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Clinical Trial Report

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

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Pages 4239-4250 | Published online: 29 Aug 2017

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Scott A Reisman, Sarabjit S Gahir, Chun-Yue I Lee, Joel W Proksch, Mitsumasa Sakamoto & Keith W Ward. (2019) Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates. Drug Design, Development and Therapy 13, pages 1259-1270.
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Matej Sova & Luciano Saso. (2018) Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review. Drug Design, Development and Therapy 12, pages 3181-3197.
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