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Original Research

Intravitreal aflibercept versus intravitreal ranibizumab for the treatment of diabetic macular edema

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Pages 567-571 | Published online: 23 Mar 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Fernando Munayco-Guillén, Miguel Angel Vazquez-Membrillo, Marlon Rafael Garcia-Roa, Jhony Alberto De La Cruz-Vargas, Herney Andrés García-Perdomo & Rafael Pichardo-Rodriguez. (2023) Effectiveness of the Use of Three-Dose Intravitreal Ziv-Aflibercept in the Management of Diabetic Macular Edema in a Real-Life Setting. Clinical Ophthalmology 17, pages 1129-1135.
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Moein Ebrahimi, Maryam Balibegloo & Nima Rezaei. (2022) Monoclonal antibodies in diabetic retinopathy. Expert Review of Clinical Immunology 18:2, pages 163-178.
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Daniele Veritti, Valentina Sarao, Valentina Soppelsa & Paolo Lanzetta. (2021) Managing Diabetic Macular Edema in Clinical Practice: Systematic Review and Meta-Analysis of Current Strategies and Treatment Options. Clinical Ophthalmology 15, pages 375-385.
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Esra Türkseven Kumral & Nimet Yeşim Erçalık. (2021) Intravitreal Ranibizumab Versus Aflibercept for Diabetic Macular Edema in Vitrectomized Eyes: 12 Month Results. Seminars in Ophthalmology 36:8, pages 723-727.
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Havva Kaldırım, Serpil Yazgan, Ahmet Kırgız, Kursat Atalay & Fatma Savur. (2019) A Comparison Study of Ranibizumab and Aflibercept in Patients with Naive Diabetic Macular Edema in Presence of Serous Retinal Detachment. Current Eye Research 44:9, pages 987-993.
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Rafael Campos Polo, Consuelo Rubio Sánchez, Diego Manuel García Guisado & María José Díaz Luque. (2018) Aflibercept for clinically significant diabetic macular edema: 12-month results in daily clinical practice. Clinical Ophthalmology 12, pages 99-104.
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Mihaela Popescu, Cătălina Bogdan, Adela Pintea, Dumitriţa Rugină & Corina Ionescu. (2018) Antiangiogenic cytokines as potential new therapeutic targets for resveratrol in diabetic retinopathy. Drug Design, Development and Therapy 12, pages 1985-1996.
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Magdalena Edington, Julie Connolly & Ngaihang Victor Chong. (2017) Pharmacokinetics of intravitreal anti-VEGF drugs in vitrectomized versus non-vitrectomized eyes. Expert Opinion on Drug Metabolism & Toxicology 13:12, pages 1217-1224.
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Articles from other publishers (17)

