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International Journal of Nanomedicine Volume 10, 2015 - Issue
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Original Research

Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors

Huali Wu1 UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA
,
Jeffrey R Infante2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
,
Vicki L Keedy3 Vanderbilt University, Nashville, TN, USA
,
Suzanne F Jones2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
,
Emily Chan3 Vanderbilt University, Nashville, TN, USA
,
Johanna C Bendell2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
,
Wooin Lee4 Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY, USA
,
Whitney P Kirschbrown1 UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA
,
Beth A Zamboni5 Department of Mathematics, Carlow University, Pittsburgh, PA, USA
,
Satoshi Ikeda6 Yakult Honsha Co., Ltd., Medical Development Department, Tokyo, Japan
,
Hiroshi Kodaira6 Yakult Honsha Co., Ltd., Medical Development Department, Tokyo, Japan
,
Mace L Rothenberg3 Vanderbilt University, Nashville, TN, USA
,
Howard A Burris III2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
&
William C Zamboni1 UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA;7 UNC Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA;8 UNC Institute for Pharmacogenomics and Individualized Therapy, University of North Carolina, Chapel Hill, NC, USA;9 Carolina Center for Cancer Nanotechology Excellence, University of North Carolina, Chapel Hill, NC, USACorrespondence[email protected]
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Pages 1201-1209 | Published online: 10 Feb 2015

Citations (12)

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Di Wang, Yating Sun, Yange Liu, Fanchao Meng & Robert J. Lee. (2018) Clinical translation of immunoliposomes for cancer therapy: recent perspectives. Expert Opinion on Drug Delivery 15:9, pages 893-903.
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Articles from other publishers (11)

Seth Kwabena Amponsah & Ismaila Adams. 2022. Nanocarriers for Drug-Targeting Brain Tumors. Nanocarriers for Drug-Targeting Brain Tumors 121 141 .
Aaishwarya Deshmukh, Jayvadan K. Patel & Yashwant V. Pathak. 2022. Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems. Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems 79 100 .
Guohua Liang, Wenjie Ma, Yanfang Zhao, Eryu Liu, Xiaoyu Shan, Weiwei Ma, Dabei Tang, Liru Li, Xingjian Niu, Wenhui Zhao & Qingyuan Zhang. (2021) Risk factors for pegylated liposomal doxorubicin-induced moderate to severe hand-foot syndrome in breast cancer patients: assessment of baseline clinical parameters. BMC Cancer 21:1.
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Iara Maíra de Oliveira Viana, Sabrina Roussel, Joan Defrêne, Eliana Martins Lima, Frédéric Barabé & Nicolas Bertrand. (2021) Innate and adaptive immune responses toward nanomedicines. Acta Pharmaceutica Sinica B 11:4, pages 852-870.
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Hua He, Dongfen Yuan, Yun Wu & Yanguang Cao. (2019) Pharmacokinetics and Pharmacodynamics Modeling and Simulation Systems to Support the Development and Regulation of Liposomal Drugs. Pharmaceutics 11:3, pages 110.
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Brittney R. Starling, Parag Kumar, Andrew T. Lucas, David Barrow, Laura Farnan, Laura Hendrix, Hugh Giovinazzo, Gina Song, Paola Gehrig, Jeannette T. Bensen & William C. Zamboni. (2018) Mononuclear phagocyte system function and nanoparticle pharmacology in obese and normal weight ovarian and endometrial cancer patients. Cancer Chemotherapy and Pharmacology 83:1, pages 61-70.
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Anne Rodallec, Sebastien Benzekry, Bruno Lacarelle, Joseph Ciccolini & Raphaelle Fanciullino. (2018) Pharmacokinetics variability: Why nanoparticles are not just magic-bullets in oncology. Critical Reviews in Oncology/Hematology 129, pages 1-12.
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James D. Byrne, Mohammad R. N. Jajja, Adrian T. O’Neill, Allison N. Schorzman, Amanda W. Keeler, J. Christopher Luft, William C. Zamboni, Joseph M. DeSimone & Jen Jen Yeh. (2018) Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer. Cancer Chemotherapy and Pharmacology 81:6, pages 991-998.
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Ana Filipa Cruz, Nuno A. Fonseca, Ana C. Gregório, Vera Moura, Sérgio Simões & João Nuno Moreira. 2018. Particles and Nanoparticles in Pharmaceutical Products. Particles and Nanoparticles in Pharmaceutical Products 171 211 .
Danial E. Baker & Terri L. Levien. (2017) Irinotecan Liposome Injection. Hospital Pharmacy 52:2, pages 144-150.
Crossref
James D. ByrneMohammad R. N. JajjaAllison N. SchorzmanAmanda W. KeelerJ. Christopher LuftWilliam C. ZamboniJoseph M. DeSimoneJen Jen Yeh. (2016) Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma. Proceedings of the National Academy of Sciences 113:8, pages 2200-2205.
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