OncoTargets and Therapy, Volume 6, Issue (2013)

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OncoTargets and Therapy, Volume 6, Issue (2013)

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Review

Review Article
Profile of cabozantinib and its potential in the treatment of advanced medullary thyroid cancer
Christopher D Hart & Richard H De Boer
Pages: 1-7
Published online: 03 Jan 2013
AbstractforProfile of cabozantinib and its potential in the treatment of advanced medullary thyroid cancer | Full Text | References | PDF (208.3 KB)
  • 151 Views
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Open Access
Review Article
Clinical appraisal of abiraterone in the treatment of metastatic prostatic cancer: patient considerations, novel opportunities, and future directions
Diego J Bedoya & Nicholas Mitsiades
Pages: 9-18
Published online: 03 Jan 2013
AbstractforClinical appraisal of abiraterone in the treatment of metastatic prostatic cancer: patient considerations, novel opportunities, and future directions | Full Text | References | PDF (228.1 KB)
  • 72 Views
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Open Access

Short Report

Article
Expression of novel tumor markers of pancreatic adenocarcinomas in intrahepatic cholangiocarcinomas
Meijuan Zong, Lei Jia & Liang Li
Pages: 19-23
Published online: 11 Jan 2013
AbstractforExpression of novel tumor markers of pancreatic adenocarcinomas in intrahepatic cholangiocarcinomas | Full Text | References | PDF (1.1 MB)
  • 56 Views
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Open Access

Original Research

Article
Pseudomembranous colitis within radiotherapy field following concurrent chemoradiation therapy: a case report
Bing-Jie Shen, Shih-Chiang Lin, Pei-Wei Shueng, Yueh-Hung Chou, Li-Ming Tseng & Chen-Hsi Hsieh
Pages: 25-28
Published online: 17 Jan 2013
AbstractforPseudomembranous colitis within radiotherapy field following concurrent chemoradiation therapy: a case report | Full Text | References | PDF (1.3 MB)
  • 61 Views
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Open Access
Article
Dendritic cells fused with different pancreatic carcinoma cells induce different T-cell responses
Yoshiaki Andoh, Naohiko Makino & Mitsunori Yamakawa
Pages: 29-40
Published online: 22 Jan 2013
AbstractforDendritic cells fused with different pancreatic carcinoma cells induce different T-cell responses | Full Text | References | PDF (1.9 MB)
  • 70 Views
  • 1 CrossRef citations
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Open Access
Article
Circadian rhythm characteristics of oral squamous cell carcinoma growth in an orthotopic xenograft model
Ningbo Zhao, Hong Tang, Kai Yang & Dan Chen
Pages: 41-46
Published online: 23 Jan 2013
AbstractforCircadian rhythm characteristics of oral squamous cell carcinoma growth in an orthotopic xenograft model | Full Text | References | PDF (538.8 KB)
  • 97 Views
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Open Access
Article
Learning curve for endoscopic thyroidectomy: a single teaching hospital study
Feilin Cao, Ketao Jin, Binbin Cui & Bojian Xie
Pages: 47-52
Published online: 23 Jan 2013
AbstractforLearning curve for endoscopic thyroidectomy: a single teaching hospital study | Full Text | References | PDF (186.1 KB)
  • 58 Views
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Open Access
Article
Bevacizumab plus chemotherapy as salvage treatment in chemorefractory patients with metastatic colorectal cancer
Ravit Geva, Loredana Vecchione, Sabine Tejpar, Hubert Piessevaux, Eric Van Cutsem & Hans Prenen
Pages: 53-58
Published online: 25 Jan 2013
AbstractforBevacizumab plus chemotherapy as salvage treatment in chemorefractory patients with metastatic colorectal cancer | Full Text | References | PDF (177.5 KB)
  • 79 Views
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Open Access
Article
Stereotactic body radiation therapy via helical tomotherapy to replace brachytherapy for brachytherapy-unsuitable cervical cancer patients – a preliminary result
Chen-Hsi Hsieh, Hui-Ju Tien, Sheng-Mou Hsiao, Ming-Chow Wei, Wen-Yih Wu, Hsu-Dong Sun, Li-Ying Wang, Yen-Ping Hsieh, Yu-Jen Chen & Pei-Wei Shueng
Pages: 59-66
Published online: 29 Nov 2022
AbstractforStereotactic body radiation therapy via helical tomotherapy to replace brachytherapy for brachytherapy-unsuitable cervical cancer patients – a preliminary result | Full Text | References | PDF (167.7 KB)
  • 90 Views
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Open Access
Article
Clinical outcome observation of preoperative concurrent chemoradiotherapy/radiotherapy alone in 174 Chinese patients with local advanced cervical carcinoma
Li-Chun Wei, Ning Wang, Mei Shi, Jun-Yue Liu, Jian-Ping Li, Ying Zhang, Yan-Hong Huang, Xia Li & Yan Chen
Pages: 67-74
Published online: 07 Feb 2013
AbstractforClinical outcome observation of preoperative concurrent chemoradiotherapy/radiotherapy alone in 174 Chinese patients with local advanced cervical carcinoma | Full Text | References | PDF (1.6 MB)
  • 66 Views
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Open Access
Article
Arsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells
Saud Alarifi, Daoud Ali, Saad Alkahtani, Maqsood A Siddiqui & Bahy A Ali
Pages: 75-84
Published online: 29 Nov 2022
AbstractforArsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells | Full Text | References | PDF (1.3 MB)
  • 120 Views
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Open Access

Case Report

Case Report
The feasibility of a fiber optic laser approach to relieving lymphedematous syndrome: a case report
Beniamino Palmieri, Alessandro Di Cerbo, Valentina Rottigni, Gregorio Fistetto & Tommaso Iannitti
Pages: 85-88
Published online: 29 Nov 2022
AbstractforThe feasibility of a fiber optic laser approach to relieving lymphedematous syndrome: a case report | Full Text | References | PDF (921.9 KB)
  • 64 Views
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Open Access

Review

Review Article
Subcutaneous trastuzumab: development of a new formulation for treatment of HER2-positive early breast cancer
Salima Hamizi, Gilles Freyer, Naoual Bakrin, Emilie Henin, Amina Mohtaram, Olivia Le Saux & Claire Falandry
Pages: 89-94
Published online: 14 Feb 2013
AbstractforSubcutaneous trastuzumab: development of a new formulation for treatment of HER2-positive early breast cancer | Full Text | References | PDF (173.3 KB)
  • 182 Views
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Open Access

Case Report

Case Report
Molecular guided therapy for advanced pancreatic cancer patients with PI3K activated mutation: vision or illusion?
Anas Gazzah, Daniel Barrios Gonzales, Antonin Levy, Rastislav Bahleda, Michel Ducreux, Ludovic Lacroix & Jean Charles Soria
Pages: 95-97
Published online: 20 Feb 2013
AbstractforMolecular guided therapy for advanced pancreatic cancer patients with PI3K activated mutation: vision or illusion? | Full Text | References | PDF (125.6 KB)
  • 54 Views
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Open Access

Review

Review Article
Profile of bosutinib and its clinical potential in the treatment of chronic myeloid leukemia
Gunhild Keller-von Amsberg & Steffen Koschmieder
Pages: 99-106
Published online: 04 Mar 2013
AbstractforProfile of bosutinib and its clinical potential in the treatment of chronic myeloid leukemia | Full Text | References | PDF (234.6 KB)
  • 110 Views
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Open Access
Review Article
Palliative systemic therapy for women with recurrent epithelial ovarian cancer: current options
Laurie Elit & Hal Hirte
Pages: 107-118
Published online: 26 Feb 2013
AbstractforPalliative systemic therapy for women with recurrent epithelial ovarian cancer: current options | Full Text | References | PDF (538 KB)
  • 74 Views
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Open Access
Review Article
Minimally invasive esophagectomy for esophageal cancer in the People’s Republic of China: an overview
Chengchu Zhu & Ketao Jin
Pages: 119-124
Published online: 03 Mar 2013
AbstractforMinimally invasive esophagectomy for esophageal cancer in the People’s Republic of China: an overview | Full Text | References | PDF (445.7 KB)
  • 69 Views
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Open Access

Original Research

Article
Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer
Eftimia Boutsikou, Theodoros Kontakiotis, Paul Zarogoulidis, Kaid Darwiche, Ellada Eleptheriadou, Konstantinos Porpodis, Grammati Galaktidou, Leonidas Sakkas, Wolfgang Hohenforst-Schmidt, Kosmas Tsakiridis, Theodoros Karaiskos & Konstantinos Zarogoulidis
Pages: 125-134
Published online: 01 Mar 2013
AbstractforDocetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer | Full Text | References | PDF (681.6 KB)
  • 93 Views
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Open Access

Review

Review Article
Afatinib: emerging next-generation tyrosine kinase inhibitor for NSCLC
Valerie Nelson, Jacqueline Ziehr, Mark Agulnik & Melissa Johnson
Pages: 135-143
Published online: 05 Mar 2013
AbstractforAfatinib: emerging next-generation tyrosine kinase inhibitor for NSCLC | Full Text | References | PDF (275.2 KB)
  • 298 Views
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Open Access

Original Research

Article
Epigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling
Heiying Jin, Wei Gong, Chunxia Zhang & Shuiming Wang
Pages: 145-153
Published online: 08 Mar 2013
AbstractforEpigallocatechin gallate inhibits the proliferation of colorectal cancer cells by regulating Notch signaling | Full Text | References | PDF (453.1 KB)
  • 110 Views
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Open Access

Case Report

Case Report
Docetaxel for non-small-cell lung cancer harboring the activated EGFR mutation with T790M at initial presentation
Hiromichi Yamane, Nobuaki Ochi, Masayuki Yasugi, Takayuki Tabayashi, Tomoko Yamagishi, Yasumasa Monobe, Akiko Hisamoto, Katsuyuki Kiura & Nagio Takigawa
Pages: 155-160
Published online: 06 Mar 2013
AbstractforDocetaxel for non-small-cell lung cancer harboring the activated EGFR mutation with T790M at initial presentation | Full Text | References | PDF (1.6 MB)
  • 57 Views
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Open Access

Review

Review Article
Novel Bruton’s tyrosine kinase inhibitors currently in development
Osmond J D’Cruz & Fatih M Uckun
Pages: 161-176
Published online: 06 Mar 2013
AbstractforNovel Bruton’s tyrosine kinase inhibitors currently in development | Full Text | References | PDF (336.3 KB)
  • 106 Views
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Open Access

Original Research

Article
3′ untranslated region 1630 C>T polymorphism of prohibitin increases risk of breast cancer
Lin Tang, Yunzhao Zhao, Weiwei Nie, Zexing Wang & Xiaoxiang Guan
Pages: 177-182
Published online: 09 Mar 2013
Abstractfor3′ untranslated region 1630 C>T polymorphism of prohibitin increases risk of breast cancer | Full Text | References | PDF (360.5 KB)
  • 52 Views
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Open Access
Article
Expression of protein tyrosine kinase 6 (PTK6) in nonsmall cell lung cancer and their clinical and prognostic significance
Chao Zhao, Yan Chen, Weiwei Zhang, Jianrong Zhang, Yulian Xu, Wenjie Li, Sunxiao Chen & Anmei Deng
Pages: 183-188
Published online: 08 Mar 2013
AbstractforExpression of protein tyrosine kinase 6 (PTK6) in nonsmall cell lung cancer and their clinical and prognostic significance | Full Text | References | PDF (1.3 MB)
  • 83 Views
  • 2 CrossRef citations
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Open Access
Article
Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation
Yu Duan, Xin Zhao, Wei Ren, Xin Wang, Ke-Fu Yu, Dan Li, Xuan Zhang & Qiang Zhang
Pages: 189-198
Published online: 14 Mar 2013
AbstractforAntitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation | Full Text | References | PDF (3.2 MB)
  • 140 Views
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Open Access
Article
Dual control of Shuanghuang Shengbai granule on upstream and downstream signal modulators of CyclinD-CDK4/6 signaling pathway of cell cycle in Lewis-bearing mice with cyclophosphamide-induced myelosuppression
Xian Gu, Zhen-ye Xu, Ling-yu Zhu, Li-fang Wang, Kai Li & Qiang Pei
Pages: 199-209
Published online: 22 Mar 2013
AbstractforDual control of Shuanghuang Shengbai granule on upstream and downstream signal modulators of CyclinD-CDK4/6 signaling pathway of cell cycle in Lewis-bearing mice with cyclophosphamide-induced myelosuppression | Full Text | References | PDF (895.1 KB)
  • 75 Views
  • 5 CrossRef citations
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Open Access
Article
Preoperative neutrophil-lymphocyte and platelet-lymphocyte ratios as independent predictors of cervical stromal involvement in surgically treated endometrioid adenocarcinoma
Dan Wang, Jia-Xin Yang, Dong-Yan Cao, Xi-Run Wan, Feng-Zhi Feng, Hui-Fang Huang, Keng Shen & Yang Xiang
Pages: 211-216
Published online: 16 Mar 2013
AbstractforPreoperative neutrophil-lymphocyte and platelet-lymphocyte ratios as independent predictors of cervical stromal involvement in surgically treated endometrioid adenocarcinoma | Full Text | References | PDF (212.9 KB)
  • 95 Views
  • 27 CrossRef citations
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Open Access

