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Original Research

Enhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo

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Pages 6633-6644 | Published online: 22 Oct 2015

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Rania F. Ahmed, Maha Nasr, Marawan Abd Elbaset, Alyaa Farouk Hessin, Omar A. H. Ahmed-Farid, Nermeen M. Shaffie & Marwa E. Shabana. (2022) Combating hematopoietic and hepatocellular abnormalities resulting from administration of cisplatin: role of liver targeted glycyrrhetinic acid nanoliposomes loaded with amino acids. Pharmaceutical Development and Technology 27:9, pages 925-941.
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Ailing Zhang, Jianbo Li, Shuaishuai Wang, Yaru Xu, Qinglian Li, Zhe Wu, Chenxu Wang, Haiyang Meng & Jinjie Zhang. (2021) Rapid and improved oral absorption of N-butylphthalide by sodium cholate-appended liposomes for efficient ischemic stroke therapy. Drug Delivery 28:1, pages 2469-2479.
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Bing Chen, Xuewen Wang, Dan Lin, Dafen Xu, Shaoguang Li, Jianyong Huang, Shaohuang Weng, Zhen Lin, Yanjie Zheng, Hong Yao & Xinhua Lin. (2019) Proliposomes for oral delivery of total biflavonoids extract from Selaginella doederleinii: formulation development, optimization, and in vitro–in vivo characterization. International Journal of Nanomedicine 14, pages 6691-6706.
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Gang Yang, Feihua Wu, Minyan Chen, Jian Jin, Rong Wang & Yongfang Yuan. (2019) Formulation design, characterization, and in vitro and in vivo evaluation of nanostructured lipid carriers containing a bile salt for oral delivery of gypenosides. International Journal of Nanomedicine 14, pages 2267-2280.
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Ranjith Kumar Kankala, Biao-Qi Chen, Chen-Guang Liu, Han-Xiao Tang, Shi-Bin Wang & Ai-Zheng Chen. (2018) Solution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds. International Journal of Nanomedicine 13, pages 4227-4245.
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Abdul Ahad, Mohammad Raish, Ajaz Ahmad, Fahad I. Al-Jenoobi & Abdullah M. Al-Mohizea. (2018) Development and biological evaluation of vesicles containing bile salt of telmisartan for the treatment of diabetic nephropathy. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 532-539.
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Carola Diaz, José Guzmán, Verónica A. Jiménez & Joel B. Alderete. (2018) Partially PEGylated PAMAM dendrimers as solubility enhancers of Silybin. Pharmaceutical Development and Technology 23:7, pages 689-696.
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Jin Ren, Zhengjie Fang, Liqun Jiang & Qian Du. (2017) Quercetin-containing self-assemble proliposome preparation and evaluation. Journal of Liposome Research 27:4, pages 335-342.
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