J Grady, Andrew M Collins & Michele E Barbour
Pages: 4145-4152
Published online: 27 Aug 2014
AbstractforFunctionalization of ethylene vinyl acetate with antimicrobial chlorhexidine hexametaphosphate nanoparticles | Full Text | References | PDF (7.8 MB)
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Review

Review Article
Regenerative nanomedicine: current perspectives and future directions
Koel Chaudhury, Vishu Kumar, Jayaprakash Kandasamy & Sourav RoyChoudhury
Pages: 4153-4167
Published online: 01 Sep 2014
AbstractforRegenerative nanomedicine: current perspectives and future directions | Full Text | References | PDF (1.8 MB)
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Original Research

Article
Assessment and optimization of electroporation-assisted tumoral nanoparticle uptake in a nude mouse model of pancreatic ductal adenocarcinoma
Derek Lamont West, Sarah B White, Zhouli Zhang, Andrew C Larson & Reed A Omary
Pages: 4169-4176
Published online: 01 Sep 2014
AbstractforAssessment and optimization of electroporation-assisted tumoral nanoparticle uptake in a nude mouse model of pancreatic ductal adenocarcinoma | Full Text | References | PDF (2.2 MB)
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Article
Effect of hydroxyapatite-containing microspheres embedded into three-dimensional magnesium phosphate scaffolds on the controlled release of lysozyme and in vitro biodegradation
Jongman Lee & Hui-suk Yun
Pages: 4177-4189
Published online: 01 Sep 2014
AbstractforEffect of hydroxyapatite-containing microspheres embedded into three-dimensional magnesium phosphate scaffolds on the controlled release of lysozyme and in vitro biodegradation | Full Text | References | PDF (4.6 MB)
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Article
Preparation and therapeutic evaluation of 188Re-thermogelling emulsion in rat model of hepatocellular carcinoma
Ying-Hsia Shih, Xi-Zhang Lin, Chung-Hsin Yeh, Cheng-Liang Peng, Ming-Jium Shieh, Wuu-Jyh Lin & Tsai-Yueh Luo
Pages: 4191-4201
Published online: 02 Sep 2014
AbstractforPreparation and therapeutic evaluation of 188Re-thermogelling emulsion in rat model of hepatocellular carcinoma | Full Text | References | PDF (3.2 MB)
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Article
Magnetic particle imaging: kinetics of the intravascular signal in vivo
Julian Haegele, Robert L Duschka, Matthias Graeser, Catharina Schaecke, Nikolaos Panagiotopoulos, Kerstin Lüdtke-Buzug, Thorsten M Buzug, Jörg Barkhausen & Florian M Vogt
Pages: 4203-4209
Published online: 03 Sep 2014
AbstractforMagnetic particle imaging: kinetics of the intravascular signal in vivo | Full Text | References | PDF (364.9 KB)
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Article
Interleukin 10-coated nanoparticle systems compared for molecular imaging of atherosclerotic lesions
Gunter Almer, Kelli L Summers, Bernhard Scheicher, Josef Kellner, Ingeborg Stelzer, Gerd Leitinger, Anna Gries, Ruth Prassl, Andreas Zimmer & Harald Mangge
Pages: 4211-4222
Published online: 03 Sep 2014
AbstractforInterleukin 10-coated nanoparticle systems compared for molecular imaging of atherosclerotic lesions | Full Text | References | PDF (11 MB)
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Article
In vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery
Anna B Banizs, Tao Huang, Kelly Dryden, Stuart S Berr, James R Stone, Robert K Nakamoto, Weibin Shi & Jiang He
Pages: 4223-4230
Published online: 03 Sep 2014
AbstractforIn vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery | Full Text | References | PDF (1.8 MB)
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Article
Preparation of folic acid-conjugated, doxorubicin-loaded, magnetic bovine serum albumin nanospheres and their antitumor effects in vitro and in vivo
Rui Yang, YanLi An, FengQin Miao, MengFei Li, PeiDang Liu & QiuSha Tang
Pages: 4231-4243
Published online: 04 Sep 2014
AbstractforPreparation of folic acid-conjugated, doxorubicin-loaded, magnetic bovine serum albumin nanospheres and their antitumor effects in vitro and in vivo | Full Text | References | PDF (2.5 MB)
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Article
Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes
J Justin Mulvey, Evan N Feinberg, Simone Alidori, Michael R McDevitt, Daniel A Heller & David A Scheinberg
Pages: 4245-4255
Published online: 04 Sep 2014
AbstractforSynthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes | Full Text | References | PDF (1.6 MB)
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Article
Polyethylene glycol-coated graphene oxide attenuates antigen-specific IgE production and enhanced antigen-induced T-cell reactivity in ovalbumin-sensitized BALB/c mice
Hsin-Ying Wu, Kun-Ju Lin, Ping-Yen Wang, Chi-Wen Lin, Hong-Wei Yang, Chen-Chi M Ma, Yu-Jen Lu & Tong-Rong Jan
Pages: 4257-4266
Published online: 08 Sep 2014
AbstractforPolyethylene glycol-coated graphene oxide attenuates antigen-specific IgE production and enhanced antigen-induced T-cell reactivity in ovalbumin-sensitized BALB/c mice | Full Text | References | PDF (2.2 MB)
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Article
Application of apolipoprotein E-modified liposomal nanoparticles as a carrier for delivering DNA and nucleic acid in the brain
Mina Tamaru, Hidetaka Akita, Taichi Nakatani, Kazuaki Kajimoto, Yusuke Sato, Hiroto Hatakeyama & Hideyoshi Harashima
Pages: 4267-4276
Published online: 08 Sep 2014
AbstractforApplication of apolipoprotein E-modified liposomal nanoparticles as a carrier for delivering DNA and nucleic acid in the brain | Full Text | References | PDF (2.6 MB)
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Article
Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model
Antonio Barrientos-Durán, Ellen M Carpenter, Nicole I zur Nieden, Theodore I Malinin, Juan Carlos Rodríguez-Manzaneque & Laura P Zanello
Pages: 4277-4291
Published online: 09 Sep 2014
AbstractforCarboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model | Full Text | References | PDF (9.3 MB)
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Article
Improving effects of chitosan nanofiber scaffolds on osteoblast proliferation and maturation
Ming-Hua Ho, Mei-Hsiu Liao, Yi-Ling Lin, Chien-Hao Lai, Pei-I Lin & Ruei-Ming Chen
Pages: 4293-4304
Published online: 09 Sep 2014
AbstractforImproving effects of chitosan nanofiber scaffolds on osteoblast proliferation and maturation | Full Text | References | PDF (7 MB)
  • 144 Views
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Article
Nanostructured lipid carrier surface modified with Eudragit RS 100 and its potential ophthalmic functions
Wenji Zhang, Xuedong Li, Tiantian Ye, Fen Chen, Shihui Yu, Jianting Chen, Xinggang Yang, Na Yang, Jinsong Zhang, Jinlu Liu, Weisan Pan & Jun Kong
Pages: 4305-4315
Published online: 11 Sep 2014
AbstractforNanostructured lipid carrier surface modified with Eudragit RS 100 and its potential ophthalmic functions | Full Text | References | PDF (2.4 MB)
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Article
Overendocytosis of gold nanoparticles increases autophagy and apoptosis in hypoxic human renal proximal tubular cells
Fengan Ding, Yiping Li, Jing Liu, Lei Liu, Wenmin Yu, Zhi Wang, Haifeng Ni, Bicheng Liu & Pingsheng Chen
Pages: 4317-4330
Published online: 12 Sep 2014
AbstractforOverendocytosis of gold nanoparticles increases autophagy and apoptosis in hypoxic human renal proximal tubular cells | Full Text | References | PDF (5.5 MB)
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Article
Experimental design and optimization of raloxifene hydrochloride loaded nanotransfersomes for transdermal application
Syed Mahmood, Muhammad Taher & Uttam Kumar Mandal
Pages: 4331-4346
Published online: 12 Sep 2014
AbstractforExperimental design and optimization of raloxifene hydrochloride loaded nanotransfersomes for transdermal application | Full Text | References | PDF (7.2 MB)
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Article
Biodegradable drug-eluting nanofiber-enveloped implants for sustained release of high bactericidal concentrations of vancomycin and ceftazidime: in vitro and in vivo studies
Yung-Heng Hsu, Dave Wei-Chih Chen, Chun-Der Tai, Ying-Chao Chou, Shih-Jung Liu, Steve Wen-Neng Ueng & Err-Cheng Chan
Pages: 4347-4355
Published online: 12 Sep 2014
AbstractforBiodegradable drug-eluting nanofiber-enveloped implants for sustained release of high bactericidal concentrations of vancomycin and ceftazidime: in vitro and in vivo studies | Full Text | References | PDF (3.1 MB)
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Review

