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Journal of Inflammation Research Volume 14, 2021 - Issue
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Original Research

The Flavonoid Kurarinone Regulates Macrophage Functions via Aryl Hydrocarbon Receptor and Alleviates Intestinal Inflammation in Irritable Bowel Syndrome

Xiang Xu1 Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaView further author information
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Qiwei Dong1 Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaView further author information
,
Qingling Zhong2 Department of Gastroenterology and Hepatology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaView further author information
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Wenbo Xiu1 Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China;2 Department of Gastroenterology and Hepatology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaView further author information
,
Qinyuan Chen1 Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China;2 Department of Gastroenterology and Hepatology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaView further author information
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Jinxia Wang1 Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaView further author information
&
Zhou Zhou1 Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China;2 Department of Gastroenterology and Hepatology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of ChinaCorrespondence[email protected]
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Pages 4347-4359 | Published online: 03 Sep 2021

Citations (12)

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Andrea Shin & Purna C. Kashyap. (2023) Multi-omics for biomarker approaches in the diagnostic evaluation and management of abdominal pain and irritable bowel syndrome: what lies ahead. Gut Microbes 15:1.
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Articles from other publishers (11)

Mei-Lan Tsai, Shih-Hsien Hsu, Li-Ting Wang, Wei-Ting Liao, Yi-Ching Lin, Chang-Hung Kuo, Ya-Ling Hsu, Ming-Chu Feng, Fu-Chen Kuo & Chih-Hsing Hung. (2023) Di(2-ethylhexyl) phthalate mediates IL-33 production via aryl hydrocarbon receptor and is associated with childhood allergy development. Frontiers in Immunology 14.
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Sarah F. Andres, Yang Zhang, Madeline Kuhn & Brian Scottoline. (2023) Building better barriers: how nutrition and undernutrition impact pediatric intestinal health. Frontiers in Immunology 14.
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Ling Yang, Chen Zheng, Yu-Feng Xia, Yue Dai & Zhi-Feng Wei. (2023) 3, 3’-diindolylmethane enhances macrophage efferocytosis and subsequently relieves visceral pain via the AhR/Nrf2/Arg-1-mediated arginine metabolism pathway. Phytomedicine 116, pages 154874.
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Yue Chen, Yadong Wang, Yawei Fu, Yulong Yin & Kang Xu. (2023) Modulating AHR function offers exciting therapeutic potential in gut immunity and inflammation. Cell & Bioscience 13:1.
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Bin Liu, Ding Ye, Hong Yang, Jie Song, Xiaohui Sun, Zhixing He, Yingying Mao & Guifeng Hao. (2023) Assessing the relationship between gut microbiota and irritable bowel syndrome: a two-sample Mendelian randomization analysis. BMC Gastroenterology 23:1.
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Alessandra A. Filardy, Jesuino R.M. Ferreira, Rafael M. Rezende, Brian L. Kelsall & Rafael P. Oliveira. (2023) The intestinal microenvironment shapes macrophage and dendritic cell identity and function. Immunology Letters 253, pages 41-53.
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Qiang Lu, Daopeng Tan, Jingbin Luo, Yonghao Ye, Manhua Zuo, Siyu Wang & Cailan Li. (2022) Potential of natural products in the treatment of irritable bowel syndrome. Phytomedicine 106, pages 154419.
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Mengmeng Song, Xianjie Sheng, Jianrong Zhang, Xinru Li, Qianyun Dai, Yan Chen & An Kang. (2022) Homeostatic regulation of the aryl hydrocarbon receptor-cytochrome P450 1a axis by Scutellaria baicalensis-Coptis chinensis herb pair and its main constituents. Journal of Ethnopharmacology 297, pages 115545.
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Alice Sychrová, Gabriela Škovranová, Marie Čulenová & Silvia Bittner Fialová. (2022) Prenylated Flavonoids in Topical Infections and Wound Healing. Molecules 27:14, pages 4491.
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Lianyu Song, Xin Hu, Xiaomin Ren, Jing Liu & Xiaoye Liu. (2022) Antibacterial Modes of Herbal Flavonoids Combat Resistant Bacteria. Frontiers in Pharmacology 13.
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Xiang Xu, Gao Zhang, Kun Peng, Yanping Gao, Jinxia Wang, Caiping Gao, Chong He & Fang Lu. (2022) Carnosol Maintains Intestinal Barrier Function and Mucosal Immune Homeostasis in DSS-Induced Colitis. Frontiers in Nutrition 9.
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