Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia

References

• HatzimichaelEGeorgiouGBenetatosLBriasoulisEGene mutations and molecularly targeted therapies in acute myeloid leukemiaAm J Blood Res201331295123358589
   PubMedGoogle Scholar
• TallmanMSGillilandDGRoweJMDrug therapy for acute myeloid leukemiaBlood200510641154116315870183
   PubMed Web of Science ®Google Scholar
• KellyLMGillilandDGGenetics of myeloid leukemiasAnnu Rev Genomics Hum Genet2002317919812194988
   PubMed Web of Science ®Google Scholar
• BoehrerSAdesLGalluzziLErlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparisonBiochem Pharmacol200876111417142518617157
   PubMed Web of Science ®Google Scholar
• BoehrerSAdesLBraunTErlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical studyBlood200811142170218017925489
   PubMed Web of Science ®Google Scholar
• MacFarlaneRJGelmonKALapatinib for breast cancer: a review of the current literatureExpert Opin Drug Saf201110110912121091041
   PubMed Web of Science ®Google Scholar
• RusnakDWAlligoodKJMullinRJAssessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb, GW572016) in an expanded panel of human normal and tumour cell linesCell Prolif200740458059417635524
   PubMed Web of Science ®Google Scholar
• RusnakDWLackeyKAffleckKThe effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivoMol Cancer Ther200112859412467226
   PubMed Web of Science ®Google Scholar
• HolbroTHynesNEErbB receptors: directing key signaling networks throughout lifeAnnu Rev Pharmacol Toxicol20044419521714744244
   PubMed Web of Science ®Google Scholar
• KopperLLapatinib: a sword with two edgesPathol Oncol Res20081411818409020
   PubMed Web of Science ®Google Scholar
• ItoYTokudomeNSugiharaTTakahashiSHatakeKDoes lapatinib, a small-molecule tyrosine kinase inhibitor, constitute a breakthrough in the treatment of breast cancer?Breast Cancer200714215616217485900
   PubMedGoogle Scholar
• TevaarwerkAJKolesarJMLapatinib: a small-molecule inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor-2 tyrosine kinases used in the treatment of breast cancerClin Ther200931Pt 22332234820110044
   PubMed Web of Science ®Google Scholar
• RyanQIbrahimACohenMHFDA drug approval summary: lapatinib in combination with capecitabine for previously treated metastatic breast cancer that overexpresses HER-2Oncologist200813101114111918849320
   PubMed Web of Science ®Google Scholar
• SpiraAICarducciMADifferentiation therapyCurr Opin Pharmacol20033433834312901941
   PubMed Web of Science ®Google Scholar
• HonmaYMatsuoYHayashiYOmuraSTreatment of Philadelphia-chromosome-positive human leukemia in SCID mouse model with herbimycin A, bcr-abl tyrosine kinase activity inhibitorInt J Cancer19956056856887860143
   PubMed Web of Science ®Google Scholar
• MorceauFDupontCPalissotVGTP-mediated differentiation of the human K562 cell line: transient overexpression of GATA-1 and stabilization of the gamma-globin mRNALeukemia20001491589159710995005
   PubMed Web of Science ®Google Scholar
• MeshkiniAYazdanparastRInvolvement of ERK/MAPK pathway in megakaryocytic differentiation of K562 cells induced by 3-hydrogenkwadaphninToxicol In Vitro20082261503151018586450
   PubMed Web of Science ®Google Scholar
• WilliamsCAMondalDAgrawalKCThe HIV-1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBPExp Biol Med (Maywood)20052301187288416339753
   PubMed Web of Science ®Google Scholar
• RouyezMCBoucheronCGisselbrechtSDusanter-FourtIPorteuFControl of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathwayMol Cell Biol1997179499150009271377
   PubMed Web of Science ®Google Scholar
• TetterooPAMassaroFMulderASchreuder-van GelderRvon dem BorneAEMegakaryoblastic differentiation of proerythroblastic K562 cell-line cellsLeuk Res1984821972066232432
   PubMed Web of Science ®Google Scholar
• ChenYJChiCWSuWCHuangHLLapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinomaOncotarget20145134845485424947784
   PubMedGoogle Scholar
• HuangHLChenYCHuangYCLapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia k562 cellsPLoS One2011612e2901422216158
   PubMed Web of Science ®Google Scholar
• ChenYJHuangWPYangYCPlatonin induces autophagy-associated cell death in human leukemia cellsAutophagy20095217318319066447
   PubMed Web of Science ®Google Scholar
• DattaRYoshinagaKKanekiMPandeyPKufeDPhorbol ester-induced generation of reactive oxygen species is protein kinase cbeta-dependent and required for SAPK activationJ Biol Chem200027552410004100311042219
