Pharmacogenomics and Personalized Medicine, Volume 12, Issue (2019)

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Pharmacogenomics and Personalized Medicine, Volume 12, Issue (2019)

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Original Research

Article
Effects of coagulation factor VII polymorphisms on warfarin sensitivity and responsiveness in Jordanian cardiovascular patients during the initiation and maintenance phases of warfarin therapy
Laith N AL-Eitan, Ayah Y Almasri & Sahar O Al-Habahbeh
Pages: 1-8
Published online: 22 Dec 2022
AbstractforEffects of coagulation factor VII polymorphisms on warfarin sensitivity and responsiveness in Jordanian cardiovascular patients during the initiation and maintenance phases of warfarin therapy | Full Text | References | PDF (166.9 KB) | EPUB
  • 115 Views
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Open Access
Article
Precision medicine approaches for the management of Ewing sarcoma: current perspectives
Victoria T Rizk, Christine M Walko & Andrew S Brohl
Pages: 9-14
Published online: 22 Dec 2022
AbstractforPrecision medicine approaches for the management of Ewing sarcoma: current perspectives | Full Text | References | PDF (150.6 KB) | EPUB
  • 114 Views
  • 5 CrossRef citations
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Open Access
Article
Impact of a variable number tandem repeat in the CYP2C9 promoter on warfarin sensitivity and responsiveness in Jordanians with cardiovascular disease
Laith N AL-Eitan, Ayah Y Almasri & Sahar O Al-Habahbeh
Pages: 15-22
Published online: 22 Dec 2022
AbstractforImpact of a variable number tandem repeat in the CYP2C9 promoter on warfarin sensitivity and responsiveness in Jordanians with cardiovascular disease | Full Text | References | PDF (171.2 KB) | EPUB
  • 137 Views
  • 6 CrossRef citations
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Open Access
Article
Population’s perspectives toward biobanks in scientific research: a study from Jordan
Hanin Makhlouf, Nasr Alrabadi, Omar F Khabour, Karem H Alzoubi & Wael Al-Delaimy
Pages: 23-32
Published online: 22 Dec 2022
AbstractforPopulation’s perspectives toward biobanks in scientific research: a study from Jordan | Full Text | References | PDF (532.1 KB) | EPUB
  • 121 Views
  • 13 CrossRef citations
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Open Access
Article
Identification of genetic variants associated with skeletal muscle function deficit in childhood acute lymphoblastic leukemia survivors
Geneviève Nadeau, Erika Ouimet-Grennan, Michelle Aaron, Simon Drouin, Laurence Bertout, Albert Shalmiev, Patrick Beaulieu, Pascal St-Onge, Louis-Nicolas Veilleux, Frank Rauch, Kateryna Petrykey, Caroline Laverdière, Daniel Sinnett, Nathalie Alos & Maja Krajinovic
Pages: 33-45
Published online: 22 Dec 2022
AbstractforIdentification of genetic variants associated with skeletal muscle function deficit in childhood acute lymphoblastic leukemia survivors | Full Text | References | PDF (421.4 KB) | EPUB
  • 104 Views
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Open Access
Article
VKORC1 variants as significant predictors of warfarin dose in Emiratis
Zeina N Al-Mahayri, Hayat S Al Jaibeji, Yolande Saab, Karem Soliman, Lihadh Al-Gazali, George P Patrinos & Bassam R Ali
Pages: 47-57
Published online: 22 Dec 2022
AbstractforVKORC1 variants as significant predictors of warfarin dose in Emiratis | Full Text | References | PDF (357.4 KB) | EPUB
  • 201 Views
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Open Access

Review

Review Article
Personalized medicine in breast cancer: pharmacogenomics approaches
Shabnam Jeibouei, Mohammad Esmael Akbari, Alireza Kalbasi, Amir Reza Aref, Mohammad Ajoudanian, Alireza Rezvani & Hakimeh Zali
Pages: 59-73
Published online: 22 Dec 2022
AbstractforPersonalized medicine in breast cancer: pharmacogenomics approaches | Full Text | References | PDF (896.8 KB) | EPUB
  • 1213 Views
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Open Access