Review Article
Nanopharmaceuticals (part 1): products on the market
Volkmar Weissig, Tracy K Pettinger & Nicole Murdock
Pages: 4357-4373
Published online: 15 Sep 2014
AbstractforNanopharmaceuticals (part 1): products on the market | Full Text | References | PDF (347 KB)
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Original Research

Article
Comparison of process parameter optimization using different designs in nanoemulsion-based formulation for transdermal delivery of fullerene
Cheng Loong Ngan, Mahiran Basri, Fui Fang Lye, Hamid Reza Fard Masoumi, Minaketan Tripathy, Roghayeh Abedi Karjiban & Emilia Abdul-Malek
Pages: 4375-4386
Published online: 15 Sep 2014
AbstractforComparison of process parameter optimization using different designs in nanoemulsion-based formulation for transdermal delivery of fullerene | Full Text | References | PDF (2.6 MB)
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Review

Review Article
Thermosensitive liposomal drug delivery systems: state of the art review
Barbara Kneidl, Michael Peller, Gerhard Winter, Lars H Lindner & Martin Hossann
Pages: 4387-4398
Published online: 16 Sep 2014
AbstractforThermosensitive liposomal drug delivery systems: state of the art review | Full Text | References | PDF (3.9 MB)
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Article
Nanouric acid or nanocalcium phosphate as central nidus to induce calcium oxalate stone formation: a high-resolution transmission electron microscopy study on urinary nanocrystallites
Jie Gao, Jun-Fa Xue, Meng Xu, Bao-Song Gui, Feng-Xin Wang & Jian-Ming Ouyang
Pages: 4399-4409
Published online: 16 Sep 2014
AbstractforNanouric acid or nanocalcium phosphate as central nidus to induce calcium oxalate stone formation: a high-resolution transmission electron microscopy study on urinary nanocrystallites | Full Text | References | PDF (4.9 MB)
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Article
Improved absorption and in vivo kinetic characteristics of nanoemulsions containing evodiamine–phospholipid nanocomplex
Jiangbo Hu, Dilong Chen, Rong Jiang, Qunyou Tan, Biyue Zhu & Jingqing Zhang
Pages: 4411-4420
Published online: 17 Sep 2014
AbstractforImproved absorption and in vivo kinetic characteristics of nanoemulsions containing evodiamine–phospholipid nanocomplex | Full Text | References | PDF (1.7 MB)
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Review