Review

Review Article
Targeted treatment for advanced soft tissue sarcoma: profile of pazopanib
Rajeev Rajendra, Robin L Jones & Seth M Pollack
Pages: 217-222
Published online: 18 Mar 2013
AbstractforTargeted treatment for advanced soft tissue sarcoma: profile of pazopanib | Full Text | References | PDF (158.5 KB)
  • 80 Views
  • 5 CrossRef citations
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Open Access
Review Article
Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management
Allen S Ho, Sevin Turcan & Timothy A Chan
Pages: 223-232
Published online: 21 Mar 2013
AbstractforEpigenetic therapy: use of agents targeting deacetylation and methylation in cancer management | Full Text | References | PDF (1.1 MB)
  • 101 Views
  • 11 CrossRef citations
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Open Access

Case Report

Case Report
Syringocystadenoma papilliferum in the right lower abdomen: a case report and review of literature
Dong Xu, Tienan Bi, Huanrong Lan, Wenjie Yu, Wenmin Wang, Feilin Cao & Ketao Jin
Pages: 233-236
Published online: 26 Mar 2013
AbstractforSyringocystadenoma papilliferum in the right lower abdomen: a case report and review of literature | Full Text | References | PDF (644 KB)
  • 119 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Antitumor effects of inductive hyperthermia using magnetic ferucarbotran nanoparticles on human lung cancer xenografts in nude mice
Tomoyuki Araya, Kazuo Kasahara, Shingo Nishikawa, Hideharu Kimura, Takashi Sone, Hideo Nagae, Yoshio Ikehata, Isamu Nagano & Masaki Fujimura
Pages: 237-242
Published online: 24 Mar 2013
AbstractforAntitumor effects of inductive hyperthermia using magnetic ferucarbotran nanoparticles on human lung cancer xenografts in nude mice | Full Text | References | PDF (2.4 MB)
  • 103 Views
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Open Access

Review

Review Article
Targeting 20-HETE producing enzymes in cancer – rationale, pharmacology, and clinical potential
Anna Alexanian & Andrey Sorokin
Pages: 243-255
Published online: 26 Mar 2013
AbstractforTargeting 20-HETE producing enzymes in cancer – rationale, pharmacology, and clinical potential | Full Text | References | PDF (1.2 MB)
  • 150 Views
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Open Access
Review Article
Systematic review of dasatinib in chronic myeloid leukemia
Massimo Breccia, Adriano Salaroli, Matteo Molica & Giuliana Alimena
Pages: 257-265
Published online: 27 Mar 2013
AbstractforSystematic review of dasatinib in chronic myeloid leukemia | Full Text | References | PDF (194.4 KB)
  • 83 Views
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Open Access

Original Research

Article
Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors’ experience
Carlo Boselli, Claudio Renzi, Alessandro Gemini, Elisa Castellani, Stefano Trastulli, Jacopo Desiderio, Alessia Corsi, Francesco Barberini, Roberto Cirocchi, Alberto Santoro, Amilcare Parisi, Adriano Redler & Giuseppe Noya
Pages: 267-272
Published online: 27 Mar 2013
AbstractforSurgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors’ experience | Full Text | References | PDF (197.4 KB)
  • 54 Views
  • 6 CrossRef citations
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Open Access
Article
Combined measurement of CA 15-3 with novel autoantibodies improves diagnostic accuracy for breast cancer
Xuejun Dong, Mingfeng Yang, He Sun, Juan Lü, Zhuan Zheng, Zhiguo Li & Li Zhong
Pages: 273-279
Published online: 29 Nov 2022
AbstractforCombined measurement of CA 15-3 with novel autoantibodies improves diagnostic accuracy for breast cancer | Full Text | References | PDF (360.6 KB)
  • 80 Views
  • 6 CrossRef citations
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Open Access
Article
Association between the expression of four upregulated miRNAs and extrathyroidal invasion in papillary thyroid carcinoma
Zhihong Wang, Hao Zhang, Liang He, Wenwu Dong, Jing Li, Zhongyan Shan & Weiping Teng
Pages: 281-287
Published online: 29 Nov 2022
AbstractforAssociation between the expression of four upregulated miRNAs and extrathyroidal invasion in papillary thyroid carcinoma | Full Text | References | PDF (452.1 KB)
  • 62 Views
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Open Access

Review

Review Article
Improving survival and preventing recurrence of diffuse large B-cell lymphoma in younger patients: current strategies and future directions
Lionel Karlin & Bertrand Coiffier
Pages: 289-296
Published online: 29 Nov 2022
AbstractforImproving survival and preventing recurrence of diffuse large B-cell lymphoma in younger patients: current strategies and future directions | Full Text | References | PDF (233.2 KB)
  • 82 Views
  • 6 CrossRef citations
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Open Access

Original Research

Article
Treatment results of incomplete chemoradiotherapy in locally advanced cervical cancer
Ying Gao, Fei Gao, Zi Liu & Li-ping Song
Pages: 297-302
Published online: 02 Apr 2013
AbstractforTreatment results of incomplete chemoradiotherapy in locally advanced cervical cancer | Full Text | References | PDF (219.3 KB)
  • 56 Views
  • 3 CrossRef citations
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Open Access

Methodology

Article
Application of quantum dots as vectors in targeted survivin gene siRNA delivery
Jianjiang Zhao, Xiaoling Qiu, Zhiping Wang, Jie Pan, Jun Chen & Jiusong Han
Pages: 303-309
Published online: 03 Apr 2013
AbstractforApplication of quantum dots as vectors in targeted survivin gene siRNA delivery | Full Text | References | PDF (1.3 MB)
  • 74 Views
  • 24 CrossRef citations
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Open Access

Original Research

Article
Resting-state magnetoencephalography study of “small world” characteristics and cognitive dysfunction in patients with glioma
Xin-Hua Hu, Ting Lei, Hua-Zhong Xu, Yuan-Jie Zou & Hong-Yi Liu
Pages: 311-313
Published online: 03 Apr 2013
AbstractforResting-state magnetoencephalography study of “small world” characteristics and cognitive dysfunction in patients with glioma | Full Text | References | PDF (358 KB)
  • 60 Views
  • 5 CrossRef citations
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Open Access

Case Report

Case Report
Primary malignant fibrous histiocytoma of the breast: report of one case
Caigang Liu, Zuowei Zhao, Qingfu Zhang, Yunfei Wu & Feng Jin
Pages: 315-319
Published online: 29 Nov 2022
AbstractforPrimary malignant fibrous histiocytoma of the breast: report of one case | Full Text | References | PDF (1.7 MB)
  • 44 Views
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Open Access

Review

Review Article
Update of research on the role of EZH2 in cancer progression
Liang Shen, Jing Cui, Shumei Liang, Yingxin Pang & Peishu Liu
Pages: 321-324
Published online: 04 Apr 2013
AbstractforUpdate of research on the role of EZH2 in cancer progression | Full Text | References | PDF (147.2 KB)
  • 76 Views
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Open Access

Original Research

Article
A feasibility study of NIR fluorescent image-guided surgery in head and neck cancer based on the assessment of optimum surgical time as revealed through dynamic imaging
Junkichi Yokoyama, Mitsuhisa Fujimaki, Shinichi Ohba, Takashi Anzai, Ryota Yoshii, Shin Ito, Masataka Kojima & Katsuhisa Ikeda
Pages: 325-330
Published online: 08 Apr 2013
AbstractforA feasibility study of NIR fluorescent image-guided surgery in head and neck cancer based on the assessment of optimum surgical time as revealed through dynamic imaging | Full Text | References | PDF (2 MB)
  • 89 Views
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Open Access

Review

Review Article
A brief review of different types of sweat-gland carcinomas in the eyelid and orbit
Leilei Zhang, Shengfang Ge & Xianqun Fan
Pages: 331-340
Published online: 09 Apr 2013
AbstractforA brief review of different types of sweat-gland carcinomas in the eyelid and orbit | Full Text | References | PDF (212.6 KB)
  • 132 Views
  • 3 CrossRef citations
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Open Access

Original Research

Article
HER2-positive breast cancer patients receiving trastuzumab treatment obtain prognosis comparable with that of HER2-negative breast cancer patients
Tao Qin, Zhongyu Yuan, Roujun Peng, Bing Bai, Yanxia Shi, Xiaoyu Teng, Donggeng Liu & Shusen Wang
Pages: 341-347
Published online: 09 Apr 2013
AbstractforHER2-positive breast cancer patients receiving trastuzumab treatment obtain prognosis comparable with that of HER2-negative breast cancer patients | Full Text | References | PDF (217 KB)
  • 82 Views
  • 10 CrossRef citations
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Open Access
Article
MicroRNA-141 is downregulated in human renal cell carcinoma and regulates cell survival by targeting CDC25B
Xiu-yue Yu, Zhe Zhang, Jiao Liu, Bo Zhan & Chui-ze Kong
Pages: 349-354
Published online: 10 Apr 2013
AbstractforMicroRNA-141 is downregulated in human renal cell carcinoma and regulates cell survival by targeting CDC25B | Full Text | References | PDF (321.1 KB)
  • 64 Views
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Open Access

Case Report

Case Report
Laparoscopic partial nephrectomy of thyroid cancer metastasis: case report and review of the literature
Giovanni Cochetti, Efisio Puxeddu, Michele Del Zingaro, Francesco D’Amico, Emanuele Cottini, Francesco Barillaro & Ettore Mearini
Pages: 355-360
Published online: 10 Apr 2013
AbstractforLaparoscopic partial nephrectomy of thyroid cancer metastasis: case report and review of the literature | Full Text | References | PDF (2.6 MB)
  • 66 Views
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Open Access

Original Research

Article
Evaluation of the efficacy of a novel radical neck dissection preserving the external jugular vein, greater auricular nerve, and deep branches of the cervical nerve
Yadong Li, Jinsong Zhang & Kai Yang
Pages: 361-367
Published online: 10 Apr 2013
AbstractforEvaluation of the efficacy of a novel radical neck dissection preserving the external jugular vein, greater auricular nerve, and deep branches of the cervical nerve | Full Text | References | PDF (1.9 MB)
  • 69 Views
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Open Access

Corrigendum

Correction
Efficacy of sorafenib after liver transplantation in patients with primary hepatic carcinoma exceeding the Milan criteria: a preliminary study [Corrigendum]
Page: 369
Published online: 12 Apr 2013
CitationforEfficacy of sorafenib after liver transplantation in patients with primary hepatic carcinoma exceeding the Milan criteria: a preliminary study [Corrigendum] | Full Text | PDF (76.7 KB)
  • 41 Views
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Open Access

Review

Review Article
Bevacizumab in high-grade gliomas: a review of its uses, toxicity assessment, and future treatment challenges
Gazanfar Rahmathulla, Elizabeth J Hovey, Neda Hashemi-Sadraei & Manmeet S Ahluwalia
Pages: 371-389
Published online: 15 Apr 2013
AbstractforBevacizumab in high-grade gliomas: a review of its uses, toxicity assessment, and future treatment challenges | Full Text | References | PDF (1.5 MB)
  • 83 Views
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Open Access
Review Article
An update on the use of degarelix in the treatment of advanced hormone-dependent prostate cancer
Ferenc G Rick, Norman L Block & Andrew V Schally
Pages: 391-402
Published online: 16 Apr 2013
AbstractforAn update on the use of degarelix in the treatment of advanced hormone-dependent prostate cancer | Full Text | References | PDF (551.3 KB)
  • 208 Views
  • 28 CrossRef citations
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Open Access