Methodology

Article
g-Nomic: a new pharmacogenetics interpretation software
Ana Sabater, Carlos J Ciudad, Marc Cendros, Denis Dobrokhotov & Juan Sabater-Tobella
Pages: 75-85
Published online: 22 Dec 2022
Abstractforg-Nomic: a new pharmacogenetics interpretation software | Full Text | References | PDF (3 MB) | EPUB
  • 135 Views
  • 5 CrossRef citations
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Open Access

Original Research

Article
Effects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients
Laith N AL-Eitan, Islam M Al-Dalalah, Mohamed M Mustafa, Mansour A Alghamdi, Afrah K Elshammari, Wael H Khreisat & Hanan A Aljamal
Pages: 87-95
Published online: 10 Jun 2019
AbstractforEffects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients | Full Text | References | PDF (263 KB) | EPUB
  • 157 Views
  • 12 CrossRef citations
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Open Access
Article
Plasma brain-derived neurotrophic factor (BDNF) concentration and the BDNF Val66Met polymorphism in suicide: a prospective study in patients with depressive disorder
Ming Ai, Jun Wang, Jianmei Chen, Wo Wang, Xiaoming Xu, Yao Gan, Xuemei Li, Xinyuan Gou, Jun Cao, Zhen Lv, Xiaorong Chen, Hengguang Wang, Qing Ma & Li Kuang
Pages: 97-106
Published online: 02 Jul 2019
AbstractforPlasma brain-derived neurotrophic factor (BDNF) concentration and the BDNF Val66Met polymorphism in suicide: a prospective study in patients with depressive disorder | Full Text | References | PDF (310.3 KB) | EPUB
  • 198 Views
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Open Access

Review

Article
Inconsistency in race and ethnic classification in pharmacogenetics studies and its potential clinical implications
Frederick Zhang & Joseph Finkelstein
Pages: 107-123
Published online: 02 Jul 2019
AbstractforInconsistency in race and ethnic classification in pharmacogenetics studies and its potential clinical implications | Full Text | References | PDF (525.5 KB) | EPUB
  • 357 Views
  • 28 CrossRef citations
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Open Access
Review Article
Update on the pharmacogenomics of pain management
Alan David Kaye, Andrew Jesse Garcia, O Morgan Hall, George M Jeha, Kelsey D Cramer, Amanda L Granier, Anusha Kallurkar, Elyse M Cornett & Richard D Urman
Pages: 125-143
Published online: 03 Jul 2019
AbstractforUpdate on the pharmacogenomics of pain management | Full Text | References | PDF (1.1 MB) | EPUB
  • 644 Views
  • 19 CrossRef citations
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Open Access
Case Report
Potential role of pharmacogenomics testing in the setting of enhanced recovery pathways after surgery
Hamdy Awad, Ahmed Ahmed, Richard D Urman, Nicoleta Stoicea & Sergio D Bergese
Pages: 145-154
Published online: 26 Jul 2019
AbstractforPotential role of pharmacogenomics testing in the setting of enhanced recovery pathways after surgery | Full Text | References | PDF (339.1 KB) | EPUB
  • 165 Views
  • 3 CrossRef citations
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Open Access

Original Research

Article
Association between polymorphisms of LEP, LEPR, DRD2, HTR2A and HTR2C genes and risperidone- or clozapine-induced hyperglycemia
Apichaya Puangpetch, Pornpen Srisawasdi, Weerapon Unaharassamee, Napa Jiratjintana, Somlak Vanavanan, Suweejuk Punprasit, Chalitpon Na Nakorn, Chonlaphat Sukasem & Martin H Kroll
Pages: 155-166
Published online: 06 Aug 2019
AbstractforAssociation between polymorphisms of LEP, LEPR, DRD2, HTR2A and HTR2C genes and risperidone- or clozapine-induced hyperglycemia | Full Text | References | PDF (461.4 KB) | EPUB
  • 166 Views
  • 5 CrossRef citations
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Open Access

