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Review

Osteoporosis and type 2 diabetes mellitus: what do we know, and what we can do?

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Pages 435-448 | Published online: 11 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Dan Liu, Jing-Jie Bai, Jun-Jie Yao, Yong-Bo Wang, Tong Chen, Qian Xing & Ran Bai. (2021) Association of Insulin Glargine Treatment with Bone Mineral Density in Patients with Type 2 Diabetes Mellitus. Diabetes, Metabolic Syndrome and Obesity 14, pages 1909-1917.
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Ying Tang, Lilin Gong, Xiangjun Chen, Zhipeng Du, Jinbo Hu, Zhixin Xu, Jinshan Wu, Qifu Li & Zhihong Wang. (2020) Age-Related Changes in Body Composition and Bone Mineral Density and Their Relationship with the Duration of Diabetes and Glycaemic Control in Type 2 Diabetes. Diabetes, Metabolic Syndrome and Obesity 13, pages 4699-4710.
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Minyan Liu, Yanhui Lu, Xiaoling Cheng, Lichao Ma, Xinyu Miao, Nan Li, Boruo Sun, Shuangtong Yan, Jian Li & Chunling Li. (2019) Relationship between abnormal glucose metabolism and osteoporosis in Han Chinese men over the age of 50 years. Clinical Interventions in Aging 14, pages 445-451.
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Articles from other publishers (52)

Na Xu, Yan Wang, Yu Chen, Yu-ning Guo, Ren-xuan Li, Yan-man Zhou & Jin Xu. (2023) The associations between uric acid with BMDs and risk of the 10-year probability of fractures in Chinese patients with T2DM stratified by age and gender. Endocrine 80:3, pages 520-528.
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Nataliia Grygorieva, Anna Musiienko, Nataliia Zaverukha, Maryna Bystrytska & Roksolana Povoroznyuk. (2022) BONE MINERAL DENSITY AND PROBABILITY OF OSTEOPOROTIC FRACTURES IN WOMEN WITH TYPE II DIABETES MELLITUS. Wiadomości Lekarskie 75:12, pages 2920-2925.
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Maorui Zhang, Yujin Gao, Qing Li, Huayue Cao, Jianghua Yang, Xiaoxiao Cai & Jingang Xiao. (2022) Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin signaling pathway. Stem Cell Research & Therapy 13:1.
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Pei Zhang, Xiaofeng Huang, Yanping Gong, Yanhui Lu, Minyan Liu, Xiaoling Cheng, Nan Li & Chunlin Li. (2022) The study of bone mineral density measured by quantitative computed tomography in middle-aged and elderly men with abnormal glucose metabolism. BMC Endocrine Disorders 22:1.
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Xiaorong Hu, He Gong, Aiqi Hou, Xiaodan Wu, Peipei Shi & Yingying Zhang. (2022) Effects of continuous subcutaneous insulin infusion on the microstructures, mechanical properties and bone mineral compositions of lumbar spines in type 2 diabetic rats. BMC Musculoskeletal Disorders 23:1.
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Miao Zhang, Yuexuan Li, Lifei Liu, Mei Huang, Miao Wang & Jun Zou. (2022) The effects on type 2 diabetes mellitus mouse femoral bone achieved by anti-osteoporosis exercise interventions. Frontiers in Endocrinology 13.
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Shaymaa Abdalwahed Abdulameer, Mohanad Naji Sahib & Syed Azhar Syed Sulaiman. (2022) Cognitive perspective of osteoporosis among adults with type 2 diabetes mellitus: The Malaysian case. Endocrinology, Diabetes & Metabolism 5:4.
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Chun-xiao Dang, Ding Wang, Xiao Yu, Peng-fei Liu & Jin-xing Liu. (2022) Exploring the relationship between osteoporosis and polycystic ovary syndrome based on bioinformatics. Medicine 101:25, pages e29434.