Original Research

Article
Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21)
Afshin Amini, Anahid Ehteda, Samar Masoumi Moghaddam, Javed Akhter, Krishna Pillai & David Lawson Morris
Pages: 403-409
Published online: 16 Apr 2013
AbstractforCytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21) | Full Text | References | PDF (1.9 MB)
  • 185 Views
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Open Access
Article
RUNX3 gene promoter demethylation by 5-Aza-CdR induces apoptosis in breast cancer MCF-7 cell line
Hua-Feng Kang, Wang-Feng Lu, Xiao-Bin Ma, Xing Bao, Shuai Lin & Xi-Jing Wang
Pages: 411-417
Published online: 17 Apr 2013
AbstractforRUNX3 gene promoter demethylation by 5-Aza-CdR induces apoptosis in breast cancer MCF-7 cell line | Full Text | References | PDF (870.8 KB)
  • 49 Views
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Open Access
Article
Human telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment
Dawei Tian, Yan Sun, Yang Yang, Mingde Lei, Na Ding & Ruifa Han
Pages: 419-426
Published online: 18 Apr 2013
AbstractforHuman telomerase reverse-transcriptase promoter-controlled and herpes simplex virus thymidine kinase-armed adenoviruses for renal cell carcinoma treatment | Full Text | References | PDF (2.7 MB)
  • 75 Views
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Open Access

Review

Review Article
Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma
Hal W Hirte
Pages: 427-435
Published online: 18 Apr 2013
AbstractforProfile of erlotinib and its potential in the treatment of advanced ovarian carcinoma | Full Text | References | PDF (254.6 KB)
  • 72 Views
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Open Access

Original Research

Article
Immunomodulatory effects of the botanical compound LCS101: implications for cancer treatment
Itzchak H Rachmut, Noah Samuels, Steven J Melnick, Cheppail Ramachandran, Yedida Sharabi, Anya Pavlovsky, Yair Maimon & Jacob Shoham
Pages: 437-445
Published online: 24 Apr 2013
AbstractforImmunomodulatory effects of the botanical compound LCS101: implications for cancer treatment | Full Text | References | PDF (522.8 KB)
  • 79 Views
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Open Access
Article
Candidate cancer-targeting agents identified by expression-profiling arrays
Vittavat Termglinchan, Wachiraporn Wanichnopparat, Kulachanya Suwanwongse, Chunhakarn Teeyapant, Kanticha Chatpermporn, Kanchana Leerunyakul, Khwanruthai Chuadpia, Onpailin Sirimaneethum, Parinya Wijitworawong, Wattanakitch Mutirangura, Chatchawit Aporntewan, Chanida Vinayanuwattikun & Apiwat Mutirangura
Pages: 447-458
Published online: 23 Apr 2013
AbstractforCandidate cancer-targeting agents identified by expression-profiling arrays | Full Text | References | PDF (305.1 KB)
  • 62 Views
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Open Access

Review

Review Article
Updates on the diagnosis and treatment of intracranial nerve malignant peripheral nerve sheath tumors
Bénédicte L’Heureux-Lebeau & Issam Saliba
Pages: 459-470
Published online: 26 Apr 2013
AbstractforUpdates on the diagnosis and treatment of intracranial nerve malignant peripheral nerve sheath tumors | Full Text | References | PDF (352.3 KB)
  • 116 Views
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Open Access
Review Article
A review of the use of somatostatin analogs in oncology
Ozge Keskin & Suayib Yalcin
Pages: 471-483
Published online: 26 Apr 2013
AbstractforA review of the use of somatostatin analogs in oncology | Full Text | References | PDF (310.8 KB)
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Original Research

Article
Effect and safety of bevacizumab-containing chemotherapy treatment in Chinese patients with metastatic colorectal cancer
Qian Wu, Yan Shi, Li Chen, Xiaoyi Xiao & Guanghai Dai
Pages: 485-490
Published online: 30 Apr 2013
AbstractforEffect and safety of bevacizumab-containing chemotherapy treatment in Chinese patients with metastatic colorectal cancer | Full Text | References | PDF (194 KB)
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Article
Treatment outcome of advanced pancreatic cancer patients who are ineligible for a clinical trial
Akira Ueda, Ayumu Hosokawa, Kohei Ogawa, Hiroki Yoshita, Takayuki Ando, Shinya Kajiura, Haruka Fujinami, Kengo Kawai, Jun Nishikawa, Kazuto Tajiri, Masami Minemura & Toshiro Sugiyama
Pages: 491-496
Published online: 08 May 2013
AbstractforTreatment outcome of advanced pancreatic cancer patients who are ineligible for a clinical trial | Full Text | References | PDF (233.4 KB)
  • 53 Views
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Article
PIK3CA gene mutation associated with poor prognosis of lung adenocarcinoma
Lina Zhang, Lei Shi, Xiaoting Zhao, Yue Wang & Wentao Yue
Pages: 497-502
Published online: 07 May 2013
AbstractforPIK3CA gene mutation associated with poor prognosis of lung adenocarcinoma | Full Text | References | PDF (309.2 KB)
  • 117 Views
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Article
Antitumor effects and mechanisms of dendritic cells stimulated by sCD40L on ovarian cancer cells in vitro
Zheng-mao Zhang, Xue-mei Yang, Chao Zhang, Min-jie Zhang, Xia Li, Feng-hua Zhang, Shan Kang, Shi-jie Wang & Bao-en Shan
Pages: 503-515
Published online: 06 May 2013
AbstractforAntitumor effects and mechanisms of dendritic cells stimulated by sCD40L on ovarian cancer cells in vitro | Full Text | References | PDF (1.7 MB)
  • 55 Views
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Article
Cytoreductive surgery combined with hyperthermic intrapleural chemotherapy to treat thymoma or thymic carcinoma with pleural dissemination
Lei Yu, Yun Jing, Shan Ma, Fei Li & Yun-Feng Zhang
Pages: 517-521
Published online: 10 May 2013
AbstractforCytoreductive surgery combined with hyperthermic intrapleural chemotherapy to treat thymoma or thymic carcinoma with pleural dissemination | Full Text | References | PDF (986.2 KB)
  • 95 Views
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Rapid Communication

Article
Interleukin-12 prevents colorectal cancer liver metastases in mice
Fei Shen, Jiang-Lin Li, Weng-Song Cai, Guang-Hui Zhu, Wei-Li Gu, Lin Jia & Bo Xu
Pages: 523-526
Published online: 13 May 2013
AbstractforInterleukin-12 prevents colorectal cancer liver metastases in mice | Full Text | References | PDF (614.7 KB)
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Original Research

Article
Type 1 insulin-like growth factor receptor monoclonal antibody (HX-1162) treatment for liver cancer
Xue-Hui Chen, Zhi-Qiang Li, Hua Peng, Su-Mei Jin, Hui-Qing Fu, Tie-Chui Zhu & Xiao-Gang Weng
Pages: 527-530
Published online: 14 May 2013
AbstractforType 1 insulin-like growth factor receptor monoclonal antibody (HX-1162) treatment for liver cancer | Full Text | References | PDF (173.2 KB)
  • 47 Views
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Article
Pomalidomide: a novel drug to treat relapsed and refractory multiple myeloma
Evangelos Terpos, Nikolaos Kanellias, Dimitrios Christoulas, Efstathios Kastritis & Meletios A Dimopoulos
Pages: 531-538
Published online: 10 May 2013
AbstractforPomalidomide: a novel drug to treat relapsed and refractory multiple myeloma | Full Text | References | PDF (205.5 KB)
  • 144 Views
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Article
New dilemmas in small-cell lung cancer TNM clinical staging
Konstantinos Zarogoulidis, Dimitrios Latsios, Konstantinos Porpodis, Paul Zarogoulidis, Kaid Darwiche, Nick Antoniou, Wolfgang Hohenforst-Schmidt, Ellada Eleftheriadou, Efimia Boutsikou & Theodoros Kontakiotis
Pages: 539-547
Published online: 16 May 2013
AbstractforNew dilemmas in small-cell lung cancer TNM clinical staging | Full Text | References | PDF (690.6 KB)
  • 61 Views
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Article
Dose-effect relationship of CpG oligodeoxyribonucleotide 1826 in murine Lewis lung cancer treated with irradiation
Xibing Zhuang, Tiankui Qiao, Sujuan Yuan, Wei Chen, Lin Zha & Li Yan
Pages: 549-554
Published online: 29 Nov 2022
AbstractforDose-effect relationship of CpG oligodeoxyribonucleotide 1826 in murine Lewis lung cancer treated with irradiation | Full Text | References | PDF (678.8 KB)
  • 55 Views
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Article
Abundance of Flt3 and its ligand in astrocytic tumors
C Eßbach, N Andrae, D Pachow, J-P Warnke, A Wilisch-Neumann, E Kirches & C Mawrin
Pages: 555-561
Published online: 24 May 2013
AbstractforAbundance of Flt3 and its ligand in astrocytic tumors | Full Text | References | PDF (1 MB)
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Review

Review Article
Novel small molecule EGFR inhibitors as candidate drugs in non-small cell lung cancer
Rossana Berardi, Matteo Santoni, Francesca Morgese, Zelmira Ballatore, Agnese Savini, Azzurra Onofri, Paola Mazzanti, Mirco Pistelli, Chiara Pierantoni, Mariagrazia De Lisa, Miriam Caramanti, Silvia Pagliaretta, Chiara Pellei & Stefano Cascinu
Pages: 563-576
Published online: 21 May 2013
AbstractforNovel small molecule EGFR inhibitors as candidate drugs in non-small cell lung cancer | Full Text | References | PDF (629.8 KB)
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Original Research

Article
Circulating microRNA-122a as a diagnostic marker for hepatocellular carcinoma
Jie Luo, Ming Chen, Hengliu Huang, Tao Yuan, Mingxu Zhang, Kejun Zhang & Shaoli Deng
Pages: 577-583
Published online: 22 May 2013
AbstractforCirculating microRNA-122a as a diagnostic marker for hepatocellular carcinoma | Full Text | References | PDF (248.4 KB)
  • 92 Views
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Article
Nanoparticle albumin-bound paclitaxel combined with cisplatin as the first-line treatment for metastatic esophageal squamous cell carcinoma
Yan Shi, Rui Qin, Zhi-Kuan Wang & Guang-Hai Dai
Pages: 585-591
Published online: 27 May 2013
AbstractforNanoparticle albumin-bound paclitaxel combined with cisplatin as the first-line treatment for metastatic esophageal squamous cell carcinoma | Full Text | References | PDF (235.8 KB)
  • 93 Views
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Review

Review Article
Telangiectatic osteosarcoma: a review of literature
Jun-jian Liu, Shen Liu, Jian-guang Wang, Wei Zhu, Ying-qi Hua, Wei Sun & Zheng-dong Cai
Pages: 593-602
Published online: 28 May 2013
AbstractforTelangiectatic osteosarcoma: a review of literature | Full Text | References | PDF (190.6 KB)
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Original Research

Article
The different radiosensitivity when combining erlotinib with radiation at different administration schedules might be related to activity variations in c-MET-PI3K-AKT signal transduction
Hong-Qing Zhuang, Qi-Fu Bo, Zhi-Yong Yuan, Jun Wang, Lu-Jun Zhao & Ping Wang
Pages: 603-608
Published online: 28 May 2013
AbstractforThe different radiosensitivity when combining erlotinib with radiation at different administration schedules might be related to activity variations in c-MET-PI3K-AKT signal transduction | Full Text | References | PDF (955.4 KB)
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Article
Measurement of exhaled alveolar nitrogen oxide in patients with lung cancer: a friend from the past still precious today
Anastasios Kallianos, Sotirios Tsimpoukis, Paul Zarogoulidis, Kaid Darwiche, Andriani Charpidou, Ilias Tsioulis, Georgia Trakada, Konstantinos Porpodis, Dionysios Spyratos, Athanasios Panoutsopoulos, Lemonia Veletza, Konstantinos Kostopoulos, Charalampos Kostopoulos, Ilias Karapantzos, Kosmas Tsakiridis, Wolfgang Hohenforst-Schmidt, Konstantinos Zarogoulidis, Aggeliki Rapti & Konstantinos Syrigos
Pages: 609-613
Published online: 31 May 2013
AbstractforMeasurement of exhaled alveolar nitrogen oxide in patients with lung cancer: a friend from the past still precious today | Full Text | References | PDF (153.6 KB)
  • 63 Views
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Short Report

