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Original Research

Fracture risk associated with continuation versus discontinuation of bisphosphonates after 5 years of therapy in patients with primary osteoporosis: a systematic review and meta-analysis

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Pages 157-166 | Published online: 09 May 2011

References

  • HanleyDAJosseRGPrevention and management of osteoporosis: consensus statements from the Scientific Advisory Board of the Osteoporosis Society of Canada: 1. IntroductionCMAJ199615579219338837540
  • EbelingPRClinical practice. Osteoporosis in menN Engl J Med2008358141474148218385499
  • BrownJPJosseRGScientific Advisory Council of the Osteoporosis Society of Canada. Clinical practice guidelines for the diagnosis and management of osteoporosis in CanadaCMAJ200216710 Suppl134
  • DelmasPDTreatment of postmenopausal osteoporosisLancet200235993222018202612076571
  • CranneyAWellsGWillanAMeta-analyses of therapies for postmenopausal osteoporosis. II. Meta-analysis of alendronate for the treatment of postmenopausal womenEndocr Rev200223450851612202465
  • PapapoulosSEBisphosphonates for postmenopausal osteoporosisPrimer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism7th edRosenCJWashingtonASBMR2008237
  • OttSMLong-term safety of bisphosphonatesJ Clin Endocrinol Metab20059031897189915758064
  • ShebbaAOsteoporosis: how long should we treat?Curr Opin Endocrinol Diabetes Obs2008156502507
  • NeviaserASLaneJMLenartBALow-energy femoral shaft fractures associated with alendronate useJ Ortho Trauma2008225346350
  • OdvinaCVZerwekhJERaoDSSeverely suppressed bone turnover; a potential complication of alendronate therapyJ Clin Endocrinol Metab20059031294130115598694
  • GoddardMSReidKRJohnstonJCKhanujaHSAtraumatic bilateral femur fracture in long-term bisphosphonate useOrthopedics2009328piiorthosupersite.com/view.asp?rID=4193310.3928/01477447-20090624-27.19708622
  • KhanAASandorGKDoreEBisphosphonate associated osteonecrosis of the jawJ Rheumatol200936347850919286860
  • LokeYKJeevananthamVSinghSBisphosphonates and atrial fibrillation: systematic review and meta-analysisDrug Saf200932321922819338379
  • HaleemSLutchmanLMayahiRMortality following hip fracture: trends and geographical variations over the last 40 yearsInjury200839101157116318653186
  • BentlerSELiuLObrizanMThe aftermath of hip fracture: discharge placement, functional status change, and mortalityAm J Epidemiol2009170101290129919808632
  • HigginsJPTGreenSThe Cochrane CollaborationCochrane Handbook for Systematic Reviews of Interventions Version 5.0.2 [updated September 2009]. http://www.cochrane-handbook.org. Accessed March 30, 2011
  • BlackDMSchwartzAVEnsrudKEEffects of continuing or stopping alendronate after 5 years of treatment. The fracture intervention trial long-term extension (FLEX): a randomized trialJAMA2006296242927293817190893
  • MillerPDWattsNBLicataAACyclical etidronate in the treatment of postmenopausal osteoporosis: Efficacy and safety after seven years of treatmentAm J Med199710364684769428829
  • BoneHGHoskingDDevogelaerJPTen years’ experience with alendronate for osteoporosis in postmenopausal womenN Engl J Med2004350121189119915028823
  • ToninoRPMeunierPJEmkeyRSkeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic womenJ Clin Endocrinol Metab20008593109311510999794
  • BlackDMCummingsSRKarpfDBRandomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research GroupLancet19963489041153515418950879
  • WattsNBDiabDLLong-term use of bisphosphonates in osteoporosisJ Clin Endocrinol Metab20109541555156520173017
  • BaggerYZTankoLBAlexandersenPAlendronate has a residual effect on bone mass in postmenopausal Danish women up to 7 years after treatment withdrawalBone200333330130713678770
  • CurtisJRWestfallAOChengHRisk of hip fracture after bisphosphonate discontinuation: implications for a drug holidayOsteoporos Int200819111613162018483689
  • CooperCBeyond daily dosing: clinical experienceBone2006384 Suppl 1S13S1716520105
  • GeusensPBisphosphonates for postmenopausal osteoporosis: determining duration of treatmentCurr Osteoporos Rep200971121719239824
  • BriotKTremollieresFThomasTRouxCHow long should patients take medications for postmenopausal osteoporosis?Joint Bone Spine2007741243117223374
  • RosenCJBrownSAA rational approach to evidence gaps in the management of osteoporosisAm J Med2005118111183118916271898
  • LarocheMTreatment of osteoporosis: all the questions we still cannot answerAm J Med2008121974474718724959