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International Journal of Nanomedicine Volume 10, 2015 - Issue
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Original Research

Efficient delivery of ursolic acid by poly(N-vinylpyrrolidone)-block-poly (ε-caprolactone) nanoparticles for inhibiting the growth of hepatocellular carcinoma in vitro and in vivo

Hao Zhang1 Department of Geriatric Gastroenterology, First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China
,
Donghui Zheng2 Department of Nephrology, Huai’an Hospital Affiliated with Xuzhou Medical College and Huai’an Second Hospital, Huai’an, People’s Republic of China
,
Jing Ding3 Department of Respiratory Medicine, Affiliated Nanjing Children Hospital with Nanjing Medical University, Nanjing, People’s Republic of China
,
Huae Xu4 Department of Pharmacy, First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China
,
Xiaolin Li1 Department of Geriatric Gastroenterology, First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China
&
Weihao Sun1 Department of Geriatric Gastroenterology, First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
Pages 1909-1920 | Published online: 11 Mar 2015

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Mahfoozur Rahman, Waleed H Almalki, Majed Alrobaian, Jawed Iqbal, Saad Alghamdi, Khalid S Alharbi, Nabil K Alruwaili, Abdul Hafeez, Adil Shaharyar, Tanuja Singh, Mohammad Waris, Vikas Kumar & Sarwar Beg. (2021) Nanocarriers-loaded with natural actives as newer therapeutic interventions for treatment of hepatocellular carcinoma. Expert Opinion on Drug Delivery 18:4, pages 489-513.
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Sayan Biswas, Amit Kar, Nanaocha Sharma, Pallab K. Haldar & Pulok K. Mukherjee. (2021) Synergistic effect of ursolic acid and piperine in CCl4 induced hepatotoxicity. Annals of Medicine 53:1, pages 2009-2017.
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Zhe Han, Qi Yan, Wei Ge, Zhi-Guo Liu, Sangiliyandi Gurunathan, Massimo De Felici, Wei Shen & Xi-Feng Zhang. (2016) Cytotoxic effects of ZnO nanoparticles on mouse testicular cells. International Journal of Nanomedicine 11, pages 5187-5203.
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Qiuxia Huang, Hongfei Chen, Yuyan Ren, Zhe Wang, Peiyu Zeng, Xuan Li, Juan Wang & Xing Zheng. (2016) Anti-hepatocellular carcinoma activity and mechanism of chemopreventive compounds: ursolic acid derivatives. Pharmaceutical Biology 54:12, pages 3189-3196.
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Articles from other publishers (9)

Aristote Buya. 2023. Advances in Novel Formulations for Drug Delivery. Advances in Novel Formulations for Drug Delivery 97 125 .
Andang Miatmoko, Ester Adelia Mianing, Retno Sari & Esti Hendradi. (2021) Nanoparticles use for Delivering Ursolic Acid in Cancer Therapy: A Scoping Review. Frontiers in Pharmacology 12.
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Manoja K. Brahma, Eduardo H. Gilglioni, Lang Zhou, Eric Trépo, Pengyu Chen & Esteban N. Gurzov. (2021) Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges. Oncogene 40:33, pages 5155-5167.
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Longyun Wang, Qianqian Yin, Cun Liu, Ying Tang, Changgang Sun & Jing Zhuang. (2021) Nanoformulations of Ursolic Acid: A Modern Natural Anticancer Molecule. Frontiers in Pharmacology 12.
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Anna Kaps, Paweł Gwiazdoń & Ewa Chodurek. (2021) Nanoformulations for Delivery of Pentacyclic Triterpenoids in Anticancer Therapies. Molecules 26:6, pages 1764.
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Gillian E. Conway, Deimante Zizyte, Julie Rose Mae Mondala, Zhonglei He, Lorna Lynam, Mathilde Lecourt, Carlos Barcia, Orla Howe & James F. Curtin. (2021) Ursolic Acid Inhibits Collective Cell Migration and Promotes JNK-Dependent Lysosomal Associated Cell Death in Glioblastoma Multiforme Cells. Pharmaceuticals 14:2, pages 91.
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Saber Ghazizadeh DarbandEhsan SabooryShirin SadighparvarMojtaba KavianiKazhal MobarakiNasrollah JabbariMaryam Majidinia. (2020) The modulatory effects of exercise on the inflammatory and apoptotic markers in rats with 1,2-dimethylhydrazine-induced colorectal cancer. Canadian Journal of Physiology and Pharmacology 98:3, pages 147-155.
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Prasant Nahak, Gourab Karmakar, Priyam Chettri, Biplab Roy, Pritam Guha, Shila Elizabeth Besra, Anjana Soren, Alexey G. Bykov, Alexander V. Akentiev, Boris A. Noskov & Amiya Kumar Panda. (2016) Influence of Lipid Core Material on Physicochemical Characteristics of an Ursolic Acid-Loaded Nanostructured Lipid Carrier: An Attempt To Enhance Anticancer Activity. Langmuir 32:38, pages 9816-9825.
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Hui Zhou, Xiaoxing Liu, Fenglei Wu, Junting Zhang, Zhen Wu, Haitao Yin & Hui Shi. (2016) Preparation, Characterization, and Antitumor Evaluation of Electrospun Resveratrol Loaded Nanofibers. Journal of Nanomaterials 2016, pages 1-11.
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