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Original Research
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors
Huali Wu1 UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA
, Jeffrey R Infante2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
, Vicki L Keedy3 Vanderbilt University, Nashville, TN, USA
, Suzanne F Jones2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
, Emily Chan3 Vanderbilt University, Nashville, TN, USA
, Johanna C Bendell2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
, Wooin Lee4 Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY, USA
, Whitney P Kirschbrown1 UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA
, Beth A Zamboni5 Department of Mathematics, Carlow University, Pittsburgh, PA, USA
, Satoshi Ikeda6 Yakult Honsha Co., Ltd., Medical Development Department, Tokyo, Japan
, Hiroshi Kodaira6 Yakult Honsha Co., Ltd., Medical Development Department, Tokyo, Japan
, Mace L Rothenberg3 Vanderbilt University, Nashville, TN, USA
, Howard A Burris III2 Sarah Cannon Research Institute/Tennessee Oncology, PLLC, USA
& William C Zamboni1 UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA;7 UNC Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA;8 UNC Institute for Pharmacogenomics and Individualized Therapy, University of North Carolina, Chapel Hill, NC, USA;9 Carolina Center for Cancer Nanotechology Excellence, University of North Carolina, Chapel Hill, NC, USACorrespondence[email protected]
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Pages 1201-1209
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Published online: 10 Feb 2015
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