   PubMed Web of Science ®Google Scholar
• SuWCChaoTCHuangYLWengSCJengKSLaiMMRab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagyJ Virol20118520105611057121835792
   PubMed Web of Science ®Google Scholar
• KlionskyDJAbdallaFCAbeliovichHGuidelines for the use and interpretation of assays for monitoring autophagyAutophagy20128444554422966490
   PubMed Web of Science ®Google Scholar
• KroemerGGalluzziLVandenabeelePClassification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009Cell Death Differ200916131118846107
   PubMed Web of Science ®Google Scholar
• SchmittgenTDLeeEJJiangJReal-time PCR quantification of precursor and mature microRNAMethods2008441313818158130
   PubMed Web of Science ®Google Scholar
• MollinedoFLopez-PerezRGajateCDifferential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cellsGene20084191–2162618547747
   PubMed Web of Science ®Google Scholar
• CollinsSJRuscettiFWGallagherREGalloRCNormal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxideJ Exp Med19791494969974219131
   PubMed Web of Science ®Google Scholar
• ClergetMPollaBSErythrophagocytosis induces heat shock protein synthesis by human monocytes-macrophagesProc Natl Acad Sci U S A1990873108110852153967
   PubMed Web of Science ®Google Scholar
• PitiniVArrigoCAltavillaGErlotinib in a patient with acute myelogenous leukemia and concomitant non-small-cell lung cancerJ Clin Oncol200826213645364618640945
   PubMed Web of Science ®Google Scholar
• LindhagenEErikssonAWickstromMSignificant cytotoxic activity in vitro of the EGFR tyrosine kinase inhibitor gefitinib in acute myeloblastic leukaemiaEur J Haematol200881534435318637032
   PubMed Web of Science ®Google Scholar
• MirandaMBDuanRThomasSMGefitinib potentiates myeloid cell differentiation by ATRALeukemia20082281624162718305561
   PubMed Web of Science ®Google Scholar
• RavindranathanMKlementichFJJonesDVJrPotential interaction of chemotherapy and gefitinib in the induction of hematologic neoplasiaLeukemia200721122546254717657221
   PubMed Web of Science ®Google Scholar
• StegmaierKCorselloSMRossKNWongJSDeangeloDJGolubTRGefitinib induces myeloid differentiation of acute myeloid leukemiaBlood200510682841284815998836
   PubMed Web of Science ®Google Scholar
• TakigawaNTakeuchiMShibayamaTSuccessful treatment of a patient with synchronous advanced non-small cell lung cancer and acute myeloid leukemia by a combination of gefitinib, low-dose cytarabine and aclarubicinAnticancer Res2005253c2579258216080496
   PubMed Web of Science ®Google Scholar
• EnnishiDSezakiNSenooTTeruiYHatakeKHinoNA case of acute promyelocytic leukemia during gefitinib treatmentInt J Hematol200684328428517020873
   PubMed Web of Science ®Google Scholar
• GalluzziLAaronsonSAAbramsJGuidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotesCell Death Differ20091681093110719373242
   PubMed Web of Science ®Google Scholar
• CruickshanksNTangYBoothLHamedHGrantSDentPLapatinib and obatoclax kill breast cancer cells through reactive oxygen species-dependent endoplasmic reticulum stressMol Pharmacol20128261217122922989520
   PubMed Web of Science ®Google Scholar
• TangYHamedHACruickshanksNFisherPBGrantSDentPObatoclax and lapatinib interact to induce toxic autophagy through NOXAMol Pharmacol201281452754022219388
   PubMed Web of Science ®Google Scholar
• IrwinMENelsonLDSantiago-O’FarrillJMSmall molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemiaPLoS One201388e7060823936456
   PubMed Web of Science ®Google Scholar
• BoehrerSGalluzziLLaineyEErlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemiaCell Cycle201110183168317521897118
   PubMed Web of Science ®Google Scholar
• HahnCKBerchuckJERossKNProteomic and genetic approaches identify Syk as an AML targetCancer Cell200916428129419800574
   PubMed Web of Science ®Google Scholar
• AllenHHsuanJClarkSExpression of epidermal-growth-factor receptor in the K562 cell line by transfection. Altered receptor biochemistryBiochem J199027137857902173908
   PubMed Web of Science ®Google Scholar
• Eales-ReynoldsLJLaverHModjtahediHEvidence for the expression of the EGF receptor on human monocytic cellsCytokine200116516917211814311
   PubMed Web of Science ®Google Scholar
• LaineyESebertMThepotSErlotinib antagonizes ABC transporters in acute myeloid leukemiaCell Cycle201211214079409223095522
   PubMed Web of Science ®Google Scholar