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Case Series

Transcorneal electrical stimulation increases chorioretinal blood flow in normal human subjects

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Pages 1441-1446 | Published online: 06 Dec 2010

Keep up to date with the latest research on this topic with citation updates for this article.

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E. L. Pavlova, R. V. Semenov & A. B. Guekht. (2020) Effect of tDCS on Fine Motor Control of Patients in Subacute and Chronic Post-Stroke Stages. Journal of Motor Behavior 52:4, pages 383-395.
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Laurie Chaikin, Kellen Kashiwa, Michael Bennet, George Papastergiou & Walter Gregory. (2015) Microcurrent stimulation in the treatment of dry and wet macular degeneration. Clinical Ophthalmology 9, pages 2345-2353.
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Articles from other publishers (37)

Sandra Wagner, Esra Süer, Bishesh Sigdel, Eberhart Zrenner & Torsten Strasser. (2023) Monocular transcorneal electrical stimulation induces ciliary muscle thickening in contralateral eye. Experimental Eye Research 231, pages 109475.
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Stephen K. Agadagba, Lee Wei Lim & Leanne Lai Hang Chan. (2023) Advances in transcorneal electrical stimulation: From the eye to the brain. Frontiers in Cellular Neuroscience 17.
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Alfred Stett, Andreas Schatz, Florian Gekeler & Jeremy Franklin. (2023) Transcorneal Electrical Stimulation Dose-Dependently Slows the Visual Field Loss in Retinitis Pigmentosa. Translational Vision Science & Technology 12:2, pages 29.
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Jinfeng Liu, Andre K.H. Ma, Kwok Fai So, Vincent W.H. Lee & Kin Chiu. (2022) Mechanisms of electrical stimulation in eye diseases: A narrative review. Advances in Ophthalmology Practice and Research 2:2, pages 100060.
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Didem Dizdar Yigit, Mehmet Orkun Sevik & Özlem Şahin. (2022) TRANSCORNEAL ELECTRICAL STIMULATION THERAPY MAY HAVE A STABILIZATION EFFECT ON MULTIFOCAL ELECTRORETINOGRAPHY FOR PATIENTS WITH RETINITIS PIGMENTOSA. Retina 42:5, pages 923-933.
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Carl Erb, Sophie Eckert, Pia Gindorf, Martin Köhler, Thomas Köhler, Lukas Neuhann, Thomas Neuhann, Nadja Salzmann, Stefanie Schmickler & Jens Ellrich. (2022) Electrical neurostimulation in glaucoma with progressive vision loss. Bioelectronic Medicine 8:1.
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Zerin M. Khan, Emily Wilts, Eli Vlaisavljevich, Timothy E. Long & Scott S. Verbridge. (2021) Electroresponsive Hydrogels for Therapeutic Applications in the Brain. Macromolecular Bioscience 22:2, pages 2100355.
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Wing-Shan Yu, So-Hyun Kwon, Stephen Kugbere Agadagba, Leanne-Lai-Hang Chan, Kah-Hui Wong & Lee-Wei Lim. (2021) Neuroprotective Effects and Therapeutic Potential of Transcorneal Electrical Stimulation for Depression. Cells 10:9, pages 2492.
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Jinfeng Liu, Kelvin Tong, Youhong Lin, Vincent W.H. Lee, Kwok Fai So, Kendrick Co Shih, Jimmy S.M. Lai & Kin Chiu. (2021) Effectiveness of Microcurrent Stimulation in Preserving Retinal Function of Blind Leading Retinal Degeneration and Optic Neuropathy: A Systematic Review. Neuromodulation: Technology at the Neural Interface 24:6, pages 992-1002.
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Leonardo Colombo, Anna Caretti, Michele Dei Cas, Francesco Luciano, Dario Romano, Rita Paroni, Fabio Patelli, Riccardo Ghidoni & Luca Rossetti. (2021) Vitreous composition modification after transpalpebral electrical stimulation of the eye: Biochemical analysis. Experimental Eye Research 207, pages 108601.
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Neslihan Sinim KahramanAyse Oner. (2020) Effect of Transcorneal Electrical Stimulation on Patients with Retinitis Pigmentosa. Journal of Ocular Pharmacology and Therapeutics 36:8, pages 609-617.