Review Article
Nanotubular surface modification of metallic implants via electrochemical anodization technique
Lu-Ning Wang, Ming Jin, Yudong Zheng, Yueping Guan, Xin Lu & Jing-Li Luo
Pages: 4421-4435
Published online: 17 Sep 2014
AbstractforNanotubular surface modification of metallic implants via electrochemical anodization technique | Full Text | References | PDF (5.6 MB)
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Article
Quantification of transient increase of the blood–brain barrier permeability to macromolecules by optimized focused ultrasound combined with microbubbles
Lingyan Shi, Paolo Palacio-Mancheno, Joseph Badami, Da Wi Shin, Min Zeng, Luis Cardoso, Raymond Tu & Bingmei M Fu
Pages: 4437-4448
Published online: 18 Sep 2014
AbstractforQuantification of transient increase of the blood–brain barrier permeability to macromolecules by optimized focused ultrasound combined with microbubbles | Full Text | References | PDF (3.7 MB)
  • 74 Views
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Article
Nanocomplexes of an insulinotropic drug: optimization, microparticle formation, and antidiabetic activity in rats
Enas Elmowafy, Rihab Osman, Abdel Hameed El-Shamy & Gehanne AS Awad
Pages: 4449-4465
Published online: 18 Sep 2014
AbstractforNanocomplexes of an insulinotropic drug: optimization, microparticle formation, and antidiabetic activity in rats | Full Text | References | PDF (14.2 MB)
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Article
Antimicrobial nanocapsules: from new solvent-free process to in vitro efficiency
Julie Steelandt, Damien Salmon, Elodie Gilbert, Eyad Almouazen, François NR Renaud, Laurène Roussel, Marek Haftek & Fabrice Pirot
Pages: 4467-4474
Published online: 19 Sep 2014
AbstractforAntimicrobial nanocapsules: from new solvent-free process to in vitro efficiency | Full Text | References | PDF (2.3 MB)
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Article
Nanoencapsulation of the sasanquasaponin from Camellia oleifera, its photo responsiveness and neuroprotective effects
Yong Ye, Haiting Xing & Yue Li
Pages: 4475-4484
Published online: 19 Sep 2014
AbstractforNanoencapsulation of the sasanquasaponin from Camellia oleifera, its photo responsiveness and neuroprotective effects | Full Text | References | PDF (2.1 MB)
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Article
Short-time focused ultrasound hyperthermia enhances liposomal doxorubicin delivery and antitumor efficacy for brain metastasis of breast cancer
Sheng-Kai Wu, Chi-Feng Chiang, Yu-Hone Hsu, Tzu-Hung Lin, Houng-Chi Liou, Wen-Mei Fu & Win-Li Lin
Pages: 4485-4494
Published online: 19 Sep 2014
AbstractforShort-time focused ultrasound hyperthermia enhances liposomal doxorubicin delivery and antitumor efficacy for brain metastasis of breast cancer | Full Text | References | PDF (3 MB)
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Article
Oxygen supersaturated fluid using fine micro/nanobubbles
Noriaki Matsuki, Takuji Ishikawa, Shingo Ichiba, Naoki Shiba, Yoshihito Ujike & Takami Yamaguchi
Pages: 4495-4505
Published online: 23 Sep 2014
AbstractforOxygen supersaturated fluid using fine micro/nanobubbles | Full Text | References | PDF (1,011.4 KB)
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Article
Silk fibroin nanoparticles constitute a vector for controlled release of resveratrol in an experimental model of inflammatory bowel disease in rats
Antonio Abel Lozano-Pérez, Alba Rodriguez-Nogales, Víctor Ortiz-Cullera, Francesca Algieri, José Garrido-Mesa, Pedro Zorrilla, M Elena Rodriguez-Cabezas, Natividad Garrido-Mesa, M Pilar Utrilla, Laura De Matteis, Jesús Martínez de la Fuente, José Luis Cenis & Julio Gálvez
Pages: 4507-4520
Published online: 23 Sep 2014
AbstractforSilk fibroin nanoparticles constitute a vector for controlled release of resveratrol in an experimental model of inflammatory bowel disease in rats | Full Text | References | PDF (2.7 MB)
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Article
Use of electrical impedance spectroscopy to detect malignant and potentially malignant oral lesions
Craig Murdoch, Brian H Brown, Vanessa Hearnden, Paul M Speight, Katy D’Apice, Anne M Hegarty, John A Tidy, T Jamie Healey, Peter E Highfield & Martin H Thornhill
Pages: 4521-4532
Published online: 23 Sep 2014
AbstractforUse of electrical impedance spectroscopy to detect malignant and potentially malignant oral lesions | Full Text | References | PDF (1.9 MB)
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Article
Preclinical evaluation of recombinant human IFNα2b-containing magnetoliposomes for treating hepatocellular carcinoma
Hui Ye, Jiansong Tong, Jianzhang Wu, Xia Xu, Shenjie Wu, Botao Tan, Mengjing Shi, Jianguang Wang, Weibo Zhao, Heng Jiang & Sha Jin
Pages: 4533-4550
Published online: 25 Sep 2014
AbstractforPreclinical evaluation of recombinant human IFNα2b-containing magnetoliposomes for treating hepatocellular carcinoma | Full Text | References | PDF (2.7 MB)
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Article
Enhanced regenerative healing efficacy of a highly skin-permeable growth factor nanocomplex in a full-thickness excisional mouse wound model
Il-Hong Bae, Jin Woo Park & Dae-Yong Kim
Pages: 4551-4567
Published online: 25 Sep 2014
AbstractforEnhanced regenerative healing efficacy of a highly skin-permeable growth factor nanocomplex in a full-thickness excisional mouse wound model | Full Text | References | PDF (4.5 MB)
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Article
Enhancement of osseointegration of polyethylene terephthalate artificial ligament by coating of silk fibroin and depositing of hydroxyapatite
Jia Jiang, Fang Wan, Jianjun Yang, Wei Hao, Yaxian Wang, Jinrong Yao, Zhengzhong Shao, Peng Zhang, Jun Chen, Liang Zhou & Shiyi Chen
Pages: 4569-4580
Published online: 29 Sep 2014
AbstractforEnhancement of osseointegration of polyethylene terephthalate artificial ligament by coating of silk fibroin and depositing of hydroxyapatite | Full Text | References | PDF (5.9 MB)
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Article
A novel hydrolysis-resistant lipophilic folate derivative enables stable delivery of targeted liposomes in vivo
Yifei Huang, Tan Yang, Wendian Zhang, Yao Lu, Peng Ye, Guang Yang, Bin Li, Shibo Qi, Yong Liu, Xingxing He, Robert J Lee, Chuanrui Xu & Guangya Xiang
Pages: 4581-4595
Published online: 29 Sep 2014
AbstractforA novel hydrolysis-resistant lipophilic folate derivative enables stable delivery of targeted liposomes in vivo | Full Text | References | PDF (3.4 MB)
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Article
TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting
Feng-Ying Chen, Jing-Jing Yan, Han-Xi Yi, Fu-Qiang Hu, Yong-Zhong Du, Hong Yuan, Jian You & Meng-Dan Zhao
Pages: 4597-4608
Published online: 26 Sep 2014
AbstractforTNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting | Full Text | References | PDF (3.8 MB)
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Article
Chitosan-coated poly(lactic-co-glycolic) acid nanoparticles as an efficient delivery system for Newcastle disease virus DNA vaccine
Kai Zhao, Yang Zhang, Xiaoyan Zhang, Ci Shi, Xin Wang, Xiaohua Wang, Zheng Jin & Shangjin Cui
Pages: 4609-4619
Published online: 30 Sep 2014
AbstractforChitosan-coated poly(lactic-co-glycolic) acid nanoparticles as an efficient delivery system for Newcastle disease virus DNA vaccine | Full Text | References | PDF (1.9 MB)
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Article
Antibacterial activity and cytotoxicity of multi-walled carbon nanotubes decorated with silver nanoparticles
Youngmin Seo, Jangsun Hwang, Jieun Kim, Yoon Jeong, Mintai P Hwang & Jonghoon Choi
Pages: 4621-4629
Published online: 30 Sep 2014
AbstractforAntibacterial activity and cytotoxicity of multi-walled carbon nanotubes decorated with silver nanoparticles | Full Text | References | PDF (3 MB)
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Article
Covalent IR820-PEG-diamine nanoconjugates for theranostic applications in cancer
Alicia Fernandez-Fernandez, Romila Manchanda, Denny A Carvajal, Tingjun Lei, Supriya Srinivasan & Anthony J McGoron
Pages: 4631-4648
Published online: 06 Oct 2014
AbstractforCovalent IR820-PEG-diamine nanoconjugates for theranostic applications in cancer | Full Text | References | PDF (3 MB)
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Article
Immobilization of chitosan film containing semaphorin 3A onto a microarc oxidized titanium implant surface via silane reaction to improve MG63 osteogenic differentiation
Kaixiu Fang, Wen Song, Lifeng Wang, Sen Jia, Hongbo Wei, Shuai Ren, Xiaoru Xu & Yingliang Song
Pages: 4649-4657
Published online: 03 Oct 2014
AbstractforImmobilization of chitosan film containing semaphorin 3A onto a microarc oxidized titanium implant surface via silane reaction to improve MG63 osteogenic differentiation | Full Text | References | PDF (3.1 MB)
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Article
Atomic force microscopy fishing and mass spectrometry identification of gp120 on immobilized aptamers
Yuri D Ivanov, Natalia S Bukharina, Tatyana O Pleshakova, Pavel A Frantsuzov, Elena Yu Andreeva, Anna L Kaysheva, Victor G Zgoda, Alexander A Izotov, Tatyana I Pavlova, Vadim S Ziborov, Sergey P Radko, Sergei A Moshkovskii & Alexander I Archakov
Pages: 4659-4670
Published online: 03 Oct 2014
AbstractforAtomic force microscopy fishing and mass spectrometry identification of gp120 on immobilized aptamers | Full Text | References | PDF (4.7 MB)
  • 61 Views
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Article
Pulsed ultrasound enhances the delivery of nitric oxide from bubble liposomes to ex vivo porcine carotid tissue
JT Sutton, JL Raymond, MC Verleye, GJ Pyne-Geithman & CK Holland
Pages: 4671-4683
Published online: 06 Oct 2014
AbstractforPulsed ultrasound enhances the delivery of nitric oxide from bubble liposomes to ex vivo porcine carotid tissue | Full Text | References | PDF (1.2 MB)
  • 69 Views
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Article
The preparation and evaluation of self-nanoemulsifying systems containing Swietenia oil and an examination of its anti-inflammatory effects
Ahmad M Eid, Hesham A El-Enshasy, Ramlan Aziz & Nagib A Elmarzugi
Pages: 4685-4695
Published online: 07 Oct 2014
AbstractforThe preparation and evaluation of self-nanoemulsifying systems containing Swietenia oil and an examination of its anti-inflammatory effects | Full Text | References | PDF (2.3 MB)
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Article
Influence of polyethylene glycol coating on biodistribution and toxicity of nanoscale graphene oxide in mice after intravenous injection
Bo Li, Xiao-Yong Zhang, Jian-Zhong Yang, Yu-Jie Zhang, Wen-Xin Li, Chun-Hai Fan & Qing Huang
Pages: 4697-4707
Published online: 08 Oct 2014
AbstractforInfluence of polyethylene glycol coating on biodistribution and toxicity of nanoscale graphene oxide in mice after intravenous injection | Full Text | References | PDF (15.5 MB)
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Article
Biocomposite nanofibrous strategies for the controlled release of biomolecules for skin tissue regeneration
Chinnasamy Gandhimathi, Jayarama Reddy Venugopal, Velmurugan Bhaarathy, Seeram Ramakrishna & Srinivasan Dinesh Kumar
Pages: 4709-4722
Published online: 08 Oct 2014
AbstractforBiocomposite nanofibrous strategies for the controlled release of biomolecules for skin tissue regeneration | Full Text | References | PDF (7.4 MB)
  • 85 Views
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Article
Engineered andrographolide nanosystems for smart recovery in hepatotoxic conditions
Partha Roy, Suvadra Das, Runa Ghosh Auddy & Arup Mukherjee
Pages: 4723-4735
Published online: 09 Oct 2014
AbstractforEngineered andrographolide nanosystems for smart recovery in hepatotoxic conditions | Full Text | References | PDF (2.4 MB)
  • 77 Views
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Article
Factorial design applied to the optimization of lipid composition of topical antiherpetic nanoemulsions containing isoflavone genistein
Débora Fretes Argenta, Cristiane Bastos de Mattos, Fabíola Dallarosa Misturini, Leticia Scherer Koester, Valquiria Linck Bassani, Cláudia Maria Oliveira Simões & Helder Ferreira Teixeira
Pages: 4737-4747
Published online: 09 Oct 2014
AbstractforFactorial design applied to the optimization of lipid composition of topical antiherpetic nanoemulsions containing isoflavone genistein | Full Text | References | PDF (2 MB)
  • 102 Views
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Article
Development of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide
Bullo Saifullah, Palanisamy Arulselvan, Mohamed Ezzat El Zowalaty, Sharida Fakurazi, Thomas J Webster, Benjamin M Geilich & Mohd Zobir Hussein
Pages: 4749-4762
Published online: 09 Oct 2014
AbstractforDevelopment of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide | Full Text | References | PDF (3.7 MB)
  • 71 Views
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Article
Activation of Erk and p53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts
Cheng Luo, Yan Li, Liang Yang, Yan Zheng, Jiangang Long, Jinjing Jia, Shengxiang Xiao & Jiankang Liu
Pages: 4763-4772
Published online: 10 Oct 2014
AbstractforActivation of Erk and p53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts | Full Text | References | PDF (2.5 MB)
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Expert Opinion

