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Original Research

Eggshell membrane: A possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies

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Pages 235-240 | Published online: 18 May 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Karen J. Wedekind, Kevin J. Ruff, Cindy A. Atwell, Joseph L. Evans & Alison M. Bendele. (2017) Beneficial effects of natural eggshell membrane (NEM) on multiple indices of arthritis in collagen-induced arthritic rats. Modern Rheumatology 27:5, pages 838-848.
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Kevin J Ruff, Kenneth J Kopp, Pamela Von Behrens, Mark Lux, Matthew Mahn & Matthew Back. (2016) Effectiveness of NEM® brand eggshell membrane in the treatment of suboptimal joint function in dogs: a multicenter, randomized, double-blind, placebo-controlled study. Veterinary Medicine: Research and Reports 7, pages 113-121.
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Karen J Wedekind, Josie A Coverdale, Thomas R Hampton, Cindy A Atwell, Roy H Sorbet, Jenea Lunnemann, Robert J Harrell, Laura Greiner, Nancy K Keith, Joseph L Evans, Junmei Zhao & Chris D Knight. (2015) Efficacy of an equine joint supplement, and the synergistic effect of its active ingredients (chelated trace minerals and natural eggshell membrane), as demonstrated in equine, swine, and an osteoarthritis rat model. Open Access Animal Physiology 7, pages 13-27.
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Kevin J Ruff, Paul L Durham, Austin O’Reilly & F Daniel Long. (2015) Eggshell membrane hydrolyzates activate NF-κB in vitro: possible implications for in vivo efficacy. Journal of Inflammation Research 8, pages 49-57.
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Ana Santana, Armindo Melo, Tânia Tavares & Isabel M. P. L. V. O. Ferreira. (2016) Biological activities of peptide concentrates obtained from hydrolysed eggshell membrane byproduct by optimisation with response surface methodology. Food & Function 7:11, pages 4597-4604.
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