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Review

Serotonin receptor agonists in the acute treatment of migraine: a review on their therapeutic potential

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Pages 515-526 | Published online: 08 Mar 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

William David Wells-Gatnik, Tiffany Yazmin Wences Chirino, Fatma Nur Onan, Dilara Onan & Paolo Martelletti. (2023) Emerging experimental drugs in clinical trials for migraine: observations and key talking points. Expert Opinion on Investigational Drugs 32:8, pages 761-771.
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Andrea Negro & Paolo Martelletti. (2021) Novel synthetic treatment options for migraine. Expert Opinion on Pharmacotherapy 22:7, pages 907-922.
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Martina Curto, Fabiola Cipolla, Giusy Ylenia Cisale, Matilde Capi, Valerio Spuntarelli, Martina Guglielmetti, Paolo Martelletti & Luana Lionetto. (2020) Profiling lasmiditan as a treatment option for migraine. Expert Opinion on Pharmacotherapy 21:2, pages 147-153.
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Andrea Negro & Paolo Martelletti. (2019) Patient selection for migraine preventive treatment with anti-CGRP(r) monoclonal antibodies. Expert Review of Neurotherapeutics 19:8, pages 769-776.
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Andrea Negro & Paolo Martelletti. (2019) Gepants for the treatment of migraine. Expert Opinion on Investigational Drugs 28:6, pages 555-567.
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Paolo Martelletti & Maria Adele Giamberardino. (2019) Advances in orally administered pharmacotherapy for the treatment of migraine. Expert Opinion on Pharmacotherapy 20:2, pages 209-218.
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Jessica C Oswald & Nathaniel M Schuster. (2018) Lasmiditan for the treatment of acute migraine: a review and potential role in clinical practice. Journal of Pain Research 11, pages 2221-2227.
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Cinder Faith Cohen, Jueun Roh, Sang Hoon Lee, Chul-Kyu Park & Temugin Berta. (2023) Targeting Nociceptive Neurons and Transient Receptor Potential Channels for the Treatment of Migraine. International Journal of Molecular Sciences 24:9, pages 7897.
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Surajpal Verma, Rajiv Kumar Tonk, Mohammed Albratty, Hassan Ahmad Alhazmi, Asim Najmi, Ravi Kumar, Mohit Kumar, Mohamad Taleuzzaman, Gourav Swami & Md Shamsher Alam. (2022) Design and evaluation of sustained release mucoadhesive film of sumatriptan succinate containing grafted co-polymer as the platform. Saudi Pharmaceutical Journal 30:11, pages 1527-1537.
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Ana Claudia Sueiro, Érica Mendes dos Santos, Louise Lacalendola Tundisi, Ana Laura Masquetti Fava, Luiza Aparecida Luna Silvério, Julia Cedran Coco, Janaína Artem Ataide, Ana Cláudia Paiva-Santos & Priscila Gava Mazzola. (2022) Transdermal delivery systems for migraine treatment: A gap to explore. Journal of Drug Delivery Science and Technology 77, pages 103919.
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Michael T. Li, Christopher Louis Robinson, Qing Zhao Ruan, Sindhuja Surapaneni & Warren Southerland. (2022) The Influence of Sleep Disturbance on Chronic Pain. Current Pain and Headache Reports 26:10, pages 795-804.
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Roger Gregory Biringer. (2022) Migraine signaling pathways: amino acid metabolites that regulate migraine and predispose migraineurs to headache. Molecular and Cellular Biochemistry 477:9, pages 2269-2296.
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Mahsa Pourhamzeh, Fahimeh Ghasemi Moravej, Mehrnoosh Arabi, Elahe Shahriari, Soraya Mehrabi, Richard Ward, Reza Ahadi & Mohammad Taghi Joghataei. (2021) The Roles of Serotonin in Neuropsychiatric Disorders. Cellular and Molecular Neurobiology 42:6, pages 1671-1692.
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John H. Krege, Richard B. Lipton, Simin K. Baygani, Mika Komori, Sinéad M. Ryan & Maurice Vincent. (2022) Lasmiditan for Patients with Migraine and Contraindications to Triptans: A Post Hoc Analysis. Pain and Therapy 11:2, pages 701-712.
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Alfredo Munoz, Christina Maxwell, Natalie Gofman, Kenneth Liebman & Erol Veznedaroglu. (2022) The management of trigeminal neuralgia with triptans, a narrative review of the literature. Headache: The Journal of Head and Face Pain 62:5, pages 543-547.
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Darko Katalinic, Aleksandar Vcev, Martina Smolic & Ivan Aleric. (2022) Serotonin receptor agonists in the treatment of migraine: A meta-analysis considering possible connection with paresthesia. Annals of Indian Academy of Neurology 25:3, pages 332.
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Oliver Clark, Areej Mahjoub, Nily Osman, Ann-Marie Surmava, Saber Jan & Ana Marissa Lagman-Bartolome. (2021) Non-invasive neuromodulation in the acute treatment of migraine: a systematic review and meta-analysis of randomized controlled trials. Neurological Sciences 43:1, pages 153-165.
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Eduardo Rivera-Mancilla & Antoinette MaassenVanDenBrink. 2022. Novel Synthetic Drugs in Migraine. Novel Synthetic Drugs in Migraine 1 17 .
