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Review

Animal models of epilepsy: use and limitations

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Pages 1693-1705 | Published online: 09 Sep 2014

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Mukaddes Pala, Ismail Meral, Nilgun Pala Acikgoz, Şenay Gorucu Yilmaz, Elif Taslidere, Sema Karaca Okur, Seyma Acar & Fahri Akbas. (2022) Pentylenetetrazole-induced kindling rat model: miR-182 and miR-27b-3p mediated neuroprotective effect of thymoquinone in the hippocampus. Neurological Research 44:8, pages 726-737.
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Verónica Custodio, Jorge Acosta, Carmen Rubio, Leonardo Hernández, Javier Brito & Elisa Taddei. (2022) Accurate Neurosurgery for the Establishment of the Electric Kindling Model of Epilepsy in Mice. Journal of Investigative Surgery 35:6, pages 1253-1262.
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Fatemeh Saberi, Farideh Bahrami, Mehdi Saberi & Mahdi Mashhadi Akbar Boojar. (2022) The pro-convulsant effects of diazinon low dose in male rats under amygdala kindling. Drug and Chemical Toxicology 45:2, pages 625-632.
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Aras Erdil, Mustafa Sami Demirsoy, Sefa Çolak, Esra Duman, Orhan Sümbül & Hatice Aygun. (2021) The effect of dexketoprofen trometamol on WAG/Rij rats with absence epilepsy (dexketoprofen in absence epilepsy). Neurological Research 43:12, pages 1116-1125.
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Morteza Gholami, Ehsan Saboory, Ali Asghar Ahmadi, Mohsen Asouri, Mehrab Nasirikenari & Mostafa Rostamnezhad. (2020) Long-time effects of prenatal morphine, tramadol, methadone, and buprenorphine exposure on seizure and anxiety in immature rats. International Journal of Neuroscience 130:9, pages 898-905.
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Huajun Yang, Wei Shan, Fei Zhu, Tingting Yu, Jingjing Fan, Anchen Guo, Fei Li, Xiaofeng Yang & Qun Wang. (2019) C-Fos mapping and EEG characteristics of multiple mice brain regions in pentylenetetrazol-induced seizure mice model. Neurological Research 41:8, pages 749-761.
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Ashish Dhir. (2019) An update of cyclooxygenase (COX)-inhibitors in epilepsy disorders. Expert Opinion on Investigational Drugs 28:2, pages 191-205.
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Leila Moezi, Siranoush Yahosseini, Akram Jamshidzadeh, Mona Dastgheib & Fateme Pirsalami. (2018) Sub-chronic boldine treatment exerts anticonvulsant effects in mice. Neurological Research 40:2, pages 146-152.
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Ubedul Hoda, Nidhi Bharal Agarwal, Divya Vohora, Suhel Parvez & Sheikh Raisuddin. (2017) Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice. Nutritional Neuroscience 20:9, pages 497-504.
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Gülsel Yurtdaş Kırımlıoğlu, Yusuf Menceloğlu, Kevser Erol & Yasemin Yazan. (2016) In vitro/in vivo evaluation of gamma-aminobutyric acid-loadedN,N-dimethylacrylamide-based pegylated polymeric nanoparticles for brain delivery to treat epilepsy. Journal of Microencapsulation 33:7, pages 625-635.
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