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OncoTargets and Therapy Volume 13, 2020 - Issue
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Original Research

Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway

Yanyan Liu1 Division of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-8104-2354
ORCID Icon,
Zhucheng Yin2 Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China
,
Ping Lu2 Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China
,
Yifei Ma2 Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China
,
Bo Luo3 Department of Radiotherapy, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China
,
Lanxin Xiang4 School of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, People’s Republic of China
,
Wangli Zhang4 School of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, People’s Republic of China
,
Yu He5 Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China
&
Xinjun Liang2 Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Pages 10693-10705 | Published online: 20 Oct 2020

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Klara Cervena, Anna Siskova, Jiri Jungwirth, Marin Volarić, Jan Kral, Pavel Kohout, Miroslav Levy & Veronika Vymetalkova. (2023) MALAT1 in Liquid Biopsy: The Diagnostic and Prognostic Promise for Colorectal Cancer and Adenomas?. International Journal of General Medicine 16, pages 3517-3531.
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Articles from other publishers (17)

Karama Asleh, Valerie Dery, Catherine Taylor, Michelle Davey, Marie-Ange Djeungoue-Petga & Rodney J. Ouellette. (2023) Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology. Biomarker Research 11:1.
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Alejandro Castillo-Peña & Sonia Molina-Pinelo. (2023) Landscape of tumor and immune system cells-derived exosomes in lung cancer: mediators of antitumor immunity regulation. Frontiers in Immunology 14.
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Hongyuan Liang, Lingyun Zhang, Xiangxuan Zhao & Jian Rong. (2023) The therapeutic potential of exosomes in lung cancer. Cellular Oncology 46:5, pages 1181-1212.
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Jiafeng Cao, Weiguang Kong, Gaofeng Cheng & Zhen Xu. (2023) Role of mTORC1 Signaling in Regulating the Immune Function of Granulocytes in Teleost Fish. International Journal of Molecular Sciences 24:18, pages 13745.
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Naushad Ahmad Khan, Mohammad Asim, Kabir H. Biswas, Amani N Alansari, Harman Saman, Mohammad Zahid Sarwar, Kudaibergen Osmonaliev & Shahab Uddin. (2023) Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging concepts. Journal of Experimental & Clinical Cancer Research 42:1.
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Maria Conti, Marianna Minniti, Mariaenrica Tiné, Miriam De Francesco, Roberta Gaeta, Dario Nieri, Umberto Semenzato, Davide Biondini, Marina Camera, Manuel G. Cosio, Marina Saetta, Alessandro Celi, Erica Bazzan & Tommaso Neri. (2023) Extracellular Vesicles in Pulmonary Hypertension: A Dangerous Liaison?. Biology 12:8, pages 1099.
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Jinzhan Chen, Congyi Xie, Yimin Yang, Shuwen Yang, Jinxian Huang, Feiyang Ye, Zhenyang Lin, Lin Tong & Jiaxin Liu. (2023) Association between albumin-to-globulin ratio and the risk of overall survival in advanced non-small cell lung cancer patients with anlotinib treatment: a retrospective cohort study. BMC Pulmonary Medicine 23:1.
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Mohamed J. Saadh, Bahman Abedi Kiasari, Seyed Abbas Shahrtash, José Luis Arias-Gonzáles, MVNL Chaitanya, Juan Carlos Cotrina-Aliaga, Mustafa Jawad Kadham, Ioan Sârbu & Reza Akhavan-Sigari. (2023) Exosomal non-coding RNAs’ role in immune regulation and potential therapeutic applications. Pathology - Research and Practice 247, pages 154522.
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Huan‐Huan Yu, Wei Zhao, Bu‐Xin Zhang, Ying Wang, Jie Li & Yu‐Fu Fang. (2023) Morinda officinalis extract exhibits protective effects against atopic dermatitis by regulating the MALAT1 / miR ‐590‐5p/ CCR7 axis . Journal of Cosmetic Dermatology 22:5, pages 1602-1612.
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Meysam Najaflou, Mehdi Shahgolzari, Ahmad Yari Khosroushahi & Steven Fiering. (2022) Tumor-Derived Extracellular Vesicles in Cancer Immunoediting and Their Potential as Oncoimmunotherapeutics. Cancers 15:1, pages 82.
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Anjugam Paramanantham, Rahmat Asfiya, Siddharth Das, Grace McCully & Akhil Srivastava. (2022) Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. International Journal of Molecular Sciences 23:21, pages 13637.
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Ying-Hua Guan, Na Wang, Zhen-Wei Deng, Xi-Guang Chen & Ya Liu. (2022) Exploiting autophagy-regulative nanomaterials for activation of dendritic cells enables reinforced cancer immunotherapy. Biomaterials 282, pages 121434.
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Gracie Wee Ling Eng, Yilong Zheng, Dominic Wei Ting Yap, Andrea York Tiang Teo & Jit Kong Cheong. (2021) Autophagy and ncRNAs: Dangerous Liaisons in the Crosstalk between the Tumor and Its Microenvironment. Cancers 14:1, pages 20.
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Patrick Santos & Fausto Almeida. (2021) Exosome-Based Vaccines: History, Current State, and Clinical Trials. Frontiers in Immunology 12.
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Ping Lu, Yifei Ma, Shaozhong Wei & Xinjun Liang. (2021) The dual role of complement in cancers, from destroying tumors to promoting tumor development. Cytokine 143, pages 155522.
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Ping Lu, Yifei Ma, Shaozhong Wei & Xinjun Liang. (2021) A Low Albumin-to-Globulin Ratio Predicts a Poor Prognosis in Patients With Metastatic Non-small-cell Lung Cancer. Frontiers in Medicine 8.
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Marta Colletti, Donatella Ceglie, Angela Di Giannatale & Francesca Nazio. (2021) Autophagy and Exosomes Relationship in Cancer: Friends or Foes?. Frontiers in Cell and Developmental Biology 8.
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