Review

Article
A personalized approach to acute myeloid leukemia therapy: current options
Raveen Stephen Stallon Illangeswaran, Saswati Das, Daniel Zechariah Paul, Vikram Mathews & Poonkuzhali Balasubramanian
Pages: 167-179
Published online: 22 Dec 2022
Abstractfor A personalized approach to acute myeloid leukemia therapy: current options | Full Text | References | PDF (913.9 KB) | EPUB
  • 190 Views
  • 2 CrossRef citations
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Open Access

Original Research

Article
Toxicogenomic analysis of publicly available transcriptomic data can predict food, drugs, and chemical-induced asthma
Mahmood Yaseen Hachim, Ibrahim Yaseen Hachim, Noha M Elemam & Rifat A Hamoudi
Pages: 181-199
Published online: 26 Aug 2019
AbstractforToxicogenomic analysis of publicly available transcriptomic data can predict food, drugs, and chemical-induced asthma | Full Text | References | PDF (3.6 MB) | EPUB
  • 136 Views
  • 4 CrossRef citations
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Open Access
Article
The influence of an IL-4 variable number tandem repeat (VNTR) polymorphism on breast cancer susceptibility
Laith N AL-Eitan, Doaa M Rababa’h, Mansour A Alghamdi & Rame H Khasawneh
Pages: 201-207
Published online: 26 Aug 2019
AbstractforThe influence of an IL-4 variable number tandem repeat (VNTR) polymorphism on breast cancer susceptibility | Full Text | References | PDF (570.4 KB) | EPUB
  • 140 Views
  • 4 CrossRef citations
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Open Access
Article
Influence of CYP2D6, CYP3A5, ABCB1, APOE polymorphisms and nongenetic factors on donepezil treatment in patients with Alzheimer’s disease and vascular dementia
Thitipon Yaowaluk, Vorapun Senanarong, Chanin Limwongse, Rasda Boonprasert & Pornpimol Kijsanayotin
Pages: 209-224
Published online: 22 Dec 2022
AbstractforInfluence of CYP2D6, CYP3A5, ABCB1, APOE polymorphisms and nongenetic factors on donepezil treatment in patients with Alzheimer’s disease and vascular dementia | Full Text | References | PDF (642.5 KB) | EPUB
  • 222 Views
  • 9 CrossRef citations
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Open Access
Article
Genetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case–control study
Laith N AL-Eitan, Islam M Al-Dalalah, Mohamed M Mustafa, Mansour A Alghamdi, Afrah K Elshammari, Wael H Khreisat, Mohammed N Al-Quasmi & Hanan A Aljamal
Pages: 225-233
Published online: 22 Dec 2022
AbstractforGenetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case–control study | Full Text | References | PDF (1.8 MB) | EPUB
  • 138 Views
  • 3 CrossRef citations
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Open Access

Review

Review Article
Personalized treatment options for thyroid cancer: current perspectives
Fatemeh Khatami, Bagher Larijani, Shekoufeh Nikfar, Mandana Hasanzad, Kiarad Fendereski & Seyed Mohammad Tavangar
Pages: 235-245
Published online: 13 Sep 2019
AbstractforPersonalized treatment options for thyroid cancer: current perspectives | Full Text | References | PDF (692.9 KB) | EPUB
  • 350 Views
  • 8 CrossRef citations
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Open Access

Original Research

Article
Knowledge And Attitudes Of Pharmacy Students Towards Pharmacogenomics Among Universities In Jordan And West Bank Of Palestine
Yazun Jarrar, Rami Mosleh, Mohammed Hawash & Qais Jarrar
Pages: 247-255
Published online: 07 Oct 2019
AbstractforKnowledge And Attitudes Of Pharmacy Students Towards Pharmacogenomics Among Universities In Jordan And West Bank Of Palestine | Full Text | References | PDF (366.1 KB) | EPUB
  • 226 Views
  • 12 CrossRef citations
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Open Access