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Paolo Giuseppe Limoli, Celeste Silvana Serena Limoli, Marco Ulises Morales & Enzo Maria Vingolo. (2020) Mesenchymal stem cell surgery, rescue and regeneration in retinitis pigmentosa: clinical and rehabilitative prognostic aspects. Restorative Neurology and Neuroscience 38:3, pages 223-237.
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Bernhard A. Sabel, Aini Ismafairus Abd Hamid, Carolin Borrmann, Oliver Speck & Andrea Antal. (2020) Transorbital alternating current stimulation modifies BOLD activity in healthy subjects and in a stroke patient with hemianopia: A 7 Tesla fMRI feasibility study. International Journal of Psychophysiology 154, pages 80-92.
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B. A. Sabel, J. Wang, S. Fähse, L. Cárdenas-Morales & A. Antal. (2020) Personality and stress influence vision restoration and recovery in glaucoma and optic neuropathy following alternating current stimulation: implications for personalized neuromodulation and rehabilitation. EPMA Journal 11:2, pages 177-196.
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Hamurcu Mualla Sahin, Aydogmuş Sema Akkan & Saricaglu M Sinan. (2020) Evaluation of the efficacy of transcorneal electric stimulation therapy in retinitis pigmentosa patients with electrophysiological and structural tests. International Journal of Clinical and Experimental Ophthalmology 4:1, pages 031-037.
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Bernhard A. Sabel, Gregor Thut, Jens Haueisen, Petra Henrich-Noack, Christoph S. Herrmann, Alexander Hunold, Thomas Kammer, Barbara Matteo, Elena G. Sergeeva, Wioletta Waleszczyk & Andrea Antal. (2020) Vision modulation, plasticity and restoration using non-invasive brain stimulation – An IFCN-sponsored review. Clinical Neurophysiology 131:4, pages 887-911.
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Xiaofan Su, Hao Zheng, Qian Li, Pengcheng Sun, Meixuan Zhou, Heng Li, Jiahui Guo, Xinyu Chai & Chuanqing Zhou. (2020) Retinal neurovascular responses to transcorneal electrical stimulation measured with optical coherence tomography. Experimental Biology and Medicine 245:4, pages 289-300.
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Jasleen K. Jolly, Siegfried K. Wagner, Peter Martus, Robert E. MacLaren, Barbara Wilhelm, Andrew R. Webster, Susan M. Downes, Peter Charbel Issa, Ulrich Kellner, Herbert Jägle, Klaus Rüther, Mette Bertelsen, Ragnheiður Bragadóttir , Josephine Prener Holtan, L. Ingeborgh van den Born, Andrea Sodi, Gianni Virgili, Mariya Gosheva, Johanna Pach, Ida Zündorf, Eberhart Zrenner & Florian Gekeler. (2020) Transcorneal Electrical Stimulation for the Treatment of Retinitis Pigmentosa: A Multicenter Safety Study of the OkuStim® System (TESOLA-Study). Ophthalmic Research 63:3, pages 234-243.
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Maria della Volpe-Waizel, Hanna Camenzind Zuche, Ursula Müller, Annekatrin Rickmann, Hendrik P. N. Scholl & Margarita G. Todorova. (2019) Metabolic monitoring of transcorneal electrical stimulation in retinitis pigmentosa. Graefe's Archive for Clinical and Experimental Ophthalmology 258:1, pages 79-87.
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Stefanie Freitag, Alexander Hunold, Matthias Klemm, Sascha Klee, Dietmar Link, Edgar Nagel & Jens Haueisen. (2019) Pulsed Electrical Stimulation of the Human Eye Enhances Retinal Vessel Reaction to Flickering Light. Frontiers in Human Neuroscience 13.
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Gen Miura, Takeshi Sugawara, Yohei Kawasaki, Tomoaki Tatsumi, Tomohiro Nizawa, Takayuki Baba, Hideki Hanaoka & Shuichi Yamamoto. (2019) Clinical Trial to Evaluate Safety and Efficacy of Transdermal Electrical Stimulation on Visual Functions of Patients with Retinitis Pigmentosa. Scientific Reports 9:1.
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T. Blechschmidt, M. Krumsiek & M. G. Todorova. 2019. Flammer Syndrome. Flammer Syndrome 351 369 .
Machelle T. Pardue & Rachael S. Allen. (2018) Neuroprotective strategies for retinal disease. Progress in Retinal and Eye Research 65, pages 50-76.
