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OncoTargets and Therapy Volume 9, 2016 - Issue

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Original Research

Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia

Yu-Jen Chen1 Department of Medical Research;2 Department of Radiation Oncology, Mackay Memorial Hospital;3 Institute of Traditional Medicine, School of Medicine, National Yang-Ming University;4 Institute of Pharmacology, Taipei Medical University, Taipei

Li-Wen Fang5 Department of Nutrition, I-Shou University, Kaohsiung

Wen-Chi Su6 Research Center for Emerging Viruses, China Medical University Hospital;7 Graduate Institute of Clinical Medical Science, China Medical University, Taichung

Wen-Yi Hsu1 Department of Medical Research

Kai-Chien Yang1 Department of Medical Research

Huey-Lan Huang8 Department of Bioscience Technology, College of Health Science, Chang Jung Christian University, Tainan, Taiwan, Republic of ChinaCorrespondence[email protected]

Pages 4453-4464 | Published online: 20 Jul 2016

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Hongxia Ma, Yang Liu, Zhen Miao, Shijia Cheng, Yunan Zhu, Yifan Wu, Xinxin Fan, Jing Yang, Xingang Li & Liyin Guo. (2022) Neratinib inhibits proliferation and promotes apoptosis of acute myeloid leukemia cells by activating autophagy‐dependent ferroptosis. Drug Development Research 83:7, pages 1641-1653.
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Feng Jiang, Chuyan Wu, Ming Wang, Ke Wei & Jimei Wang. (2022) An Autophagy-related Long Non-coding RNA Signature for Breast Cancer. Combinatorial Chemistry & High Throughput Screening 25:8, pages 1327-1335.
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Angel Y.F. Kam, Sadhna O. Piryani, Chang-Lung Lee, David A. Rizzieri, Neil L. Spector, Stefanie Sarantopoulos & Phuong L. Doan. (2021) Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells. Molecular Cancer Research 19:5, pages 886-899.
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Marta Pérez-Hernández, Alain Arias, David Martínez-García, Ricardo Pérez-Tomás, Roberto Quesada & Vanessa Soto-Cerrato. (2019) Targeting Autophagy for Cancer Treatment and Tumor Chemosensitization. Cancers 11:10, pages 1599.
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Olivier Ballo, Jan Stratmann, Hubert Serve, Björn Steffen, Fabian Finkelmeier & Christian Brandts. (2019) Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy. PLOS ONE 14:9, pages e0223013.
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Yi-Shing Leu, Yu-Jen Chen, Chien-Chih Chen & Huey-Lan Huang. (2019) Induction of Autophagic Death of Human Hepatocellular Carcinoma Cells by Armillaridin from Armillaria mellea . The American Journal of Chinese Medicine 47:06, pages 1365-1380.
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Shani Bialik, Santosh K. Dasari & Adi Kimchi. (2018) Autophagy-dependent cell death – where, how and why a cell eats itself to death. Journal of Cell Science 131:18.
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Wei Guo, Bin Zhang, Kun Mu, Shi-Qing Feng, Zhan-Yin Dong, Guang-Zhi Ning, Hao-Ran Li, Shen Liu, Ling Zhao, Yan Li, Bing-Bing Yu, Hui-Quan Duan, Chao Sun & Yong-Jin Li. (2018) Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk. Cell Death & Disease 9:3.
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Tatiana V. Denisenko, Inna N. Budkevich & Boris Zhivotovsky. (2018) Cell death-based treatment of lung adenocarcinoma. Cell Death & Disease 9:2.
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Lu Liu, Liang Zhong, Yi Zhao, Min Chen, Shifei Yao, Lianwen Li, Chunlan Xiao, Zhiling Shan, Liugen Gan, Ting Xu & Beizhong Liu. (2017) Effects of lapatinib on cell proliferation and apoptosis in NB4 cells. Oncology Letters.
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N. P. Bgatova, Yu. S. Gavrilova, A. P. Lykov, A. O. Solovieva, V. V. Makarova, Yu. I. Borodin & V. I. Konenkov. (2017) Apoptosis and autophagy in hepatocarcinoma cells induced by different forms of lithium salts. Cell and Tissue Biology 11:4, pages 261-267.
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Elizabeth Henson, Yongqiang Chen & Spencer Gibson. (2017) EGFR Family Members’ Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer. Cancers 9:12, pages 27.
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Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia

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Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia

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