Review

Article
Diversity In Precision Medicine And Pharmacogenetics: Methodological And Conceptual Considerations For Broadening Participation
Alice B Popejoy
Pages: 257-271
Published online: 22 Dec 2022
AbstractforDiversity In Precision Medicine And Pharmacogenetics: Methodological And Conceptual Considerations For Broadening Participation | Full Text | References | PDF (3.1 MB) | EPUB
  • 335 Views
  • 9 CrossRef citations
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Open Access
Article
Pharmacogenomic Testing In Pediatrics: Navigating The Ethical, Social, And Legal Challenges
Susanne B Haga
Pages: 273-285
Published online: 22 Dec 2022
AbstractforPharmacogenomic Testing In Pediatrics: Navigating The Ethical, Social, And Legal Challenges | Full Text | References | PDF (460.1 KB) | EPUB
  • 336 Views
  • 3 CrossRef citations
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Open Access

Original Research

Article
The AKR1D1*36 (rs1872930) Allelic Variant Is Independently Associated With Clopidogrel Treatment Outcome
Aleksandra Kapedanovska-Nestorovska, Aleksandar J Dimovski, Zoran Sterjev, Nadica Matevska Geskovska, Ljubica Suturkova, Petar Ugurov, Zan Mitrev & Rodney Rosalia
Pages: 287-295
Published online: 21 Oct 2019
AbstractforThe AKR1D1*36 (rs1872930) Allelic Variant Is Independently Associated With Clopidogrel Treatment Outcome | Full Text | References | PDF (2.4 MB) | EPUB
  • 96 Views
  • 3 CrossRef citations
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Open Access
Article
Genotypic Resistance Remains A Concern In Chronic Hepatitis B Patients With High Viral Load After Lamivudine And Adefovir Combination Therapy
Meijin Huang, Jie Zhong, Chunlei Lu, Fenglian Deng, Li Li, Yixi Nong, Liudan Liang, Houji Qin & Yibin Deng
Pages: 297-303
Published online: 21 Oct 2019
AbstractforGenotypic Resistance Remains A Concern In Chronic Hepatitis B Patients With High Viral Load After Lamivudine And Adefovir Combination Therapy | Full Text | References | PDF (1.9 MB) | EPUB
  • 85 Views
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Open Access

Review

Review Article
Concepts Driving Pharmacogenomics Implementation Into Everyday Healthcare
Jyothsna Giri, Ann M Moyer, Suzette J Bielinski & Pedro J Caraballo
Pages: 305-318
Published online: 30 Oct 2019
AbstractforConcepts Driving Pharmacogenomics Implementation Into Everyday Healthcare | Full Text | References | PDF (2.7 MB) | EPUB
  • 251 Views
  • 8 CrossRef citations
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Open Access

Original Research

Article
A Novel Mutation Of The EMD Gene In A Family With Cardiac Conduction Abnormalities And A High Incidence Of Sudden Cardiac Death
Demiao Kong, Yi Zhan, Canzhao Liu, Yerong Hu, Yangzhao Zhou, Jiawen Luo, Lu Gu, Xinmin Zhou & Zhiwei Zhang
Pages: 319-327
Published online: 31 Oct 2019
AbstractforA Novel Mutation Of The EMD Gene In A Family With Cardiac Conduction Abnormalities And A High Incidence Of Sudden Cardiac Death | Full Text | References | PDF (3.7 MB) | EPUB
  • 114 Views
  • 3 CrossRef citations
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Open Access
Article
Antihypertensive Effect Of Amlodipine In Co-Administration With Omeprazole In Patients With Hypertension And Acid-Related Disorders: Cytochrome P450-Associated Aspects
Margarita N Dorofeeva, Evgenia V Shikh, Zhanna M Sizova, Alisa V Tarasenko, Natalia P Denisenko, Valeriy V Smirnov, Kristina A Ryzhikova, Zhannet A Sozaeva, Elena A Grishina & Dmitriy A Sychev
Pages: 329-339
Published online: 22 Dec 2022
AbstractforAntihypertensive Effect Of Amlodipine In Co-Administration With Omeprazole In Patients With Hypertension And Acid-Related Disorders: Cytochrome P450-Associated Aspects | Full Text | References | PDF (511.9 KB) | EPUB
  • 1702 Views
  • 2 CrossRef citations
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Open Access