Editorial
Development of Taiwan’s strategies for regulating nanotechnology-based pharmaceuticals harmonized with international considerations
Jiun-Wen Guo, Yu-Hsuan Lee, Hsiau-Wen Huang, Mei-Chyun Tzou, Ying-Jan Wang & Jui-Chen Tsai
Pages: 4773-4783
Published online: 15 Oct 2014
AbstractforDevelopment of Taiwan’s strategies for regulating nanotechnology-based pharmaceuticals harmonized with international considerations | Full Text | References | PDF (303.8 KB)
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Original Research

Article
Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery
Xianzhang Huang, Sujing Shen, Zhanfeng Zhang & Junhua Zhuang
Pages: 4785-4794
Published online: 16 Oct 2014
AbstractforCross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery | Full Text | References | PDF (2.2 MB)
  • 91 Views
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Article
Siliceous mesostructured cellular foams/poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) composite biomaterials for bone regeneration
Shengbing Yang, Shuogui Xu, Panyu Zhou, Jing Wang, Honglue Tan, Yang Liu, TingTing Tang & ChangSheng Liu
Pages: 4795-4807
Published online: 20 Oct 2014
AbstractforSiliceous mesostructured cellular foams/poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) composite biomaterials for bone regeneration | Full Text | References | PDF (6.9 MB)
  • 49 Views
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Article
Toxicity assessment of repeated intravenous injections of arginine–glycine–aspartic acid peptide conjugated CdSeTe/ZnS quantum dots in mice
You-Wei Wang, Kai Yang, Hong Tang, Dan Chen & Yun-Long Bai
Pages: 4809-4817
Published online: 17 Oct 2014
AbstractforToxicity assessment of repeated intravenous injections of arginine–glycine–aspartic acid peptide conjugated CdSeTe/ZnS quantum dots in mice | Full Text | References | PDF (1.3 MB)
  • 56 Views
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Article
Chitosan-decorated selenium nanoparticles as protein carriers to improve the in vivo half-life of the peptide therapeutic BAY 55-9837 for type 2 diabetes mellitus
Lei Rao, Yi Ma, Manjiao Zhuang, Tianjie Luo, Yayu Wang & An Hong
Pages: 4819-4828
Published online: 17 Oct 2014
AbstractforChitosan-decorated selenium nanoparticles as protein carriers to improve the in vivo half-life of the peptide therapeutic BAY 55-9837 for type 2 diabetes mellitus | Full Text | References | PDF (2.3 MB)
  • 129 Views
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Article
Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity
Qing Yuan, Jing Han, Wenshu Cong, Ying Ge, Dandan Ma, Zhaoxia Dai, Yaping Li & Xiaolin Bi
Pages: 4829-4846
Published online: 17 Oct 2014
AbstractforDocetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity | Full Text | References | PDF (7.1 MB)
  • 145 Views
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Article
Development of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility
Jan Zaloga, Christina Janko, Johannes Nowak, Jasmin Matuszak, Sabine Knaup, Dietmar Eberbeck, Rainer Tietze, Harald Unterweger, Ralf P Friedrich, Stephan Duerr, Ralph Heimke-Brinck, Eva Baum, Iwona Cicha, Frank Dörje, Stefan Odenbach, Stefan Lyer, Geoffrey Lee & Christoph Alexiou
Pages: 4847-4866
Published online: 20 Oct 2014
AbstractforDevelopment of a lauric acid/albumin hybrid iron oxide nanoparticle system with improved biocompatibility | Full Text | References | PDF (6 MB)
  • 138 Views
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Article
Improvement of pharmacokinetic and antitumor activity of layered double hydroxide nanoparticles by coating with PEGylated phospholipid membrane
Mina Yan, Zhaoguo Zhang, Shengmiao Cui, Ming Lei, Ke Zeng, Yunhui Liao, Weijing Chu, Yihui Deng & Chunshun Zhao
Pages: 4867-4878
Published online: 21 Oct 2014
AbstractforImprovement of pharmacokinetic and antitumor activity of layered double hydroxide nanoparticles by coating with PEGylated phospholipid membrane | Full Text | References | PDF (3.2 MB)
  • 93 Views
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Article
Magnetic-luminescent YbPO4:Er,Dy microspheres designed for tumor theranostics with synergistic effect of photodynamic therapy and chemotherapy
Wei Wang, Dong Xu, Xiaojun Wei & Kezheng Chen
Pages: 4879-4891
Published online: 20 Oct 2014
AbstractforMagnetic-luminescent YbPO4:Er,Dy microspheres designed for tumor theranostics with synergistic effect of photodynamic therapy and chemotherapy | Full Text | References | PDF (4.1 MB)
  • 55 Views
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Short Report

Brief Report
Neural stem cell-derived exosomes mediate viral entry
Brian Sims, Linlin Gu, Alexandre Krendelchtchikov & Qiana L Matthews
Pages: 4893-4897
Published online: 21 Oct 2014
AbstractforNeural stem cell-derived exosomes mediate viral entry | Full Text | References | PDF (833.3 KB)
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Original Research