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Norman Waugh, Emma Loveman, Jill Colquitt, Pamela Royle, Jian Lee Yeong, Geraldine Hoad & Noemi Lois. (2018) Treatments for dry age-related macular degeneration and Stargardt disease: a systematic review. Health Technology Assessment 22:27, pages 1-168.
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Ava K. Bittner, Kenneth Seger, Rachel Salveson, Samantha Kayser, Natalia Morrison, Patricia Vargas, Deborah Mendelsohn, Jorge Han, Hua Bi, Gislin Dagnelie, Alexandra Benavente & Jessica Ramella-Roman. (2018) Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa. Acta Ophthalmologica 96:3, pages e366-e376.
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NajamA Sharif. (2018) Glaucomatous optic neuropathy treatment options: the promise of novel therapeutics, techniques and tools to help preserve vision. Neural Regeneration Research 13:7, pages 1145.
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Siegfried K Wagner, Jasleen K Jolly, Maria Pefkianaki, Florian Gekeler, Andrew R Webster, Susan M Downes & Robert E Maclaren. (2017) Transcorneal electrical stimulation for the treatment of retinitis pigmentosa: results from the TESOLAUK trial. BMJ Open Ophthalmology 2:1, pages e000096.
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T. Röck, L. Naycheva, G. Willmann, B. Wilhelm, T. Peters, E. Zrenner, K. U. Bartz-Schmidt, F. Gekeler & A. Schatz. (2016) Transkorneale Elektrostimulation bei primärem OffenwinkelglaukomTranscorneal electrical stimulation in primary open angle glaucoma. Der Ophthalmologe 114:10, pages 922-929.
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Abby Leigh Manthey, Wei Liu, Zhi Xin Jiang, Marcus Hiu Kong Lee, Jian Ji, Kwok-Fai So, Jimmy Shiu Ming Lai, Vincent Wing Hong Lee & Kin Chiu. (2017) Using Electrical Stimulation to Enhance the Efficacy of Cell Transplantation Therapies for Neurodegenerative Retinal Diseases: Concepts, Challenges, and Future Perspectives. Cell Transplantation 26:6, pages 949-965.
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Petra Henrich-Noack, ElenaG Sergeeva & BernhardA Sabel. (2017) Non-invasive electrical brain stimulation: from acute to late-stage treatment of central nervous system damage. Neural Regeneration Research 12:10, pages 1590.
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Eric L. Singman, Nitin Daphalapurkar, Helen White, Thao D. Nguyen, Lijo Panghat, Jessica Chang & Timothy McCulley. (2016) Indirect traumatic optic neuropathy. Military Medical Research 3:1.
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Amer Sehic, Shuai Guo, Kin-Sang Cho, Rima M. Corraya, Dong F. Chen & Tor P. Utheim. (2016) Electrical Stimulation as a Means for Improving Vision. The American Journal of Pathology 186:11, pages 2783-2797.
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T. Röck, L. Naycheva, G. Willmann, A. Schatz, B. Wilhelm, T. Peters, E. Zrenner, K.U. Bartz-Schmidt & F. Gekeler. (2014) RETRACTED ARTICLE: Transkorneale Elektrostimulation bei Patienten mit primärem Offenwinkelglaukom. Der Ophthalmologe 112:8, pages 694-694.
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Takeshi Morimoto, Hiroyuki Kanda, Tomomitsu Miyoshi, Yoko Hirohara, Toshifumi Mihashi, Yoshiyuki Kitaguchi, Kohji Nishida & Takashi Fujikado. (2014) Characteristics of Retinal Reflectance Changes Induced by Transcorneal Electrical Stimulation in Cat Eyes. PLoS ONE 9:3, pages e92186.
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Lauren N. Ayton, Robyn H. Guymer, Penelope J. Allen & Chi D. Luu. 2014. Regenerative Biology of the Eye. Regenerative Biology of the Eye 257 273 .
Lubka Naycheva, Andreas Schatz, Gabriel Willmann, Karl Ulrich Bartz-Schmidt, Eberhart Zrenner, Tobias Röck & Florian Gekeler. (2013) Transcorneal Electrical Stimulation in Patients with Retinal Artery Occlusion: A Prospective, Randomized, Sham-Controlled Pilot Study. Ophthalmology and Therapy 2:1, pages 25-39.
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Florian Gekeler & Karl Ulrich Bartz-Schmidt. (2012) Electrical stimulation — a therapeutic strategy for retinal and optic nerve disease?. Graefe's Archive for Clinical and Experimental Ophthalmology 250:2, pages 161-163.
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