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Original Research

Influence of CYP2D6, CYP3A5, ABCB1, APOE polymorphisms and nongenetic factors on donepezil treatment in patients with Alzheimer’s disease and vascular dementia

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Pages 209-224 | Published online: 04 Sep 2019

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Monpat Chamnanphon, Sorawit Wainipitapong, Teeravut Wiwattarangkul, Phenphichcha Chuchuen, Kunathip Nissaipan, Weeraya Phaisal, Sookjaroen Tangwongchai, Chonlaphat Sukasem, Supeecha Wittayalertpanya, Andrea Gaedigk, Daruj Aniwattanapong & Pajaree Chariyavilaskul. (2020) CYP2D6 Predicts Plasma Donepezil Concentrations in a Cohort of Thai Patients with Mild to Moderate Dementia. Pharmacogenomics and Personalized Medicine 13, pages 543-551.
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Ramon Cacabelos. (2020) Pharmacogenomics of drugs used to treat brain disorders. Expert Review of Precision Medicine and Drug Development 5:3, pages 181-234.
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Articles from other publishers (7)

Federico Emanuele Pozzi, Elisa Conti, Ildebrando Appollonio, Carlo Ferrarese & Lucio Tremolizzo. (2022) Predictors of response to acetylcholinesterase inhibitors in dementia: A systematic review. Frontiers in Neuroscience 16.
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Sara Ben Halla, Amal Tazzite, Bouchaïb Gazzaz, Hind Dehbi & Bouchra El Moutawakil. (2022) The impact of ABCB1 gene polymorphism (C3435T) and its expression on response to Donepezil in Moroccan patients with Alzheimer's disease. Gene Reports 26, pages 101443.
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Yoshiyuki Kagawa, Yoshiaki Yamamoto, Ayami Ueno, Kengo Inomata, Mayu Tezuka, Takashi Osawa, Yasuharu Yazawa, Toshio Maeda & Tomokazu Obi. (2021) Impact of Plasma Donepezil Concentration on Behavioral and Psychological Symptoms of Dementia in Patients with Alzheimer’s Disease. Dementia and Geriatric Cognitive Disorders Extra 11:3, pages 264-272.
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Firoz Akhter, Alicia Persaud, Younis Zaokari, Zhen Zhao & Donghui Zhu. (2021) Vascular Dementia and Underlying Sex Differences. Frontiers in Aging Neuroscience 13.
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Jin Lu, Xiuzhe Wang, Lili Wan, Jianliang Fu, Yan Huo, Yuwu Zhao & Cheng Guo. (2020) Gene Polymorphisms Affecting the Pharmacokinetics and Pharmacodynamics of Donepezil Efficacy. Frontiers in Pharmacology 11.
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Derek Spieler, Christian Namendorf, Tamara Namendorf, Maja von Cube & Manfred Uhr. (2020) Donepezil, a cholinesterase inhibitor used in Alzheimer's disease therapy, is actively exported out of the brain by abcb1ab p-glycoproteins in mice. Journal of Psychiatric Research 124, pages 29-33.
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Ramon Cacabelos. (2020) Pharmacogenomics of Cognitive Dysfunction and Neuropsychiatric Disorders in Dementia. International Journal of Molecular Sciences 21:9, pages 3059.
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