Review

Review Article
Pharmacogenomics And Hypertension: Current Insights
Gustavo H Oliveira-Paula, Sherliane C Pereira, Jose E Tanus-Santos & Riccardo Lacchini
Pages: 341-359
Published online: 22 Nov 2019
AbstractforPharmacogenomics And Hypertension: Current Insights | Full Text | References | PDF (557.4 KB) | EPUB
  • 811 Views
  • 13 CrossRef citations
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Open Access
Review Article
OPRM1 A118G Polymorphisms and Its Role in Opioid Addiction: Implication on Severity and Treatment Approaches
Malik Mumtaz Taqi, Muhammad Faisal & Hadar Zaman
Pages: 361-368
Published online: 27 Nov 2019
AbstractforOPRM1 A118G Polymorphisms and Its Role in Opioid Addiction: Implication on Severity and Treatment Approaches | Full Text | References | PDF (398.9 KB) | EPUB
  • 607 Views
  • 15 CrossRef citations
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Open Access

Original Research

Article
Individualized Drug Repositioning For Rheumatoid Arthritis Using Weighted Kolmogorov–Smirnov Algorithm
Ru-Yin Hu, Xiao-Bin Tian, Bo Li, Rui Luo, Bin Zhang & Jin-Min Zhao
Pages: 369-375
Published online: 11 Dec 2019
AbstractforIndividualized Drug Repositioning For Rheumatoid Arthritis Using Weighted Kolmogorov–Smirnov Algorithm | Full Text | References | PDF (268.7 KB) | EPUB
  • 116 Views
  • 2 CrossRef citations
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Open Access
Article
Evaluation of Hematological Parameters in the Genetic Prospective in Epileptic Patients of Khyber Pakhtunkhwa
Nazish Farooq, Niaz Ali & Shakir Ullah
Pages: 377-385
Published online: 22 Dec 2022
AbstractforEvaluation of Hematological Parameters in the Genetic Prospective in Epileptic Patients of Khyber Pakhtunkhwa | Full Text | References | PDF (1.2 MB) | EPUB
  • 131 Views
  • 0 CrossRef citations
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Open Access
Article
Identification of Candidate Genes and Therapeutic Agents for Light Chain Amyloidosis Based on Bioinformatics Approach
Wenxiang Bai, Honghua Wang & Hua Bai
Pages: 387-396
Published online: 03 Jan 2020
AbstractforIdentification of Candidate Genes and Therapeutic Agents for Light Chain Amyloidosis Based on Bioinformatics Approach | Full Text | References | PDF (2 MB) | EPUB
  • 158 Views
  • 2 CrossRef citations
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Open Access
Article
CYP2C19*2 Polymorphism Is Associated with Impaired Oral Clearance of Gliclazide in Healthy Chinese
Elaine Chow, Emily WM Poon, Benny SP Fok, Juliana CN Chan & Brian Tomlinson
Pages: 397-401
Published online: 22 Dec 2022
AbstractforCYP2C19*2 Polymorphism Is Associated with Impaired Oral Clearance of Gliclazide in Healthy Chinese | Full Text | References | PDF (574.7 KB) | EPUB
  • 108 Views
  • 4 CrossRef citations
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Open Access

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