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Clinical Lipidology Volume 4, 2009 - Issue 1
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Liver X receptors as therapeutic targets for managing cholesterol: implications for inflammatory conditions

Yuan ZhangUniversity of Toronto, Faculty of Pharmacy, 144 College Street, Toronto, Ontario, M5S 3M2, Canada, Tel.: +1 416 946 3466, Fax.: +1 416 978 8511, E-mail: [email protected]
,
Jessica F. ChanUniversity of Texas Southwestern Medical Center, Department of Pharmacology, 6001 Forest Park Rd, Dallas, TX 75390-9050, USA, Tel.: +1 214 645 5967, Fax.: +1 214 645 5969, E-mail: [email protected]
&
Carolyn L. CumminsUniversity of Toronto, Faculty of Pharmacy, 144 College Street, Toronto, Ontario, M5S 3M2, Canada, Tel.: +1 416 946 3466, Fax.: +1 416 978 8511, E-mail: [email protected]Correspondence[email protected]
Pages 29-40 | Published online: 18 Jan 2017

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Madhav Sachar & Xiaochao Ma. (2013) Nuclear receptors in herb–drug interactions. Drug Metabolism Reviews 45:1, pages 73-78.
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Anastasia V. Poznyak, Vasily N. Sukhorukov, Ilya I. Eremin, Irina I. Nadelyaeva, Nikita A. Gutyrchik & Alexander N. Orekhov. (2023) HDL-Based Therapy: Vascular Protection at All Stages. Biomedicines 11:3, pages 711.
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Yan Li, Carol A. Pollock & Sonia Saad. (2021) Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and Overnutrition. Genes 12:11, pages 1653.
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Minoru Koura, Yuki Yamaguchi, Sayaka Kurobuchi, Hisashi Sumida, Yuichiro Watanabe, Takashi Enomoto, Takayuki Matsuda, Ayumu Okuda, Tomoaki Koshizawa, Yuki Matsumoto & Kimiyuki Shibuya. (2016) Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist. Bioorganic & Medicinal Chemistry 24:16, pages 3436-3446.
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Minoru Koura, Takayuki Matsuda, Ayumu Okuda, Yuichiro Watanabe, Yuki Yamaguchi, Sayaka Kurobuchi, Yuuki Matsumoto & Kimiyuki Shibuya. (2015) Design, synthesis and pharmacology of 1,1-bistrifluoromethylcarbinol derivatives as liver X receptor β-selective agonists. Bioorganic & Medicinal Chemistry Letters 25:13, pages 2668-2674.
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Huan-Ling Yu, Shan Dong, Li-Fang Gao, Li Li, Yuan-Di Xi, Wei-Wei Ma, Lin-Hong Yuan & Rong Xiao. (2015) Global DNA methylation was changed by a maternal high-lipid, high-energy diet during gestation and lactation in male adult mice liver. British Journal of Nutrition 113:7, pages 1032-1039.
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Takayuki Matsuda, Ayumu Okuda, Yuichiro Watanabe, Tohru Miura, Hidefumi Ozawa, Ayako Tosaka, Koichi Yamazaki, Yuki Yamaguchi, Sayaka Kurobuchi, Minoru Koura & Kimiyuki Shibuya. (2015) Design and discovery of 2-oxochromene derivatives as liver X receptor β-selective agonists. Bioorganic & Medicinal Chemistry Letters 25:6, pages 1274-1278.
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Baihua Hu, Rayomand J. Unwalla, Igor Goljer, James W. Jetter, Elaine M. Quinet, Thomas J. Berrodin, Michael D. Basso, Irene B. Feingold, Annika Goos Nilsson, Anna Wilhelmsson, Mark J. Evans & Jay E. Wrobel. (2010) Identification of Phenylsulfone-Substituted Quinoxaline (WYE-672) as a Tissue Selective Liver X-receptor (LXR) Agonist. Journal of Medicinal Chemistry 53:8, pages 3296-3304.
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Baihua Hu, Ron Bernotas, Rayomand Unwalla, Michael Collini, Elaine Quinet, Irene Feingold, Annika Goos-Nilsson, Anna Wilhelmsson, Ponnal Nambi, Mark Evans & Jay Wrobel. (2010) Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRβ and low blood–brain penetration. Bioorganic & Medicinal Chemistry Letters 20:2, pages 689-693.
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