Article
Microbubbles coupled to methotrexate-loaded liposomes for ultrasound-mediated delivery of methotrexate across the blood–brain barrier
Xiang Wang, Ping Liu, Weixiao Yang, Lu Li, Peijing Li, Zheng Liu, Zhongxiong Zhuo & Yunhua Gao
Pages: 4899-4909
Published online: 23 Oct 2014
AbstractforMicrobubbles coupled to methotrexate-loaded liposomes for ultrasound-mediated delivery of methotrexate across the blood–brain barrier | Full Text | References | PDF (2.3 MB)
  • 82 Views
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Article
Co-association of methotrexate and SPIONs into anti-CD64 antibody-conjugated PLGA nanoparticles for theranostic application
Catarina Costa Moura, Marcela A Segundo, José das Neves, Salette Reis & Bruno Sarmento
Pages: 4911-4922
Published online: 23 Oct 2014
AbstractforCo-association of methotrexate and SPIONs into anti-CD64 antibody-conjugated PLGA nanoparticles for theranostic application | Full Text | References | PDF (9.5 MB)
  • 172 Views
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Article
Self-assembled micelles based on pH-sensitive PAE-g-MPEG-cholesterol block copolymer for anticancer drug delivery
Can Yang Zhang, Di Xiong, Yao Sun, Bin Zhao, Wen Jing Lin & Li Juan Zhang
Pages: 4923-4933
Published online: 23 Oct 2014
AbstractforSelf-assembled micelles based on pH-sensitive PAE-g-MPEG-cholesterol block copolymer for anticancer drug delivery | Full Text | References | PDF (2.6 MB)
  • 89 Views
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Article
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities
Vanna Sanna, Nicolino Pala, Giuseppina Dessì, Paola Manconi, Alberto Mariani, Sonia Dedola, Mauro Rassu, Claudia Crosio, Ciro Iaccarino & Mario Sechi
Pages: 4935-4951
Published online: 23 Oct 2014
AbstractforSingle-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities | Full Text | References | PDF (5.8 MB)
  • 347 Views
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Article
Determination of factors controlling the particle size and entrapment efficiency of noscapine in PEG/PLA nanoparticles using artificial neural networks
Karim S Shalaby, Mahmoud E Soliman, Luca Casettari, Giulia Bonacucina, Marco Cespi, Giovanni F Palmieri, Omaima A Sammour & Abdelhameed A El Shamy
Pages: 4953-4964
Published online: 23 Oct 2014
AbstractforDetermination of factors controlling the particle size and entrapment efficiency of noscapine in PEG/PLA nanoparticles using artificial neural networks | Full Text | References | PDF (3.3 MB)
  • 197 Views
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Article
The sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles
Yun Wang, Fu-xing Lin, Yu Zhao, Mo-zhen Wang, Xue-wu Ge, Zheng-xing Gong, Dan-dan Bao & Yu-fang Gu
Pages: 4965-4978
Published online: 23 Oct 2014
AbstractforThe sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles | Full Text | References | PDF (5.4 MB)
  • 49 Views
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Article
Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid
Mariana Magalhães, Dina Farinha, Maria Conceição Pedroso de Lima & Henrique Faneca
Pages: 4979-4989
Published online: 24 Oct 2014
AbstractforIncreased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid | Full Text | References | PDF (1.7 MB)
  • 52 Views
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Article
Enhancement of oral bioavailability of cyclosporine A: comparison of various nanoscale drug-delivery systems
Kai Wang, Jianping Qi, Tengfei Weng, Zhiqiang Tian, Yi Lu, Kaili Hu, Zongning Yin & Wei Wu
Pages: 4991-4999
Published online: 28 Oct 2014
AbstractforEnhancement of oral bioavailability of cyclosporine A: comparison of various nanoscale drug-delivery systems | Full Text | References | PDF (3.7 MB)
  • 159 Views
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Article
Gum arabic-coated radioactive gold nanoparticles cause no short-term local or systemic toxicity in the clinically relevant canine model of prostate cancer
Sandra M Axiak-Bechtel, Anandhi Upendran, Jimmy C Lattimer, James Kelsey, Cathy S Cutler, Kim A Selting, Jeffrey N Bryan, Carolyn J Henry, Evan Boote, Deborah J Tate, Margaret E Bryan, Kattesh V Katti & Raghuraman Kannan
Pages: 5001-5011
Published online: 28 Oct 2014
AbstractforGum arabic-coated radioactive gold nanoparticles cause no short-term local or systemic toxicity in the clinically relevant canine model of prostate cancer | Full Text | References | PDF (1 MB)
  • 129 Views
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Article
Controllably local gene delivery mediated by polyelectrolyte multilayer films assembled from gene-loaded nanopolymersomes and hyaluronic acid
Wei Teng, Qinmei Wang, Ying Chen & Hongzhang Huang
Pages: 5013-5024
Published online: 29 Oct 2014
AbstractforControllably local gene delivery mediated by polyelectrolyte multilayer films assembled from gene-loaded nanopolymersomes and hyaluronic acid | Full Text | References | PDF (2.7 MB)
  • 41 Views
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Article
Biological impact of superparamagnetic iron oxide nanoparticles for magnetic particle imaging of head and neck cancer cells
Antje Lindemann, Kerstin Lüdtke-Buzug, Bianca M Fräderich, Ksenija Gräfe, Ralph Pries & Barbara Wollenberg
Pages: 5025-5040
Published online: 29 Oct 2014
AbstractforBiological impact of superparamagnetic iron oxide nanoparticles for magnetic particle imaging of head and neck cancer cells | Full Text | References | PDF (8.2 MB)
  • 92 Views
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Article
Synthesis and characterization of bioactive conjugated near-infrared fluorescent proteinoid-poly(L-lactic acid) hollow nanoparticles for optical detection of colon cancer
Michal Kolitz-Domb, Enav Corem-Salkmon, Igor Grinberg & Shlomo Margel
Pages: 5041-5053
Published online: 31 Oct 2014
AbstractforSynthesis and characterization of bioactive conjugated near-infrared fluorescent proteinoid-poly(L-lactic acid) hollow nanoparticles for optical detection of colon cancer | Full Text | References | PDF (2.1 MB)
  • 51 Views
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Article
Clavanin bacterial sepsis control using a novel methacrylate nanocarrier
Amanda CM Saúde, Alicia S Ombredane, Osmar N Silva, João ARG Barbosa, Susana E Moreno, Ana Claudia Guerra Araujo, Rosana Falcão, Luciano P Silva, Simoni C Dias & Octávio L Franco
Pages: 5055-5069
Published online: 31 Oct 2014
AbstractforClavanin bacterial sepsis control using a novel methacrylate nanocarrier | Full Text | References | PDF (2 MB)
  • 59 Views
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Article
Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
Weiwei Guan, Wei Gu, Ling Ye, Chenyang Guo, Su Su, Pinxiang Xu & Ming Xue
Pages: 5071-5078
Published online: 31 Oct 2014
AbstractforMicrowave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging | Full Text | References | PDF (1.2 MB)
  • 127 Views
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Article
Preparation and evaluation of cyclosporin A-containing proliposomes: a comparison of the supercritical antisolvent process with the conventional film method
Pankaj Ranjan Karn, Su-Eon Jin, Benjamin Joon Lee, Bo Kyung Sun, Min-Soo Kim, Jong-Hyuk Sung & Sung-Joo Hwang
Pages: 5079-5091
Published online: 03 Nov 2014
AbstractforPreparation and evaluation of cyclosporin A-containing proliposomes: a comparison of the supercritical antisolvent process with the conventional film method | Full Text | References | PDF (4 MB)
  • 85 Views
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Article
A histological evaluation and in vivo assessment of intratumoral near infrared photothermal nanotherapy-induced tumor regression
Hadiyah N Green, Stephanie D Crockett, Dmitry V Martyshkin, Karan P Singh, William E Grizzle, Eben L Rosenthal & Sergey B Mirov
Pages: 5093-5102
Published online: 05 Nov 2014
AbstractforA histological evaluation and in vivo assessment of intratumoral near infrared photothermal nanotherapy-induced tumor regression | Full Text | References | PDF (2.4 MB)
  • 83 Views
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Article
Stable cerasomes for simultaneous drug delivery and magnetic resonance imaging
Zhong Cao, Wenjian Zhu, Wei Wang, Chunyang Zhang, Ming Xu, Jie Liu, Shi-Ting Feng, Qing Jiang & Xiaoyan Xie
Pages: 5103-5116
Published online: 05 Nov 2014
AbstractforStable cerasomes for simultaneous drug delivery and magnetic resonance imaging | Full Text | References | PDF (3.5 MB)
  • 50 Views
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Article
Stabilization of collagen nanofibers with l-lysine improves the ability of carbodiimide cross-linked amniotic membranes to preserve limbal epithelial progenitor cells
Jui-Yang Lai, Pei-Ran Wang, Li-Jyuan Luo & Si-Tan Chen
Pages: 5117-5130
Published online: 05 Nov 2014
AbstractforStabilization of collagen nanofibers with l-lysine improves the ability of carbodiimide cross-linked amniotic membranes to preserve limbal epithelial progenitor cells | Full Text | References | PDF (5.6 MB)
  • 86 Views
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Article
Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway
Junchao Duan, Yongbo Yu, Yang Yu, Yang Li, Ji Wang, Weijia Geng, Lizhen Jiang, Qiuling Li, Xianqing Zhou & Zhiwei Sun
Pages: 5131-5141
Published online: 05 Nov 2014
AbstractforSilica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway | Full Text | References | PDF (1.7 MB)
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Article
Downregulation of immunological mediators in 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions by hydrocortisone-loaded chitosan nanoparticles
Zahid Hussain, Haliza Katas, Mohd Cairul Iqbal Mohd Amin, Endang Kumolosasi & Shariza Sahudin
Pages: 5143-5156
Published online: 05 Nov 2014
AbstractforDownregulation of immunological mediators in 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions by hydrocortisone-loaded chitosan nanoparticles | Full Text | References | PDF (3.3 MB)
  • 107 Views
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Article
Upconversion nanoparticles conjugated with curcumin as a photosensitizer to inhibit methicillin-resistant Staphylococcus aureus in lung under near infrared light
Yong Ye, Yue Li & Fei Fang
Pages: 5157-5165
Published online: 06 Nov 2014
AbstractforUpconversion nanoparticles conjugated with curcumin as a photosensitizer to inhibit methicillin-resistant Staphylococcus aureus in lung under near infrared light | Full Text | References | PDF (2 MB)
  • 102 Views
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Article
Fabrication and evaluation of valsartan–polymer– surfactant composite nanoparticles by using the supercritical antisolvent process
Min-Soo Kim & In-hwan Baek
Pages: 5167-5176
Published online: 07 Nov 2014
AbstractforFabrication and evaluation of valsartan–polymer– surfactant composite nanoparticles by using the supercritical antisolvent process | Full Text | References | PDF (3.4 MB)
  • 89 Views
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Article
Facile electrochemical synthesis of antimicrobial TiO2 nanotube arrays
Yu Zhao, Qi Xing, Jagadeesh Janjanam, Kun He, Fei Long, Ke-Bin Low, Ashutosh Tiwari, Feng Zhao, Reza Shahbazian-Yassar, Craig Friedrich & Tolou Shokuhfar
Pages: 5177-5187
Published online: 11 Nov 2014
AbstractforFacile electrochemical synthesis of antimicrobial TiO2 nanotube arrays | Full Text | References | PDF (5.6 MB)
  • 87 Views
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Article
Engineered collagen hydrogels for the sustained release of biomolecules and imaging agents: promoting the growth of human gingival cells
Jonghoon Choi, Hoyoung Park, Taeho Kim, Yoon Jeong, Myoung Hwan Oh, Taeghwan Hyeon, Assaf A Gilad & Kwan Hyi Lee
Pages: 5189-5201
Published online: 11 Nov 2014
AbstractforEngineered collagen hydrogels for the sustained release of biomolecules and imaging agents: promoting the growth of human gingival cells | Full Text | References | PDF (3.8 MB)
  • 79 Views
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Article
Nanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair
Kai Zhu, Hao Lai, Changfa Guo, Jun Li, Yulin Wang, Lingyan Wang & Chunsheng Wang
Pages: 5203-5215
Published online: 11 Nov 2014
AbstractforNanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair | Full Text | References | PDF (3.5 MB)
  • 52 Views
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Article
Effects of adsorbed and templated nanosilver in mesoporous calcium-silicate nanoparticles on inhibition of bacteria colonization of dentin
Wei Fan, Daming Wu, Franklin R Tay, Tengjiao Ma, Yujie Wu & Bing Fan
Pages: 5217-5230
Published online: 12 Nov 2014
AbstractforEffects of adsorbed and templated nanosilver in mesoporous calcium-silicate nanoparticles on inhibition of bacteria colonization of dentin | Full Text | References | PDF (11.6 MB)
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Article
Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen
Sandeep S Saluja, Douglas J Hanlon, Fiona A Sharp, Enping Hong, David Khalil, Eve Robinson, Robert Tigelaar, Tarek M Fahmy & Richard L Edelson
Pages: 5231-5246
Published online: 12 Nov 2014
AbstractforTargeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen | Full Text | References | PDF (5.1 MB)
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Article
Enhanced antidepressant-like effects of the macromolecule trefoil factor 3 by loading into negatively charged liposomes
Jing Qin, Xu Yang, Jia Mi, Jianxin Wang, Jia Hou, Teng Shen, Yongji Li, Bin Wang, Xuri Li & Weili Zhu
Pages: 5247-5257
Published online: 12 Nov 2014
AbstractforEnhanced antidepressant-like effects of the macromolecule trefoil factor 3 by loading into negatively charged liposomes | Full Text | References | PDF (748.4 KB)
  • 62 Views
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Letter

