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Journal of Asthma and Allergy Volume 8, 2015 - Issue
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Review

The past, present, and future of monoclonal antibodies to IL-5 and eosinophilic asthma: a review

Megan F Patterson1 Department of Pediatrics, Arkansas Children’s Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA
,
Larry Borish2 Department of Medicine, Carter Immunology Center, University of Virginia Health Systems, Charlottesville, VA, USA;3 Department of Microbiology, Carter Immunology Center, University of Virginia Health Systems, Charlottesville, VA, USA
&
Joshua L Kennedy1 Department of Pediatrics, Arkansas Children’s Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA;4 Department of Internal Medicine, Arkansas Children’s Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USACorrespondence[email protected]
Pages 125-134 | Published online: 03 Nov 2015

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Corrado Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Rosa Terracciano, Rocco Savino & Girolamo Pelaia. (2017) Severe eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab. Drug Design, Development and Therapy 11, pages 3137-3144.
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Mitchell Goldman, Ian Hirsch, James G. Zangrilli, Paul Newbold & Xiao Xu. (2017) The association between blood eosinophil count and benralizumab efficacy for patients with severe, uncontrolled asthma: subanalyses of the Phase III SIROCCO and CALIMA studies. Current Medical Research and Opinion 33:9, pages 1605-1613.
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Girolamo Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Mariaimmacolata Preianò, Nicola Lombardo, Rosa Terracciano & Rosario Maselli. (2016) Role of biologics in severe eosinophilic asthma – focus on reslizumab. Therapeutics and Clinical Risk Management 12, pages 1075-1082.
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Articles from other publishers (6)

Beatriz León & Andre Ballesteros-Tato. (2021) Modulating Th2 Cell Immunity for the Treatment of Asthma. Frontiers in Immunology 12.
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Adam S. Price & Joshua L. Kennedy. 2021. Encyclopedia of Molecular Pharmacology. Encyclopedia of Molecular Pharmacology 865 872 .
Adam S. Price & Joshua L. Kennedy. 2020. Encyclopedia of Molecular Pharmacology. Encyclopedia of Molecular Pharmacology 1 8 .
Genny Chaia, Ubaldo Martín, Arturo Cortés-Telles, Fernando Morett, José Julio Gutiérrez-Mujica, Adriana Zepeda-Gómez, Alberto Hegewisch & Rogelio Ramses Hernández. (2020) Benralizumab: eficacia y seguridad en pacientes con asma grave eosinofílica.. Revista Alergia México 67.
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Jörg D. Leuppi, Peter Schmid-Grendelmeier, Thomas Rothe, Christophe von Garnier, Hans-Uwe Simon, Claudio Schuoler, Gunther Pendl & Markus Solèr. (2019) Benralizumab: Cibler le récepteur de l’IL-5 dans l’asthme sévère éosinophile. Praxis 108:7, pages 1-8.
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Jörg D. Leuppi, Peter Schmid-Grendelmeier, Thomas Rothe, Christophe von Garnier, Hans-Uwe Simon, Claudio Schuoler, Gunther Pendl & Markus Solèr. (2019) Benralizumab: Der IL-5-Rezeptor als Ziel bei schwerem eosinophilem Asthma. Praxis 108:7, pages 469-476.
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