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Malgorzata Bukowiecka-Matusiak, Izabela Burzynska-Pedziwiatr & Lucyna A. Wozniak. 2022. Nutrition and Functional Foods in Boosting Digestion, Metabolism and Immune Health. Nutrition and Functional Foods in Boosting Digestion, Metabolism and Immune Health 55 75 .
Fawzy Ali Saad. (2021) Proteomics: an emerging tool for the discovery of bone mineral density molecular pathways. Journal of Proteins and Proteomics 12:4, pages 247-256.
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Gareth Ryan, Richard Magony, Hilary Gortler, Charles Godbout, Emil H. Schemitsch & Aaron Nauth. (2021) Systemically impaired fracture healing in small animal research: A review of fracture repair models. Journal of Orthopaedic Research 39:7, pages 1359-1367.
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Chung-Yuan Yang, Jerry Cheng-Yen Lai, Wei-Lun Huang, Chiao-Lin Hsu & Shaw-Ji Chen. (2021) Effects of sex, tobacco smoking, and alcohol consumption osteoporosis development: Evidence from Taiwan biobank participants. Tobacco Induced Diseases 19:June, pages 1-8.
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Addis Sisay Gedamu, Kassahun Sewunet Ademe, Ayele Samuel Anteneh, Nega Abebe Dires & Tegegne Kirubel Dagnaw. (2021) Self-care practice and associated factors among type 2 adult diabetic patients on follow up clinic of Dessie referral hospital, Northeast Ethiopia. Clinical Journal of Nursing Care and Practice 5:1, pages 031-037.
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Ursula Heilmeier, Gabby B. Joseph, Courtney Pasco, Nhan Dinh, Soheyla Torabi, Karin Darakananda, Jiwon Youm, Julio Carballido-Gamio, Andrew J. Burghardt, Thomas M. Link & Galateia J. Kazakia. (2021) Longitudinal Evolution of Bone Microarchitecture and Bone Strength in Type 2 Diabetic Postmenopausal Women With and Without History of Fragility Fractures—A 5-Year Follow-Up Study Using High Resolution Peripheral Quantitative Computed Tomography. Frontiers in Endocrinology 12.
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Kun Yang, Huilei Miao, Ruijie Zhao, Xiling Wu, Bo Liu, Shuiqiao Zheng, Dan Huang & Zhao Ping. (2021) Association between serum uric acid and bone mineral density in patients with type 2 diabetes. Medicine 100:17, pages e25733.
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Hae Sang Lee & Jin Soon Hwang. (2020) Impact of Type 2 Diabetes Mellitus and Antidiabetic Medications on Bone Metabolism. Current Diabetes Reports 20:12.
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Mehrdad Abdinian, Mohammad Mahdi Salehi, Mojgan Mortazavi, Hassan Salehi & Maryam Kazemi Naeini. (2020) Comparison of dental and skeletal indices between patients under haemodialysis and peritoneal dialysis with healthy individuals in digital panoramic radiography. Dentomaxillofacial Radiology, pages 20200108.
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Wei Zhao, Weilin Zhang, Hongdong Ma & Maowei Yang. (2020) NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis. Scientific Reports 10:1.
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Jiawen Deng, Umaima Abbas, Oswin Chang, Thanansayan Dhivagaran, Stephanie Sanger & Anthony Bozzo. (2020) Antidiabetic and antiosteoporotic pharmacotherapies for prevention and treatment of type 2 diabetes-induced bone disease: protocol for two network meta-analyses. BMJ Open 10:1, pages e034741.
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Mei Ha, Jun Chen, Xiaojuan Zhang, Hong Yang & Changjiang Liu. (2019) Relationships of social support, health‐promoting lifestyles, glycemic control, and bone turnover among adults with type 2 diabetes. Japan Journal of Nursing Science 17:1.