Article
Increased CD70 expression is associated with clinical resistance to cisplatin-based chemotherapy and poor survival in advanced ovarian carcinomas
Naifu Liu, Xiugui Sheng, Yi Liu, Xiaoling Zhang & Jinming Yu
Pages: 615-619
Published online: 29 Nov 2022
AbstractforIncreased CD70 expression is associated with clinical resistance to cisplatin-based chemotherapy and poor survival in advanced ovarian carcinomas | Full Text | References | PDF (1.5 MB)
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Original Research

Article
Investigation of prognostic significance of CD109 expression in women with vulvar squamous cell carcinoma
Pelin Özün Özbay, Tekin Ekinci, Seyran Yiǧit, Ali Yavuzcan, Selda Uysal, Ferit Soylu & Fulya Cakalagaoglu
Pages: 621-627
Published online: 07 Jun 2013
AbstractforInvestigation of prognostic significance of CD109 expression in women with vulvar squamous cell carcinoma | Full Text | References | PDF (1.3 MB)
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Review

Review Article
Nanomaterials in the application of tumor vaccines: advantages and disadvantages
XD Li, JY Gao, Y Yang, HY Fang, YJ Han, XM Wang & W Ge
Pages: 629-634
Published online: 05 Jun 2013
AbstractforNanomaterials in the application of tumor vaccines: advantages and disadvantages | Full Text | References | PDF (146.5 KB)
  • 185 Views
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Review Article
Current management options for recurrent adrenocortical carcinoma
Anthony R Glover, Julian C Y Ip, Jing Ting Zhao, Patsy S H Soon, Bruce G Robinson & Stan B Sidhu
Pages: 635-643
Published online: 06 Jun 2013
AbstractforCurrent management options for recurrent adrenocortical carcinoma | Full Text | References | PDF (214.5 KB)
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Original Research

Article
Long-term results of a randomized controlled trial evaluating preoperative chemotherapy in resectable non-small cell lung cancer
Zhiwei Chen, Hong Jian, Zhen Zhou, Baijun Cheng, Shun Lu & Meilin Liao
Pages: 645-650
Published online: 07 Jun 2013
AbstractforLong-term results of a randomized controlled trial evaluating preoperative chemotherapy in resectable non-small cell lung cancer | Full Text | References | PDF (212.4 KB)
  • 67 Views
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Expert Opinion

Article
Current treatment options for management of anal intraepithelial neoplasia
Stephen E Weis
Pages: 651-665
Published online: 10 Jun 2013
AbstractforCurrent treatment options for management of anal intraepithelial neoplasia | Full Text | References | PDF (1.6 MB)
  • 157 Views
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Original Research

Article
Cyclin D1 affects epithelial–mesenchymal transition in epithelial ovarian cancer stem cell-like cells
Jie Jiao, Lu Huang, Feng Ye, MinFeng Shi, XiaoDong Cheng, XinYu Wang, DongXiao Hu, Xing Xie & WeiGuo Lu
Pages: 667-677
Published online: 20 Jun 2013
AbstractforCyclin D1 affects epithelial–mesenchymal transition in epithelial ovarian cancer stem cell-like cells | Full Text | References | PDF (1.3 MB)
  • 69 Views
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Review

Review Article
Prognostic biomarkers for patients with advanced renal cell carcinoma treated with VEGF-targeted tyrosine kinase inhibitors
Daniel C Cho
Pages: 679-684
Published online: 29 Nov 2022
AbstractforPrognostic biomarkers for patients with advanced renal cell carcinoma treated with VEGF-targeted tyrosine kinase inhibitors | Full Text | References | PDF (148.4 KB)
  • 53 Views
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Original Research

Article
Preliminary study of CT in combination with MRI perfusion imaging to assess hemodynamic changes during angiogenesis in a rabbit model of lung cancer
Qiang Zhang, Baoqi Shi, Zhaoxin Liu, Mingmin Zhang & Weijing Zhang
Pages: 685-692
Published online: 17 Jun 2013
AbstractforPreliminary study of CT in combination with MRI perfusion imaging to assess hemodynamic changes during angiogenesis in a rabbit model of lung cancer | Full Text | References | PDF (1.5 MB)
  • 54 Views
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Article
Human epidermal growth factor receptor 2-positive breast cancer: which cytotoxic agent best complements trastuzumab’s efficacy in vitro?
Tracey Hurrell & Kim Outhoff
Pages: 693-701
Published online: 29 Nov 2022
AbstractforHuman epidermal growth factor receptor 2-positive breast cancer: which cytotoxic agent best complements trastuzumab’s efficacy in vitro? | Full Text | References | PDF (1.6 MB)
  • 72 Views
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Case Report

Case Report
Fatal bleeding in a nasopharyngeal carcinoma patient after concurrent chemoradiation plus cetuximab: a case report
LingYan Zheng, SenXiang Yan, DanFang Yan, JingSong Yang & YiXiang Wang
Pages: 703-706
Published online: 29 Nov 2022
AbstractforFatal bleeding in a nasopharyngeal carcinoma patient after concurrent chemoradiation plus cetuximab: a case report | Full Text | References | PDF (628.9 KB)
  • 61 Views
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Case Report
Primary primitive neuroectodermal tumor of the cervix
Bo Li, Ling Ouyang, Xue Han, Yang Zhou, Xin Tong, Shulang Zhang & Qingfu Zhang
Pages: 707-711
Published online: 17 Jun 2013
AbstractforPrimary primitive neuroectodermal tumor of the cervix | Full Text | References | PDF (1.6 MB)
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Original Research

Article
Aberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma
Viviane Sonaglio, Ana C de Carvalho, Silvia R C Toledo, Carolina Salinas-Souza, André L Carvalho, Antonio S Petrilli, Beatriz de Camargo & André L Vettore
Pages: 713-723
Published online: 17 Jun 2013
AbstractforAberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma | Full Text | References | PDF (1.2 MB)
  • 77 Views
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Article
Androgen-deprivation therapy versus radical prostatectomy as monotherapy among clinically localized prostate cancer patients
Jinan Liu, Lizheng Shi, Oliver Sartor & Richard Culbertson
Pages: 725-732
Published online: 17 Jun 2013
AbstractforAndrogen-deprivation therapy versus radical prostatectomy as monotherapy among clinically localized prostate cancer patients | Full Text | References | PDF (297 KB)
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Article
Inhibition of leukemic cells by valproic acid, an HDAC inhibitor, in xenograft tumors
Zhihua Zhang, Changlai Hao, Lihong Wang, Peng Liu, Lei Zhao, Cuimin Zhu & Xia Tian
Pages: 733-740
Published online: 18 Jun 2013
AbstractforInhibition of leukemic cells by valproic acid, an HDAC inhibitor, in xenograft tumors | Full Text | References | PDF (1.3 MB)
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Article
Pretreatment long interspersed element (LINE)-1 methylation levels, not early hypomethylation under treatment, predict hematological response to azacitidine in elderly patients with acute myeloid leukemia
Michael Cross, Enrica Bach, Thao Tran, Rainer Krahl, Nadja Jaekel, Dietger Niederwieser, Christian Junghanss, Georg Maschmeyer & Haifa Kathrin Al-Ali
Pages: 741-748
Published online: 20 Jun 2013
AbstractforPretreatment long interspersed element (LINE)-1 methylation levels, not early hypomethylation under treatment, predict hematological response to azacitidine in elderly patients with acute myeloid leukemia | Full Text | References | PDF (269.1 KB)
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Case Report

Case Report
Malignant thrombosis of the superior vena cava caused by non-small-cell lung cancer treated with radiation and erlotinib: a case with complete and prolonged response over 3 years
Jianyang Wang, Jun Liang, Wenqing Wang, Han Ouyang & Luhua Wang
Pages: 749-753
Published online: 01 Jul 2013
AbstractforMalignant thrombosis of the superior vena cava caused by non-small-cell lung cancer treated with radiation and erlotinib: a case with complete and prolonged response over 3 years | Full Text | References | PDF (1.4 MB)
  • 90 Views
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Case Report
Orthotopic liver transplantation after the combined use of locoregional therapy and sorafenib for advanced hepatocellular carcinoma
Eun Jin Yoo, Hye Sun Shin, Seung Up Kim, Dong Jin Joo, Jun Yong Park, Gi Hong Choi, Do Young Kim, Sang Hoon Ahn, Jinsil Seong, Myung Joo Koh, Kwang-Hyub Han & Chae Yoon Chon
Pages: 755-759
Published online: 21 Jun 2013
AbstractforOrthotopic liver transplantation after the combined use of locoregional therapy and sorafenib for advanced hepatocellular carcinoma | Full Text | References | PDF (642.3 KB)
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Original Research

Article
Efficacy of intraarterial chemoinfusion therapy for locally advanced breast cancer patients: a retrospective analysis of 28 cases
Wei Zhang, Rong Liu, Yingying Wang, Sheng Qian, Jianhua Wang, Zhiping Yan & Hongwei Zhang
Pages: 761-765
Published online: 25 Jun 2013
AbstractforEfficacy of intraarterial chemoinfusion therapy for locally advanced breast cancer patients: a retrospective analysis of 28 cases | Full Text | References | PDF (1.3 MB)
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Perspectives

Article
Drugs for solid cancer: the productivity crisis prompts a rethink
Daniel Rösel, Jan Brábek, Pavel Veselý & Michael Fernandes
Pages: 767-777
Published online: 26 Jun 2013
AbstractforDrugs for solid cancer: the productivity crisis prompts a rethink | Full Text | References | PDF (2.1 MB)
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Original Research

Article
Apoptosis and G2/M arrest induced by Allium ursinum (ramson) watery extract in an AGS gastric cancer cell line
Xiao-yan Xu, Guo-qing Song, Yan-qiu Yu, Hai-ying Ma, Ling Ma & Yu-nan Jin
Pages: 779-783
Published online: 25 Jun 2013
AbstractforApoptosis and G2/M arrest induced by Allium ursinum (ramson) watery extract in an AGS gastric cancer cell line | Full Text | References | PDF (1.2 MB)
  • 99 Views
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Review

Review Article
Potential use of custirsen to treat prostate cancer
Celestia S Higano
Pages: 785-797
Published online: 25 Jun 2013
AbstractforPotential use of custirsen to treat prostate cancer | Full Text | References | PDF (925.5 KB)
  • 69 Views
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Case Series

Long term results of sentinel lymph node biopsy in early oral squamous cell carcinoma
Didier Dequanter, Mohammad Shahla, Pascal Paulus & Philippe Lothaire
Pages: 799-802
Published online: 25 Jun 2013
AbstractforLong term results of sentinel lymph node biopsy in early oral squamous cell carcinoma | Full Text | References | PDF (135.6 KB)
  • 53 Views
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Original Research

Article
Comparative study analyzing survival and safety of bevacizumab/carboplatin/paclitaxel and cisplatin/pemetrexed in chemotherapy-naïve patients with advanced non-squamous bronchogenic carcinoma not harboring EGFR mutation
Yasser Abdel Kader, Thierry Le Chevalier, Tamer El-Nahas & Amr Sakr
Pages: 803-809
Published online: 01 Jul 2013
AbstractforComparative study analyzing survival and safety of bevacizumab/carboplatin/paclitaxel and cisplatin/pemetrexed in chemotherapy-naïve patients with advanced non-squamous bronchogenic carcinoma not harboring EGFR mutation | Full Text | References | PDF (359.1 KB)
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Article
Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment
Hongyun Zhao, Yuanyuan Zhao, Ying Guo, Yan Huang, Suxia Lin, Cong Xue, Fei Xu, Yang Zhang, Liping Zhao, Zhihuang Hu & Li Zhang
Pages: 811-818
Published online: 03 Jul 2013
AbstractforClinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment | Full Text | References | PDF (283.1 KB)
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Review

Review Article
Circulating nucleic acids in plasma and serum (CNAPS): applications in oncology
José A González-Masiá, Damián García-Olmo & Dolores C García-Olmo
Pages: 819-832
Published online: 08 Jul 2013
AbstractforCirculating nucleic acids in plasma and serum (CNAPS): applications in oncology | Full Text | References | PDF (551.6 KB)
  • 118 Views
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Original Research

Article
MicroRNA-145 downregulation associates with advanced tumor progression and poor prognosis in patients suffering osteosarcoma
Mingjie Tang, Lijun Lin, Haikang Cai, Jie Tang & Zubin Zhou
Pages: 833-838
Published online: 08 Jul 2013
AbstractforMicroRNA-145 downregulation associates with advanced tumor progression and poor prognosis in patients suffering osteosarcoma | Full Text | References | PDF (507.2 KB)
  • 60 Views
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Review

