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Original Research

Diagnostic and prognostic roles of IRAK1 in hepatocellular carcinoma tissues: an analysis of immunohistochemistry and RNA-sequencing data from the cancer genome atlas

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Pages 1711-1723 | Published online: 21 Mar 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Muwen Yang, Xingsong Qin, Guangyuan Qin & Xinyu Zheng. (2019) The role of IRAK1 in breast cancer patients treated with neoadjuvant chemotherapy. OncoTargets and Therapy 12, pages 2171-2180.
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Suliman Al-Fayoumi, Taishi Hashiguchi, Yuka Shirakata, John Mascarenhas & Jack W Singer. (2018) Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis. Journal of Experimental Pharmacology 10, pages 9-17.
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Articles from other publishers (17)

Chih-Chia Yu, Hon-Yi Lin, Chen-Hsi Hsieh, Michael W. Y. Chan, Wen-Yen Chiou, Moon-Sing Lee, Chen-Lin Chi, Ru-Inn Lin, Feng-Chun Hsu, Liang-Cheng Chen, Chia-Hui Chew, Hsuan-Ju Yang & Shih-Kai Hung. (2023) IRAK2, an Immune and Radiation-Response Gene, Correlates with Advanced Disease Features but Predicts Higher Post-Irradiation Local Control in Non-Metastatic and Resected Oral Cancer Patients. International Journal of Molecular Sciences 24:8, pages 6903.
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Chaoying Song, Xinyu Gu & Ruifang Li. (2022) Expression of IRAK1 in Hepatocellular Carcinoma, Its Clinical Significance, and Docking Characteristics with Selected Natural Compounds. Current Oncology 29:11, pages 8904-8916.
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Undraga Schagdarsurengin, Vanessa Breiding, Maria Loose, Florian Wagenlehner & Temuujin Dansranjav. (2022) Interleukin-1 receptor associated kinase 1 (IRAK1) is epigenetically activated in luminal epithelial cells in prostate cancer. Frontiers in Oncology 12.
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Jun Zou & Wan Qin. (2022) Comprehensive analysis of the cancer driver genes constructs a seven-gene signature for prediction of survival and tumor immunity in hepatocellular carcinoma. Frontiers in Genetics 13.
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Yilin Wang, Hongsheng Ma, Yajie Li & Rina Su. (2022) MiR-192-5p-Modified Tumor-Associated Macrophages-Derived Exosome Suppressed Endometrial Cancer Progression Through Targeting IRAK1/NF-κB Signaling. Reproductive Sciences 29:2, pages 436-447.
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Joshua Bennett & Daniel T. Starczynowski. (2022) IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies. Current Opinion in Hematology 29:1, pages 8-19.
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Lixia Liu, Bin Liu, Jie Yu, Dongyun Zhang, Jianhong Shi & Ping Liang. (2021) Development of a Toll-Like Receptor-Based Gene Signature That Can Predict Prognosis, Tumor Microenvironment, and Chemotherapy Response for Hepatocellular Carcinoma. Frontiers in Molecular Biosciences 8.
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Jian Hu, Zhi-Qing Zhang, Wei Zhu, Zhen-Ru Wu, Yu You, Yan Liu, Dai-Wen Su, Yun-Bing Wang & Jian-Ping Gong. (2020) Comparison of clinicopathological traits and prognostic factors of hepatocellular carcinoma with and without cirrhotic background. Carcinogenesis 41:11, pages 1576-1582.
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Dong-yue Wen, Peng Lin, Hai-wei Liang, Xia Yang, Hai-yuan Li, Yun He, Hong Yang & Gang Chen. (2018) Up-regulation of CTD-2547G23.4 in hepatocellular carcinoma tissues and its prospective molecular regulatory mechanism: a novel qRT-PCR and bioinformatics analysis study. Cancer Cell International 18:1.
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Jing‑Pei Long, Li‑Feng Dong, Fang‑Fang Chen & Yang‑Fan Fan. (2018) miR‑146a‑5p targets interleukin‑1 receptor‑associated kinase�1 to inhibit the growth, migration, and invasion of breast cancer cells. Oncology Letters.
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Mona M. Hosseini, Stephen E. Kurtz, Sherif Abdelhamed, Shawn Mahmood, Monika A. Davare, Andy Kaempf, Johannes Elferich, Jason E. McDermott, Tao Liu, Samuel H. Payne, Ujwal Shinde, Karin D. Rodland, Motomi Mori, Brian J. Druker, Jack W. Singer & Anupriya Agarwal. (2018) Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes. Leukemia 32:11, pages 2374-2387.
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Jack W. Singer, Angela Fleischman, Suliman Al-Fayoumi, John O. Mascarenhas, Qiang Yu & Anupriya Agarwal. (2018) Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy. Oncotarget 9:70, pages 33416-33439.
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Bowie Y. Cheng, Eunice Y. Lau, Hoi-Wing Leung, Carmen Oi-Ning Leung, Nicole P. Ho, Shilpa Gurung, Lily K. Cheng, Chi Ho Lin, Regina Cheuk-Lam Lo, Stephanie Ma, Irene Oi-Lin Ng & Terence K. Lee. (2018) IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma. Cancer Research 78:9, pages 2332-2342.
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Yilin Wang, Yanyan Wang, Xianzhi Duan, Yinuo Wang & Zhenyu Zhang. (2017) Interleukin‐1 receptor‐associated kinase 1 correlates with metastasis and invasion in endometrial carcinoma. Journal of Cellular Biochemistry 119:3, pages 2545-2555.
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Massimo Gadina, Nathalia Gazaniga, Laura Vian & Yasuko Furumoto. (2017) Small molecules to the rescue: Inhibition of cytokine signaling in immune-mediated diseases. Journal of Autoimmunity 85, pages 20-31.
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Min Guo, Yinghua Li, Zhengfang Lin, Mingqi Zhao, Misi Xiao, Changbing Wang, Tiantian Xu, Yu Xia & Bing Zhu. (2017) Surface decoration of selenium nanoparticles with curcumin induced HepG2 cell apoptosis through ROS mediated p53 and AKT signaling pathways. RSC Advances 7:83, pages 52456-52464.
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