Letter
Inhibition of oxygen scavengers realized by peritoneal macrophages: an adhesion prevention target?
Ospan A Mynbaev, Marina Yu Eliseeva, Oktay T Kadayifci, Tahar Benhidjeb & Michael Stark
Pages: 5259-5260
Published online: 14 Nov 2014
CitationforInhibition of oxygen scavengers realized by peritoneal macrophages: an adhesion prevention target? | Full Text | References | PDF (188.6 KB)
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Original Research

Article
Polyethylene glycol–polylactic acid nanoparticles modified with cysteine–arginine–glutamic acid–lysine–alanine fibrin-homing peptide for glioblastoma therapy by enhanced retention effect
Junzhu Wu, Jingjing Zhao, Bo Zhang, Yong Qian, Huile Gao, Yuan Yu, Yan Wei, Zhi Yang, Xinguo Jiang & Zhiqing Pang
Pages: 5261-5271
Published online: 13 Nov 2014
AbstractforPolyethylene glycol–polylactic acid nanoparticles modified with cysteine–arginine–glutamic acid–lysine–alanine fibrin-homing peptide for glioblastoma therapy by enhanced retention effect | Full Text | References | PDF (5.1 MB)
  • 79 Views
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Letter

Letter
Cytotoxic effects of curcumin in osteosarcoma cells
JM Moran, FJ Rodriguez-Velasco, R Roncero-Martin, V Vera & JD Pedrera-Zamorano
Pages: 5273-5275
Published online: 14 Nov 2014
First Page PreviewforCytotoxic effects of curcumin in osteosarcoma cells | Full Text | References | PDF (125.8 KB)
  • 45 Views
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Original Research

