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Original Research

Fracture risk associated with continuation versus discontinuation of bisphosphonates after 5 years of therapy in patients with primary osteoporosis: a systematic review and meta-analysis

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Pages 157-166 | Published online: 09 May 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Tao Gu, Debra F Eisenberg Lawrence, Judith J Stephenson & Jingbo Yu. (2016) Physicians’ perspectives on the treatment of osteoporosis patients with bisphosphonates. Clinical Interventions in Aging 11, pages 1-8.
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P. Anagnostis & J. C. Stevenson. (2015) Bisphosphonate drug holidays – when, why and for how long?. Climacteric 18:sup2, pages 32-38.
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Articles from other publishers (23)

Kaveh Gharanizadeh, Hadi Ravanbod, Amir Aminian, Saeed Hatami, Ali Sherafati Chaleshtori & Soroush Kazerani. (2023) Acetabular and sacral insufficiency fractures in a patient with a long-term history of Alendronate consumption; a case report. BMC Musculoskeletal Disorders 24:1.
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Corinne Chmiel, Susanne Valentin, Uwe Beise & Felix Huber. (2023) Osteoporose. Praxis 112:4, pages 250-259.
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Kenya Ie, Shuichi Aoshima, Taku Yabuki & Steven M. Albert. (2021) A narrative review of evidence to guide deprescribing among older adults. Journal of General and Family Medicine 22:4, pages 182-196.
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Bosy Azmy Abd E, Marwa Tarek Ebra & Hanaa Khairy Moh. (2021) Salvia officinalis Extract and 17β-Estradiol Suppresses Ovariectomy Induced Osteoporosis in Female Rats. Pakistan Journal of Biological Sciences 24:3, pages 434-444.
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D. Sanchez-Rodriguez, P. Bergmann, J.J. Body, E. Cavalier, E. Gielen, S. Goemaere, B. Lapauw, MR Laurent, S. Rozenberg, G. Honvo, C. Beaudart & O. Bruyère. (2020) The Belgian Bone Club 2020 guidelines for the management of osteoporosis in postmenopausal women. Maturitas 139, pages 69-89.
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Yeon-Hui Jeong, Haeng Jeon Hur, Ae Sin Lee, Sang Hee Lee & Mi Jeong Sung. (2020) Amaranthus mangostanus Inhibits the Differentiation of Osteoclasts and Prevents Ovariectomy-Induced Bone Loss . Evidence-Based Complementary and Alternative Medicine 2020, pages 1-11.
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Henry J Woodford & James Fisher. (2019) New horizons in deprescribing for older people. Age and Ageing 48:6, pages 768-775.
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Matthew J. Stinson, Samuel Gurevitz & Anna Carrigan. (2019) Deprescribing at the end of life in older patients. JAAPA 32:7, pages 20-24.
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Y. Su, F.T.T. Lai, B.H.K. Yip, J.C.S. Leung & T.C.Y. Kwok. (2018) Cost-effectiveness of osteoporosis screening strategies for hip fracture prevention in older Chinese people: a decision tree modeling study in the Mr. OS and Ms. OS cohort in Hong Kong. Osteoporosis International 29:8, pages 1793-1805.
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Wagdy Khalil Bas, Hoda Fahim Bool, Naglaa Abd El-Mak & Gehan El-Tabie El-Bassyou. (2018) Ameliorative Effects of Brachidontes variabilis Calcium Carbonate Against Bone Loss in Ovariectomized Rats. International Journal of Pharmacology 14:4, pages 477-487.
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Bongkyun Park, Hae Seong Song, Jeong Eun Kwon, Se Min Cho, Seon-A Jang, Mi Yeon Kim & Se Chan Kang. (2017) Effects of Salvia miltiorrhiza extract with supplemental liquefied calcium on osteoporosis in calcium-deficient ovariectomized mice. BMC Complementary and Alternative Medicine 17:1.
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Nina M. Bemben. (2016) Deprescribing: An Application to Medication Management in Older Adults. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 36:7, pages 774-780.
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Sarah Schilling, Alexander Waizenhöfer & Wolfgang Lehmann. (2016) Diagnostik und Therapie der Osteoporose in der Orthopädie. Orthopädie & Rheuma 19:3, pages 27-34.
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Smita Nayak & Susan L Greenspan. (2016) Cost-Effectiveness of Osteoporosis Screening Strategies for Men. Journal of Bone and Mineral Research 31:6, pages 1189-1199.
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Jarmo Saarelainen, Saara Hassi, Risto Honkanen, Heli Koivumaa-Honkanen, Joonas Sirola, Heikki Kröger, Marja H. Komulainen & Marjo Tuppurainen. (2016) Bone loss and wrist fractures after withdrawal of hormone therapy: The 15-year follow-up of the OSTPRE cohort. Maturitas 85, pages 49-55.
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Eun-Jung Lee, Jung-Lye Kim, Yun-Ho Kim, Min-Kyung Kang, Ju-Hyun Gong & Young-Hee Kang. (2014) Phloretin promotes osteoclast apoptosis in murine macrophages and inhibits estrogen deficiency-induced osteoporosis in mice. Phytomedicine 21:10, pages 1208-1215.
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Hyun Jung Koo, Eun-Hwa Sohn, Ye-Jin Kim, Seon-A Jang, Seung Namkoong & Se Chan Kang. (2014) Effect of the combinatory mixture of Rubus coreanus Miquel and Astragalus membranaceus Bunge extracts on ovariectomy-induced osteoporosis in mice and anti-RANK signaling effect. Journal of Ethnopharmacology 151:2, pages 951-959.
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María Rosa Villar Vicente, Segundo Seclén Santisteban & Antonio Becerra Fernández. 2014. El hueso en las enfermedades endocrinas y nutricionales. El hueso en las enfermedades endocrinas y nutricionales 169 191 .
Ja-Young JangJingmei CaiJihyun KimJangbeen KyungDajeong KimEhn-Kyoung ChoiYoungeun KimKwang-Sei KimDongsun ParkHyun-Gu KangYun-Bae Kim. (2013) Specific nephrotoxicity and cardiotoxicity of BT-CAL®, Sigma Anti-bonding Molecule Calcium Carbonate, in mice. Laboratory Animal Research 29:1, pages 7.
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L. Bondo, P. Eiken & B. Abrahamsen. (2012) Analysis of the association between bisphosphonate treatment survival in Danish hip fracture patients—a nationwide register-based open cohort study. Osteoporosis International 24:1, pages 245-252.
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J. Andrici, M. Tio & G. D. Eslick. (2012) Meta-analysis: oral bisphosphonates and the risk of oesophageal cancer. Alimentary Pharmacology & Therapeutics 36:8, pages 708-716.
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Pooneh Salari. (2011) Successes in Understanding Pathophysiology of Osteoporosis. International Journal of Pharmacology 7:6, pages 677-678.
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So-Young ChoiDongsun ParkGoeun YangSun Hee LeeDae Kwon BaeSeock-Yeon HwangPaul K LeeYun-Bae KimIll-Hwa KimHyun-Gu Kang. (2011) Effects of Sigma Anti-bonding Molecule Calcium Carbonate on bone turnover and calcium balance in ovariectomized rats. Laboratory Animal Research 27:4, pages 301.
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