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Journal of Inflammation Research Volume 14, 2021 - Issue
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Original Research

Effectiveness of Tocilizumab with and without Dexamethasone in Patients with Severe COVID-19: A Retrospective Study

Dorota Zarębska-Michaluk1 Department of Infectious Diseases, Jan Kochanowski University, Kielce, 25-369, PolandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0938-1084View further author information
ORCID Icon,
Jerzy Jaroszewicz2 Department of Infectious Diseases and Hepatology, Medical University of Silesia, Katowice, 40-055, PolandView further author information
,
Magdalena Rogalska3 Department of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, 15-089, PolandView further author information
,
Diana Martonik3 Department of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, 15-089, PolandView further author information
,
Paweł Pabjan1 Department of Infectious Diseases, Jan Kochanowski University, Kielce, 25-369, PolandORCID Iconhttps://orcid.org/0000-0002-7682-1185View further author information
ORCID Icon,
Aleksandra Berkan-Kawińska4 Department of Infectious Diseases and Hepatology, Medical University of Łódź, Łódź, 90-549, PolandView further author information
,
Beata Bolewska5 Department of Infectious Diseases, University of Medical Sciences, Poznań, 61-701, PolandView further author information
,
Barbara Oczko-Grzesik2 Department of Infectious Diseases and Hepatology, Medical University of Silesia, Katowice, 40-055, PolandView further author information
,
Dorota Kozielewicz6 Department of Infectious Diseases and Hepatology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, 87-100, PolandView further author information
,
Magdalena Tudrujek-Zdunek7 Department of Infectious Diseases and Hepatology, Medical University of Lublin, Lublin, 20-059, PolandView further author information
,
Justyna Kowalska8 Department of Adults’ Infectious Diseases, Medical University of Warsaw, Warsaw, 02-091, PolandView further author information
,
Anna Moniuszko-Malinowska9 Department of Infectious Diseases and Neuroinfections, Medical University of Białystok, Białystok, 15-089, PolandView further author information
,
Krzysztof Kłos10 Department of Infectious Diseases and Allergology, Military Institute of Medicine, Warsaw, 04-141, PolandORCID Iconhttps://orcid.org/0000-0001-9629-5680View further author information
ORCID Icon,
Marta Rorat11 Department of Forensic Medicine, Wrocław Medical University, Wrocław, 50-367, Poland;12 First Infectious Diseases Ward, Gromkowski Regional Specialist Hospital in Wrocław, Wrocław, 51-149, PolandView further author information
,
Piotr Leszczyński13 Department of Rheumatology, Rehabilitation and Internal Medicine, Poznan University of Medical Sciences, Poznań, 61-701, Poland;14 Department of Rheumatology and Osteoporosis, Szpital im. J. Strusia w Poznaniu, Poznań, 61-285, PolandView further author information
,
Anna Piekarska4 Department of Infectious Diseases and Hepatology, Medical University of Łódź, Łódź, 90-549, PolandView further author information
,
Joanna Polańska15 Silesian University of Technology, Gliwice, 44-100, PolandORCID Iconhttps://orcid.org/0000-0001-8004-9864View further author information
ORCID Icon &
Robert Flisiak3 Department of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, 15-089, PolandView further author information
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Pages 3359-3366 | Published online: 16 Jul 2021

Citations (13)

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Yu Cao, Ying Han, Jiangping Wu, Jianping Sun, Yanchao Dai, Guifang Qiao, Kang Li, Ang Li, Yonghong Zhang, Yingmin Ma & Qingkun Song. (2023) During the Omicron Pandemic Wave, the Severe Systemic Inflammatory Status of COVID-19 Indicated a Higher Risk of In-Hospital Mortality and Mediated the Clinical Efficacy of Corticosteroids. Infection and Drug Resistance 16, pages 7377-7387.
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Robert Flisiak, Marta Flisiak-Jackiewicz, Piotr Rzymski & Dorota Zarębska-Michaluk. (2023) Tocilizumab for the treatment of COVID-19. Expert Review of Anti-infective Therapy 21:8, pages 791-797.
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Articles from other publishers (11)