Article
Effect of silk fibroin nanofibers containing silver sulfadiazine on wound healing
Lim Jeong, Min Hee Kim, Ju-Young Jung, Byung Moo Min & Won Ho Park
Pages: 5277-5287
Published online: 14 Nov 2014
AbstractforEffect of silk fibroin nanofibers containing silver sulfadiazine on wound healing | Full Text | References | PDF (5.8 MB)
  • 118 Views
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Article
Nanotechnology versus stem cell engineering: in vitro comparison of neurite inductive potentials
Michela Morano, Sandra Wrobel, Federica Fregnan, Ofra Ziv-Polat, Abraham Shahar, Andreas Ratzka, Claudia Grothe, Stefano Geuna & Kirsten Haastert-Talini
Pages: 5289-5306
Published online: 14 Nov 2014
AbstractforNanotechnology versus stem cell engineering: in vitro comparison of neurite inductive potentials | Full Text | References | PDF (7.3 MB)
  • 80 Views
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Article
Incorporation of osteogenic and angiogenic small interfering RNAs into chitosan sponge for bone tissue engineering
Sen Jia, Xinjie Yang, Wen Song, Lei Wang, Kaixiu Fang, Zhiqiang Hu, Zihui Yang, Chun Shan, Delin Lei & Bin Lu
Pages: 5307-5316
Published online: 17 Nov 2014
AbstractforIncorporation of osteogenic and angiogenic small interfering RNAs into chitosan sponge for bone tissue engineering | Full Text | References | PDF (4.8 MB)
  • 74 Views
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Article
Autologous serum improves bone formation in a primary stable silica-embedded nanohydroxyapatite bone substitute in combination with mesenchymal stem cells and rhBMP-2 in the sheep model
Anja M Boos, Annika Weigand, Gloria Deschler, Thomas Gerber, Andreas Arkudas, Ulrich Kneser, Raymund E Horch & Justus P Beier
Pages: 5317-5339
Published online: 19 Nov 2014
AbstractforAutologous serum improves bone formation in a primary stable silica-embedded nanohydroxyapatite bone substitute in combination with mesenchymal stem cells and rhBMP-2 in the sheep model | Full Text | References | PDF (8.7 MB)
  • 57 Views
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Article
An optimized nanoparticle delivery system based on chitosan and chondroitin sulfate molecules reduces the toxicity of amphotericin B and is effective in treating tegumentary leishmaniasis
Tatiana G Ribeiro, Juçara R Franca, Leonardo L Fuscaldi, Mara L Santos, Mariana C Duarte, Paula S Lage, Vivian T Martins, Lourena E Costa, Simone OA Fernandes, Valbert N Cardoso, Rachel O Castilho, Manuel Soto, Carlos AP Tavares, André AG Faraco, Eduardo AF Coelho & Miguel A Chávez-Fumagalli
Pages: 5341-5353
Published online: 19 Nov 2014
AbstractforAn optimized nanoparticle delivery system based on chitosan and chondroitin sulfate molecules reduces the toxicity of amphotericin B and is effective in treating tegumentary leishmaniasis | Full Text | References | PDF (3.5 MB)
  • 96 Views
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Article
Mesenchymal stromal cell labeling by new uncoated superparamagnetic maghemite nanoparticles in comparison with commercial Resovist – an initial in vitro study
Josef Skopalik, Katerina Polakova, Marketa Havrdova, Ivan Justan, Massimiliano Magro, David Milde, Lucia Knopfova, Jan Smarda, Helena Polakova, Eva Gabrielova, Fabio Vianello, Jaroslav Michalek & Radek Zboril
Pages: 5355-5372
Published online: 20 Nov 2014
AbstractforMesenchymal stromal cell labeling by new uncoated superparamagnetic maghemite nanoparticles in comparison with commercial Resovist – an initial in vitro study | Full Text | References | PDF (6.3 MB)
  • 50 Views
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Article
Formulation of nanotized curcumin and demonstration of its antimalarial efficacy
Aparajita Ghosh, Tanushree Banerjee, Suman Bhandary & Avadhesha Surolia
Pages: 5373-5387
Published online: 20 Nov 2014
AbstractforFormulation of nanotized curcumin and demonstration of its antimalarial efficacy | Full Text | References | PDF (5.8 MB)
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Article
Proliferation and stemness preservation of human adipose-derived stem cells by surface-modified in situ TiO2 nanofibrous surfaces
Ai Wen Tan, Lelia Tay, Kien Hui Chua, Roslina Ahmad, Sheikh Ali Akbar & Belinda Pingguan-Murphy
Pages: 5389-5401
Published online: 21 Nov 2014
AbstractforProliferation and stemness preservation of human adipose-derived stem cells by surface-modified in situ TiO2 nanofibrous surfaces | Full Text | References | PDF (4.4 MB)
  • 65 Views
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Article
Enhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo
Xiaolong Tang, He Zhu, Ledong Sun, Wei Hou, Shuyu Cai, Rongbo Zhang & Feng Liu
Pages: 5403-5413
Published online: 24 Nov 2014
AbstractforEnhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo | Full Text | References | PDF (3.8 MB)
  • 79 Views
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Article
Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications
Florian Correard, Ksenia Maximova, Marie-Anne Estève, Claude Villard, Myriam Roy, Ahmed Al-Kattan, Marc Sentis, Marc Gingras, Andrei V Kabashin & Diane Braguer
Pages: 5415-5430
Published online: 21 Nov 2014
AbstractforGold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications | Full Text | References | PDF (5 MB)
  • 176 Views
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Article
Study on the prostate cancer-targeting mechanism of aptamer-modified nanoparticles and their potential anticancer effect in vivo
Xin Wu, Zongguang Tai, Quangang Zhu, Wei Fan, Baoyue Ding, Wei Zhang, Lijuan Zhang, Chong Yao, Xiaoyu Wang, Xueying Ding, Qin Li, Xiaoyu Li, Gaolin Liu, Jiyong Liu & Shen Gao
Pages: 5431-5440
Published online: 21 Nov 2014
AbstractforStudy on the prostate cancer-targeting mechanism of aptamer-modified nanoparticles and their potential anticancer effect in vivo | Full Text | References | PDF (2.9 MB)
  • 78 Views
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Article
Cytotoxicity of gold nanoclusters in human liver cancer cells
Yanjie Yang, Jing Nan, Jianwen Hou, Bianfei Yu, Tong Zhao, Shuang Xu, Shuangyu Lv & Haixia Zhang
Pages: 5441-5448
Published online: 25 Nov 2014
AbstractforCytotoxicity of gold nanoclusters in human liver cancer cells | Full Text | References | PDF (1.5 MB)
  • 61 Views
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Article
Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia
Rehab Nabil Shamma & Mona Hassan Aburahma
Pages: 5449-5460
Published online: 26 Nov 2014
AbstractforFollicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia | Full Text | References | PDF (2.9 MB)
  • 154 Views
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Article
Inhibitory effect of gold nanoparticles on the D-ribose glycation of bovine serum albumin
Weixi Liu, Menashi A Cohenford, Leslie Frost, Champika Seneviratne & Joel A Dain
Pages: 5461-5469
Published online: 26 Nov 2014
AbstractforInhibitory effect of gold nanoparticles on the D-ribose glycation of bovine serum albumin | Full Text | References | PDF (1.6 MB)
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Article
Pharmacokinetics on a microscale: visualizing Cy5-labeled oligonucleotide release from poly(n-butylcyanoacrylate) nanocapsules in cells
Stephanie Tomcin, Grit Baier, Katharina Landfester & Volker Mailänder
Pages: 5471-5489
Published online: 26 Nov 2014
AbstractforPharmacokinetics on a microscale: visualizing Cy5-labeled oligonucleotide release from poly(n-butylcyanoacrylate) nanocapsules in cells | Full Text | References | PDF (7.7 MB)
  • 79 Views
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Article
Enhanced stability and antibacterial efficacy of a traditional Chinese medicine-mediated silver nanoparticle delivery system
Wenjie Sun, Ding Qu, Yihua Ma, Yan Chen, Congyan Liu & Jing Zhou
Pages: 5491-5502
Published online: 26 Nov 2014
AbstractforEnhanced stability and antibacterial efficacy of a traditional Chinese medicine-mediated silver nanoparticle delivery system | Full Text | References | PDF (2.6 MB)
  • 76 Views
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Article
Effects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: a mechanistic investigation
Xingwang Zhang, Guijiang Chen, Tianpeng Zhang, Zhiguo Ma & Baojian Wu
Pages: 5503-5514
Published online: 26 Nov 2014
AbstractforEffects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: a mechanistic investigation | Full Text | References | PDF (7.7 MB)
  • 103 Views
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Article
Cytotoxicity and antibacterial activity of gold-supported cerium oxide nanoparticles
K Suresh Babu, M Anandkumar, TY Tsai, TH Kao, B Stephen Inbaraj & BH Chen
Pages: 5515-5531
Published online: 27 Nov 2014
AbstractforCytotoxicity and antibacterial activity of gold-supported cerium oxide nanoparticles | Full Text | References | PDF (3.6 MB)
  • 303 Views
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Article
Greater cardiomyocyte density on aligned compared with random carbon nanofibers in polymer composites
Abdullah M Asiri, Hadi M Marwani, Sher Bahadar Khan & Thomas J Webster
Pages: 5533-5539
Published online: 28 Nov 2014
AbstractforGreater cardiomyocyte density on aligned compared with random carbon nanofibers in polymer composites | Full Text | References | PDF (1.1 MB)
  • 47 Views
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Article
A novel diblock of copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells
Vahid Erfani-Moghadam, Alireza Nomani, Mina Zamani, Yaghoub Yazdani, Farhood Najafi & Majid Sadeghizadeh
Pages: 5541-5554
Published online: 28 Nov 2014
AbstractforA novel diblock of copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells | Full Text | References | PDF (8 MB)
  • 104 Views
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Article
Injectable long-acting systems for Radix Ophiopogonis polysaccharide based on mono-PEGylation and in situ formation of a PLGA depot
XiaoLi Shi, Xiao Lin, XiangWei Zheng, Yi Feng & Lan Shen
Pages: 5555-5563
Published online: 28 Nov 2014
AbstractforInjectable long-acting systems for Radix Ophiopogonis polysaccharide based on mono-PEGylation and in situ formation of a PLGA depot | Full Text | References | PDF (522.4 KB)
  • 69 Views
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Article
Surface characteristics of and in vitro behavior of osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening
Zhennan Deng, Baodi Yin, Weihong Li, Jinsong Liu, Jingyuan Yang, Tieli Zheng, Dafeng Zhang, Haiyang Yu, Xiaoguang Liu & Jianfeng Ma
Pages: 5565-5573
Published online: 28 Nov 2014
AbstractforSurface characteristics of and in vitro behavior of osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening | Full Text | References | PDF (7.5 MB)
  • 58 Views
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Article
Noninvasive detection of macrophages in atherosclerotic lesions by computed tomography enhanced with PEGylated gold nanoparticles
Jinbao Qin, Chen Peng, Binghui Zhao, Kaichuang Ye, Fukang Yuan, Zhiyou Peng, Xinrui Yang, Lijia Huang, Mier Jiang, Qinghua Zhao, Guangyu Tang & Xinwu Lu
Pages: 5575-5590
Published online: 02 Dec 2014
AbstractforNoninvasive detection of macrophages in atherosclerotic lesions by computed tomography enhanced with PEGylated gold nanoparticles | Full Text | References | PDF (11.3 MB)
  • 58 Views
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Article
Enhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration
Hui Cai, Xingxing Wen, Lu Wen, Nicola Tirelli, Xiao Zhang, Yue Zhang, Huanpeng Su, Fan Yang & Gang Chen
Pages: 5591-5601
Published online: 01 Dec 2014
AbstractforEnhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration | Full Text | References | PDF (2 MB)
  • 98 Views
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Article
Induction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles
Li Pan, Zhongwang Zhang, Jianliang Lv, Peng Zhou, Wenfa Hu, Yuzhen Fang, Haotai Chen, Xinsheng Liu, Junjun Shao, Furong Zhao, Yaozhong Ding, Tong Lin, Huiyun Chang, Jie Zhang, Yongguang Zhang & Yonglu Wang
Pages: 5603-5618
Published online: 02 Dec 2014
AbstractforInduction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles | Full Text | References | PDF (1.4 MB)
  • 69 Views
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Article
Rapid and quantitative detection of C-reactive protein using quantum dots and immunochromatographic test strips
Xianglin Cheng, Xu Pu, Pen Jun, XiaoBo Zhu, Di Zhu & Ming Chen
Pages: 5619-5626
Published online: 02 Dec 2014
AbstractforRapid and quantitative detection of C-reactive protein using quantum dots and immunochromatographic test strips | Full Text | References | PDF (1.3 MB)
  • 137 Views
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Article
Similar healthy osteoclast and osteoblast activity on nanocrystalline hydroxyapatite and nanoparticles of tri-calcium phosphate compared to natural bone
Adam K MacMillan, Francis V Lamberti, Julia N Moulton, Benjamin M Geilich & Thomas J Webster
Pages: 5627-5637
Published online: 02 Dec 2014
AbstractforSimilar healthy osteoclast and osteoblast activity on nanocrystalline hydroxyapatite and nanoparticles of tri-calcium phosphate compared to natural bone | Full Text | References | PDF (5.8 MB)
  • 87 Views
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Article
Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats
Shengzheng Wu, Lu Li, Gong Wang, Weiwei Shen, Yali Xu, Zheng Liu, Zhongxiong Zhuo, Hongmei Xia, Yunhua Gao & Kaibin Tan
Pages: 5639-5651
Published online: 03 Dec 2014
AbstractforUltrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats | Full Text | References | PDF (13.1 MB)
  • 81 Views
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Article
Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer
Armando Lucero-Acuña, Justin J Jeffery, Edward R Abril, Raymond B Nagle, Roberto Guzman, Mark D Pagel & Emmanuelle J Meuillet
Pages: 5653-5665
Published online: 03 Dec 2014
AbstractforNanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer | Full Text | References | PDF (3.6 MB)
  • 72 Views
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Article
Fluorescence tomographic imaging of sentinel lymph node using near-infrared emitting bioreducible dextran nanogels
Jiejing Li, Beiqi Jiang, Chao Lin & Zhigang Zhuang
Pages: 5667-5682
Published online: 04 Dec 2014
AbstractforFluorescence tomographic imaging of sentinel lymph node using near-infrared emitting bioreducible dextran nanogels | Full Text | References | PDF (8.4 MB)
  • 57 Views
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Article
Immunoliposome co-delivery of bufalin and anti-CD40 antibody adjuvant induces synergetic therapeutic efficacy against melanoma
Ying Li, Jiani Yuan, Qian Yang, Wei Cao, Xuanxuan Zhou, Yanhua Xie, Honghai Tu, Ya Zhang & Siwang Wang
Pages: 5683-5700
Published online: 04 Dec 2014
AbstractforImmunoliposome co-delivery of bufalin and anti-CD40 antibody adjuvant induces synergetic therapeutic efficacy against melanoma | Full Text | References | PDF (3.8 MB)
  • 81 Views
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Article
In vitro antioxidant activity and in vivo antifatigue effect of layered double hydroxide nanoparticles as delivery vehicles for folic acid
Lili Qin, Wenrui Wang, Songhui You, Jingmei Dong, Yunhe Zhou & Jibing Wang
Pages: 5701-5710
Published online: 04 Dec 2014
AbstractforIn vitro antioxidant activity and in vivo antifatigue effect of layered double hydroxide nanoparticles as delivery vehicles for folic acid | Full Text | References | PDF (1.6 MB)
  • 127 Views
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Article
Preparation and characterization of self-assembled nanoparticles based on low-molecular-weight heparin and stearylamine conjugates for controlled delivery of docetaxel
Dong-Hwan Kim, Ubonvan Termsarasab, Hyun-Jong Cho, In-Soo Yoon, Jae-Young Lee, Hyun Tae Moon & Dae-Duk Kim
Pages: 5711-5727
Published online: 08 Dec 2014
AbstractforPreparation and characterization of self-assembled nanoparticles based on low-molecular-weight heparin and stearylamine conjugates for controlled delivery of docetaxel | Full Text | References | PDF (3.3 MB)
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Review Article
Closing the gap: accelerating the translational process in nanomedicine by proposing standardized characterization techniques
Ali A Khorasani, James L Weaver & Carolina Salvador-Morales
Pages: 5729-5751
Published online: 08 Dec 2014
AbstractforClosing the gap: accelerating the translational process in nanomedicine by proposing standardized characterization techniques | Full Text | References | PDF (433.1 KB)
  • 81 Views
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Article
Selective inhibition of liver cancer growth realized by the intrinsic toxicity of a quantum dot–lipid complex
Dan Shao, Jing Li, Fengying Guan, Yue Pan, Xuanang Xiao, Ming Zhang, Hong Zhang & Li Chen
Pages: 5753-5769
Published online: 08 Dec 2014
AbstractforSelective inhibition of liver cancer growth realized by the intrinsic toxicity of a quantum dot–lipid complex | Full Text | References | PDF (7.8 MB)
  • 55 Views
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Article
Quantum dots immunofluorescence histochemical detection of EGFR gene mutations in the non-small cell lung cancers using mutation-specific antibodies
Yan-Gang Qu, Qian Zhang, Qi Pan, Xian-Da Zhao, Yan-Hua Huang, Fu-Chun Chen & Hong-Lei Chen
Pages: 5771-5778
Published online: 09 Dec 2014
AbstractforQuantum dots immunofluorescence histochemical detection of EGFR gene mutations in the non-small cell lung cancers using mutation-specific antibodies | Full Text | References | PDF (3.8 MB)
  • 76 Views
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Article
Influence of nanoparticles on color stability, microhardness, and flexural strength of acrylic resins specific for ocular prosthesis
Agda Marobo Andreotti, Marcelo Coelho Goiato, Amália Moreno, Adhara Smith Nobrega, Aldiéris Alves Pesqueira & Daniela Micheline dos Santos
Pages: 5779-5787
Published online: 10 Dec 2014
AbstractforInfluence of nanoparticles on color stability, microhardness, and flexural strength of acrylic resins specific for ocular prosthesis | Full Text | References | PDF (411.6 KB)
  • 117 Views
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Review

