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Experimental GABA A Receptor Agonists and Allosteric Modulators for the Treatment of Focal Epilepsy

Slobodan M Janković1 Faculty of Medical Sciences, University of Kragujevac, Kragujevac, SerbiaCorrespondence[email protected]

https://orcid.org/0000-0002-1519-8828

Miralem Dješević2 Cardiology Department, Private Policlinic Center Eurofarm, Sarajevo, Bosnia and Hercegovina

Snežana V Janković1 Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia

Pages 235-244 | Published online: 08 Mar 2021

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Tingting Hu, Jifa Zhang, Jiaxing Wang, Leihao Sha, Yilin Xia, Tyler C. Ortyl, Xiaohe Tian & Lei Chen. (2023) Advances in Epilepsy: Mechanisms, Clinical Trials, and Drug Therapies. Journal of Medicinal Chemistry 66:7, pages 4434-4467.
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Wolfgang Löscher. (2023) Is the antiparasitic drug ivermectin a suitable candidate for the treatment of epilepsy?. Epilepsia 64:3, pages 553-566.
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Manuela Gernert, Devlin MacKeigan, Lillian Deking, Edith Kaczmarek & Malte Feja. (2023) Acute and chronic convection-enhanced muscimol delivery into the rat subthalamic nucleus induces antiseizure effects associated with high responder rates. Epilepsy Research 190, pages 107097.
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Nan Wu, Tao Sun, Xin Wu, Hongguang Chen & Zhen Zhang. (2023) Modulation of GABAB receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks. Frontiers in Behavioral Neuroscience 16.
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Ung Gu Kang, Se Hyun Kim, Nam Young Lee, Kyu Young Lee, Yong Sik Kim & In Won Chung. (2023) Benzodiazepines: Pharmacology Up-to-Date and Practical Issues. Journal of Korean Neuropsychiatric Association 62:1, pages 1.
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Jiakang Liu & Tianxing Shao. (2022) Genetic Mutations That Lead to Ohtahara Syndrome and Childhood Absence Epilepsy. Highlights in Science, Engineering and Technology 8, pages 152-162.
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Rok Cerne, Arnold Lippa, Michael M. Poe, Jodi L. Smith, Xiaoming Jin, Xingjie Ping, Lalit K. Golani, James M. Cook & Jeffrey M. Witkin. (2022) GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors. Pharmacology & Therapeutics 234, pages 108035.
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Inah Camaya, Sheila Donnelly & Bronwyn O'Brien. (2022) Targeting the PI3K /Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes . Journal of Diabetes 14:4, pages 247-260.
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Eva Kudova, Pavel Mares, Martin Hill, Katerina Vondrakova, Grygoriy Tsenov, Hana Chodounska, Hana Kubova & Karel Vales. (2021) The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains. Pharmaceuticals 15:1, pages 49.
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Amr Ghit, Dina Assal, Ahmed S. Al-Shami & Diaa Eldin E. Hussein. (2021) GABAA receptors: structure, function, pharmacology, and related disorders. Journal of Genetic Engineering and Biotechnology 19:1.
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Yuya Sakimoto, Paw Min-Thein Oo, Makoto Goshima, Itsuki Kanehisa, Yutaro Tsukada & Dai Mitsushima. (2021) Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology. International Journal of Molecular Sciences 22:22, pages 12456.
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Experimental GABA A Receptor Agonists and Allosteric Modulators for the Treatment of Focal Epilepsy

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Experimental GABA A Receptor Agonists and Allosteric Modulators for the Treatment of Focal Epilepsy

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