Review Article
Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer
Gordana Maric, April AN Rose, Matthew G Annis & Peter M Siegel
Pages: 839-852
Published online: 09 Jul 2013
AbstractforGlycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer | Full Text | References | PDF (693.6 KB)
  • 276 Views
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Original Research

Article
Evaluation of host quality of life and immune function in breast cancer patients treated with combination of adjuvant chemotherapy and oral administration of Lentinula edodes mycelia extract
Yukiko Nagashima, Noriko Maeda, Shigeru Yamamoto, Shigefumi Yoshino & Masaaki Oka
Pages: 853-859
Published online: 09 Jul 2013
AbstractforEvaluation of host quality of life and immune function in breast cancer patients treated with combination of adjuvant chemotherapy and oral administration of Lentinula edodes mycelia extract | Full Text | References | PDF (282 KB)
  • 108 Views
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Article
Combined use of cyclophosphamide and Chalone 19-peptide in experimental breast cancer
Yuanxi Huang, Yan He, Shengqian Ye, Xiaomei Li, Qingqi Zhong, Zhuo Chen & Xiaoming Jin
Pages: 861-867
Published online: 29 Nov 2022
AbstractforCombined use of cyclophosphamide and Chalone 19-peptide in experimental breast cancer | Full Text | References | PDF (4 MB)
  • 57 Views
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Article
Clinical significance of B7-H4 expression in matched non-small cell lung cancer brain metastases and primary tumors
Zhen-ye Li, Xiang-heng Zhang, Yu Chen, Jian-gui Guo, Ke Sai, Qun-ying Yang, Zhong-ping Chen & Yong-gao Mou
Pages: 869-875
Published online: 10 Jul 2013
AbstractforClinical significance of B7-H4 expression in matched non-small cell lung cancer brain metastases and primary tumors | Full Text | References | PDF (1.3 MB)
  • 73 Views
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Article
A miR-SNP of the XPO5 gene is associated with advanced non-small-cell lung cancer
Cuimin Ding, Cuiqiao Li, Hongjing Wang, Bin Li & Zhanjun Guo
Pages: 877-881
Published online: 29 Nov 2022
AbstractforA miR-SNP of the XPO5 gene is associated with advanced non-small-cell lung cancer | Full Text | References | PDF (198.1 KB)
  • 80 Views
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Article
Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer
Rong-Zhen Luo, Zhong-Yu Yuan, Mei Li, Shao-Yan Xi, Jia Fu & Jiehua He
Pages: 883-888
Published online: 19 Jul 2013
AbstractforAccumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer | Full Text | References | PDF (511.9 KB)
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Review

Review Article
Current status of bevacizumab in advanced ovarian cancer
Federica Tomao, Anselmo Papa, Luigi Rossi, Davide Caruso, Pierluigi Benedetti Panici, Martina Venezia & Silverio Tomao
Pages: 889-899
Published online: 22 Jul 2013
AbstractforCurrent status of bevacizumab in advanced ovarian cancer | Full Text | References | PDF (346.6 KB)
  • 83 Views
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Original Research

Article
Analysis of the antitumor activity of gemcitabine and carboplatin against ovarian clear-cell carcinoma using the DNA damage marker γH2AX
Eriko Takatori, Tadahiro Shoji, Takashi Sawai, Akira Kurose & Toru Sugiyama
Pages: 901-907
Published online: 17 Jul 2013
AbstractforAnalysis of the antitumor activity of gemcitabine and carboplatin against ovarian clear-cell carcinoma using the DNA damage marker γH2AX | Full Text | References | PDF (1.4 MB)
  • 67 Views
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Review

Review Article
The emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective
Lorenzo Montanaro, Davide Treré & Massimo Derenzini
Pages: 909-916
Published online: 19 Jul 2013
AbstractforThe emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective | Full Text | References | PDF (597 KB)
  • 62 Views
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Original Research

Article
Comparison of imaging-based gross tumor volume and pathological volume determined by whole-mount serial sections in primary cervical cancer
Ying Zhang, Jing Hu, Jianping Li, Ning Wang, Weiwei Li, Yongchun Zhou, Junyue Liu, Lichun Wei, Mei Shi, Shengjun Wang, Jing Wang, Xia Li & Wanling Ma
Pages: 917-923
Published online: 19 Jul 2013
AbstractforComparison of imaging-based gross tumor volume and pathological volume determined by whole-mount serial sections in primary cervical cancer | Full Text | References | PDF (1.2 MB)
  • 66 Views
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Article
Results of a randomized and controlled clinical trial evaluating the efficacy and safety of combination therapy with Endostar and S-1 combined with oxaliplatin in advanced gastric cancer
Rong Xu, Fang Wang, Lei Ma, Rui Chen, Ru Chen, Mijiti Kebinu, Lili Ma, Zhongcheng Han, Ayixiamu, Mahemiti Mayier, Pengcheng Su, Yiming Naman, Haliyazimu Jieensi, Haixuan Yang, Abulizi Adili, Saiding Aili & Jiang Liu
Pages: 925-929
Published online: 25 Jul 2013
AbstractforResults of a randomized and controlled clinical trial evaluating the efficacy and safety of combination therapy with Endostar and S-1 combined with oxaliplatin in advanced gastric cancer | Full Text | References | PDF (195.8 KB)
  • 60 Views
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Review

Review Article
Nimotuzumab as a radiosensitizing agent in the treatment of high grade glioma: challenges and opportunities
Arlhee Diaz-Miqueli & Giselle Saurez Martinez
Pages: 931-942
Published online: 24 Jul 2013
AbstractforNimotuzumab as a radiosensitizing agent in the treatment of high grade glioma: challenges and opportunities | Full Text | References | PDF (974.2 KB)
  • 81 Views
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Review Article
Gamma secretase inhibitors of Notch signaling
Roma Olsauskas-Kuprys, Andrei Zlobin & Clodia Osipo
Pages: 943-955
Published online: 23 Jul 2013
AbstractforGamma secretase inhibitors of Notch signaling | Full Text | References | PDF (657.4 KB)
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Review Article
Clinical value of serum human epididymis protein 4 assay in the diagnosis of ovarian cancer: a meta-analysis
Zhijun Yang, Zhaoqing Luo & Li Li
Pages: 957-966
Published online: 23 Jul 2013
AbstractforClinical value of serum human epididymis protein 4 assay in the diagnosis of ovarian cancer: a meta-analysis | Full Text | References | PDF (597.1 KB)
  • 63 Views
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Original Research

Article
Overexpression of epidermal growth factor receptor as a prognostic factor in colorectal cancer on the basis of the Allred scoring system
Marta Rokita, Rafał Stec, Lubomir Bodnar, Radosław Charkiewicz, Jan Korniluk, Marta Smoter, Marzena Cichowicz, Lech Chyczewski, Jacek Nikliński, Wojciech Kozłowski & Cezary Szczylik
Pages: 967-976
Published online: 24 Jul 2013
AbstractforOverexpression of epidermal growth factor receptor as a prognostic factor in colorectal cancer on the basis of the Allred scoring system | Full Text | References | PDF (313.5 KB)
  • 81 Views
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Open Access
Article
The role of fluorescence diagnosis in clinical practice
Aleksander Sieroń, Karolina Sieroń-Stołtny, Aleksandra Kawczyk-Krupka, Wojciech Latos, Sebastian Kwiatek, Dariusz Straszak & Andrzej M Bugaj
Pages: 977-982
Published online: 24 Jul 2013
AbstractforThe role of fluorescence diagnosis in clinical practice | Full Text | References | PDF (2.4 MB)
  • 168 Views
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Article
Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells
Ying-Hui Chen, Jo-Yu Wang, Bo-Syong Pan, Yi-Fen Mu, Meng-Shao Lai, Edmund Cheung So, Thian-Sze Wong & Bu-Miin Huang
Pages: 983-998
Published online: 25 Jul 2013
AbstractforCordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells | Full Text | References | PDF (2.5 MB)
  • 97 Views
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Review

Review Article
Critical analysis of the potential for targeting STAT3 in human malignancy
Noah D Peyser & Jennifer R Grandis
Pages: 999-1010
Published online: 30 Jul 2013
AbstractforCritical analysis of the potential for targeting STAT3 in human malignancy | Full Text | References | PDF (246.1 KB)
  • 60 Views
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Review Article
Update on imatinib for gastrointestinal stromal tumors: duration of treatment
Mark Linch, Jeroen Claus & Charlotte Benson
Pages: 1011-1023
Published online: 30 Jul 2013
AbstractforUpdate on imatinib for gastrointestinal stromal tumors: duration of treatment | Full Text | References | PDF (806.7 KB)
  • 85 Views
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Original Research

Article
Effect of transarterial chemoembolization with miriplatin plus epirubicin on local control of hepatocellular carcinoma: a retrospective comparison with miriplatin monotherapy
Naoko Hashimoto, Jin Iwazawa, Shoichi Ohue & Takashi Mitani
Pages: 1025-1030
Published online: 29 Nov 2022
AbstractforEffect of transarterial chemoembolization with miriplatin plus epirubicin on local control of hepatocellular carcinoma: a retrospective comparison with miriplatin monotherapy | Full Text | References | PDF (239.7 KB)
  • 54 Views
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Review

Review Article
Update on oncolytic viral therapy – targeting angiogenesis
James R Tysome, Nick R Lemoine & Yaohe Wang
Pages: 1031-1040
Published online: 31 Jul 2013
AbstractforUpdate on oncolytic viral therapy – targeting angiogenesis | Full Text | References | PDF (229.3 KB)
  • 81 Views
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Original Research

Article
Single nucleotide polymorphisms in the mitochondrial displacement loop and age at onset of non-Hodgkin lymphoma
Haiyan Fan, Cuiju Wang & Zhanjun Guo
Pages: 1041-1045
Published online: 02 Aug 2013
AbstractforSingle nucleotide polymorphisms in the mitochondrial displacement loop and age at onset of non-Hodgkin lymphoma | Full Text | References | PDF (244.6 KB)
  • 50 Views
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Open Access
Article
Activation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1–6 cells
Kuo-Shyang Jeng, I-Shyan Sheen, Wen-Juei Jeng, Ming-Che Yu, Hsin-I Hsiau, Fang-Yu Chang & Hsin-Hua Tsai
Pages: 1047-1055
Published online: 05 Aug 2013
AbstractforActivation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1–6 cells | Full Text | References | PDF (1.5 MB)
  • 87 Views
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Open Access
Article
454 next generation-sequencing outperforms allele-specific PCR, Sanger sequencing, and pyrosequencing for routine KRAS mutation analysis of formalin-fixed, paraffin-embedded samples
Annalisa Altimari, Dario de Biase, Giovanna De Maglio, Elisa Gruppioni, Elisa Capizzi, Alessio Degiovanni, Antonia D’Errico, Annalisa Pession, Stefano Pizzolitto, Michelangelo Fiorentino & Giovanni Tallini
Pages: 1057-1064
Published online: 29 Nov 2022
Abstractfor454 next generation-sequencing outperforms allele-specific PCR, Sanger sequencing, and pyrosequencing for routine KRAS mutation analysis of formalin-fixed, paraffin-embedded samples | Full Text | References | PDF (222.2 KB)
  • 204 Views
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Article
Human epidermal growth factor receptor-2 overexpression and amplification in metastatic and recurrent high grade or type 2 endometrial carcinomas
Rina Kato, Kiyoshi Hasegawa, Risa Ishii, Akiko Owaki, Yutaka Torii, Shuko Oe, Hiroshi Hirasawa, Yoichi Kobayashi & Yasuhiro Udagawa
Pages: 1065-1071
Published online: 07 Aug 2013
AbstractforHuman epidermal growth factor receptor-2 overexpression and amplification in metastatic and recurrent high grade or type 2 endometrial carcinomas | Full Text | References | PDF (753.5 KB)
  • 50 Views
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Open Access
Article
Adjuvant chemotherapy for luminal A breast cancer: a prospective study comparing two popular chemotherapy regimens
Yasser Abdel Kader, Tamer El-Nahas & Amr Sakr
Pages: 1073-1077
Published online: 09 Aug 2013
AbstractforAdjuvant chemotherapy for luminal A breast cancer: a prospective study comparing two popular chemotherapy regimens | Full Text | References | PDF (787.7 KB)
  • 107 Views
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Review

