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Review

Update of research on the role of EZH2 in cancer progression

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Pages 321-324 | Published online: 04 Apr 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Farnaz Boostani, Roya Dolatkhah, Ashraf Fakhrjou, Faris Farassati & Zohreh Sanaat. (2018) Association of clinicopathologic characteristics and outcomes with EZH2 expression in patients with breast cancer in East Azerbaijan, Iran. OncoTargets and Therapy 11, pages 449-457.
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Christian Mayr, Daniel Neureiter, Andrej Wagner, Martin Pichler & Tobias Kiesslich. (2015) The role of polycomb repressive complexes in biliary tract cancer. Expert Opinion on Therapeutic Targets 19:3, pages 363-375.
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Bryson W Katona, Yuanyuan Liu, Anqi Ma, Jian Jin & Xianxin Hua. (2014) EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells . Cancer Biology & Therapy 15:12, pages 1677-1687.
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Angiolo Gadducci, Claudia Sergiampietri, Nora Lanfredini & Ilaria Guiggi. (2014) Micro-RNAs and ovarian cancer: the state of art and perspectives of clinical research. Gynecological Endocrinology 30:4, pages 266-271.
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Articles from other publishers (17)

Xiangyan Zhang, Xiangli Ma, Quanxin Wang & Zhaolu Kong. (2022) EZH2 targeting to improve the sensitivity of acquired radio-resistance bladder cancer cells. Translational Oncology 16, pages 101316.
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Yifan Kong, Yanquan Zhang, Fengyi Mao, Zhuangzhuang Zhang, Zhiguo Li, Ruixin Wang, Jinghui Liu & Xiaoqi Liu. (2020) Inhibition of EZH2 Enhances the Antitumor Efficacy of Metformin in Prostate Cancer. Molecular Cancer Therapeutics 19:12, pages 2490-2501.
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Shusuke Ogihara, Toru Komatsu, Yukihiro Itoh, Yuka Miyake, Takayoshi Suzuki, Kouichi Yanagi, Yusuke Kimura, Tasuku Ueno, Kenjiro Hanaoka, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano & Yasuteru Urano. (2019) Metabolic-Pathway-Oriented Screening Targeting S -Adenosyl- l -methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols . Journal of the American Chemical Society 142:1, pages 21-26.
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Chunyan Hu, Yun Liu, Mengying Teng, Kailin Jiao, Jing Zhen, Maoxuan Wu & Zhong Li. (2019) Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling. Cell Biology and Toxicology 35:5, pages 445-456.
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Xuming Wang, Jin Duan, Weiping Fu, Zhaowu Yin, Jianing Sheng, Zhuyun Lei & Han Wang. (2019) Decreased expression of NEDD4L contributes to NSCLC progression and metastasis. Biochemical and Biophysical Research Communications 513:2, pages 398-404.
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Liang Shen, Ming Liu, Wei Liu, Jing Cui & Changzhong Li. (2017) Bioinformatics analysis of RNA sequencing data reveals multiple key genes in uterine corpus endometrial carcinoma. Oncology Letters.
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Laura Vilorio-Marqués, Vicente Martín, Cristina Diez-Tascón, María Francisca González-Sevilla, Tania Fernández-Villa, Emiliano Honrado, Veronica Davila-Batista & Antonio J. Molina. (2017) The role of EZH2 in overall survival of colorectal cancer: a meta-analysis. Scientific Reports 7:1.
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Martijn AJ Koppens, Gergana Bounova, Paulien Cornelissen-Steijger, Nienke de Vries, Owen J Sansom, Lodewyk FA Wessels & Maarten van Lohuizen. (2016) Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition. Oncotarget 7:43, pages 69816-69828.
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Ya-Tian Chen, Feng Zhu, Wei-Ren Lin, Rong-Biao Ying, You-Ping Yang & Ling-Hui Zeng. (2016) The novel EZH2 inhibitor, GSK126, suppresses cell migration and angiogenesis via down-regulating VEGF-A. Cancer Chemotherapy and Pharmacology 77:4, pages 757-765.
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B C Roy, D Subramaniam, I Ahmed, V R Jala, C M Hester, K A Greiner, B Haribabu, S Anant & S Umar. (2014) Role of bacterial infection in the epigenetic regulation of Wnt antagonist WIF1 by PRC2 protein EZH2. Oncogene 34:34, pages 4519-4530.
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Manisha Sachan & Manpreet Kaur. (2015) Epigenetic Modifications: Therapeutic Potential in Cancer. Brazilian Archives of Biology and Technology 58:4, pages 526-539.
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JIANG WANG, YE REN, XIN GUO, HAO CHENG, YAPING YE, JUN QI, CAIHONG YANG & HONGBO YOU. (2015) Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma. Molecular Medicine Reports 11:5, pages 3585-3592.
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Mingquan Sha, Genxiang Mao, Guofu Wang, Yufeng Chen, Xiaojian Wu & Zhen Wang. (2015) DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis. Acta Pharmaceutica Sinica B 5:3, pages 188-193.
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Yan-Long Liu, Xu Gao, Yang Jiang, Gan Zhang, Zi-Cheng Sun, Bin-Bin Cui & Yan-Mei Yang. (2014) Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer. Journal of Cancer Research and Clinical Oncology 141:4, pages 661-669.
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Pankaj Pathak, Prerana Jha, Suvendu Purkait, Vikas Sharma, Vaishali Suri, Mehar C. Sharma, Mohammed Faruq, Ashish Suri & Chitra Sarkar. (2014) Altered global histone-trimethylation code and H3F3A-ATRX mutation in pediatric GBM. Journal of Neuro-Oncology 121:3, pages 489-497.
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Azat R. Garipov, Alexander A. Nesmelov, Hector A. Cabrera-Fuentes & Olga N. Ilinskaya. (2014) Bacillus intermedius ribonuclease (BINASE) induces apoptosis in human ovarian cancer cells. Toxicon 92, pages 54-59.
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Arunoday Bhan, Imran Hussain, Khairul I. Ansari, Samara A.M. Bobzean, Linda I. Perrotti & Subhrangsu S. Mandal. (2014) Histone Methyltransferase EZH2 Is Transcriptionally Induced by Estradiol as Well as Estrogenic Endocrine Disruptors Bisphenol-A and Diethylstilbestrol. Journal of Molecular Biology 426:20, pages 3426-3441.
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