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Mohammad Ali Moni, M. Babul Islam, Md Rezanur Rahman, Md Rashed-Al-Mahfuz, Md Abdul Awal, Sheikh Mohammed Shariful Islam, Md. Nurul Haque Mollah & Julian M. W. Quinn. (2020) Network-Based Computational Approach to Identify Delineating Common Cell Pathways Influencing Type 2 Diabetes and Diseases of Bone and Joints. IEEE Access 8, pages 1486-1497.
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Sain S. Safarova. (2019) Alterations of Bone Metabolism in Patients with Diabetes Mellitus. International Journal of Endocrinology 2019, pages 1-5.
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Wei Zhao, Wei-Lin Zhang, Bo Yang, Jun Sun & Mao-Wei Yang. (2019) NIPA2 regulates osteoblast function via its effect on apoptosis pathways in type 2 diabetes osteoporosis. Biochemical and Biophysical Research Communications 513:4, pages 883-890.
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Brendon Stubbs, Christoph Mueller, Fiona Gaughran, John Lally, Davy Vancampfort, Sarah E. Lamb, Ai Koyanagi, Shalini Sharma, Robert Stewart & Gayan Perera. (2018) Predictors of falls and fractures leading to hospitalization in people with schizophrenia spectrum disorder: A large representative cohort study. Schizophrenia Research 201, pages 70-78.
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Pijun Yan, Zhihong Zhang, Qin Wan, Jianhua Zhu, Hua Li, Chenlin Gao, Hongyan Ma & Yong Xu. (2018) Association of serum uric acid with bone mineral density and clinical fractures in Chinese type 2 diabetes mellitus patients: A cross-sectional study. Clinica Chimica Acta 486, pages 76-85.
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S. C. DeShields & T. D. Cunningham. (2018) Comparison of osteoporosis in US adults with type 1 and type 2 diabetes mellitus. Journal of Endocrinological Investigation 41:9, pages 1051-1060.
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Sook Lim, Mohd Zalilah, Yit Chin, Vasudevan Ramachandran & Yoke Chan. (2018) Dietary Acid Load, IGF-1 Single Nucleotide Polymorphism and Bone Resorption among Postmenopausal Chinese Women. Nutrients 10:7, pages 915.
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Xiangqun Deng, Min Xu, Moyu Shen & Jinluo Cheng. (2018) Effects of Type 2 Diabetic Serum on Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells. Journal of Diabetes Research 2018, pages 1-9.
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Ah-hyun Kang, Dong-kun Han, Hye-jin Seo, Jae-yeon Sung, Ju-hyun Oh, Yu-ra Lee, Hyung-chul Lee, Guk-hyun Um & Woo-sub Song. (2018) A Case of Korean-Western Medical Treatment of a Diabetic Patient Admitted with Lumbar Burst Fracture. The Journal of Internal Korean Medicine 39:2, pages 107-115.
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Shaymaa Abdalwahed Abdulameer, Mohanad Naji Sahib & Syed Azhar Syed Sulaiman. (2018) The Prevalence of Osteopenia and Osteoporosis Among Malaysian Type 2 Diabetic Patients Using Quantitative Ultrasound Densitometer. The Open Rheumatology Journal 12:1, pages 50-64.
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C. Sarodnik, S.P.G. Bours, N.C. Schaper, J.P. van den Bergh & T.A.C.M. van Geel. (2018) The risks of sarcopenia, falls and fractures in patients with type 2 diabetes mellitus. Maturitas 109, pages 70-77.
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Liting Guo, Zhihong Gao & Huanqi Ge. (2017) Effects of serum 25-hydroxyvitaminD level on decreased bone mineral density at femoral neck and total hip in Chinese type 2 diabetes. PLOS ONE 12:11, pages e0188894.
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Catalina Poiana & Cristina Capatina. (2017) Fracture Risk Assessment in Patients With Diabetes Mellitus. Journal of Clinical Densitometry 20:3, pages 432-443.
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