Review Article
Combining molecular targeted agents with radiation therapy for malignant gliomas
Claudia Scaringi, Riccardo Maurizi Enrici & Giuseppe Minniti
Pages: 1079-1095
Published online: 09 Aug 2013
AbstractforCombining molecular targeted agents with radiation therapy for malignant gliomas | Full Text | References | PDF (1.2 MB)
  • 63 Views
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Review Article
Future directions in combined modality therapy for rectal cancer: reevaluating the role of total mesorectal excision after chemoradiotherapy
Abhishek A Solanki, Daniel T Chang & Stanley L Liauw
Pages: 1097-1110
Published online: 29 Nov 2022
AbstractforFuture directions in combined modality therapy for rectal cancer: reevaluating the role of total mesorectal excision after chemoradiotherapy | Full Text | References | PDF (647.7 KB)
  • 51 Views
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Review Article
Potential of ponatinib to treat chronic myeloid leukemia and acute lymphoblastic leukemia
Kimberly E Price, Najma Saleem, Georgina Lee & Michael Steinberg
Pages: 1111-1118
Published online: 20 Aug 2013
AbstractforPotential of ponatinib to treat chronic myeloid leukemia and acute lymphoblastic leukemia | Full Text | References | PDF (221 KB)
  • 166 Views
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Original Research

Article
Influence of the oncolytic parvovirus H-1, CTLA-4 antibody tremelimumab and cytostatic drugs on the human immune system in a human in vitro model of colorectal cancer cells
Bernd Heinrich, Katrin Goepfert, Maike Delic, Peter R Galle & Markus Moehler
Pages: 1119-1127
Published online: 29 Nov 2022
AbstractforInfluence of the oncolytic parvovirus H-1, CTLA-4 antibody tremelimumab and cytostatic drugs on the human immune system in a human in vitro model of colorectal cancer cells | Full Text | References | PDF (340.2 KB)
  • 81 Views
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Open Access
Article
Arsenic trioxide inhibits viability of pancreatic cancer stem cells in culture and in a xenograft model via binding to SHH-Gli
Jin-bin Han, Feng Sang, Jin-jia Chang, Yong-qiang Hua, Wei-dong Shi, Li-hua Tang & Lu-ming Liu
Pages: 1129-1138
Published online: 19 Aug 2013
AbstractforArsenic trioxide inhibits viability of pancreatic cancer stem cells in culture and in a xenograft model via binding to SHH-Gli | Full Text | References | PDF (2.9 MB)
  • 107 Views
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Open Access
Article
Combined upregulation of matrix metalloproteinase-1 and proteinase-activated receptor-1 predicts unfavorable prognosis in human nasopharyngeal carcinoma
Rui Yang, Yu Xu, Peizhong Li, Xin Zhang, Junying Wang, Dongsheng Gu & Yao Wang
Pages: 1139-1146
Published online: 20 Aug 2013
AbstractforCombined upregulation of matrix metalloproteinase-1 and proteinase-activated receptor-1 predicts unfavorable prognosis in human nasopharyngeal carcinoma | Full Text | References | PDF (1.1 MB)
  • 67 Views
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Open Access
Article
Significance of preoperative C-reactive protein as a parameter in patients with small cell carcinoma of the esophagus
Ji-Feng Feng, Hong-Guang Zhao, Jin-Shi Liu & Qi-Xun Chen
Pages: 1147-1151
Published online: 29 Nov 2022
AbstractforSignificance of preoperative C-reactive protein as a parameter in patients with small cell carcinoma of the esophagus | Full Text | References | PDF (483.4 KB)
  • 54 Views
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Open Access
Article
MicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia
Liping Dou, Jingxin Li, Dehua Zheng, Yonghui Li, Xiaoning Gao, Chengwang Xu, Li Gao, Lili Wang & Li Yu
Pages: 1153-1160
Published online: 26 Aug 2013
AbstractforMicroRNA-205 downregulates mixed-lineage-AF4 oncogene expression in acute lymphoblastic leukemia | Full Text | References | PDF (739.7 KB)
  • 66 Views
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Review

Review Article
Clinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer
Jae-il Roh, Young Hoon Sung & Han-Woong Lee
Pages: 1161-1166
Published online: 26 Aug 2013
AbstractforClinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer | Full Text | References | PDF (807.2 KB)
  • 106 Views
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Review Article
Role of microRNAs in hepatocellular carcinoma: a clinical perspective
Elisa Callegari, Bahaeldin K Elamin, Silvia Sabbioni, Laura Gramantieri & Massimo Negrini
Pages: 1167-1178
Published online: 02 Sep 2013
AbstractforRole of microRNAs in hepatocellular carcinoma: a clinical perspective | Full Text | References | PDF (842.6 KB)
  • 143 Views
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Original Research

Article
Clinical outcome of primary small cell carcinoma of the urinary bladder
Chen-Pang Hou, Yu-Hsiang Lin, Chien-Lun Chen, Phei-Lang Chang & Ke-Hung Tsui
Pages: 1179-1185
Published online: 26 Aug 2013
AbstractforClinical outcome of primary small cell carcinoma of the urinary bladder | Full Text | References | PDF (248.3 KB)
  • 62 Views
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Open Access

Case Report

Case Report
Lumbar paravertebral blockade as intractable pain management method in palliative care
Iwona Zaporowska-Stachowiak, Aleksandra Kotlinska-Lemieszek, Grzegorz Kowalski, Katarzyna Kosicka, Karolina Hoffmann, Franciszek Główka & Jacek Łuczak
Pages: 1187-1196
Published online: 03 Sep 2013
AbstractforLumbar paravertebral blockade as intractable pain management method in palliative care | Full Text | References | PDF (1.3 MB)
  • 67 Views
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Open Access

Review

Review Article
Emerging treatment options for recurrent ovarian cancer: the potential role of olaparib
Heather M Shaw & Marcia Hall
Pages: 1197-1206
Published online: 29 Nov 2022
AbstractforEmerging treatment options for recurrent ovarian cancer: the potential role of olaparib | Full Text | References | PDF (1.1 MB)
  • 65 Views
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Review Article
Targeting cancer stem cells: emerging role of Nanog transcription factor
Mong-Lien Wang, Shih-Hwa Chiou & Cheng-Wen Wu
Pages: 1207-1220
Published online: 04 Sep 2013
AbstractforTargeting cancer stem cells: emerging role of Nanog transcription factor | Full Text | References | PDF (300.5 KB)
  • 348 Views
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Review Article
Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence
Sophia N Mowla, Neil D Perkins & Parmjit S Jat
Pages: 1221-1229
Published online: 04 Sep 2013
AbstractforFriend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence | Full Text | References | PDF (603.4 KB)
  • 85 Views
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Review Article
The role of chemotherapy and latest emerging target therapies in anaplastic thyroid cancer
Nerina Denaro, Cristiana Lo Nigro, Elvio G Russi & Marco C Merlano
Pages: 1231-1241
Published online: 16 Sep 2013
AbstractforThe role of chemotherapy and latest emerging target therapies in anaplastic thyroid cancer | Full Text | References | PDF (681.9 KB)
  • 117 Views
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Open Access

Hypothesis

Article
How to detour Treg cells in T cell-based antitumor immune therapy
Shu Zheng, Yanwei Shen, Yongmao Song & Ying Yuan
Pages: 1243-1247
Published online: 29 Nov 2022
AbstractforHow to detour Treg cells in T cell-based antitumor immune therapy | Full Text | References | PDF (169.9 KB)
  • 59 Views
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Review

Review Article
Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition
Ingrid Espinoza, Radhika Pochampally, Fei Xing, Kounosuke Watabe & Lucio Miele
Pages: 1249-1259
Published online: 06 Sep 2013
AbstractforNotch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition | Full Text | References | PDF (1.2 MB)
  • 193 Views
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Review Article
Emerging targets in pancreatic cancer: epithelial–mesenchymal transition and cancer stem cells
Jason A Castellanos, Nipun B Merchant & Nagaraj S Nagathihalli
Pages: 1261-1267
Published online: 13 Sep 2013
AbstractforEmerging targets in pancreatic cancer: epithelial–mesenchymal transition and cancer stem cells | Full Text | References | PDF (1.1 MB)
  • 104 Views
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Original Research

Article
Resveratrol decreases B-cell lymphoma-2 expression and viability in GH3 pituitary adenoma cells of the rat
Benjamin Voellger, Elmar Kirches, Annette Wilisch-Neumann, Andreas Weise, HJ Tapia-Perez, Rosita Rupa, Christian Mawrin & Raimund Firsching
Pages: 1269-1276
Published online: 29 Nov 2022
AbstractforResveratrol decreases B-cell lymphoma-2 expression and viability in GH3 pituitary adenoma cells of the rat | Full Text | References | PDF (423.7 KB)
  • 64 Views
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Open Access
Article
Impact of age on functional exercise correlates in patients with advanced lung cancer
Li-Ying Wang, Huey-Dong Wu, Kuan-Yu Chen, Chen-Hsi Hsieh & Chung-Chun Lai
Pages: 1277-1283
Published online: 16 Sep 2013
AbstractforImpact of age on functional exercise correlates in patients with advanced lung cancer | Full Text | References | PDF (755.3 KB)
  • 65 Views
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Review

Review Article
IAP proteins as targets for drug development in oncology
Laurence Dubrez, Jean Berthelet & Valérie Glorian
Pages: 1285-1304
Published online: 16 Sep 2013
AbstractforIAP proteins as targets for drug development in oncology | Full Text | References | PDF (768.7 KB)
  • 166 Views
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Original Research

Article
Overall survival and disease-free survival in endometrial cancer: prognostic factors in 276 patients
Álvaro Tejerizo-García, Jesús S Jiménez-López, José L Muñoz-González, Sara Bartolomé-Sotillos, Laura Marqueta-Marqués, Gregorio López-González & José F Pérez-Regadera Gómez
Pages: 1305-1313
Published online: 16 Sep 2013
AbstractforOverall survival and disease-free survival in endometrial cancer: prognostic factors in 276 patients | Full Text | References | PDF (619.3 KB)
  • 451 Views
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Open Access
Article
Expression and prognostic relevance of MET and phospho-BAD in non-small cell lung cancer
Wenze Sun, Ting Ai, Ying Gao, Yingbing Zhang, Jie Cui & Liping Song
Pages: 1315-1323
Published online: 18 Sep 2013
AbstractforExpression and prognostic relevance of MET and phospho-BAD in non-small cell lung cancer | Full Text | References | PDF (1.8 MB)
  • 62 Views
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Open Access
Article
Estimation of the displacement of cardiac substructures and the motion of the coronary arteries using electrocardiographic gating
Wenyong Tan, Liying Xu, Xiaohong Wang, Dasheng Qiu, Guang Han & Desheng Hu
Pages: 1325-1332
Published online: 20 Sep 2013
AbstractforEstimation of the displacement of cardiac substructures and the motion of the coronary arteries using electrocardiographic gating | Full Text | References | PDF (737.4 KB)
  • 62 Views
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Open Access
Article
Double siRNA-targeting of cIAP2 and LIVIN results in synergetic sensitization of HCT-116 cells to oxaliplatin treatment
Andrey S Bavykin, Alexandra A Korotaeva, Stanislav V Poyarkov, Alexandr V Syrtsev, Sergei A Tjulandin & Alexandr V Karpukhin
Pages: 1333-1340
Published online: 23 Sep 2013
AbstractforDouble siRNA-targeting of cIAP2 and LIVIN results in synergetic sensitization of HCT-116 cells to oxaliplatin treatment | Full Text | References | PDF (1.9 MB)
  • 73 Views
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Article
The relationship between Lin28 and the chemotherapy response of gastric cancer
Rong Yue Teng, Ji Chun Zhou, Zi Nong Jiang, Chao Yang Xu, Zi Duo Li, Qing Chuan Wang, Chen Pu Xu, Ju Feng Guo, Jian Guo Shen & Lin Bo Wang
Pages: 1341-1345
Published online: 24 Sep 2013
AbstractforThe relationship between Lin28 and the chemotherapy response of gastric cancer | Full Text | References | PDF (872 KB)
  • 59 Views
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Review

Review Article
Emerging targets in cancer management: role of the CXCL12/CXCR4 axis
Monica Cojoc, Claudia Peitzsch, Franziska Trautmann, Leo Polishchuk, Gennady D Telegeev & Anna Dubrovska
Pages: 1347-1361
Published online: 30 Sep 2013
AbstractforEmerging targets in cancer management: role of the CXCL12/CXCR4 axis | Full Text | References | PDF (1.5 MB)
  • 302 Views
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Review Article
Personalized treatment strategies in glioblastoma: MGMT promoter methylation status
Niklas Thon, Simone Kreth & Friedrich-Wilhelm Kreth
Pages: 1363-1372
Published online: 27 Sep 2013
AbstractforPersonalized treatment strategies in glioblastoma: MGMT promoter methylation status | Full Text | References | PDF (246.5 KB)
  • 407 Views
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Original Research

