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Review

Pathogenesis and clinical and economic consequences of postoperative ileus

Pages 87-89 | Published online: 01 Jul 2010

Keep up to date with the latest research on this topic with citation updates for this article.

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Gary M. Oderda, Anthony J. Senagore, Kellie Morland, Sheikh Usman Iqbal, Marla Kugel, Sizhu Liu & Ashraf S. Habib. (2019) Opioid-related respiratory and gastrointestinal adverse events in patients with acute postoperative pain: prevalence, predictors, and burden. Journal of Pain & Palliative Care Pharmacotherapy 33:3-4, pages 82-97.
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Tong J. Gan, Scott B. Robinson, Gary M. Oderda, Richard Scranton, Jodie Pepin & Sonia Ramamoorthy. (2015) Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries. Current Medical Research and Opinion 31:4, pages 677-686.
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Articles from other publishers (31)

Logan A. Reed, Alexander K. Mihas, Travis A. Fortin, Guna Pratheep, Sakthivel Rajaram Manoharan, Steven M. Theiss & Vibhu Krishnan Viswanathan. (2022) Risk Factors for Postoperative Ileus After Thoracolumbar and Lumbar Spinal Fusion Surgery: Systematic Review and Meta-Analysis. World Neurosurgery 168, pages e381-e392.
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Emre Yilmaz, Eric Benca, Akil P. Patel, Sarah Hopkins, Ronen Blecher, Amir Abdul-Jabbar, Thomas M. O’Lynnger, Rod J. Oskouian, Daniel C. Norvell & Jens Chapman. (2021) What Are Risk Factors for an Ileus After Posterior Spine Surgery?—A Case Control Study. Global Spine Journal 12:7, pages 1407-1411.
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Tibor Docsa, Adám Sipos, Charles S. Cox & Karen Uray. (2022) The Role of Inflammatory Mediators in the Development of Gastrointestinal Motility Disorders. International Journal of Molecular Sciences 23:13, pages 6917.
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Tyler McKechnie, Tharani Anpalagan, Simarpreet Ichhpuniani, Yung Lee, Karim Ramji & Cagla Eskicioglu. (2021) Selective Opioid Antagonists Following Bowel Resection for Prevention of Postoperative Ileus: a Systematic Review and Meta-analysis. Journal of Gastrointestinal Surgery 25:6, pages 1601-1624.
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Li-Hua Peng, Wen-Jian Wang, Jing Chen, Ju-Ying Jin, Su Min & Pei-Pei Qin. (2021) Implementation of the pre-operative rehabilitation recovery protocol and its effect on the quality of recovery after colorectal surgeries. Chinese Medical Journal 134:23, pages 2865-2873.
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Jonas Van Dingenen, Leen Pieters, Elien Van Nuffel & Romain A. Lefebvre. (2019) Hemin reduces postoperative ileus in a heme oxygenase 1‐dependent manner while dimethyl fumarate does without heme oxygenase 1‐induction. Neurogastroenterology & Motility 32:4.
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İbrahim KARABULUT, Ali Haydar YILMAZ & Fatih YILMAZEL. (2020) The Efficacy of Chewing Gum in Postoperative Ileus Management After Robot Assisted Laparoscopic Radical Prostatectomy: A Prospective Randomized StudyRobot Yardımlı Laparoskopik Radikal Prostatektomi Sonrası Oluşan Fizyolojik İleus Yönetiminde Sakız Çiğnemenin Etkinliği. Journal of Contemporary Medicine 10:1, pages 96-101.
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Tibor Docsa, Deepa Bhattarai, Adam Sipos, Charles E. Wade, Charles S. CoxJrJr & Karen Uray. (2019) CXCL1 is upregulated during the development of ileus resulting in decreased intestinal contractile activity. Neurogastroenterology & Motility 32:3.
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Nkechinye Omesiete, Carolina Martinez, Viraj Pandit, Yadira Villalvazo, Hunter Jecius, Eli Thompson, Meleesa Norcera & Valentine Nfonsam. (2019) Restricting Intraoperative Fluid Volume Allows Earlier Return of Bowel Function After Colon and Rectal Surgery. Journal of Surgical Research 244, pages 130-135.
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Jee Soo Park, Jongchan Kim, Won Sik Jang, Ji Eun Heo, Ahmed Elghiaty, Koon Ho Rha, Young Deuk Choi & Won Sik Ham. (2018) Management of postoperative ileus after robot-assisted laparoscopic prostatectomy. Medicine 97:44, pages e13036.
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Traci L. Hedrick, Matthew D. McEvoy, Michael (Monty) G. Mythen, Roberto Bergamaschi, Ruchir Gupta, Stefan D. Holubar, Anthony J. Senagore, Tong Joo Gan, Andrew D. Shaw, Julie K. M. Thacker, Timothy E. Miller, Paul E. Wischmeyer, Franco Carli, David C. Evans, Sarah Guilbert, Rosemary Kozar, Aurora Pryor, Robert H. Thiele, Sotiria Everett, Mike Grocott, Ramon E. Abola, Elliott Bennett-Guerrero, Michael L. Kent, Liane S. Feldman & Julio F. FioreJrJr. (2018) American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Gastrointestinal Dysfunction Within an Enhanced Recovery Pathway for Elective Colorectal Surgery. Anesthesia & Analgesia 126:6, pages 1896-1907.
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Bridgette Kram, Maegan Greenland, Mollie Grant, Michael E. Campbell, Charlotte Wells & Courtney Sommer. (2018) Efficacy and Safety of Subcutaneous Neostigmine for Ileus, Acute Colonic Pseudo-obstruction, or Refractory Constipation. Annals of Pharmacotherapy 52:6, pages 505-512.