Andrew Blumenfeld, Paul L. Durham, Alexander Feoktistov, Debbie L. Hay, Andrew F. Russo & Ira Turner. (2021) Hypervigilance, Allostatic Load, and Migraine Prevention: Antibodies to CGRP or Receptor. Neurology and Therapy 10:2, pages 469-497.
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Rituparna Maiti, Archana Mishra, Haridas Mundot Puliappadamb, Monalisa Jena & Anand Srinivasan. (2021) Efficacy and Safety of Lasmiditan for Acute Treatment of Migraine in Adults: A Meta‐Analysis. The Journal of Clinical Pharmacology 61:12, pages 1534-1544.
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Jae Hyun Lee, Anand R. Shewale, Douglas Barthold & Beth Devine. (2021) Geographic variation in the use of triptans and opioids for the acute treatment of migraine attacks. Headache: The Journal of Head and Face Pain 61:10, pages 1499-1510.
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Moein Ala, Mehdi Ghasemi, Razieh Mohammad Jafari & Ahmad Reza Dehpour. (2021) Beyond its anti‐migraine properties, sumatriptan is an anti‐inflammatory agent: A systematic review . Drug Development Research 82:7, pages 896-906.
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Ping Gu, Cheng Chen, Qian Wu, Changhong Dong, Teng Wang, Qi Wan & Xin Dong. (2021) The Effect and Safety of 5-HT1F Receptor Agonist Lasmiditan on Migraine: A Systematic Review and Meta-Analysis. BioMed Research International 2021, pages 1-14.
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Juliana K Beauchene & Terri L Levien. (2021) Lasmiditan: Acute Migraine Treatment Without Vasoconstriction. A Review. Journal of Pharmacy Technology 37:5, pages 244-253.
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Damiana Scuteri & Giacinto Bagetta. (2021) Progress in the Treatment of Migraine Attacks: From Traditional Approaches to Eptinezumab. Pharmaceuticals 14:9, pages 924.
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Paul A DeJulio, Joshua K Perese, Nathaniel M Schuster & Jessica C Oswald. (2021) Lasmiditan for the acute treatment of migraine. Pain Management 11:5, pages 437-449.
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Sijie Huang, Peiyu Xu, Yangxia Tan, Chongzhao You, Yumu Zhang, Yi Jiang & H. Eric Xu. (2021) Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F–G protein complex. Cell Research 31:9, pages 1036-1038.
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Johra Khan, Lubna Ibrahim Al Asoom, Ahmad Al Sunni, Nazish Rafique, Rabia Latif, Seham Al Saif, Noor B. Almandil, Dana Almohazey, Sayed AbdulAzeez & J. Francis Borgio. (2021) Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine. Biomedicine & Pharmacotherapy 139, pages 111557.
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Himanshu Suri & Jessica Ailani. (2021) Cluster Headache: A Review and Update in Treatment. Current Neurology and Neuroscience Reports 21:7.
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Linda Al-Hassany & Antoinette MaassenVanDenBrink. (2021) Drug interactions and risks associated with the use of triptans, ditans and monoclonal antibodies in migraine. Current Opinion in Neurology 34:3, pages 330-338.
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Anroop B. Nair, Jigar Shah, Shery Jacob, Bandar E. Al-Dhubiab, Vimal Patel, Nagaraja Sreeharsha & Pottathil Shinu. (2021) Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation. Pharmaceutics 13:5, pages 728.
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Mika KOMORI, Hanaka MIMURA, Max TSAI, Akichika OZEKI, Go TAKAICHI & Darren WILBRAHAM. (2020) Safety, Tolerability, and Pharmacokinetics of Lasmiditan in Healthy Japanese and Caucasian Subjects. Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 51:3, pages 119-127.
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Rajagopalan Vijayaraghavan. (2020) Autoinjector device for rapid administration of drugs and antidotes in emergency situations and in mass casualty management. Journal of International Medical Research 48:5, pages 030006052092601.
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Claudia Sorbi, Annalisa Tait, Umberto M. Battisti & Livio Brasili. (2020) Spiroxatrine derivatives towards 5-HT1A receptor selectivity. Pharmacological Reports 72:2, pages 427-434.
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Volker Neugebauer. 2020. Handbook of the Behavioral Neurobiology of Serotonin. Handbook of the Behavioral Neurobiology of Serotonin 309 320 .
Zhuo-Ying Tao, Pei-Xing Wang, Si-Qi Wei, Richard J. Traub, Jin-Feng Li & Dong-Yuan Cao. (2019) The Role of Descending Pain Modulation in Chronic Primary Pain: Potential Application of Drugs Targeting Serotonergic System. Neural Plasticity 2019, pages 1-16.
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Andrea Negro, Paolo Sciattella, Daniele Rossi, Martina Guglielmetti, Paolo Martelletti & Francesco Saverio Mennini. (2019) Cost of chronic and episodic migraine patients in continuous treatment for two years in a tertiary level headache Centre. The Journal of Headache and Pain 20:1.
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Yu Wang, Yajun Shi, Xiaofei Zhang, Junbo Zou, Yulin Liang, Jia Tai, Mei Wang, Chunli Cui & Dongyan Guo. (2019) A Chinese Prescription Chuanxiong Chatiao San for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-17.
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Carey D. Balaban, Robert D. Black & Stephen D. Silberstein. (2019) Vestibular Neuroscience for the Headache Specialist. Headache: The Journal of Head and Face Pain 59:7, pages 1109-1127.
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