Review Article
Drug and bioactive molecule screening based on a bioelectrical impedance cell culture platform
Sakthivel Ramasamy, Devasier Bennet & Sanghyo Kim
Pages: 5789-5809
Published online: 10 Dec 2014
AbstractforDrug and bioactive molecule screening based on a bioelectrical impedance cell culture platform | Full Text | References | PDF (1.1 MB)
  • 157 Views
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Article
Effects of PEGylation on the physicochemical properties and in vivo distribution of organic nanotubes
Wuxiao Ding, Hiroyuki Minamikawa, Naohiro Kameta, Toshimi Shimizu & Mitsutoshi Masuda
Pages: 5811-5823
Published online: 12 Dec 2014
AbstractforEffects of PEGylation on the physicochemical properties and in vivo distribution of organic nanotubes | Full Text | References | PDF (6.6 MB)
  • 59 Views
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Review

Review Article
Chemical modulation of M13 bacteriophage and its functional opportunities for nanomedicine
Woo-Jae Chung, Doe-Young Lee & So Young Yoo
Pages: 5825-5836
Published online: 12 Dec 2014
AbstractforChemical modulation of M13 bacteriophage and its functional opportunities for nanomedicine | Full Text | References | PDF (1.9 MB)
  • 190 Views
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Article
Reprogramming fibroblasts to pluripotency using arginine-terminated polyamidoamine nanoparticles based non-viral gene delivery system
Kai Zhu, Jun Li, Hao Lai, Cheng Yang, Changfa Guo & Chunsheng Wang
Pages: 5837-5847
Published online: 12 Dec 2014
AbstractforReprogramming fibroblasts to pluripotency using arginine-terminated polyamidoamine nanoparticles based non-viral gene delivery system | Full Text | References | PDF (11.4 MB)
  • 70 Views
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Article
Self-assembled micelles of amphiphilic poly(l-phenylalanine)-b-poly(l-serine) polypeptides for tumor-targeted delivery
Ziming Zhao, Yu Wang, Jin Han, Keli Wang, Dan Yang, Yihua Yang, Qian Du, Yuanjian Song & Xiaoxing Yin
Pages: 5849-5862
Published online: 12 Dec 2014
AbstractforSelf-assembled micelles of amphiphilic poly(l-phenylalanine)-b-poly(l-serine) polypeptides for tumor-targeted delivery | Full Text | References | PDF (3 MB)
  • 95 Views
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