Article
AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines
Pamela Leal, Patricia Garcia, Alejandra Sandoval, Kurt Buchegger, Helga Weber, Oscar Tapia & Juan C Roa
Pages: 1373-1384
Published online: 03 Oct 2013
AbstractforAKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines | Full Text | References | PDF (2 MB)
  • 77 Views
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Open Access
Article
Fludarabine-based versus CHOP-like regimens with or without rituximab in patients with previously untreated indolent lymphoma: a retrospective analysis of safety and efficacy
Xiao-xiao Xu, Bei Yan, Zhen-xing Wang, Yong Yu, Xiao-xiong Wu & Yi-zhuo Zhang
Pages: 1385-1392
Published online: 08 Oct 2013
AbstractforFludarabine-based versus CHOP-like regimens with or without rituximab in patients with previously untreated indolent lymphoma: a retrospective analysis of safety and efficacy | Full Text | References | PDF (265.2 KB)
  • 51 Views
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Case Report

Case Report
Rapid tumor necrosis and massive hemorrhage induced by bevacizumab and paclitaxel combination therapy in a case of advanced breast cancer
Mayu Ono, Tokiko Ito, Toshiharu Kanai, Koichi Murayama, Hiroshi Koyama, Kazuma Maeno, Yasuhiro Mochizuki, Asumi Iesato, Toru Hanamura, Toshihiro Okada, Takayuki Watanabe & Ken-ichi Ito
Pages: 1393-1398
Published online: 07 Oct 2013
AbstractforRapid tumor necrosis and massive hemorrhage induced by bevacizumab and paclitaxel combination therapy in a case of advanced breast cancer | Full Text | References | PDF (1,000.7 KB)
  • 58 Views
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Review

Review Article
The emerging and diverse roles of sirtuins in cancer: a clinical perspective
Hongfeng Yuan, Leila Su & Wen Yong Chen
Pages: 1399-1416
Published online: 08 Oct 2013
AbstractforThe emerging and diverse roles of sirtuins in cancer: a clinical perspective | Full Text | References | PDF (439 KB)
  • 227 Views
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Original Research

Article
Dynamin 3: a new candidate tumor suppressor gene in hepatocellular carcinoma detected by triple combination array analysis
Yoshikuni Inokawa, Shuji Nomoto, Mitsuhiro Hishida, Masamichi Hayashi, Mitsuro Kanda, Yoko Nishikawa, Shin Takeda, Michitaka Fujiwara, Masahiko Koike, Hiroyuki Sugimoto, Tsutomu Fujii, Goro Nakayama, Suguru Yamada, Chie Tanaka, Daisuke Kobayashi & Yasuhiro Kodera
Pages: 1417-1424
Published online: 29 Nov 2022
AbstractforDynamin 3: a new candidate tumor suppressor gene in hepatocellular carcinoma detected by triple combination array analysis | Full Text | References | PDF (902.6 KB)
  • 85 Views
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Review

Review Article
Targeting hedgehog signaling in cancer: research and clinical developments
Jingwu Xie, Christopher M Bartels, Scott W Barton & Dongsheng Gu
Pages: 1425-1435
Published online: 10 Oct 2013
AbstractforTargeting hedgehog signaling in cancer: research and clinical developments | Full Text | References | PDF (605.4 KB)
  • 118 Views
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Original Research

Article
Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer
Zhigang Wang, Zheng Wang, Zhu Liang, Jikuan Liu, Weicheng Shi, Peiru Bai, Xialu Lin, Ruth Magaye & Jinshun Zhao
Pages: 1437-1444
Published online: 16 Oct 2013
AbstractforExpression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer | Full Text | References | PDF (1.6 MB)
  • 138 Views
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Open Access
Article
VEGF is a target molecule for peritoneal metastasis and malignant ascites in gastric cancer: prognostic significance of VEGF in ascites and efficacy of anti-VEGF monoclonal antibody
Sachio Fushida, Katsunobu Oyama, Jun Kinoshita, Yasumichi Yagi, Kouichi Okamoto, Hidehiro Tajima, Itasu Ninomiya, Takashi Fujimura & Tetsuo Ohta
Pages: 1445-1451
Published online: 16 Oct 2013
AbstractforVEGF is a target molecule for peritoneal metastasis and malignant ascites in gastric cancer: prognostic significance of VEGF in ascites and efficacy of anti-VEGF monoclonal antibody | Full Text | References | PDF (1 MB)
  • 102 Views
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Review

Review Article
Survivin – biology and potential as a therapeutic target in oncology
Chun Hei Antonio Cheung, Chien-Chang Huang, Fang-Ying Tsai, Jane Ying-Chieh Lee, Siao Muk Cheng, Yung-Chieh Chang, Yi-Chun Huang, Shang-Hung Chen & Jang-Yang Chang
Pages: 1453-1462
Published online: 16 Oct 2013
AbstractforSurvivin – biology and potential as a therapeutic target in oncology | Full Text | References | PDF (845.3 KB)
  • 204 Views
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Original Research

Article
Transient elastography-based risk estimation of hepatitis B virus-related occurrence of hepatocellular carcinoma: development and validation of a predictive model
Do Young Kim, Ki Jun Song, Seung Up Kim, Eun Jin Yoo, Jun Yong Park, Sang Hoon Ahn & Kwang-Hyub Han
Pages: 1463-1469
Published online: 16 Oct 2013
AbstractforTransient elastography-based risk estimation of hepatitis B virus-related occurrence of hepatocellular carcinoma: development and validation of a predictive model | Full Text | References | PDF (503.7 KB)
  • 65 Views
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Open Access
Article
Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking
Qiang Tan, Guan Wang, Jia Huang, Zhengping Ding, Qingquan Luo, Tony Mok, Qian Tao & Shun Lu
Pages: 1471-1479
Published online: 21 Oct 2013
AbstractforEpigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking | Full Text | References | PDF (340.7 KB)
  • 81 Views
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Open Access
Article
Serum proteomic study on EGFR-TKIs target treatment for patients with NSCLC
Xuan Wu, Wenhua Liang, Xue Hou, Zhong Lin, Hongyun Zhao, Yan Huang, Wenfeng Fang, Yuanyuan Zhao, Jingxun Wu, Yunpeng Yang, Chong Xue, Zhihuang Hu, Jing Zhang, Jianwei Zhang, Yuxiang Ma, Ting Zhou, Tao Qin & Li Zhang
Pages: 1481-1491
Published online: 21 Oct 2013
AbstractforSerum proteomic study on EGFR-TKIs target treatment for patients with NSCLC | Full Text | References | PDF (1.6 MB)
  • 105 Views
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Open Access
Article
The role of second-line chemotherapy in small cell lung cancer: a retrospective analysis
Konstantinos Zarogoulidis, Efimia Boutsikou, Paul Zarogoulidis, Kaid Darwiche, Lutz Freitag, Konstantinos Porpodis, Dimitrios Latsios, Theodoros Kontakiotis, Haidong Huang, Qiang Li, Wolfgang Hohenforst-Schmidt, Maria Kipourou, J Francis Turner & Dionysios Spyratos
Pages: 1493-1500
Published online: 22 Oct 2013
AbstractforThe role of second-line chemotherapy in small cell lung cancer: a retrospective analysis | Full Text | References | PDF (508.3 KB)
  • 64 Views
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Open Access
Article
Ductal adenocarcinoma of the prostate: immunohistochemical findings and clinical significance
Jianjun Sha, Juanjie Bo, Jiahua Pan, Lianhua Zhang, Hanqing Xuan, Wei Chen, Dong Li, Zhaoliang Wang, Dongming Liu & Yiran Huang
Pages: 1501-1506
Published online: 24 Oct 2013
AbstractforDuctal adenocarcinoma of the prostate: immunohistochemical findings and clinical significance | Full Text | References | PDF (2.5 MB)
  • 98 Views
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Article
Retrospective analysis of chronomodulated chemotherapy versus conventional chemotherapy with paclitaxel, carboplatin, and 5-fluorouracil in patients with recurrent and/or metastatic head and neck squamous cell carcinoma
Dan Chen, Jue Cheng, Kai Yang, Yue Ma & Fang Yang
Pages: 1507-1514
Published online: 24 Oct 2013
AbstractforRetrospective analysis of chronomodulated chemotherapy versus conventional chemotherapy with paclitaxel, carboplatin, and 5-fluorouracil in patients with recurrent and/or metastatic head and neck squamous cell carcinoma | Full Text | References | PDF (275.2 KB)
  • 73 Views
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Case Report

Case Report
Endometrial carcinoma with yolk sac tumor-like differentiation and elevated serum β-hCG: a case report and literature review
Mingliang Ji, Yan Lu, Lina Guo, Fengzhi Feng, Xirun Wan & Yang Xiang
Pages: 1515-1522
Published online: 24 Oct 2013
AbstractforEndometrial carcinoma with yolk sac tumor-like differentiation and elevated serum β-hCG: a case report and literature review | Full Text | References | PDF (1.5 MB)
  • 115 Views
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Case Report
Isolated epithelioid trophoblastic tumor of the vagina: a case report and review of the literature
Jing Zhao, Yang Xiang, Dachun Zhao, Tong Ren, Fengzhi Feng & Xirun Wan
Pages: 1523-1526
Published online: 29 Oct 2013
AbstractforIsolated epithelioid trophoblastic tumor of the vagina: a case report and review of the literature | Full Text | References | PDF (891.6 KB)
  • 62 Views
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Original Research

Article
Comparative research on the efficacy of CyberKnife® and surgical excision for Stage I hepatocellular carcinoma
Zhiyong Yuan, Ping Wang, Yongchun Song, Yang Dong & Hongqing Zhuang
Pages: 1527-1532
Published online: 29 Oct 2013
AbstractforComparative research on the efficacy of CyberKnife® and surgical excision for Stage I hepatocellular carcinoma | Full Text | References | PDF (231.1 KB)
  • 90 Views
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Review

Review Article
Focus on treatment of lung carcinoid tumor
Elise Noel-Savina & Renaud Descourt
Pages: 1533-1537
Published online: 25 Oct 2013
AbstractforFocus on treatment of lung carcinoid tumor | Full Text | References | PDF (171.2 KB)
  • 124 Views
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Short Report

Brief Report
Low expression of mixed lineage kinase domain-like protein is associated with poor prognosis in ovarian cancer patients
Ling He, Kuan Peng, Yizhi Liu, Jing Xiong & Fu-fan Zhu
Pages: 1539-1543
Published online: 30 Oct 2013
AbstractforLow expression of mixed lineage kinase domain-like protein is associated with poor prognosis in ovarian cancer patients | Full Text | References | PDF (1.3 MB)
  • 74 Views
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Review

Review Article
New and emerging treatment options for biliary tract cancer
Marcus S Noel & Aram F Hezel
Pages: 1545-1552
Published online: 30 Oct 2013
AbstractforNew and emerging treatment options for biliary tract cancer | Full Text | References | PDF (824.1 KB)
  • 59 Views
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Original Research

Article
Diagnostic efficacy of computed tomography-guided transthoracic needle aspiration and biopsy in patients with pulmonary disease
Tibel Tuna, Sevket Ozkaya, Adem Dirican, Serhat Findik, Atilla G Atici & Levent Erkan
Pages: 1553-1557
Published online: 29 Nov 2022
AbstractforDiagnostic efficacy of computed tomography-guided transthoracic needle aspiration and biopsy in patients with pulmonary disease | Full Text | References | PDF (517.4 KB)
  • 132 Views
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Case Report

Case Report
Successful treatment of paraganglioma with sorafenib: a case report and brief review of the literature
Yun Lin, Qun Li, Wei Huang, Xinyan Jia, Hong Jiang, Yong Gao & Qi Li
Pages: 1559-1562
Published online: 05 Nov 2013
AbstractforSuccessful treatment of paraganglioma with sorafenib: a case report and brief review of the literature | Full Text | References | PDF (1.9 MB)
  • 86 Views
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Original Research

Article
Transcatheter arterial embolization promotes liver tumor metastasis by increasing the population of circulating tumor cells
Zhu-Ting Fang, Guang-Zhi Wang, Wei Zhang, Xu-Dong Qu, Rong Liu, Sheng Qian, Liang Zhu, Bo Zhou & Jian-Hua Wang
Pages: 1563-1572
Published online: 05 Nov 2013
AbstractforTranscatheter arterial embolization promotes liver tumor metastasis by increasing the population of circulating tumor cells | Full Text | References | PDF (2.8 MB)
  • 62 Views
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Review