Xiao Xie, Chao Lian, Zhiping Zhang, Meng Feng, Wenqi Wang, Xiaomeng Yuan, Yanmei Shi & Tingting Liu. (2023) Aflibercept for long-term treatment of diabetic macular edema and proliferative diabetic retinopathy: a meta-analysis. Frontiers in Endocrinology 14.
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Patrick Wang, Zoe Hu, Maggie Hou, Patrick A. Norman, Eric K. Chin & David RP Almeida. (2022) Relationship Between Macular Thickness and Visual Acuity in the Treatment of Diabetic Macular Edema With Anti-VEGF Therapy: Systematic Review. Journal of VitreoRetinal Diseases 7:1, pages 57-64.
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Amin E. Nawar, Tamer Wasfy & Heba M. Shafik. (2022) Switching to ziv-aflibercept in resistant diabetic macular edema non responsive to ranibizumab injection. BMC Ophthalmology 22:1.
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Kübra Özata Gündoğdu, Emine Doğan, Erkan Çelik & Gürsoy Alagöz. (2022) Effect of intravitreal ranibizumab on serous retinal detachment in diabetic macular edema. Journal of Diabetes and its Complications 36:7, pages 108228.
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Sangeetha Santhakumaran, Ali Salimi, VanessaC Brunetti & John Galic. (2022) Efficacy and safety of aflibercept therapy for diabetic macular edema: A systematic review and meta-analysis. Journal of Current Ophthalmology 34:2, pages 133.
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Xuexue Zhang, Yi Liu, Miaoran Wang, Qiuyan Li, Wantong Zhang, Rui Zhang & Yufei Wu. (2021) Efficacy of Antiangiogenic Drugs in the Treatment of Diabetic Macular Edema: A Bayesian Network Analysis. Frontiers in Pharmacology 12.
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Chu-Hsuan Huang, Chang-Hao Yang, Yi-Ting Hsieh, Chung-May Yang, Tzyy-Chang Ho & Tso-Ting Lai. (2021) Hyperreflective foci in predicting the treatment outcomes of diabetic macular oedema after anti-vascular endothelial growth factor therapy. Scientific Reports 11:1.
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Ahmet EKİZOĞLU & Murat ÇAKMAKLIOĞULLARI. (2021) Comparison of the efficacy of aflibercept and ranibizumab after a 3-month loading dose in patients with diabetic macular edema. Journal of Surgery and Medicine 5:3, pages 299-302.
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B. Holbach, F. Zeman, H. Helbig & M. A. Gamulescu. (2019) Ranibizumab und Aflibercept bei diabetischem Makulaödem – Retrospektive Studie mit Ergebnissen aus dem klinischen Alltag nach 12 MonatenRanibizumab and aflibercept for diabetic macular edema—retrospective study with real-life data after 12 months. Der Ophthalmologe 117:7, pages 687-692.
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Abdullah Ozkaya, Gokhan Demir & Asli Kirmaci. (2019) Comparison of aflibercept and ranibizumab in diabetic macular edema associated with subretinal detachment. European Journal of Ophthalmology 30:2, pages 363-369.
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Pablo Plaza-Ramos, Enrique Borque & Alfredo García-Layana. (2019) Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice. PLOS ONE 14:10, pages e0223793.
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Abeer M. Khattab, Sherein M. Hagras, AhmedHosni AbdElhamid, Magda A. Torky, Eman A. Awad & Ameera G. Abdelhameed. (2019) Aflibercept with adjuvant micropulsed yellow laser versus aflibercept monotherapy in diabetic macular edema. Graefe's Archive for Clinical and Experimental Ophthalmology 257:7, pages 1373-1380.
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Ba' Pham, Sonia M Thomas, Erin Lillie, Taehoon Lee, Jemila Hamid, Trevor Richter, Ghayath Janoudi, Arnav Agarwal, Jane P Sharpe, Alistair Scott, Rachel Warren, Ronak Brahmbhatt, Erin Macdonald, Sharon E Straus & Andrea C Tricco. (2019) Anti-vascular endothelial growth factor treatment for retinal conditions: a systematic review and meta-analysis. BMJ Open 9:5, pages e022031.
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Jianshu Yuan. (2019) Role of inflammatory factors in the effects of aflibercept or ranibizumab treatment for alleviating wet age‑associated macular degeneration. Experimental and Therapeutic Medicine.
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Hajin TchoeSang Jin ShinJae Kyung SuhSonghee ChoJangmi YangMin Joo KangDonghyun Jee. (2019) Meta-analysis of Intravitreal Injection of Anti-vascular Endothelial Growth Factors for Diabetic Macular Edema. Journal of the Korean Ophthalmological Society 60:2, pages 144.
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Gianni Virgili, Mariacristina Parravano, Jennifer R Evans, Iris Gordon & Ersilia Lucenteforte. (2018) Anti-vascular endothelial growth factor for diabetic macular oedema: a network meta-analysis. Cochrane Database of Systematic Reviews 2018:10.
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Gianni Virgili, Mariacristina Parravano, Jennifer R Evans, Iris Gordon & Ersilia Lucenteforte. (2017) Anti-vascular endothelial growth factor for diabetic macular oedema: a network meta-analysis. Cochrane Database of Systematic Reviews.
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