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Pharmacogenomics Volume 14, 2013 - Issue 3
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Research Article

Characterization of the CYP2D6 Gene Locus and Metabolic Activity in Indo- and Afro-Trinidadians: Discovery of Novel Allelic Variants

Lazara Karelia Montané Jaime1 Pharmacology Unit, Department of Paraclinical Sciences, Faculty of Medical Sciences, The University of The West Indies, St Augustine, Trinidad &Tobago
,
Anthony Lalla1 Pharmacology Unit, Department of Paraclinical Sciences, Faculty of Medical Sciences, The University of The West Indies, St Augustine, Trinidad &Tobago
,
Werner Steimer2 Institut für Klinische Chemie & Pathobiochemie Klinikum rechts der Isar, Technische Universität München. Ismaninger Str. 22, 81675München, Germany
&
Andrea Gaedigk3 Division of Clinical Pharmacology & Medical Toxicology, The Children‘s Mercy Hospital & Clinics, 2401 Gillham Rd, Kansas City, MO62108, [email protected]
Pages 261-276 | Published online: 11 Feb 2013

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E Ricky Chan, Rajeev K Mehlotra, Karim A Pirani, Arsene C Ratsimbasoa, Scott M Williams, Andrea Gaedigk & Peter A Zimmerman. (2022) CYP2D6 Gene Resequencing in the Malagasy, a Population at the Crossroads between Asia and Africa: A Pilot Study. Pharmacogenomics 23:5, pages 315-325.
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Aarthi Manoharan, Deepak Gopal Shewade, Pradeep Anand Ravindranath, Ravi Philip Rajkumar, Vedam L Ramprasad, Surendiran Adithan & Solai Elango Damodaran. (2019) Resequencing CYP2D6 Gene in Indian Population: CYP2D6*41 Identified as the Major Reduced Function Allele. Pharmacogenomics 20:10, pages 719-729.
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Lazara Karelia Montané Jaime, Jeffrey Paul, Anthony Lalla, George Legall & Andrea Gaedigk. (2018) Impact of CYP2D6 on Venlafaxine Metabolism in Trinidadian Patients with Major Depressive Disorder. Pharmacogenomics 19:3, pages 197-212.
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Anne B Koopmans, David J Vinkers, Petra JA Gelan, Hans W Hoek & Peter N van Harten. (2017) CYP2D6 and CYP2C19 Genotyping in Psychiatric Patients on Psychotropic Medication in the Former Dutch Antilles. Pharmacogenomics 18:10, pages 1003-1012.
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Carolina Céspedes-Garro, María-Eugenia G Naranjo, Fernanda Rodrigues-Soares, Adrián LLerena, Jorge Duconge, Lazara K Montané-Jaime, Hilda Roblejo, Humberto Fariñas, María de los A Campos, Ronald Ramírez, Víctor Serrano, Carmen I Villagrán & Eva M Peñas-LLedó. (2016) Pharmacogenetic Research Activity in Central America and the Caribbean: A Systematic Review. Pharmacogenomics 17:15, pages 1707-1724.
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Rashmi R Shah, Andrea Gaedigk, Adrián LLerena, Michel Eichelbaum, Julia Stingl & Robert L Smith. (2016) CYP450 Genotype and Pharmacogenetic Association Studies: a Critical Appraisal. Pharmacogenomics 17:3, pages 259-275.
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Andrea Gaedigk, Carles Garcia-Ribera, Hye-Eun Jeong, Jae-Gook Shin & Juanjo Hernandez-Sanchez. (2014) Resolution of a Clinical AmpliChip CYP450 Test™ No Call: Discovery and Characterization of Novel CYP2D6*1 Haplotypes. Pharmacogenomics 15:9, pages 1175-1184.
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Britt I Drögemöller, Galen EB Wright & Louise Warnich. (2014) Considerations for rare variants in drug metabolism genes and the clinical implications. Expert Opinion on Drug Metabolism & Toxicology 10:6, pages 873-884.
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