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Victor E. Pricolo, Patrick Fei, Scott Crowley, Virginia Camisa & Matteo Bonvini. (2018) A novel enhanced recovery protocol, combining multimodal analgesia with liposomal bupivacaine and pharmacologic intervention, reduces parenteral opioid use and hospital length of stay after colectomy – A cohort study. International Journal of Surgery Open 13, pages 24-28.
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Daniel J. Kagedan & Alice C. Wei. 2018. Optimizing Outcomes for Liver and Pancreas Surgery. Optimizing Outcomes for Liver and Pancreas Surgery 229 255 .
Deborah S. Keller, Rodrigo Pedraza, Reena N. Tahilramani, Juan R. Flores-Gonzalez, Sergio Ibarra & Eric M. Haas. (2017) Impact of long-acting local anesthesia on clinical and financial outcomes in laparoscopic colorectal surgery. The American Journal of Surgery 214:1, pages 53-58.
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Unni Olsen, Jens Ivar Brox & Ida Torunn Bjørk. (2016) Preoperative bowel preparation versus no preparation before spinal surgery: A randomised clinical trial. International Journal of Orthopaedic and Trauma Nursing 23, pages 3-13.
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DS Keller, RN Tahilramani, JR Flores-Gonzalez, S. Ibarra & EM Haas. (2015) Pilot study of a novel pain management strategy: evaluating the impact on patient outcomes. Surgical Endoscopy 30:6, pages 2192-2198.
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Sacide Yildizeli Topcu & Seher Deniz Oztekin. (2016) Effect of gum chewing on reducing postoperative ileus and recovery after colorectal surgery: A randomised controlled trial. Complementary Therapies in Clinical Practice 23, pages 21-25.
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Stephanie R. Earnshaw, Teresa L. Kauf, Cheryl McDade, Michele H. Potashman, Cassandra Pauyo, Emily S. Reese & Anthony Senagore. (2015) Economic Impact of Alvimopan Considering Varying Definitions of Postoperative Ileus. Journal of the American College of Surgeons 221:5, pages 941-950.
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Stefano Trastulli, Roberto Cirocchi, Jacopo Desiderio, Andrea Coratti, Salvatore Guarino, Claudio Renzi, Alessia Corsi, Carlo Boselli, Alberto Santoro, Liliana Minelli & Amilcare Parisi. (2015) Robotic versus Laparoscopic Approach in Colonic Resections for Cancer and Benign Diseases: Systematic Review and Meta-Analysis. PLOS ONE 10:7, pages e0134062.
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Alan H. Daniels, Scott A. Ritterman & Lee E. Rubin. (2015) Paralytic Ileus in the Orthopaedic Patient. Journal of the American Academy of Orthopaedic Surgeons 23:6, pages 365-372.
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S. Berdún, E. Bombuy, O. Estrada, E. Mans, J. Rychter, P. Clavé & P. Vergara. (2015) Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery. Neurogastroenterology & Motility 27:6, pages 764-774.
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Sofia Wronski. (2015) Disminución del íleo postoperatorio mediante el uso de goma de mascar. Nursing (Ed. española) 32:2, pages 57-61.
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Fouad Aoun, Marc Zanaty, Alexandre Peltier & Roland van Velthoven. (2015) Minimal Invasive Urologic Surgery and Postoperative Ileus. The Open Access Journal of Science and Technology 3.
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Deborah S. Keller, Bridget O. Ermlich, Nicholas Schiltz, Bradley J. Champagne, Harry L. Reynolds, Sharon L. Stein & Conor P. Delaney. (2014) The Effect of Transversus Abdominis Plane Blocks on Postoperative Pain in Laparoscopic Colorectal Surgery. Diseases of the Colon & Rectum 57:11, pages 1290-1297.
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Sofia Wronski. (2014) Chew on this. Nursing 44:8, pages 19-23.
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Scott R. Kelley, Bruce G. Wolff, Jenna K. Lovely & David W. Larson. (2013) Fast-track Pathway for Minimally Invasive Colorectal Surgery with and without Alvimopan (Entereg) ™ : Which is More Cost-effective? . The American Surgeon 79:6, pages 630-633.
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Susan L. Chapelle & Geoffrey M. Bove. (2013) Visceral massage reduces postoperative ileus in a rat model. Journal of Bodywork and Movement Therapies 17:1, pages 83-88.
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Sjoerd H. W. van Bree, Andrea Nemethova, Cathy Cailotto, Pedro J. Gomez-Pinilla, Gianluca Matteoli & Guy E. Boeckxstaens. (2012) New therapeutic strategies for postoperative ileus. Nature Reviews Gastroenterology & Hepatology 9:11, pages 675-683.
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Kais Rona, J. Choi, G. Sigle, S. Kidd, G. Ault & A. J. Senagore. (2012) Enhanced Recovery Protocol: Implementation at a County Institution with Limited Resources. The American Surgeon 78:10, pages 1041-1044.
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Melissa Thompson & Barbara Magnuson. (2012) Management of Postoperative Ileus. Orthopedics 35:3, pages 213-217.
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