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Journal of Inflammation Research Volume 14, 2021 - Issue
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Original Research

Generation and Characterization of Torudokimab (LY3375880): A Monoclonal Antibody That Neutralizes Interleukin-33

Angela J Okragly1 Immunology Research, Eli Lilly and Company, Indianapolis, IN, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1041-8000View further author information
ORCID Icon,
Katie Brannon Corwin2 BioTechnology Discovery Research, Eli Lilly and Company, Indianapolis, IN, USAORCID Iconhttps://orcid.org/0000-0002-3082-9325View further author information
ORCID Icon,
Marikka Elia3 BioTechnology Discovery Research Eli Lilly and Company, San Diego, CA, USAORCID Iconhttps://orcid.org/0000-0002-4224-0761View further author information
ORCID Icon,
Dongmei He3 BioTechnology Discovery Research Eli Lilly and Company, San Diego, CA, USAView further author information
,
Oliver Schroeder3 BioTechnology Discovery Research Eli Lilly and Company, San Diego, CA, USAView further author information
,
Qing Zhang3 BioTechnology Discovery Research Eli Lilly and Company, San Diego, CA, USAView further author information
,
Tatiyana Shiyanova2 BioTechnology Discovery Research, Eli Lilly and Company, Indianapolis, IN, USAORCID Iconhttps://orcid.org/0000-0002-9320-2933View further author information
ORCID Icon,
Stuart Bright1 Immunology Research, Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
Sarah B Dicker4 ADME, Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
Lukasz Chlewicki4 ADME, Eli Lilly and Company, Indianapolis, IN, USAView further author information
,
Stephanie M E Truhlar3 BioTechnology Discovery Research Eli Lilly and Company, San Diego, CA, USAView further author information
,
Julian Davies3 BioTechnology Discovery Research Eli Lilly and Company, San Diego, CA, USAORCID Iconhttps://orcid.org/0000-0002-1715-3463View further author information
ORCID Icon,
Chetan N Patel2 BioTechnology Discovery Research, Eli Lilly and Company, Indianapolis, IN, USAView further author information
&
Robert J Benschop1 Immunology Research, Eli Lilly and Company, Indianapolis, IN, USAORCID Iconhttps://orcid.org/0000-0001-6313-5218View further author information
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Pages 3823-3835 | Published online: 11 Aug 2021

Citations (3)

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Read on this site (1)

Rohit Gaurav & Jill A. Poole. (2022) Interleukin (IL)-33 immunobiology in asthma and airway inflammatory diseases. Journal of Asthma 59:12, pages 2530-2538.
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Articles from other publishers (2)

Elizabeth England, D. Gareth Rees, Ian Christopher Scott, Sara Carmen, Denice T. Y. Chan, Catherine E. Chaillan Huntington, Kirsty F. Houslay, Teodor Erngren, Mark Penney, Jayesh B. Majithiya, Laura Rapley, Dorothy A. Sims, Claire Hollins, Elizabeth C. Hinchy, Martin D. Strain, Benjamin P. Kemp, Dominic J. Corkill, Richard D. May, Katherine A. Vousden, Robin J. Butler, Tomas Mustelin, Tristan J. Vaughan, David C. Lowe, Caroline Colley & E. Suzanne Cohen. (2023) Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction. Scientific Reports 13:1.
Crossref
Eden David, Benjamin Ungar, Yael Renert‐Yuval, Paola Facheris, Ester del Duca & Emma Guttman‐Yassky. (2023) The evolving landscape of biologic therapies for atopic dermatitis: Present and future perspective. Clinical & Experimental Allergy 53:2, pages 156-172.
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