Review Article
Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers
Chun Wai Mai, Yew Beng Kang & Mallikarjuna Rao Pichika
Pages: 1573-1587
Published online: 05 Nov 2013
AbstractforShould a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers | Full Text | References | PDF (822.5 KB)
  • 291 Views
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Original Research

Article
Nimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial
Jun Liang, Mingyan E, Gang Wu, Lujun Zhao, Xia Li, Xia Xiu, Ning Li, Bo Chen, Zhouguang Hui, Jima Lv, Hui Fang, Yu Tang, Nan Bi, Wenqing Wang, Yirui Zhai, Tao Li, Dongfu Chen, Shuangmei Zou, Ning Lu, Rolando Perez-Rodríguez, Junqi Zheng & Luhua Wang
Pages: 1589-1596
Published online: 06 Nov 2013
AbstractforNimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial | Full Text | References | PDF (1 MB)
  • 96 Views
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Article
Cancer stem cell-related marker expression in lung adenocarcinoma and relevance of histologic subtypes based on IASLC/ATS/ERS classification
Yoshihisa Shimada, Hisashi Saji, Masaharu Nomura, Jun Matsubayashi, Koichi Yoshida, Masatoshi Kakihana, Naohiro Kajiwara, Tatsuo Ohira & Norihiko Ikeda
Pages: 1597-1604
Published online: 08 Nov 2013
AbstractforCancer stem cell-related marker expression in lung adenocarcinoma and relevance of histologic subtypes based on IASLC/ATS/ERS classification | Full Text | References | PDF (3 MB)
  • 71 Views
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Article
Combination of neutrophil lymphocyte ratio and platelet lymphocyte ratio is a useful predictor of postoperative survival in patients with esophageal squamous cell carcinoma
Ji-Feng Feng, Ying Huang & Jin-Shi Liu
Pages: 1605-1612
Published online: 07 Nov 2013
AbstractforCombination of neutrophil lymphocyte ratio and platelet lymphocyte ratio is a useful predictor of postoperative survival in patients with esophageal squamous cell carcinoma | Full Text | References | PDF (697.4 KB)
  • 84 Views
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Review

Review Article
Profile of panobinostat and its potential for treatment in solid tumors: an update
Madhurima Anne, Daniel Sammartino, Myra F Barginear & Daniel Budman
Pages: 1613-1624
Published online: 15 Nov 2013
AbstractforProfile of panobinostat and its potential for treatment in solid tumors: an update | Full Text | References | PDF (355 KB)
  • 139 Views
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Original Research

Article
Increased expression of microRNA-335 predicts a favorable prognosis in primary gallbladder carcinoma
Hong-hua Peng, Yang-de Zhang, Lian-sheng Gong, Wei-dong Liu & Yang Zhang
Pages: 1625-1630
Published online: 11 Nov 2013
AbstractforIncreased expression of microRNA-335 predicts a favorable prognosis in primary gallbladder carcinoma | Full Text | References | PDF (232.9 KB)
  • 74 Views
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Case Report

Case Report
Pulmonary adenocarcinoma with osseous metaplasia: a rare occurrence possibly associated with early stage?
Qingfu Zhang, Liying Yin, Bo Li, Rui Meng, Runa Dao, Suxiang Hu & Xueshan Qiu
Pages: 1631-1634
Published online: 29 Nov 2022
AbstractforPulmonary adenocarcinoma with osseous metaplasia: a rare occurrence possibly associated with early stage? | Full Text | References | PDF (933.9 KB)
  • 81 Views
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Original Research

Article
Development of an immunotherapeutic adenovirus targeting hormone-independent prostate cancer
Jae Sik Kim, Sang Don Lee, Sang Jin Lee & Moon Kee Chung
Pages: 1635-1642
Published online: 29 Nov 2022
AbstractforDevelopment of an immunotherapeutic adenovirus targeting hormone-independent prostate cancer | Full Text | References | PDF (1.1 MB)
  • 51 Views
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Article
The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells
Feng Chai, Jiangang Zhou, Cheng Chen, Song Xie, Xiao Chen, Ping Su & Jun Shi
Pages: 1643-1647
Published online: 12 Nov 2013
AbstractforThe Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells | Full Text | References | PDF (208.7 KB)
  • 79 Views
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Article
Synchronous BRAFV600E and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity
Jules Gadiot, Anna I Hooijkaas, Marcel A Deken & Christian U Blank
Pages: 1649-1658
Published online: 28 Nov 2013
AbstractforSynchronous BRAFV600E and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity | Full Text | References | PDF (2.1 MB)
  • 74 Views
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Article
Prognostic factors associated with solitary plasmacytoma
Shan-qi Guo, Le Zhang, Ya-fei Wang, Bao-cun Sun, Lian-yu Zhang, Jin Zhang, Guowen Wang & Yi-zhuo Zhang
Pages: 1659-1666
Published online: 14 Nov 2013
AbstractforPrognostic factors associated with solitary plasmacytoma | Full Text | References | PDF (301.4 KB)
  • 111 Views
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Article
B7-H3 is a new cancer-specific endothelial marker in clear cell renal cell carcinoma
Xiaojian Qin, Hailiang Zhang, Dingwei Ye, Bo Dai, Yao Zhu & Guohai Shi
Pages: 1667-1673
Published online: 15 Nov 2013
AbstractforB7-H3 is a new cancer-specific endothelial marker in clear cell renal cell carcinoma | Full Text | References | PDF (1.4 MB)
  • 85 Views
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Review

Review Article
Exploring and exploiting the fundamental role of microRNAs in tumor pathogenesis
Qingbao Cheng & Xiaoqing Jiang
Pages: 1675-1684
Published online: 29 Nov 2022
AbstractforExploring and exploiting the fundamental role of microRNAs in tumor pathogenesis | Full Text | References | PDF (202.5 KB)
  • 75 Views
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Original Research

Article
Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway
Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi & Takanobu Yoshida
Pages: 1685-1693
Published online: 18 Nov 2013
AbstractforNiclosamide suppresses Hepatoma cell proliferation via the Wnt pathway | Full Text | References | PDF (1.4 MB)
  • 77 Views
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Article
Intraoperative radiotherapy in stage IIB adenocarcinoma of the uterine cervix: a retrospective study
Ying Gao, Zi Liu, Fei Gao & Xi Chen
Pages: 1695-1700
Published online: 20 Nov 2013
AbstractforIntraoperative radiotherapy in stage IIB adenocarcinoma of the uterine cervix: a retrospective study | Full Text | References | PDF (228.1 KB)
  • 51 Views
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Article
Body mass index and patient CT measurements as a predictor of benefit of intensity-modulated radiotherapy to the supraclavicular fossa
Vicky Koh, Johann I Tang, Bok Ai Choo, Chek Wee Tan, Boon Keat Lim, Liang Shen & Jiade Jay Lu
Pages: 1701-1706
Published online: 21 Nov 2013
AbstractforBody mass index and patient CT measurements as a predictor of benefit of intensity-modulated radiotherapy to the supraclavicular fossa | Full Text | References | PDF (514.7 KB)
  • 54 Views
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Article
Gemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancer cells by inhibiting DNA synthesis and increasing cell apoptosis
Guixiu Jin, Jing Zhao, Hongyan Qi, Meng Lou, Xia Liu, Yu Qu, Lingjun Zhao, Weifeng Zhang, Jimin Shao & Huizhen Zhong
Pages: 1707-1717
Published online: 25 Nov 2013
AbstractforGemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancer cells by inhibiting DNA synthesis and increasing cell apoptosis | Full Text | References | PDF (2.2 MB)
  • 133 Views
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Article
Target volume and position variations during intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma
Wenyong Tan, Yanping Li, Guang Han, Jiaozhen Xu, Xiaohong Wang, Ying Li & Desheng Hu
Pages: 1719-1728
Published online: 21 Nov 2013
AbstractforTarget volume and position variations during intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma | Full Text | References | PDF (1.3 MB)
  • 67 Views
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Review

Review Article
The potential for targeting extracellular LOX proteins in human malignancy
Alejandro Mayorca-Guiliani & Janine T Erler
Pages: 1729-1735
Published online: 25 Nov 2013
AbstractforThe potential for targeting extracellular LOX proteins in human malignancy | Full Text | References | PDF (1.2 MB)
  • 83 Views
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Original Research

Article
Signal transduction molecule patterns indicating potential glioblastoma therapy approaches
Maria Linda Cruceru, Ana-Maria Enciu, Adrian Claudiu Popa, Radu Albulescu, Monica Neagu, Cristiana Pistol Tanase & Stefan N Constantinescu
Pages: 1737-1749
Published online: 29 Nov 2013
AbstractforSignal transduction molecule patterns indicating potential glioblastoma therapy approaches | Full Text | References | PDF (1.8 MB)
  • 73 Views
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Article
Sam68 is a novel marker for aggressive neuroblastoma
Xiaohong Zhao, Zuoqing Li, Benfu He, Juncheng Liu, Suisheng Li, Li Zhou, Cuiling Pan, Zhe Yu & Zhe Xu
Pages: 1751-1760
Published online: 02 Dec 2013
AbstractforSam68 is a novel marker for aggressive neuroblastoma | Full Text | References | PDF (1.3 MB)
  • 77 Views
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Article
Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation
Luigi Rossi, Enzo Veltri, Angelo Zullo, Federica Zoratto, Maria Colonna, Flavia Longo, Marcella Mottolese, Diana Giannarelli, Luigi Ruco, Paolo Marchetti, Adriana Romiti, Viola Barucca, Giuseppe Giannini, Loredana Bianchi & Silverio Tomao
Pages: 1761-1769
Published online: 29 Nov 2013
AbstractforMetastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation | Full Text | References | PDF (673.6 KB)
  • 66 Views
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Article
Sequential treatment of tyrosine kinase inhibitors and chemotherapy for EGFR-mutated non-small cell lung cancer: a meta-analysis of Phase III trials
Yiliang Zhang, Yihua Sun, Lei Wang, Ting Ye, Yunjian Pan, Haichuan Hu, Yongfu Yu, Naiqing Zhao, Yanyan Song, David Garfield & Haiquan Chen
Pages: 1771-1777
Published online: 29 Nov 2013
AbstractforSequential treatment of tyrosine kinase inhibitors and chemotherapy for EGFR-mutated non-small cell lung cancer: a meta-analysis of Phase III trials | Full Text | References | PDF (278.7 KB)
  • 59 Views
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Article
Optical imaging of head and neck squamous cell carcinoma in vivo using arginine-glycine-aspartic acid peptide conjugated near-infrared quantum dots
Hao Huang, Yun-Long Bai, Kai Yang, Hong Tang & You-Wei Wang
Pages: 1779-1787
Published online: 02 Dec 2013
AbstractforOptical imaging of head and neck squamous cell carcinoma in vivo using arginine-glycine-aspartic acid peptide conjugated near-infrared quantum dots | Full Text | References | PDF (2.9 MB)
  • 85 Views
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Article
Chemotherapy and EGFR tyrosine kinase inhibitors for treatment of brain metastases from non-small-cell lung cancer: survival analysis in 210 patients
Yun Fan, Zhiyu Huang, Luo Fang, Lulu Miu, Nengming Lin, Lei Gong, Haifeng Yu, Haiyan Yang & Weimin Mao
Pages: 1789-1803
Published online: 29 Nov 2022
AbstractforChemotherapy and EGFR tyrosine kinase inhibitors for treatment of brain metastases from non-small-cell lung cancer: survival analysis in 210 patients | Full Text | References | PDF (457.1 KB)
  • 94 Views
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Article
A functional polymorphism in the epidermal growth factor gene predicts hepatocellular carcinoma risk in Japanese hepatitis C patients
Masaya Suenaga, Suguru Yamada, Tsutomu Fujii, Bryan C Fuchs, Norio Okumura, Mitsuro Kanda, Daisuke Kobayashi, Chie Tanaka, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Shin Takeda, Kazuhiko Hayashi, Kenneth K Tanabe, Hidemi Goto & Yasuhiro Kodera
Pages: 1805-1812
Published online: 13 Dec 2013
AbstractforA functional polymorphism in the epidermal growth factor gene predicts hepatocellular carcinoma risk in Japanese hepatitis C patients | Full Text | References | PDF (619.3 KB)
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