Mardheya Al. Kharusi, Naffesa Al Sheikh, Maiya Alhajri, Seif Ali Al. Mandhri, El-Sayed Khafagy, Ehssan H. Moglad, Hadil Faris Alotaibi & Wael A. H. Hegazy. (2023) A Prospective Cohort Study of COVID-19: Evaluation of the Early Role of IL-1 and IL-6 Antagonists in Improving the Outcome of the Illness and Reduction in the Risk of Death. Healthcare 11:7, pages 1025.
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Justyna D. Kowalska, Martyna Lara, Maria Hlebowicz, Elżbieta Mularska, Elżbieta Jabłonowska, Ewa Siwak, Alicja Wandałowicz, Magdalena Witak-Jędra, Anita Olczak, Monika Bociąga-Jasik, Magdalena Suchacz, Justyna Stempkowska-Rejek, Piotr Wasilewski & Miłosz Parczewski. (2022) Non-HIV-related comorbidities and uncontrolled HIV replication are independent factors increasing the odds of hospitalization due to COVID-19 among HIV-positive patients in Poland. Infection 51:2, pages 379-387.
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Krystyna Dobrowolska, Dorota Zarębska-Michaluk, Michał Brzdęk, Piotr Rzymski, Magdalena Rogalska, Anna Moniuszko-Malinowska, Dorota Kozielewicz, Marcin Hawro, Marta Rorat, Katarzyna Sikorska, Jerzy Jaroszewicz, Justyna Kowalska & Robert Flisiak. (2023) Retrospective Analysis of the Effectiveness of Remdesivir in COVID-19 Treatment during Periods Dominated by Delta and Omicron SARS-CoV-2 Variants in Clinical Settings. Journal of Clinical Medicine 12:6, pages 2371.
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Tomasz Wojciech Rutkowski, Jerzy Jaroszewicz, Damian Piotrowski, Krzysztof Ślosarek, Barbara Sobala-Szczygieł, Dorota Słonina, Bożena Włostowska, Dawid Bodusz, Maciej Piasecki, Michał Nachlik, Barbara Oczko-Grzesik, Adam Gądek, Dorota Kowal, Roman Rutkowski, Elżbieta Wojarska-Tręda & Krzysztof Składowski. (2023) Low-Dose Radiotherapy for Patients with Pneumonia Due to COVID-19: A Single-Institution Prospective Study. Biomedicines 11:3, pages 858.
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Robert Flisiak, Piotr Rzymski, Dorota Zarębska-Michaluk, Przemysław Ciechanowski, Krystyna Dobrowolska, Magdalena Rogalska, Jerzy Jaroszewicz, Anna Szymanek-Pasternak, Marta Rorat, Dorota Kozielewicz, Justyna Kowalska, Ewa Dutkiewicz, Katarzyna Sikorska & Anna Moniuszko-Malinowska. (2023) Variability in the Clinical Course of COVID-19 in a Retrospective Analysis of a Large Real-World Database. Viruses 15:1, pages 149.
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Carlo Bieńkowski, Justyna D. Kowalska, Marcin Paciorek, Piotr Wasilewski, Paweł Uliczny, Ewelina Garbacz-Łagożna, Andrzej Pihowicz, Monika Mrozińska, Tomasz Dyda, Michał Makowiecki, Joanna Puła & Andrzej Horban. (2022) The Clinical Course and Outcomes of Patients Hospitalized Due to COVID-19 during Three Pandemic Waves in Poland: A Single Center Observational Study. Journal of Clinical Medicine 11:24, pages 7386.
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Robert Flisiak, Dorota Zarębska-Michaluk, Magdalena Rogalska, Justyna Anna Kryńska, Justyna Kowalska, Ewa Dutkiewicz, Krystyna Dobrowolska, Jerzy Jaroszewicz, Anna Moniuszko-Malinowska, Marta Rorat, Regina Podlasin, Olga Tronina & Piotr Rzymski. (2022) Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance. Pharmacological Reports 74:6, pages 1279-1285.
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Laila Rahmah, Sunny O. Abarikwu, Amanuel Godana Arero, Mickael Essouma, Aliyu Tijani Jibril, Andrzej Fal, Robert Flisiak, Rangarirai Makuku, Leander Marquez, Kawthar Mohamed, Lamin Ndow, Dorota Zarębska-Michaluk, Nima Rezaei & Piotr Rzymski. (2022) Oral antiviral treatments for COVID-19: opportunities and challenges. Pharmacological Reports 74:6, pages 1255-1278.
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Przemysław Holko & Paweł Kawalec. (2022) Wykorzystanie baz danych Narodowego Funduszu Zdrowia przy ocenie dowodów naukowych z praktyki klinicznej. Zdrowie Publiczne i Zarządzanie 20:2, pages 25-33.
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R. Ouissa, C. Le Guillou, M. Broudic, S. Markowicz, E. Curlier & P.-M. Roger. (2022) Successful high flow nasal cannula therapy for severe COVID-19 pneumonia is associated with tocilizumab use. Infectious Diseases Now 52:3, pages 145-148.
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Edda Russo, Lavinia Curini, Alessio Fabbrizzi & Amedeo Amedei. 2022. Microbiome in Inflammatory Lung Diseases. Microbiome in Inflammatory Lung Diseases 241 280 .

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